Sfoglia per Autore
Comprehensive genomic profiling on metastatic Melanoma: results from a network screening from 7 Italian Cancer Centres
2024-01-01 Pallocca, Matteo; Molineris, Ivan; Berrino, Enrico; Marcozzi, Benedetta; Betti, Martina; Levati, Lauretta; D'Atri, Stefania; Menin, Chiara; Madonna, Gabriele; Ghiorzo, Paola; Bulgarelli, Jenny; Ferraresi, Virgina; Venesio, Tiziana; Rodolfo, Monica; Rivoltini, Licia; Lanfrancone, Luisa; Ascierto, Paolo Antonio; Mazzarella, Luca; Pelicci, Pier Giuseppe; De Maria, Ruggero; Ciliberto, Gennaro; Medico, Enzo; Russo, Giandomenico
Preclinical efficacy of a HER2 synNotch/CEA-CAR combinatorial immunotherapy against colorectal cancer with HER2 amplification
2024-01-01 Cortese, Marco; Torchiaro, Erica; D'Andrea, Alice; Petti, Consalvo; Invrea, Federica; Franco, Letizia; Donini, Chiara; Leuci, Valeria; Leto, Simonetta Maria; Vurchio, Valentina; Cottino, Francesca; Isella, Claudio; Arena, Sabrina; Vigna, Elisa; Bertotti, Andrea; Trusolino, Livio; Sangiolo, Dario; Medico, Enzo
Abstract 3998: Preclinical efficacy of a synthetic Notch-based combinatorial immunotherapy against colorectal cancer with HER2 amplification
2024-01-01 Cortese, Marco; Torchiaro, Erica; D'Andrea, Alice; Petti, Consalvo; Invrea, Federica; Franco, Letizia; Donini, Chiara; Leuci, Valeria; Leto, Simonetta M.; Vurchio, Valentina; Cottino, Francesca; Isella, Claudio; Arena, Sabrina; Vigna, Elisa; Bertotti, Andrea; Trusolino, Livio; Sangiolo, Dario; Medico, Enzo
Multi-label transcriptional classification of colorectal cancer reflects tumor cell population heterogeneity
2023-01-01 Cascianelli, Silvia; Barbera, Chiara; Ulla, Alexandra Ambra; Grassi, Elena; Lupo, Barbara; Pasini, Diego; Bertotti, Andrea; Trusolino, Livio; Medico, Enzo; Isella, Claudio; Masseroli, Marco
Dual VEGFA/BRAF targeting boosts PD-1 blockade in melanoma through GM-CSF-mediated infiltration of M1 macrophages
2023-01-01 Comunanza, Valentina; Gigliotti, Chiara; Lamba, Simona; Doronzo, Gabriella; Vallariello, Edoardo; Martin, Valentina; Isella, Claudio; Medico, Enzo; Bardelli, Alberto; Sangiolo, Dario; Di Nicolantonio, Federica; Bussolino, Federico
Case report: Preclinical efficacy of NEDD8 and proteasome inhibitors in patient-derived models of signet ring high-grade mucinous colorectal cancer from a Lynch syndrome patient
2023-01-01 Torchiaro, Erica; Petti, Consalvo; Arena, Sabrina; Sassi, Francesco; Migliardi, Giorgia; Mellano, Alfredo; Porporato, Roberta; Basiricò, Marco; Gammaitoni, Loretta; Berrino, Enrico; Montone, Monica; Corti, Giorgio; Crisafulli, Giovanni; Marchio', Caterina; Bardelli, Alberto; Medico, Enzo
213 Design, characterization and preclinical validation of a combinatorial CAR-based immunotherapy against colorectal cancer with HER2 amplification
2022-01-01 Cortese, Marco; Torchiaro, Erica; Leto, Simonetta; Petti, Consalvo; D'Andrea, Alice; Degree, Master; Invrea, Federica; Arena, Sabrina; Medico, Enzo
The EurOPDX Data Portal: an open platform for patient-derived cancer xenograft data sharing and visualization
2022-01-01 Dudová, Zdenka; Conte, Nathalie; Mason, Jeremy; Stuchlík, Dalibor; Peša, Radim; Halmagyi, Csaba; Perova, Zinaida; Mosaku, Abayomi; Thorne, Ross; Follette, Alex; Pivarč, Ľuboslav; Šašinka, Radim; Usman, Muhammad; Neuhauser, Steven; Begley, Dale A; Krupke, Debra M; Frassà, Massimiliano; Fiori, Alessandro; Corsi, Riccardo; Vezzadini, Luca; Isella, Claudio; Bertotti, Andrea; Bult, Carol; Parkinson, Helen; Medico, Enzo; Meehan, Terrence; Křenek, Aleš
The neuronal protein Neuroligin 1 promotes colorectal cancer progression by modulating the APC/β-catenin pathway
2022-01-01 Pergolizzi M, Bizzozero L, Maione F, Maldi E, Isella C, Macagno M, Mariella E, Bardelli A, Medico E, Marchio Caterina, Serini G, Di Nicolantonio F, Bussolino F, Arese M
Mek inhibition in a newborn with raf1-associated noonan syndrome ameliorates hypertrophic cardiomyopathy but is insufficient to revert pulmonary vascular disease
2022-01-01 Mussa A.; Carli D.; Giorgio E.; Villar A.M.; Cardaropoli S.; Carbonara C.; Campagnoli M.F.; Galletto P.; Palumbo M.; Olivieri S.; Isella C.; Andelfinger G.; Tartaglia M.; Botta G.; Brusco A.; Medico E.; Ferrero G.B.
