Sfoglia per Autore
Emergence of KRAS mutations and acquired resistance to anti EGFR therapy in colorectal cancer
2012-01-01 Misale, S; Yaeger, R; Hobor, S; Scala, E; Janakiraman, M; Liska, D; Valtorta, E; Schiavo, R; Buscarino, M; Siravegna, G; Bencardino, K; Cercek, A; Chen, Ct; Veronese, S; Zanon, C; Sartore-Bianchi, A; Gambacorta, M; Gallicchio, M; Vakiani, E; Boscaro, V; Medico, E; Weiser, M; Siena, S; Di Nicolantonio, F; Solit, D; Bardelli, A.
Amplification of the MET Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer.
2013-01-01 Bardelli A*;Corso S*;Bertotti A*;Hobor S;Valtorta E;Siravegna G;Sartore-Bianchi A;Scala E;Cassingena A;Zecchin D;Apicella M;Migliardi G;Galimi F;Lauricella C;Zanon C;Perera T;Veronese S;Corti G;Amatu A;Gambacorta M;Diaz LA Jr;Sausen M;Velculescu VE;Comoglio P;Trusolino L;Di Nicolantonio F;Giordano S;Siena S (*Co-First Authors)
Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies
2014-01-01 C. Bettegowda;M. Sausen;R. J. Leary;I. Kinde;Y. Wang;N. Agrawal;B. R. Bartlett;H. Wang;B. Luber;R. M. Alani;E. S. Antonarakis;N. S. Azad;A. Bardelli;H. Brem;J. L. Cameron;C. C. Lee;L. A. Fecher;G. L. Gallia;P. Gibbs;D. Le;R. L. Giuntoli;M. Goggins;M. D. Hogarty;M. Holdhoff;S.-M. Hong;Y. Jiao;H. H. Juhl;J. J. Kim;G. Siravegna;D. A. Laheru;C. Lauricella;M. Lim;E. J. Lipson;S. K. N. Marie;G. J. Netto;K. S. Oliner;A. Olivi;L. Olsson;G. J. Riggins;A. Sartore-Bianchi;K. Schmidt;l.-M. Shih;S. M. Oba-Shinjo;S. Siena;D. Theodorescu;J. Tie;T. T. Harkins;S. Veronese;T.-L. Wang;J. D. Weingart;C. L. Wolfgang;L. D. Wood;D. Xing;R. H. Hruban;J. Wu;P. J. Allen;C. M. Schmidt;M. A. Choti;V. E. Velculescu;K. W. Kinzler;B. Vogelstein;N. Papadopoulos;L. A. Diaz
Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer
2014-01-01 S. Misale;S. Arena;S. Lamba;G. Siravegna;A. Lallo;S. Hobor;M. Russo;M. Buscarino;L. Lazzari;A. Sartore-Bianchi;K. Bencardino;A. Amatu;C. Lauricella;E. Valtorta;S. Siena;F. Di Nicolantonio;A. Bardelli
Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance.
2014-01-01 Siravegna G;Bardelli A
Minimal residual disease in breast cancer: in blood veritas.
2014-01-01 Siravegna G; Bardelli A
Molecular heterogeneity and receptor coamplification drive resistance to targeted therapy in MET-Amplified esophagogastric cancer
2015-01-01 Kwak, Eunice L.; Ahronian, Leanne G.; Siravegna, Giulia; Mussolin, Benedetta; Godfrey, Jason T.; Clark, Jeffrey W.; Blaszkowsky, Lawrence S.; Ryan, David P.; Lennerz, Jochen K.; John Iafrate, A.; Bardelli, Alberto; Hong, Theodore S.; Corcoran, Ryan B.
