Sfoglia per Autore
DegraderTCM: A Computationally Sparing Approach for Predicting Ternary Degradation Complexes
2024-01-01 Rossetti P.; Apprato G.; Caron G.; Ermondi G.; Rossi Sebastiano M.
Exploring the chemical space of orally bioavailable PROTACs
2024-01-01 Apprato G.; Poongavanam V.; Garcia Jimenez D.; Atilaw Y.; Erdelyi M.; Ermondi G.; Caron G.; Kihlberg J.
Conformational Sampling Deciphers the Chameleonic Properties of a VHL-Based Degrader
2023-01-01 Ermondi, Giuseppe; Jimenez, Diego Garcia; Rossi Sebastiano, Matteo; Kihlberg, Jan; Caron, Giulia
In Silico Tools to Extract the Drug Design Information Content of Degradation Data: The Case of PROTACs Targeting the Androgen Receptor
2023-01-01 Apprato Giulia; D’Agostini Giulia; Rossetti Paolo; Ermondi Giuseppe; Caron Giulia
The Quest for Oral PROTAC drugs: Evaluating the Weaknesses of the Screening Pipeline
2023-01-01 Apprato, Giulia; Ermondi, Giuseppe; Caron, Giulia
Chamelogk: A Chromatographic Chameleonicity Quantifier to Design Orally Bioavailable Beyond-Rule-of-5 Drugs
2023-01-01 GARCÍA JIMÉNEZ DIEGO; Vallaro Maura; Rossi Sebastiano Matteo; Apprato Giulia; D'Agostini Giulia; Rossetti Paolo; Ermondi Giuseppe; Caron Giulia
Deleterious, protein-altering variants in the transcriptional coregulator ZMYM3 in 27 individuals with a neurodevelopmental delay phenotype
2023-01-01 Hiatt, Susan M; Trajkova, Slavica; Sebastiano, Matteo Rossi; Partridge, E Christopher; Abidi, Fatima E; Anderson, Ashlyn; Ansar, Muhammad; Antonarakis, Stylianos E; Azadi, Azadeh; Bachmann-Gagescu, Ruxandra; Bartuli, Andrea; Benech, Caroline; Berkowitz, Jennifer L; Betti, Michael J; Brusco, Alfredo; Cannon, Ashley; Caron, Giulia; Chen, Yanmin; Cochran, Meagan E; Coleman, Tanner F; Crenshaw, Molly M; Cuisset, Laurence; Curry, Cynthia J; Darvish, Hossein; Demirdas, Serwet; Descartes, Maria; Douglas, Jessica; Dyment, David A; Elloumi, Houda Zghal; Ermondi, Giuseppe; Faoucher, Marie; Farrow, Emily G; Felker, Stephanie A; Fisher, Heather; Hurst, Anna C E; Joset, Pascal; Kelly, Melissa A; Kmoch, Stanislav; Leadem, Benjamin R; Lyons, Michael J; Macchiaiolo, Marina; Magner, Martin; Mandrile, Giorgia; Mattioli, Francesca; McEown, Megan; Meadows, Sarah K; Medne, Livija; Meeks, Naomi J L; Montgomery, Sarah; Napier, Melanie P; Natowicz, Marvin; Newberry, Kimberly M; Niceta, Marcello; Noskova, Lenka; Nowak, Catherine B; Noyes, Amanda G; Osmond, Matthew; Prijoles, Eloise J; Pugh, Jada; Pullano, Verdiana; Quélin, Chloé; Rahimi-Aliabadi, Simin; Rauch, Anita; Redon, Sylvia; Reymond, Alexandre; Schwager, Caitlin R; Sellars, Elizabeth A; Scheuerle, Angela E; Shukarova-Angelovska, Elena; Skraban, Cara; Stolerman, Elliot; Sullivan, Bonnie R; Tartaglia, Marco; Thiffault, Isabelle; Uguen, Kevin; Umaña, Luis A; van Bever, Yolande; van der Crabben, Saskia N; van Slegtenhorst, Marjon A; Waisfisz, Quinten; Washington, Camerun; Rodan, Lance H; Myers, Richard M; Cooper, Gregory M
High-throughput and reliable assessments of the ionization constant of monoprotic organic acids through an arginine based mixed mode HPLC
2023-01-01 Russo G.; Kajtazi A.; Vallaro M.; Surmont P.; Ermondi G.; Anderson S.; Grumetto L.; Caron G.; Lynen F.
