Sfoglia per Autore
EVALUATION OF DRUG RESPONSES IN NON-TRANSFORMED CELLS CARRYING CANCER ALLELES
2009-01-01 Gallicchio M; Di Nicolantonio F; Arena S.; Zecchin D; Martini M; Flonta S; Stella G; Lamba S; Cancelliere C; Russo M; Geuna M; Appendino G; Fantozzi R; Medico E; Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets
2015-01-01 Medico, E; Russo, M; Picco, G; Cancelliere, C; Valtorta, E; Corti, G; Buscarino, M; Isella, C; Lamba, S; Martinoglio, B; Veronese, S; Siena, S; Sartore-Bianchi, A; Beccuti, M; Mottolese, M; Linnebacher, M; Cordero, F; Di Nicolantonio, F*; Bardelli, A*; (*co-last and *corresponding authors)
Molecular landscape of acquired resistance to targeted therapy combinations in BRAF mutant colorectal cancer
2016-01-01 Oddo, D; Sennott, Em; Barault, L; Valtorta, E; Arena, S; Cassingena, A; Filiciotto, G; Marzolla, G; Elez, E; van Geel RM, ; Bartolini, A; Crisafulli, G; Boscaro, V; Godfrey, Jt; Buscarino, M; Cancelliere, C; Linnebacher, M; Corti, G; Truini, M; Siravegna, G; Grasselli, J; Gallicchio, M; Bernards, R; Schellens, Jh; Tabernero, J; Engelman, Ja; Sartore-Bianchi, A; Bardelli, A; Siena, S; Corcoran, Rb; Di Nicolantonio, F.
The heme exporter FLVCR1A modulates cellular redox status and mitochondrial metabolism: implication in colorectal cancer
2017-01-01 Fiorito Veronica, Destefanis Francesca, Marchi Saverio, Medico Enzo, Cancelliere Carlotta, Bardelli Alberto, Silengo Lorenzo, Altruda Fiorella, Pinton Paolo, Tolosano Emanuela
The heme exporter FLVCR1a modulates the tricarboxylic acid cycle: a new target in colorectal cancer
2018-01-01 Fiorito V; Destefanis F; Marchi S; Gazzano E; Audrito V; Medico E; Cancelliere C; Chiabrando D; Petrillo S; Bardelli A; Deaglio S; Altruda F; Riganti C; Pinton P; Tolosano E
Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer
2018-01-01 Barault, L; Amatu, A; Siravegna, G; Ponzetti, A; Moran, S; Cassingena, A; Mussolin, B; Falcomatà, C; Binder, Am; Cristiano, C; Oddo, D; Guarrera, S; Cancelliere, C; Bustreo, S; Bencardino, K; Maden, S; Vanzati, A; Zavattari, P; Matullo, G; Truini, M; Grady, Wm; Racca, P; Michels, Kb; Siena, S; Esteller, M; Bardelli, A; Sartore-Bianchi, A; Di Nicolantonio, F.
Loss of the heme exporter FLVCR1a impairs mitochondrial functionality: a new approach against colorectal cancer
2018-01-01 Fiorito Veronica, Destefanis Francesca, Marchi Saverio, Audrito Valentina, Medico Enzo, Cancelliere Carlotta, Bardelli Alberto, Deaglio Silvia, Altruda Fiorella, Pinton Paolo, Tolosano Emanuela
Metabolic adaptation in colorectal cancer: heme export is required for the down-modulation of the tricarboxylic acid cycle.
2019-01-01 Fiorito V; Destefanis F; Marchi S; Gazzano E; Torretta S; Audrito V; Provero P; Medico E; Chiabrando D; Petrillo S; Porporato P; Cancelliere C; Bardelli A; Trusolino L; Deaglio S; Altruda F; Riganti C; Cardaci S; Pinton P; Tolosano E
Patient-derived xenografts and matched cell lines identify pharmacogenomic vulnerabilities in colorectal cancer
2019-01-01 Lazzari L.; Corti G.; Picco G.; Isella C.; Montone M.; Arcella P.; Durinikova E.; Zanella E.R.; Novara L.; Barbosa F.; Cassingena A.; Cancelliere C.; Medico E.; Sartore-Bianchi A.; Siena S.; Garnett M.J.; Bertotti A.; Trusolino L.; Di Nicolantonio F.; Linnebacher M.; Bardelli A.; Arena S.
