Sfoglia per Autore
Identification of Small Synthetic Anti-Pyroptotic Compounds
2013-01-01 G. Miglio; M. Bertinaria; M. Rogazzo; M. Cocco; D. Garella; A. Di Stilo; R. Fantozzi
Synthesis and preliminary evaluation of model compounds targeting the NLRP3 inflammasome pathways
2013-01-01 Davide Garella; Mattia Cocco; Antonella Di Stilo; Gianluca Miglio; Massimo Collino; Roberto Fantozzi; Massimo Bertinaria
Targeting NLRP3 inflammasome regulatory mechanisms: design of anti-pyroptotic compounds for autoinflammatory diseases
2014-01-01 Massimo Bertinaria; Mattia Cocco; Davide Garella; Marta Giorgis; Antonella Di Stilo; Gianluca Miglio
Design, Synthesis and Pharmacological Evaluation of Anti-Pyroptotic Compounds Acting on NLRP3 Inflammasome Signaling Pathway: a New Start for Anti-Inflammatory Drugs?
2014-01-01 Bertinaria Massimo; Cocco Mattia; Garella Davide; Marini Elisabetta; Di Stilo Antonella; Miglio Gianluca
Use of the Morita-Baylis-Hillman reaction in the design of compounds inhibiting NLRP3 inflammasome signaling pathways
2014-01-01 M. Cocco; D. Garella; G. Miglio; E. Borretto; L. Stevanato; A. Di Stilo; M. Bertinaria
Electrophilic Warhead-Based Design of Compounds Preventing NLRP3 Inflammasome-Dependent Pyroptosis
2014-01-01 Mattia Cocco; Davide Garella; Antonella Di Stilo; Emily Borretto; Livio Stevanato; Marta Giorgis; Elisabetta Marini; Roberto Fantozzi; Gianluca Miglio; Massimo Bertinaria
Synthesis of Small Molecules as Potential DNA Methylation Modulators
2015-01-01 Garella, Davide; Braschi, Alessandra Maria; Cocco, Mattia; Giorgis, Marta; Costale, Annalisa; Stilo, Antonella Di; Atlante, Sandra; Gaetano, Carlo; Bertinaria, Massimo
Is NLRP3 inflammasome a new pharmacological target in myocardial ischemia/reperfusion injury?
2015-01-01 Femminò, S; Chiazza, F; Mastrocola, R; Tullio, F; Penna, C; Nigro, D; Alloatti, G; Cocco, M; Garella, D; Bertinaria, M; Fantozzi, R; Aragno, M; Collino, M; Pagliaro, P
Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome Inhibitors
2016-01-01 Cocco, Mattia; Miglio, Gianluca; Giorgis, Marta; Garella, Davide; Marini, Elisabetta; Costale, Annalisa; Regazzoni, Luca; Vistoli, Giulio; Orioli, Marica; Massulaha-Ahmed, Raïhane; Détraz-Durieux, Isabelle; Groslambert, Marine; Py, Bénédicte F.; Bertinaria, Massimo
Design and synthesis of N-benzoyl amino acid derivatives as DNA methylation inhibitors
2016-01-01 Garella, Davide; Atlante, Sandra; Borretto, Emily; Cocco, Mattia; Giorgis, Marta; Costale, Annalisa; Stevanato, Livio; Miglio, Gianluca; Cencioni, Chiara; Fernández de Gortari, Eli; Medina Franco, José L.; Spallotta, Francesco; Gaetano, Carlo; Bertinaria, Massimo
Cardiac Epi-Metabolic Signature Revealed by Integrated Omics Approach in Diabetic Patients: Rescue by Active DNA Demethylation via TET-TDG Complex Reactivation
2016-01-01 Spallotta, F; Cencioni, C; Atlante, S; Garella, D; Cocco, M; Mori, M; Mastrocola, R; Kuenne, C; Guenther, S; Nanni, S; Azzimato, V; Zukunft, S; Kornberger, A; Di Stilo, A; Aragno, M; Martelli, F; Farsetti, A; Fleming, I; Braun, T; Beiras-Fernandez, A; Botta, B; Collino, M; Bertinaria, M; Zeiher, Am; Gaetano, C.