Ionization and lipophilicity in nonpolar media mimicking the cell membrane interior
2023-01-01 Vallaro, Maura; Ermondi, Giuseppe; Saame, Jaan; Leito, Ivo; Caron, Giulia
Front cover: "Cystic Fibrosis Mucus Model to Design More Efficient Drug Therapies" (Molecular Pharmaceutics 02/2022)
2022-01-01 Cosmin Butnarasu, Giulia Caron, Daniela Pacheco, Paola Petrini, Sonja Visentin
Dall’intelligenza artificiale nuove prospettive per la ricerca sulle malattie rare
2022-01-01 Matteo Rossi Sebastiano; Giuseppe Ermondi; Giulia Caron; Adriana Riccomagno
AI-based protein structure databases have the potential to accelerate rare diseases research: AlphaFoldDB and the case of IAHSP/Alsin
2022-01-01 Rossi Sebastiano M.; Ermondi G.; Hadano S.; Caron G.
Personalized Treatment for Infantile Ascending Hereditary Spastic Paralysis Based on In Silico Strategies
2022-01-01 Rossi Sebastiano, Matteo; Ermondi, Giuseppe; Sato, Kai; Otomo, Asako; Hadano, Shinji; Caron, Giulia
Refinement of Computational Access to Molecular Physicochemical Properties: From Ro5 to bRo5
2022-01-01 Rossi Sebastiano, Matteo; Garcia Jimenez, Diego; Vallaro, Maura; Caron, Giulia; Ermondi, Giuseppe
Application of the anthraquinone drug rhein as an axial ligand in bifunctional Pt(IV) complexes to obtain antiproliferative agents against human glioblastoma cells
2022-01-01 Gabano, Elisabetta; Gariboldi, Marzia Bruna; Caron, Giulia; Ermondi, Giuseppe; Marras, Emanuela; Vallaro, Maura; Ravera, Mauro
Designing Soluble PROTACs: Strategies and Preliminary Guidelines
2022-01-01 Diego García Jiménez; Matteo Rossi Sebastiano; Maura Vallaro; Valentina Mileo; Daniela Pizzirani; Elisa Moretti; Giuseppe Ermondi; Giulia Caron
Characterization of the new CelerisTM Arginine column: Retentive behaviour through a combination of chemometric tools and potential in drug analysis
2021-01-01 Russo, Giacomo; Vallaro, Maura; Cappelli, Luca; Anderson, Scott; Ermondi, Giuseppe; Caron, Giulia
Managing Experimental 3D Structures in the Beyond-Rule-of-5 Chemical Space: The Case of Rifampicin
2021-01-01 Ermondi, Giuseppe; Lavore, Francesca; Vallaro, Maura; Tiana, Guido; Vasile, Francesca; Caron, Giulia
IκBα targeting promotes oxidative stress-dependent cell death
2021-01-01 Carrà, Giovanna; Ermondi, Giuseppe; Riganti, Chiara; Righi, Luisella; Caron, Giulia; Menga, Alessio; Capelletto, Enrica; Maffeo, Beatrice; Lingua, Marcello Francesco; Fusella, Federica; Volante, Marco; Taulli, Riccardo; Guerrasio, Angelo; Novello, Silvia; Brancaccio, Mara; Piazza, Rocco; Morotti, Alessandro
Pt(iv) complexes based on cyclohexanediamines and the histone deacetylase inhibitor 2-(2-propynyl)octanoic acid: synthesis, characterization, cell penetration properties and antitumor activity
2021-01-01 Gabano E.; Rangone B.; Perin E.; Caron G.; Ermondi G.; Vallaro M.; Gandin V.; Marzano C.; Barbanente A.; Margiotta N.; Ravera M.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| DegraderTCM: A Computationally Sparing Approach for Predicting Ternary Degradation Complexes | 2024 | Rossetti P.; Apprato G.; Caron G.; Ermondi G.; Rossi Sebastiano M. | |