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients
2015-01-01 Siravegna, Giulia; Mussolin, Benedetta; Buscarino, Michela; Corti, Giorgio; Cassingena, Andrea; Crisafulli, Giovanni; Ponzetti, Agostino; Cremolini, Chiara; Amatu, Alessio; Lauricella, Calogero; Lamba, Simona; Hobor, Sebastijan; Avallone, Antonio; Valtorta, Emanuele; Rospo, Giuseppe; Medico, Enzo; Motta, Valentina; Antoniotti, Carlotta; Tatangelo, Fabiana; Bellosillo, Beatriz; Veronese, Silvio; Budillon, Alfredo; Montagut, Clara; Racca, Patrizia; Marsoni, Silvia; Falcone, Alfredo; Corcoran, Ryan B; Di Nicolantonio, Federica; Loupakis, Fotios; Siena, Salvatore; Sartore-Bianchi, Andrea; Bardelli, Alberto
Liquid biopsies to evaluate early therapeutic response in colorectal cancer
2015-01-01 Montagut, C; Siravegna, G; Bardelli, A
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer
2015-01-01 Barault, L; Amatu, A; Bleeker, F E; Moutinho, C; Falcomatà, C; Fiano, V; Cassingena, A; Siravegna, G; Milione, M; Cassoni, P; De Braud, F; Rudà, R; Soffietti, R; Venesio, T; Bardelli, A; Wesseling, P; de Witt Hamer, P; Pietrantonio, F; Siena, S; Esteller, M; Sartore-Bianchi, A; Di Nicolantonio, F
Emergence of multiple EGFR extracellular mutations during cetuximab treatment in colorectal cancer
2015-01-01 S. Arena; B. Bellosillo; G. Siravegna; A. Martinez; I. Canadas; L. Lazzari; N. Ferruz; M. Russo; S. Misale; I. Gonzalez; M. Iglesias; E. Gavilan; G. Corti; S. Hobor; G. Crisafulli; M. Salido; J. Sanchez; A. Dalmases; J. Bellmunt; G.D. Fabritiis; A. Rovira; F. Di Nicolantonio; J. Albanell; A. Bardelli; C. Montagut
Acquired resistance to the TRK inhibitor entrectinib in colorectal cancer
2016-01-01 Russo, Mariangela; Misale, Sandra; Wei, Ge; Siravegna, Giulia; Crisafulli, Giovanni; Lazzari, Luca; Corti, Giorgio; Rospo, Giuseppe; Novara, Luca; Mussolin, Benedetta; Bartolini, Alice; Cam, Nicholas; Patel, Roopal; Yan, Shunqi; Shoemaker, Robert; Wild, Robert; Di Nicolantonio, Federica; Sartore-Bianchi, Andrea; Li, Gang; Siena, Salvatore; Bardelli, Alberto
Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer
2016-01-01 Van Emburgh, Beth O; Arena, Sabrina; Siravegna, Giulia; Lazzari, Luca; Crisafulli, Giovanni; Corti, Giorgio; Mussolin, Benedetta; Baldi, Federica; Buscarino, Michela; Bartolini, Alice; Valtorta, Emanuele; Vidal, Joana; Bellosillo, Beatriz; Germano, Giovanni; Pietrantonio, Filippo; Ponzetti, Agostino; Albanell, Joan; Siena, Salvatore; Sartore-Bianchi, Andrea; Di Nicolantonio, Federica; Montagut, Clara; Bardelli, Alberto
Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition
2016-01-01 Hata, Aaron N; Niederst, Matthew J; Archibald, Hannah L; Gomez-Caraballo, Maria; Siddiqui, Faria M; Mulvey, Hillary E; Maruvka, Yosef E; Ji, Fei; Bhang, Hyo-Eun C; Krishnamurthy Radhakrishna, Viveksagar; Siravegna, Giulia; Hu, Haichuan; Raoof, Sana; Lockerman, Elizabeth; Kalsy, Anuj; Lee, Dana; Keating, Celina L; Ruddy, David A; Damon, Leah J; Crystal, Adam S; Costa, Carlotta; Piotrowska, Zofia; Bardelli, Alberto; Iafrate, Anthony J; Sadreyev, Ruslan I; Stegmeier, Frank; Getz, Gad; Sequist, Lecia V; Faber, Anthony C; Engelman, Jeffrey A
Blood circulating tumor DNA for non-invasive genotyping of colon cancer patients
2016-01-01 Siravegna, Giulia; Bardelli, Alberto
Tumor heterogeneity and Lesion-Specific response to targeted therapy in colorectal cancer