Metabolic adaptation in colorectal cancer: heme export is required for the modulation of the tricarboxylic acid cycle.
2019-01-01 Fiorito V; Destefanis F; Marchi S; Gazzano E; Torretta S; Audrito V; Provero P; Medico E; Chiabrando D; Petrillo S; Porporato P; Cancelliere C; Bardelli A; Trusolino L; Deaglio S; Altruda F; Riganti C; Cardaci S; Pinton P; Tolosano E
The heme biosynthesis-heme export axis is required for the modulation of the tricarboxylic acid cycle
2019-01-01 Veronica Fiorito, F. Destefanis, S. Marchi, E. Gazzano, S. Torretta, V. Audrito, P. Provero, E. Medico, D. Chiabrando, S. Petrillo, P. E. Porporato, C. Cancelliere, A. Bardelli, L. Trusolino, S. Deaglio, F. Altruda, C. Riganti, S. Cardaci, P. Pinton, E. Tolosano.
Metabolic adaptation in colorectal cancer: heme export is required for the down-modulation of the tricarboxylic acid cycle
2019-01-01 Veronica Fiorito, F. Destefanis, S. Marchi, E. Gazzano, S. Torretta, V. Audrito, P. Provero, E. Medico, D. Chiabrando, S. Petrillo, P. E. Porporato, C. Cancelliere, A. Bardelli, L. Trusolino, S. Deaglio, F. Altruda, C. Riganti, S. Cardaci, P. Pinton, E. Tolosano.
Temozolomide drives mismatch repair deficiency and fosters neoantigen generation in tumor cells
2019-01-01 Amodio, V; Grmano, G; Barault, L; Lamba, S; Rospo, G; Magri, A; Maione, F; Crisafulli, G; Cancelliere, C; Lerda, G; Bartolini, A; Siravegna, G; Mussolin, B; Frappolli, R; Montone, M; Randon, G; de Braud, F; Angelozzi, NA; Marsoni, S; D'Incalci, M; Orlandi, A; Giraudo, E; Satore-Bianchi, A; Siena, S; Pietrantonio, F; Di Nicolantonio, F; Bardelli, A
EGFR blockade reverts resistance to KRAS G12C inhibition in colorectal cancer
2020-01-01 Amodio, Vito; Yaeger, Rona; Arcella, Pamela; Cancelliere, Carlotta; Lamba, Simona; Lorenzato, Annalisa; Arena, Sabrina; Montone, Monica; Mussolin, Benedetta; Bian, Yu; Whaley, Adele; Pinnelli, Marika; Murciano-Goroff, Yonina R; Vakiani, Efsevia; Valeri, Nicola; Liao, Wei-Li; Bhalkikar, Anuja; Thyparambil, Sheeno; Zhao, Hui-Yong; de Stanchina, Elisa; Marsoni, Silvia; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Li, Bob T; Rosen, Neal; Di Nicolantonio, Federica; Bardelli, Alberto; Misale, Sandra
The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation
2021-01-01 Fiorito V.; Allocco A.L.; Petrillo S.; Gazzano E.; Torretta S.; Marchi S.; Destefanis F.; Pacelli C.; Audrito V.; Provero P.; Medico E.; Chiabrando D.; Porporato P.E.; Cancelliere C.; Bardelli A.; Trusolino L.; Capitanio N.; Deaglio S.; Altruda F.; Pinton P.; Cardaci S.; Riganti C.; Tolosano E.
