Sfoglia per Autore
Circular dichroism in drug discovery and development: an abridged review
2010-01-01 Bertucci C; Pistolozzi M; De Simone A.
Structural characterization of p53 isoforms due to the polymorphism at codon 72 by Mass Spectrometry and Circular Dichroism
2010-01-01 NALDI, MARINA; PISTOLOZZI, MARCO; BERTUCCI, CARLO; DE SIMONE, ANGELA; ALTILIA, SERENA; PIERINI, MICHELA; FRANCESCHI, CLAUDIO; SALVIOLI, STEFANO; ANDRISANO, VINCENZA
Beta-secretase as a target for Alzheimer's disease drug discovery: an overview of in vitro methods for characterization of inhibitors
2011-01-01 F. Mancini; A. De Simone; V. Andrisano
Reversible human serum albumin binding of lipocrine: a circular dichroism study
2011-01-01 C. Bertucci; A. De Simone; M. Pistolozzi; M. Rosini
Structural characterization of recombinant therapeutic proteins by circular dichroism
2011-01-01 Bertucci C; Pistolozzi M; De Simone A.
Amyloid beta-Peptide 25-35 Self Assembly and Its Inhibition: A Model Undecapeptide System to Gain Atomistic and Secondary Structure Details of the Alzheimer's Disease Process and Treatment
2012-01-01 Naldi M.; Fiori J.; Pistolozzi M.; Drake A.F.; Bertucci C.; Wu R.; Mlynarczyk K.; Filipek S.; De Simone A.; Andrisano V.
Optical Biosensors and Applications to Drug Discovery and Development in Cancer Research
2012-01-01 Bertucci Carlo; De Simone Angela
Protein Flexibility in Virtual Screening: The BACE-1 Case Study
2012-01-01 Cosconati S.; Marinelli L.; Di Leva F.S.; La Pietra V.; De Simone A.; Mancini F.; Andrisano V.; Novellino E.; Goodsell D.S.; Olson A.J.
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation
2012-01-01 G. P. Chiriano; A. De Simone; F. Mancini; D. I. Perez; A. Cavalli; M. L. Bolognesi; G. Legname; A. Martinez; V. Andrisano; P. Carloni; M. Roberti
Quinones bearing non-steroidal anti-inflammatory fragments as multitarget ligands for Alzheimer’s disease
2013-01-01 Federica Prati; Manuela Bartolini; Elena Simoni; Angela De Simone; Antonella Pinto; Vincenza Andrisano; Maria Laura Bolognesi
Surface plasmon resonance, fluorescence, and circular dichroism studies for the characterization of the binding of BACE-1 inhibitors
2013-01-01 Angela De Simone; Francesca Mancini; Feliciana Real Fernàndez; Paolo Rovero; Carlo Bertucci; Vincenza Andrisano
Human recombinant beta-secretase immobilized enzyme reactor for fast hits’ selection and characterization from a virtual screening library
2013-01-01 Angela De Simone; Francesca Mancini; Sandro Cosconati; Luciana Marinelli; Valeria La Pietra; Ettore Novellino; Vincenza Andrisano
Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents
2014-01-01 Viayna E.; Sola I.; Bartolini M.; De Simone A.; Tapia-Rojas C.; Serrano F.G.; Sabaté R.; Juárez-Jiménez J.; Pérez B.; Luque F.J.; Andrisano V.; Clos M.V.; Inestrosa N.C.; Muñoz-Torrero D.
Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease
2014-01-01 Belluti F.; De Simone A.; Tarozzi A.; Bartolini M.; Djemil A.; Bisi A.; Gobbi S.; Montanari S.; Cavalli A.; Andrisano V.; Bottegoni G.; Rampa A.