Targeting of NLRP3 Inflammasome With a Novel Selective Inhibitor as a Suitable Strategy for the Pharmacological Treatment of Bowel Inflammation
2016-01-01 Pellegrini C.; Fornai M.; Colucci R.; Lopez-Castejon G.; Cocco M.; Garella D.; Bertinaria M.; Blandizzi C.; Antonioli L
Pharmacological inhibition of NLRP3 inflammasome attenuates myocardial ischemia/reperfusion injury by activation of RISK and mitochondrial pathways
2016-01-01 Mastrocola, Raffaella; Penna, Claudia; Tullio, Francesca; Femminò, Saveria; Nigro, Debora; Chiazza, Fausto; Serpe, Loredana; Collotta, Debora; Alloatti, Giuseppe; Cocco, Mattia; Bertinaria, Massimo; Pagliaro, Pasquale; Aragno, Manuela; Collino, Massimo
Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease
2017-01-01 Cocco, Mattia; Pellegrini, Carolina; Martínez-Banaclocha, Helios; Giorgis, Marta; Marini, Elisabetta; Costale, Annalisa; Miglio, Gianluca; Fornai, Matteo; Antonioli, Luca; López-Castejón, Gloria; Tapia-Abellán, Ana; Angosto, Diego; Hafner-Bratkovič, Iva; Regazzoni, Luca; Blandizzi, Corrado; Pelegrín, Pablo; Bertinaria, Massimo
Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells from Type2 Diabetes Patients: Rescue by alpha Ketoglutarate and TET-TDG Functional Reactivation
2018-01-01 Spallotta, Francesco; Cencioni, Chiara; Atlante, Sandra; Garella, Davide; Cocco, Mattia; Mori, Mattia; Mastrocola, Raffaella; Kuenne, Carsten; Guenther, Stefan; Nanni, Simona; Azzimato, Valerio; Zukunft, Sven; Kornberger, Angela; Sã¼rã¼n, Duran; Schnã¼tgen, Frank; Von Melchner, Harald; Di Stilo, Antonella; Aragno, Manuela; Braspenning, Maarten; Van Criekinge, Wim; De Blasio, Miles J.; Ritchie, Rebecca H.; Zaccagnini, Germana; Martelli, Fabio; Farsetti, Antonella; Fleming, Ingrid; Braun, Thomas; Beiras-Fernandez, Andres; Botta, Bruno; Collino, Massimo; Bertinaria, Massimo; Zeiher, Andreas M.; Gaetano, Carlo
COMPOSTI INIBITORI DELL’INFLAMMASOMA NLRP3 E LORO USO
2021-01-01 BLANDIZZI CORRADO, PELLEGRINI CAROLINA, FORNAI MATTEO, ANTONIOLI LUCA, COLUCCI ROCCHINA, BERTINARIA MASSIMO, MARINI ELISABETTA, BOSCARO VALENTINA, GASTALDI SIMONE, COCCO MATTIA
NLRP3 INFLAMMASOME-inhibiting compounds and the use thereof
2022-01-01 Blandizzi Corrado, Pellegrini Carolina, Fornai Matteo, Antonioli Luca, Colucci Rocchina, Bertinaria Massimo, Marini Elisabetta, Boscaro Valentina, Gastaldi Simone, Cocco Mattia
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Identification of Small Synthetic Anti-Pyroptotic Compounds | 2013 | G. Miglio; M. Bertinaria; M. Rogazzo; M. Cocco; D. Garella; A. Di Stilo; R. Fantozzi | |
| Synthesis and preliminary evaluation of model compounds targeting the NLRP3 inflammasome pathways | 2013 | Davide Garella; Mattia Cocco; Antonella Di Stilo; Gianluca Miglio; Massimo Collino; Roberto Fantozzi; Massimo Bertinaria | |
| Targeting NLRP3 inflammasome regulatory mechanisms: design of anti-pyroptotic compounds for autoinflammatory diseases | 2014 | Massimo Bertinaria; Mattia Cocco; Davide Garella; Marta Giorgis; Antonella Di Stilo; Gianluca Miglio | |
| Design, Synthesis and Pharmacological Evaluation of Anti-Pyroptotic Compounds Acting on NLRP3 Inflammasome Signaling Pathway: a New Start for Anti-Inflammatory Drugs? | 2014 | Bertinaria Massimo; Cocco Mattia; Garella Davide; Marini Elisabetta; Di Stilo Antonella; Miglio Gianluca | |
| Use of the Morita-Baylis-Hillman reaction in the design of compounds inhibiting NLRP3 inflammasome signaling pathways | 2014 | M. Cocco; D. Garella; G. Miglio; E. Borretto; L. Stevanato; A. Di Stilo; M. Bertinaria | |
| Electrophilic Warhead-Based Design of Compounds Preventing NLRP3 Inflammasome-Dependent Pyroptosis | 2014 | Mattia Cocco; Davide Garella; Antonella Di Stilo; Emily Borretto; Livio Stevanato; Marta Giorgis; Elisabetta Marini; Roberto Fantozzi; Gianluca Miglio; Massimo Bertinaria | |
| Synthesis of Small Molecules as Potential DNA Methylation Modulators | 2015 | Garella, Davide; Braschi, Alessandra Maria; Cocco, Mattia; Giorgis, Marta; Costale, Annalisa; Stilo, Antonella Di; Atlante, Sandra; Gaetano, Carlo; Bertinaria, Massimo | |