Werner helicase is a synthetic-lethal vulnerability in Mismatch Repair-Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy and Immunotherapy
2021-01-01 Picco, Gabriele; Cattaneo, Chiara Maria; van Vliet, Esmee J; Crisafulli, Giovanni; Rospo, Giuseppe; Consonni, Sarah; Vieira, Sara Filipa; Sanchez Rodriguez, Inigo; Cancelliere, Carlotta; Banerjee, Ruby; Schipper, Luuk Johan; Oddo, Daniele; Dijkstra, Krijn Kristian; Cinatl, Jindrich; Michaelis, Martin; Yang, Fengtang; Uk Group, Cell Model Network; Di Nicolantonio, Federica; Sartore-Bianchi, Andrea; Siena, Salvatore; Arena, Sabrina; Voest, Emile E; Bardelli, Alberto; Garnett, Mathew J
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| EVALUATION OF DRUG RESPONSES IN NON-TRANSFORMED CELLS CARRYING CANCER ALLELES | 2009 | Gallicchio M; Di Nicolantonio F; Arena S.; Zecchin D; Martini M; Flonta S; Stella G; Lamba S; Cancelliere C; Russo M; Geuna M; Appendino G; Fantozzi R; Medico E; Bardelli A. | |
| The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets | 2015 | Medico, E; Russo, M; Picco, G; Cancelliere, C; Valtorta, E; Corti, G; Buscarino, M; Isella, C; Lamba, S; Martinoglio, B; Veronese, S; Siena, S; Sartore-Bianchi, A; Beccuti, M; Mottolese, M; Linnebacher, M; Cordero, F; Di Nicolantonio, F*; Bardelli, A*; (*co-last and *corresponding authors) | |
| Molecular landscape of acquired resistance to targeted therapy combinations in BRAF mutant colorectal cancer | 2016 | Oddo, D; Sennott, Em; Barault, L; Valtorta, E; Arena, S; Cassingena, A; Filiciotto, G; Marzolla, G; Elez, E; van Geel RM, ; Bartolini, A; Crisafulli, G; Boscaro, V; Godfrey, Jt; Buscarino, M; Cancelliere, C; Linnebacher, M; Corti, G; Truini, M; Siravegna, G; Grasselli, J; Gallicchio, M; Bernards, R; Schellens, Jh; Tabernero, J; Engelman, Ja; Sartore-Bianchi, A; Bardelli, A; Siena, S; Corcoran, Rb; Di Nicolantonio, F. | |
| The heme exporter FLVCR1A modulates cellular redox status and mitochondrial metabolism: implication in colorectal cancer | 2017 | Fiorito Veronica, Destefanis Francesca, Marchi Saverio, Medico Enzo, Cancelliere Carlotta, Bardelli Alberto, Silengo Lorenzo, Altruda Fiorella, Pinton Paolo, Tolosano Emanuela | |
| The heme exporter FLVCR1a modulates the tricarboxylic acid cycle: a new target in colorectal cancer | 2018 | Fiorito V; Destefanis F; Marchi S; Gazzano E; Audrito V; Medico E; Cancelliere C; Chiabrando D; Petrillo S; Bardelli A; Deaglio S; Altruda F; Riganti C; Pinton P; Tolosano E | |
| Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer | 2018 | Barault, L; Amatu, A; Siravegna, G; Ponzetti, A; Moran, S; Cassingena, A; Mussolin, B; Falcomatà, C; Binder, Am; Cristiano, C; Oddo, D; Guarrera, S; Cancelliere, C; Bustreo, S; Bencardino, K; Maden, S; Vanzati, A; Zavattari, P; Matullo, G; Truini, M; Grady, Wm; Racca, P; Michels, Kb; Siena, S; Esteller, M; Bardelli, A; Sartore-Bianchi, A; Di Nicolantonio, F. | |
| Loss of the heme exporter FLVCR1a impairs mitochondrial functionality: a new approach against colorectal cancer | 2018 | Fiorito Veronica, Destefanis Francesca, Marchi Saverio, Audrito Valentina, Medico Enzo, Cancelliere Carlotta, Bardelli Alberto, Deaglio Silvia, Altruda Fiorella, Pinton Paolo, Tolosano Emanuela | |
| Metabolic adaptation in colorectal cancer: heme export is required for the down-modulation of the tricarboxylic acid cycle. | 2019 | Fiorito V; Destefanis F; Marchi S; Gazzano E; Torretta S; Audrito V; Provero P; Medico E; Chiabrando D; Petrillo S; Porporato P; Cancelliere C; Bardelli A; Trusolino L; Deaglio S; Altruda F; Riganti C; Cardaci S; Pinton P; Tolosano E | |