Liquid chromatographic enzymatic studies with on-line Beta-secretase immobilized enzyme reactor and 4-(4-dimethylaminophenylazo) benzoic acid/5-[(2-aminoethyl) amino] naphthalene-1-sulfonic acid as fluorogenic substrate
2014-01-01 Angela De Simone; Claudia Seidl; Cid A. Santos; Vincenza Andrisano
Design, synthesis, in silico and in vitro screening of 1,2,4-thiadiazole analogues as non-peptide inhibitors of beta-secretase
2014-01-01 Gurjar AS; Andrisano V; De Simone A; Velingkar VS
From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold
2015-01-01 Angela Rampa; Francesca Mancini; Angela De Simone; Federico Falchi; Federica Belluti; Rita Maria Concetta Di Martino; Silvia Gobbi; Vincenza Andrisano; Andrea Tarozzi; Manuela Bartolini; Andrea Cavalli; Alessandra Bisi
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease
2015-01-01 Prati Federica; De Simone Angela; Armirotti Andrea; Summa Maria; Pizzirani Daniela; Scarpelli Rita; Bertozzi Sine Mandrup; Perez Daniel I.; Andrisano Vincenza; Perez-Castillo Ana; Monti Barbara; Massenzio Francesca; Polito Letizia; Racchi Marco; Sabatino Piera; Bottegoni Giovanni; Martinez Ana; Cavalli Andrea; Bolognesi Maria L.
Multitarget drug discovery for Alzheimer's disease: triazinones as BACE-1 and GSK-3β inhibitors
2015-01-01 Prati F; De Simone A; Bisignano P; Armirotti A; Summa M; Pizzirani D; Scarpelli R; Perez DI; Andrisano V; Perez-Castillo A; Monti B; Massenzio F; Polito L; Racchi M; Favia AD; Bottegoni G; Martinez A; Bolognesi ML; Cavalli A
Multifunctional activity of some isoquinoline alkaloids from Corydalis cava tubers on Alzheimer's disease targets
2016-01-01 Chlebek J; De Simone A; Pérez Di; Pérez C; Havlíková L; Hošťálková A; Opletal L; Cahlíková L; Andrisano V
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Circular dichroism in drug discovery and development: an abridged review | 2010 | Bertucci C; Pistolozzi M; De Simone A. | |
| Structural characterization of p53 isoforms due to the polymorphism at codon 72 by Mass Spectrometry and Circular Dichroism | 2010 | NALDI, MARINA; PISTOLOZZI, MARCO; BERTUCCI, CARLO; DE SIMONE, ANGELA; ALTILIA, SERENA; PIERINI, MICHELA; FRANCESCHI, CLAUDIO; SALVIOLI, STEFANO; ANDRISANO, VINCENZA | |
| Beta-secretase as a target for Alzheimer's disease drug discovery: an overview of in vitro methods for characterization of inhibitors | 2011 | F. Mancini; A. De Simone; V. Andrisano | |
| Reversible human serum albumin binding of lipocrine: a circular dichroism study | 2011 | C. Bertucci; A. De Simone; M. Pistolozzi; M. Rosini | |
| Structural characterization of recombinant therapeutic proteins by circular dichroism | 2011 | Bertucci C; Pistolozzi M; De Simone A. | |
| Amyloid beta-Peptide 25-35 Self Assembly and Its Inhibition: A Model Undecapeptide System to Gain Atomistic and Secondary Structure Details of the Alzheimer's Disease Process and Treatment | 2012 | Naldi M.; Fiori J.; Pistolozzi M.; Drake A.F.; Bertucci C.; Wu R.; Mlynarczyk K.; Filipek S.; De Simone A.; Andrisano V. | |
| Optical Biosensors and Applications to Drug Discovery and Development in Cancer Research | 2012 | Bertucci Carlo; De Simone Angela | |
| Protein Flexibility in Virtual Screening: The BACE-1 Case Study | 2012 | Cosconati S.; Marinelli L.; Di Leva F.S.; La Pietra V.; De Simone A.; Mancini F.; Andrisano V.; Novellino E.; Goodsell D.S.; Olson A.J. | |