| Exploring the chemical space of orally bioavailable PROTACs | 2024 | Apprato G.; Poongavanam V.; Garcia Jimenez D.; Atilaw Y.; Erdelyi M.; Ermondi G.; Caron G.; Kihlberg J. | |
| Conformational Sampling Deciphers the Chameleonic Properties of a VHL-Based Degrader | 2023 | Ermondi, Giuseppe; Jimenez, Diego Garcia; Rossi Sebastiano, Matteo; Kihlberg, Jan; Caron, Giulia | |
| In Silico Tools to Extract the Drug Design Information Content of Degradation Data: The Case of PROTACs Targeting the Androgen Receptor | 2023 | Apprato Giulia; D’Agostini Giulia; Rossetti Paolo; Ermondi Giuseppe; Caron Giulia | |
| The Quest for Oral PROTAC drugs: Evaluating the Weaknesses of the Screening Pipeline | 2023 | Apprato, Giulia; Ermondi, Giuseppe; Caron, Giulia | |
| Chamelogk: A Chromatographic Chameleonicity Quantifier to Design Orally Bioavailable Beyond-Rule-of-5 Drugs | 2023 | GARCÍA JIMÉNEZ DIEGO; Vallaro Maura; Rossi Sebastiano Matteo; Apprato Giulia; D'Agostini Giulia; Rossetti Paolo; Ermondi Giuseppe; Caron Giulia | |
| Deleterious, protein-altering variants in the transcriptional coregulator ZMYM3 in 27 individuals with a neurodevelopmental delay phenotype | 2023 | Hiatt, Susan M; Trajkova, Slavica; Sebastiano, Matteo Rossi; Partridge, E Christopher; Abidi, Fatima E; Anderson, Ashlyn; Ansar, Muhammad; Antonarakis, Stylianos E; Azadi, Azadeh; Bachmann-Gagescu, Ruxandra; Bartuli, Andrea; Benech, Caroline; Berkowitz, Jennifer L; Betti, Michael J; Brusco, Alfredo; Cannon, Ashley; Caron, Giulia; Chen, Yanmin; Cochran, Meagan E; Coleman, Tanner F; Crenshaw, Molly M; Cuisset, Laurence; Curry, Cynthia J; Darvish, Hossein; Demirdas, Serwet; Descartes, Maria; Douglas, Jessica; Dyment, David A; Elloumi, Houda Zghal; Ermondi, Giuseppe; Faoucher, Marie; Farrow, Emily G; Felker, Stephanie A; Fisher, Heather; Hurst, Anna C E; Joset, Pascal; Kelly, Melissa A; Kmoch, Stanislav; Leadem, Benjamin R; Lyons, Michael J; Macchiaiolo, Marina; Magner, Martin; Mandrile, Giorgia; Mattioli, Francesca; McEown, Megan; Meadows, Sarah K; Medne, Livija; Meeks, Naomi J L; Montgomery, Sarah; Napier, Melanie P; Natowicz, Marvin; Newberry, Kimberly M; Niceta, Marcello; Noskova, Lenka; Nowak, Catherine B; Noyes, Amanda G; Osmond, Matthew; Prijoles, Eloise J; Pugh, Jada; Pullano, Verdiana; Quélin, Chloé; Rahimi-Aliabadi, Simin; Rauch, Anita; Redon, Sylvia; Reymond, Alexandre; Schwager, Caitlin R; Sellars, Elizabeth A; Scheuerle, Angela E; Shukarova-Angelovska, Elena; Skraban, Cara; Stolerman, Elliot; Sullivan, Bonnie R; Tartaglia, Marco; Thiffault, Isabelle; Uguen, Kevin; Umaña, Luis A; van Bever, Yolande; van der Crabben, Saskia N; van Slegtenhorst, Marjon A; Waisfisz, Quinten; Washington, Camerun; Rodan, Lance H; Myers, Richard M; Cooper, Gregory M | |
| High-throughput and reliable assessments of the ionization constant of monoprotic organic acids through an arginine based mixed mode HPLC | 2023 | Russo G.; Kajtazi A.; Vallaro M.; Surmont P.; Ermondi G.; Anderson S.; Grumetto L.; Caron G.; Lynen F. | |