| Patient-derived xenografts and matched cell lines identify pharmacogenomic vulnerabilities in colorectal cancer | 2019 | Lazzari L.; Corti G.; Picco G.; Isella C.; Montone M.; Arcella P.; Durinikova E.; Zanella E.R.; Novara L.; Barbosa F.; Cassingena A.; Cancelliere C.; Medico E.; Sartore-Bianchi A.; Siena S.; Garnett M.J.; Bertotti A.; Trusolino L.; Di Nicolantonio F.; Linnebacher M.; Bardelli A.; Arena S. | |
| Metabolic adaptation in colorectal cancer: heme export is required for the modulation of the tricarboxylic acid cycle. | 2019 | Fiorito V; Destefanis F; Marchi S; Gazzano E; Torretta S; Audrito V; Provero P; Medico E; Chiabrando D; Petrillo S; Porporato P; Cancelliere C; Bardelli A; Trusolino L; Deaglio S; Altruda F; Riganti C; Cardaci S; Pinton P; Tolosano E | |
| The heme biosynthesis-heme export axis is required for the modulation of the tricarboxylic acid cycle | 2019 | Veronica Fiorito, F. Destefanis, S. Marchi, E. Gazzano, S. Torretta, V. Audrito, P. Provero, E. Medico, D. Chiabrando, S. Petrillo, P. E. Porporato, C. Cancelliere, A. Bardelli, L. Trusolino, S. Deaglio, F. Altruda, C. Riganti, S. Cardaci, P. Pinton, E. Tolosano. | |
| Metabolic adaptation in colorectal cancer: heme export is required for the down-modulation of the tricarboxylic acid cycle | 2019 | Veronica Fiorito, F. Destefanis, S. Marchi, E. Gazzano, S. Torretta, V. Audrito, P. Provero, E. Medico, D. Chiabrando, S. Petrillo, P. E. Porporato, C. Cancelliere, A. Bardelli, L. Trusolino, S. Deaglio, F. Altruda, C. Riganti, S. Cardaci, P. Pinton, E. Tolosano. | |
| Temozolomide drives mismatch repair deficiency and fosters neoantigen generation in tumor cells | 2019 | Amodio, V; Grmano, G; Barault, L; Lamba, S; Rospo, G; Magri, A; Maione, F; Crisafulli, G; Cancelliere, C; Lerda, G; Bartolini, A; Siravegna, G; Mussolin, B; Frappolli, R; Montone, M; Randon, G; de Braud, F; Angelozzi, NA; Marsoni, S; D'Incalci, M; Orlandi, A; Giraudo, E; Satore-Bianchi, A; Siena, S; Pietrantonio, F; Di Nicolantonio, F; Bardelli, A | |
| EGFR blockade reverts resistance to KRAS G12C inhibition in colorectal cancer | 2020 | Amodio, Vito; Yaeger, Rona; Arcella, Pamela; Cancelliere, Carlotta; Lamba, Simona; Lorenzato, Annalisa; Arena, Sabrina; Montone, Monica; Mussolin, Benedetta; Bian, Yu; Whaley, Adele; Pinnelli, Marika; Murciano-Goroff, Yonina R; Vakiani, Efsevia; Valeri, Nicola; Liao, Wei-Li; Bhalkikar, Anuja; Thyparambil, Sheeno; Zhao, Hui-Yong; de Stanchina, Elisa; Marsoni, Silvia; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Li, Bob T; Rosen, Neal; Di Nicolantonio, Federica; Bardelli, Alberto; Misale, Sandra | |
| The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation | 2021 | Fiorito V.; Allocco A.L.; Petrillo S.; Gazzano E.; Torretta S.; Marchi S.; Destefanis F.; Pacelli C.; Audrito V.; Provero P.; Medico E.; Chiabrando D.; Porporato P.E.; Cancelliere C.; Bardelli A.; Trusolino L.; Capitanio N.; Deaglio S.; Altruda F.; Pinton P.; Cardaci S.; Riganti C.; Tolosano E. | |
| Werner helicase is a synthetic-lethal vulnerability in Mismatch Repair-Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy and Immunotherapy | 2021 | Picco, Gabriele; Cattaneo, Chiara Maria; van Vliet, Esmee J; Crisafulli, Giovanni; Rospo, Giuseppe; Consonni, Sarah; Vieira, Sara Filipa; Sanchez Rodriguez, Inigo; Cancelliere, Carlotta; Banerjee, Ruby; Schipper, Luuk Johan; Oddo, Daniele; Dijkstra, Krijn Kristian; Cinatl, Jindrich; Michaelis, Martin; Yang, Fengtang; Uk Group, Cell Model Network; Di Nicolantonio, Federica; Sartore-Bianchi, Andrea; Siena, Salvatore; Arena, Sabrina; Voest, Emile E; Bardelli, Alberto; Garnett, Mathew J |
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