| A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation | 2012 | G. P. Chiriano; A. De Simone; F. Mancini; D. I. Perez; A. Cavalli; M. L. Bolognesi; G. Legname; A. Martinez; V. Andrisano; P. Carloni; M. Roberti | |
| Quinones bearing non-steroidal anti-inflammatory fragments as multitarget ligands for Alzheimer’s disease | 2013 | Federica Prati; Manuela Bartolini; Elena Simoni; Angela De Simone; Antonella Pinto; Vincenza Andrisano; Maria Laura Bolognesi | |
| Surface plasmon resonance, fluorescence, and circular dichroism studies for the characterization of the binding of BACE-1 inhibitors | 2013 | Angela De Simone; Francesca Mancini; Feliciana Real Fernàndez; Paolo Rovero; Carlo Bertucci; Vincenza Andrisano | |
| Human recombinant beta-secretase immobilized enzyme reactor for fast hits’ selection and characterization from a virtual screening library | 2013 | Angela De Simone; Francesca Mancini; Sandro Cosconati; Luciana Marinelli; Valeria La Pietra; Ettore Novellino; Vincenza Andrisano | |
| Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents | 2014 | Viayna E.; Sola I.; Bartolini M.; De Simone A.; Tapia-Rojas C.; Serrano F.G.; Sabaté R.; Juárez-Jiménez J.; Pérez B.; Luque F.J.; Andrisano V.; Clos M.V.; Inestrosa N.C.; Muñoz-Torrero D. | |
| Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease | 2014 | Belluti F.; De Simone A.; Tarozzi A.; Bartolini M.; Djemil A.; Bisi A.; Gobbi S.; Montanari S.; Cavalli A.; Andrisano V.; Bottegoni G.; Rampa A. | |
| Liquid chromatographic enzymatic studies with on-line Beta-secretase immobilized enzyme reactor and 4-(4-dimethylaminophenylazo) benzoic acid/5-[(2-aminoethyl) amino] naphthalene-1-sulfonic acid as fluorogenic substrate | 2014 | Angela De Simone; Claudia Seidl; Cid A. Santos; Vincenza Andrisano | |
| Design, synthesis, in silico and in vitro screening of 1,2,4-thiadiazole analogues as non-peptide inhibitors of beta-secretase | 2014 | Gurjar AS; Andrisano V; De Simone A; Velingkar VS | |
| From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold | 2015 | Angela Rampa; Francesca Mancini; Angela De Simone; Federico Falchi; Federica Belluti; Rita Maria Concetta Di Martino; Silvia Gobbi; Vincenza Andrisano; Andrea Tarozzi; Manuela Bartolini; Andrea Cavalli; Alessandra Bisi | |
| 3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease | 2015 | Prati Federica; De Simone Angela; Armirotti Andrea; Summa Maria; Pizzirani Daniela; Scarpelli Rita; Bertozzi Sine Mandrup; Perez Daniel I.; Andrisano Vincenza; Perez-Castillo Ana; Monti Barbara; Massenzio Francesca; Polito Letizia; Racchi Marco; Sabatino Piera; Bottegoni Giovanni; Martinez Ana; Cavalli Andrea; Bolognesi Maria L. | |
| Multitarget drug discovery for Alzheimer's disease: triazinones as BACE-1 and GSK-3β inhibitors | 2015 | Prati F; De Simone A; Bisignano P; Armirotti A; Summa M; Pizzirani D; Scarpelli R; Perez DI; Andrisano V; Perez-Castillo A; Monti B; Massenzio F; Polito L; Racchi M; Favia AD; Bottegoni G; Martinez A; Bolognesi ML; Cavalli A | |
| Multifunctional activity of some isoquinoline alkaloids from Corydalis cava tubers on Alzheimer's disease targets | 2016 | Chlebek J; De Simone A; Pérez Di; Pérez C; Havlíková L; Hošťálková A; Opletal L; Cahlíková L; Andrisano V |
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