| Is NLRP3 inflammasome a new pharmacological target in myocardial ischemia/reperfusion injury? | 2015 | Femminò, S; Chiazza, F; Mastrocola, R; Tullio, F; Penna, C; Nigro, D; Alloatti, G; Cocco, M; Garella, D; Bertinaria, M; Fantozzi, R; Aragno, M; Collino, M; Pagliaro, P | |
| Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome Inhibitors | 2016 | Cocco, Mattia; Miglio, Gianluca; Giorgis, Marta; Garella, Davide; Marini, Elisabetta; Costale, Annalisa; Regazzoni, Luca; Vistoli, Giulio; Orioli, Marica; Massulaha-Ahmed, Raïhane; Détraz-Durieux, Isabelle; Groslambert, Marine; Py, Bénédicte F.; Bertinaria, Massimo | |
| Design and synthesis of N-benzoyl amino acid derivatives as DNA methylation inhibitors | 2016 | Garella, Davide; Atlante, Sandra; Borretto, Emily; Cocco, Mattia; Giorgis, Marta; Costale, Annalisa; Stevanato, Livio; Miglio, Gianluca; Cencioni, Chiara; Fernández de Gortari, Eli; Medina Franco, José L.; Spallotta, Francesco; Gaetano, Carlo; Bertinaria, Massimo | |
| Cardiac Epi-Metabolic Signature Revealed by Integrated Omics Approach in Diabetic Patients: Rescue by Active DNA Demethylation via TET-TDG Complex Reactivation | 2016 | Spallotta, F; Cencioni, C; Atlante, S; Garella, D; Cocco, M; Mori, M; Mastrocola, R; Kuenne, C; Guenther, S; Nanni, S; Azzimato, V; Zukunft, S; Kornberger, A; Di Stilo, A; Aragno, M; Martelli, F; Farsetti, A; Fleming, I; Braun, T; Beiras-Fernandez, A; Botta, B; Collino, M; Bertinaria, M; Zeiher, Am; Gaetano, C. | |
| Targeting of NLRP3 Inflammasome With a Novel Selective Inhibitor as a Suitable Strategy for the Pharmacological Treatment of Bowel Inflammation | 2016 | Pellegrini C.; Fornai M.; Colucci R.; Lopez-Castejon G.; Cocco M.; Garella D.; Bertinaria M.; Blandizzi C.; Antonioli L | |
| Pharmacological inhibition of NLRP3 inflammasome attenuates myocardial ischemia/reperfusion injury by activation of RISK and mitochondrial pathways | 2016 | Mastrocola, Raffaella; Penna, Claudia; Tullio, Francesca; Femminò, Saveria; Nigro, Debora; Chiazza, Fausto; Serpe, Loredana; Collotta, Debora; Alloatti, Giuseppe; Cocco, Mattia; Bertinaria, Massimo; Pagliaro, Pasquale; Aragno, Manuela; Collino, Massimo | |
| Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease | 2017 | Cocco, Mattia; Pellegrini, Carolina; Martínez-Banaclocha, Helios; Giorgis, Marta; Marini, Elisabetta; Costale, Annalisa; Miglio, Gianluca; Fornai, Matteo; Antonioli, Luca; López-Castejón, Gloria; Tapia-Abellán, Ana; Angosto, Diego; Hafner-Bratkovič, Iva; Regazzoni, Luca; Blandizzi, Corrado; Pelegrín, Pablo; Bertinaria, Massimo | |
| Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells from Type2 Diabetes Patients: Rescue by alpha Ketoglutarate and TET-TDG Functional Reactivation | 2018 | Spallotta, Francesco; Cencioni, Chiara; Atlante, Sandra; Garella, Davide; Cocco, Mattia; Mori, Mattia; Mastrocola, Raffaella; Kuenne, Carsten; Guenther, Stefan; Nanni, Simona; Azzimato, Valerio; Zukunft, Sven; Kornberger, Angela; Sã¼rã¼n, Duran; Schnã¼tgen, Frank; Von Melchner, Harald; Di Stilo, Antonella; Aragno, Manuela; Braspenning, Maarten; Van Criekinge, Wim; De Blasio, Miles J.; Ritchie, Rebecca H.; Zaccagnini, Germana; Martelli, Fabio; Farsetti, Antonella; Fleming, Ingrid; Braun, Thomas; Beiras-Fernandez, Andres; Botta, Bruno; Collino, Massimo; Bertinaria, Massimo; Zeiher, Andreas M.; Gaetano, Carlo | |
| COMPOSTI INIBITORI DELL’INFLAMMASOMA NLRP3 E LORO USO | 2021 | BLANDIZZI CORRADO, PELLEGRINI CAROLINA, FORNAI MATTEO, ANTONIOLI LUCA, COLUCCI ROCCHINA, BERTINARIA MASSIMO, MARINI ELISABETTA, BOSCARO VALENTINA, GASTALDI SIMONE, COCCO MATTIA | |
| NLRP3 INFLAMMASOME-inhibiting compounds and the use thereof | 2022 | Blandizzi Corrado, Pellegrini Carolina, Fornai Matteo, Antonioli Luca, Colucci Rocchina, Bertinaria Massimo, Marini Elisabetta, Boscaro Valentina, Gastaldi Simone, Cocco Mattia |
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