| Ionization and lipophilicity in nonpolar media mimicking the cell membrane interior | 2023 | Vallaro, Maura; Ermondi, Giuseppe; Saame, Jaan; Leito, Ivo; Caron, Giulia | |
| Front cover: "Cystic Fibrosis Mucus Model to Design More Efficient Drug Therapies" (Molecular Pharmaceutics 02/2022) | 2022 | Cosmin Butnarasu, Giulia Caron, Daniela Pacheco, Paola Petrini, Sonja Visentin | |
| Dall’intelligenza artificiale nuove prospettive per la ricerca sulle malattie rare | 2022 | Matteo Rossi Sebastiano; Giuseppe Ermondi; Giulia Caron; Adriana Riccomagno | |
| AI-based protein structure databases have the potential to accelerate rare diseases research: AlphaFoldDB and the case of IAHSP/Alsin | 2022 | Rossi Sebastiano M.; Ermondi G.; Hadano S.; Caron G. | |
| Personalized Treatment for Infantile Ascending Hereditary Spastic Paralysis Based on In Silico Strategies | 2022 | Rossi Sebastiano, Matteo; Ermondi, Giuseppe; Sato, Kai; Otomo, Asako; Hadano, Shinji; Caron, Giulia | |
| Refinement of Computational Access to Molecular Physicochemical Properties: From Ro5 to bRo5 | 2022 | Rossi Sebastiano, Matteo; Garcia Jimenez, Diego; Vallaro, Maura; Caron, Giulia; Ermondi, Giuseppe | |
| Application of the anthraquinone drug rhein as an axial ligand in bifunctional Pt(IV) complexes to obtain antiproliferative agents against human glioblastoma cells | 2022 | Gabano, Elisabetta; Gariboldi, Marzia Bruna; Caron, Giulia; Ermondi, Giuseppe; Marras, Emanuela; Vallaro, Maura; Ravera, Mauro | |
| Designing Soluble PROTACs: Strategies and Preliminary Guidelines | 2022 | Diego García Jiménez; Matteo Rossi Sebastiano; Maura Vallaro; Valentina Mileo; Daniela Pizzirani; Elisa Moretti; Giuseppe Ermondi; Giulia Caron | |
| Characterization of the new CelerisTM Arginine column: Retentive behaviour through a combination of chemometric tools and potential in drug analysis | 2021 | Russo, Giacomo; Vallaro, Maura; Cappelli, Luca; Anderson, Scott; Ermondi, Giuseppe; Caron, Giulia | |
| Managing Experimental 3D Structures in the Beyond-Rule-of-5 Chemical Space: The Case of Rifampicin | 2021 | Ermondi, Giuseppe; Lavore, Francesca; Vallaro, Maura; Tiana, Guido; Vasile, Francesca; Caron, Giulia | |
| IκBα targeting promotes oxidative stress-dependent cell death | 2021 | Carrà, Giovanna; Ermondi, Giuseppe; Riganti, Chiara; Righi, Luisella; Caron, Giulia; Menga, Alessio; Capelletto, Enrica; Maffeo, Beatrice; Lingua, Marcello Francesco; Fusella, Federica; Volante, Marco; Taulli, Riccardo; Guerrasio, Angelo; Novello, Silvia; Brancaccio, Mara; Piazza, Rocco; Morotti, Alessandro | |
| Pt(iv) complexes based on cyclohexanediamines and the histone deacetylase inhibitor 2-(2-propynyl)octanoic acid: synthesis, characterization, cell penetration properties and antitumor activity | 2021 | Gabano E.; Rangone B.; Perin E.; Caron G.; Ermondi G.; Vallaro M.; Gandin V.; Marzano C.; Barbanente A.; Margiotta N.; Ravera M. |
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