2016-01-01 Russo, Mariangela; Siravegna, Giulia; Blaszkowsky, Lawrence S.; Corti, Giorgio; Crisafulli, Giovanni; Ahronian, Leanne G.; Mussolin, Benedetta; Kwak, Eunice L.; Buscarino, Michela; Lazzari, Luca; Valtorta, Emanuele; Truini, Mauro; Jessop, Nicholas A.; Robinson, Hayley E.; Hong, Theodore S.; Mino-Kenudson, Mari; Di Nicolantonio, Federica; Thabet, Ashraf; Sartore-Bianchi, Andrea; Siena, Salvatore; Iafrate, John; Bardelli, Alberto; ^*; Corcoran, Ryan B.; ^*; ^ joint co-last authorship; *joint corresponding authorship
Clonal evolution and KRAS-MET coamplification during secondary resistance to EGFR-targeted therapy in metastatic colorectal cancer
2016-01-01 Sartore-Bianchi, Andrea; Valtorta, Emanuele; Amatu, Alessio; Veronese, Silvio; Lauricella, Calogero; Bonazzina, Erica; Siravegna, Giulia; Truini, Mauro; Bardelli, Alberto; Siena, Salvatore
MET-driven resistance to dual EGFR and BRAF blockade may be overcome by switching from EGFR to MET inhibition in BRAF mutated colorectal cancer
2016-01-01 Pietrantonio, Filippo; Oddo, Daniele; Gloghini, Annunziata; Valtorta, Emanuele; Berenato, Rosa; Barault, Ludovic; Caporale, Marta; Busico, Adele; Morano, Federica; Gualeni, Ambra Vittoria; Alessi, Alessandra; Siravegna, Giulia; Perrone, Federica; Di Bartolomeo, Maria; Bardelli, Alberto; de Braud, Filippo; Di Nicolantonio, Federica
Molecular landscape of acquired resistance to targeted therapy combinations in BRAF mutant colorectal cancer
2016-01-01 Oddo, D; Sennott, Em; Barault, L; Valtorta, E; Arena, S; Cassingena, A; Filiciotto, G; Marzolla, G; Elez, E; van Geel RM, ; Bartolini, A; Crisafulli, G; Boscaro, V; Godfrey, Jt; Buscarino, M; Cancelliere, C; Linnebacher, M; Corti, G; Truini, M; Siravegna, G; Grasselli, J; Gallicchio, M; Bernards, R; Schellens, Jh; Tabernero, J; Engelman, Ja; Sartore-Bianchi, A; Bardelli, A; Siena, S; Corcoran, Rb; Di Nicolantonio, F.
MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations
2016-01-01 Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex A.; Montagut, Clara; Di Nicolantonio, Federica; Nering, Rachel; Bardelli, Alberto
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Emergence of KRAS mutations and acquired resistance to anti EGFR therapy in colorectal cancer | 2012 | Misale, S; Yaeger, R; Hobor, S; Scala, E; Janakiraman, M; Liska, D; Valtorta, E; Schiavo, R; Buscarino, M; Siravegna, G; Bencardino, K; Cercek, A; Chen, Ct; Veronese, S; Zanon, C; Sartore-Bianchi, A; Gambacorta, M; Gallicchio, M; Vakiani, E; Boscaro, V; Medico, E; Weiser, M; Siena, S; Di Nicolantonio, F; Solit, D; Bardelli, A. | |
| Amplification of the MET Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer. | 2013 | Bardelli A*;Corso S*;Bertotti A*;Hobor S;Valtorta E;Siravegna G;Sartore-Bianchi A;Scala E;Cassingena A;Zecchin D;Apicella M;Migliardi G;Galimi F;Lauricella C;Zanon C;Perera T;Veronese S;Corti G;Amatu A;Gambacorta M;Diaz LA Jr;Sausen M;Velculescu VE;Comoglio P;Trusolino L;Di Nicolantonio F;Giordano S;Siena S (*Co-First Authors) | |
| Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies | 2014 | C. Bettegowda;M. Sausen;R. J. Leary;I. Kinde;Y. Wang;N. Agrawal;B. R. Bartlett;H. Wang;B. Luber;R. M. Alani;E. S. Antonarakis;N. S. Azad;A. Bardelli;H. Brem;J. L. Cameron;C. C. Lee;L. A. Fecher;G. L. Gallia;P. Gibbs;D. Le;R. L. Giuntoli;M. Goggins;M. D. Hogarty;M. Holdhoff;S.-M. Hong;Y. Jiao;H. H. Juhl;J. J. Kim;G. Siravegna;D. A. Laheru;C. Lauricella;M. Lim;E. J. Lipson;S. K. N. Marie;G. J. Netto;K. S. Oliner;A. Olivi;L. Olsson;G. J. Riggins;A. Sartore-Bianchi;K. Schmidt;l.-M. Shih;S. M. Oba-Shinjo;S. Siena;D. Theodorescu;J. Tie;T. T. Harkins;S. Veronese;T.-L. Wang;J. D. Weingart;C. L. Wolfgang;L. D. Wood;D. Xing;R. H. Hruban;J. Wu;P. J. Allen;C. M. Schmidt;M. A. Choti;V. E. Velculescu;K. W. Kinzler;B. Vogelstein;N. Papadopoulos;L. A. Diaz | |
| Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer | 2014 | S. Misale;S. Arena;S. Lamba;G. Siravegna;A. Lallo;S. Hobor;M. Russo;M. Buscarino;L. Lazzari;A. Sartore-Bianchi;K. Bencardino;A. Amatu;C. Lauricella;E. Valtorta;S. Siena;F. Di Nicolantonio;A. Bardelli | |
| Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance. | 2014 | Siravegna G;Bardelli A | |
| Minimal residual disease in breast cancer: in blood veritas. | 2014 | Siravegna G; Bardelli A | |
| Molecular heterogeneity and receptor coamplification drive resistance to targeted therapy in MET-Amplified esophagogastric cancer | 2015 | Kwak, Eunice L.; Ahronian, Leanne G.; Siravegna, Giulia; Mussolin, Benedetta; Godfrey, Jason T.; Clark, Jeffrey W.; Blaszkowsky, Lawrence S.; Ryan, David P.; Lennerz, Jochen K.; John Iafrate, A.; Bardelli, Alberto; Hong, Theodore S.; Corcoran, Ryan B. | |
| Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients | 2015 | Siravegna, Giulia; Mussolin, Benedetta; Buscarino, Michela; Corti, Giorgio; Cassingena, Andrea; Crisafulli, Giovanni; Ponzetti, Agostino; Cremolini, Chiara; Amatu, Alessio; Lauricella, Calogero; Lamba, Simona; Hobor, Sebastijan; Avallone, Antonio; Valtorta, Emanuele; Rospo, Giuseppe; Medico, Enzo; Motta, Valentina; Antoniotti, Carlotta; Tatangelo, Fabiana; Bellosillo, Beatriz; Veronese, Silvio; Budillon, Alfredo; Montagut, Clara; Racca, Patrizia; Marsoni, Silvia; Falcone, Alfredo; Corcoran, Ryan B; Di Nicolantonio, Federica; Loupakis, Fotios; Siena, Salvatore; Sartore-Bianchi, Andrea; Bardelli, Alberto | |
| Liquid biopsies to evaluate early therapeutic response in colorectal cancer | 2015 | Montagut, C; Siravegna, G; Bardelli, A | |
| Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer | 2015 | Barault, L; Amatu, A; Bleeker, F E; Moutinho, C; Falcomatà, C; Fiano, V; Cassingena, A; Siravegna, G; Milione, M; Cassoni, P; De Braud, F; Rudà, R; Soffietti, R; Venesio, T; Bardelli, A; Wesseling, P; de Witt Hamer, P; Pietrantonio, F; Siena, S; Esteller, M; Sartore-Bianchi, A; Di Nicolantonio, F | |
| Emergence of multiple EGFR extracellular mutations during cetuximab treatment in colorectal cancer | 2015 | S. Arena; B. Bellosillo; G. Siravegna; A. Martinez; I. Canadas; L. Lazzari; N. Ferruz; M. Russo; S. Misale; I. Gonzalez; M. Iglesias; E. Gavilan; G. Corti; S. Hobor; G. Crisafulli; M. Salido; J. Sanchez; A. Dalmases; J. Bellmunt; G.D. Fabritiis; A. Rovira; F. Di Nicolantonio; J. Albanell; A. Bardelli; C. Montagut | |
| Acquired resistance to the TRK inhibitor entrectinib in colorectal cancer | 2016 | Russo, Mariangela; Misale, Sandra; Wei, Ge; Siravegna, Giulia; Crisafulli, Giovanni; Lazzari, Luca; Corti, Giorgio; Rospo, Giuseppe; Novara, Luca; Mussolin, Benedetta; Bartolini, Alice; Cam, Nicholas; Patel, Roopal; Yan, Shunqi; Shoemaker, Robert; Wild, Robert; Di Nicolantonio, Federica; Sartore-Bianchi, Andrea; Li, Gang; Siena, Salvatore; Bardelli, Alberto | |
| Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer | 2016 | Van Emburgh, Beth O; Arena, Sabrina; Siravegna, Giulia; Lazzari, Luca; Crisafulli, Giovanni; Corti, Giorgio; Mussolin, Benedetta; Baldi, Federica; Buscarino, Michela; Bartolini, Alice; Valtorta, Emanuele; Vidal, Joana; Bellosillo, Beatriz; Germano, Giovanni; Pietrantonio, Filippo; Ponzetti, Agostino; Albanell, Joan; Siena, Salvatore; Sartore-Bianchi, Andrea; Di Nicolantonio, Federica; Montagut, Clara; Bardelli, Alberto | |
| Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition | 2016 | Hata, Aaron N; Niederst, Matthew J; Archibald, Hannah L; Gomez-Caraballo, Maria; Siddiqui, Faria M; Mulvey, Hillary E; Maruvka, Yosef E; Ji, Fei; Bhang, Hyo-Eun C; Krishnamurthy Radhakrishna, Viveksagar; Siravegna, Giulia; Hu, Haichuan; Raoof, Sana; Lockerman, Elizabeth; Kalsy, Anuj; Lee, Dana; Keating, Celina L; Ruddy, David A; Damon, Leah J; Crystal, Adam S; Costa, Carlotta; Piotrowska, Zofia; Bardelli, Alberto; Iafrate, Anthony J; Sadreyev, Ruslan I; Stegmeier, Frank; Getz, Gad; Sequist, Lecia V; Faber, Anthony C; Engelman, Jeffrey A | |
| Blood circulating tumor DNA for non-invasive genotyping of colon cancer patients | 2016 | Siravegna, Giulia; Bardelli, Alberto | |
| Tumor heterogeneity and Lesion-Specific response to targeted therapy in colorectal cancer | 2016 | Russo, Mariangela; Siravegna, Giulia; Blaszkowsky, Lawrence S.; Corti, Giorgio; Crisafulli, Giovanni; Ahronian, Leanne G.; Mussolin, Benedetta; Kwak, Eunice L.; Buscarino, Michela; Lazzari, Luca; Valtorta, Emanuele; Truini, Mauro; Jessop, Nicholas A.; Robinson, Hayley E.; Hong, Theodore S.; Mino-Kenudson, Mari; Di Nicolantonio, Federica; Thabet, Ashraf; Sartore-Bianchi, Andrea; Siena, Salvatore; Iafrate, John; Bardelli, Alberto; ^*; Corcoran, Ryan B.; ^*; ^ joint co-last authorship; *joint corresponding authorship | |
| Clonal evolution and KRAS-MET coamplification during secondary resistance to EGFR-targeted therapy in metastatic colorectal cancer | 2016 | Sartore-Bianchi, Andrea; Valtorta, Emanuele; Amatu, Alessio; Veronese, Silvio; Lauricella, Calogero; Bonazzina, Erica; Siravegna, Giulia; Truini, Mauro; Bardelli, Alberto; Siena, Salvatore | |
| MET-driven resistance to dual EGFR and BRAF blockade may be overcome by switching from EGFR to MET inhibition in BRAF mutated colorectal cancer | 2016 | Pietrantonio, Filippo; Oddo, Daniele; Gloghini, Annunziata; Valtorta, Emanuele; Berenato, Rosa; Barault, Ludovic; Caporale, Marta; Busico, Adele; Morano, Federica; Gualeni, Ambra Vittoria; Alessi, Alessandra; Siravegna, Giulia; Perrone, Federica; Di Bartolomeo, Maria; Bardelli, Alberto; de Braud, Filippo; Di Nicolantonio, Federica | |
| Molecular landscape of acquired resistance to targeted therapy combinations in BRAF mutant colorectal cancer | 2016 | Oddo, D; Sennott, Em; Barault, L; Valtorta, E; Arena, S; Cassingena, A; Filiciotto, G; Marzolla, G; Elez, E; van Geel RM, ; Bartolini, A; Crisafulli, G; Boscaro, V; Godfrey, Jt; Buscarino, M; Cancelliere, C; Linnebacher, M; Corti, G; Truini, M; Siravegna, G; Grasselli, J; Gallicchio, M; Bernards, R; Schellens, Jh; Tabernero, J; Engelman, Ja; Sartore-Bianchi, A; Bardelli, A; Siena, S; Corcoran, Rb; Di Nicolantonio, F. | |
| MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations | 2016 | Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex A.; Montagut, Clara; Di Nicolantonio, Federica; Nering, Rachel; Bardelli, Alberto |
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