Successful treatment with MEK-inhibitor in a patient with NRAS-related cutaneous skeletal hypophosphatemia syndrome
2022-01-01 Carli, Diana; Cardaropoli, Simona; Tessaris, Daniele; Coppo, Paola; La Selva, Roberta; Cesario, Claudia; Lepri, Francesca Romana; Pullano, Verdiana; Palumbo, Martina; Ramenghi, Ugo; Brusco, Alfredo; Medico, Enzo; De Sanctis, Luisa; Ferrero, Giovanni Battista; Mussa, Alessandro
A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine
2022-01-01 Sebastian, Carlos; Ferrer, Christina; Serra, Maria; Choi, Jee-Eun; Ducano, Nadia; Mira, Alessia; Shah, Manasvi S; Stopka, Sylwia A; Perciaccante, Andrew J; Isella, Claudio; Moya-Rull, Daniel; Vara-Messler, Marianela; Giordano, Silvia; Maldi, Elena; Desai, Niyati; Capen, Diane E; Medico, Enzo; Cetinbas, Murat; Sadreyev, Ruslan I; Brown, Dennis; Rivera, Miguel N; Sapino, Anna; Breault, David T; Agar, Nathalie Y R; Mostoslavsky, Raul
The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation
2021-01-01 Fiorito V.; Allocco A.L.; Petrillo S.; Gazzano E.; Torretta S.; Marchi S.; Destefanis F.; Pacelli C.; Audrito V.; Provero P.; Medico E.; Chiabrando D.; Porporato P.E.; Cancelliere C.; Bardelli A.; Trusolino L.; Capitanio N.; Deaglio S.; Altruda F.; Pinton P.; Cardaci S.; Riganti C.; Tolosano E.
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
2021-01-01 Woo, Xing Yi; Giordano, Jessica; Srivastava, Anuj; Zhao, Zi-Ming; Lloyd, Michael W.; de Bruijn, Roebi; Suh, Yun-Suhk; Patidar, Rajesh; Chen, Li; Scherer, Sandra; Bailey, Matthew H.; Yang, Chieh-Hsiang; Cortes-Sanchez, Emilio; Xi, Yuanxin; Wang, Jing; Wickramasinghe, Jayamanna; Kossenkov, Andrew V.; Rebecca, Vito W.; Sun, Hua; Mashl, R. Jay; Davies, Sherri R.; Jeon, Ryan; Frech, Christian; Randjelovic, Jelena; Rosains, Jacqueline; Galimi, Francesco; Bertotti, Andrea; Lafferty, Adam; O’Farrell, Alice C.; Modave, Elodie; Lambrechts, Diether; ter Brugge, Petra; Serra, Violeta; Marangoni, Elisabetta; El Botty, Rania; Kim, Hyunsoo; Kim, Jong-Il; Yang, Han-Kwang; Lee, Charles; Dean, Dennis A.; Davis-Dusenbery, Brandi; Evrard, Yvonne A.; Doroshow, James H.; Welm, Alana L.; Welm, Bryan E.; Lewis, Michael T.; Fang, Bingliang; Roth, Jack A.; Meric-Bernstam, Funda; Herlyn, Meenhard; Davies, Michael A.; Ding, Li; Li, Shunqiang; Govindan, Ramaswamy; Isella, Claudio; Moscow, Jeffrey A.; Trusolino, Livio; Byrne, Annette T.; Jonkers, Jos; Bult, Carol J.; Medico, Enzo; Chuang, Jeffrey H.; Giordano, Silvia; Corso, Simona;
Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer
2021-01-01 Lafferty, Adam; O'Farrell, Alice C; Migliardi, Giorgia; Khemka, Niraj; Lindner, Andreas U; Sassi, Francesco; Zanella, Eugenia R; Salvucci, Manuela; Vanderheyden, Evy; Modave, Elodie; Boeckx, Bram; Halang, Luise; Betge, Johannes; Ebert, Matthias P A; Dicker, Patrick; Argilés, Guillem; Tabernero, Josep; Dienstmann, Rodrigo; Medico, Enzo; Lambrechts, Diether; Bertotti, Andrea; Isella, Claudio; Trusolino, Livio; Prehn, Jochen H M; Byrne, Annette T
The rna-binding protein esrp1 modulates the expression of rac1b in colorectal cancer cells
2021-01-01 Manco M.; Ala U.; Cantarella D.; Tolosano E.; Medico E.; Altruda F.; Fagoonee S.
Synthetic lethality screening highlights colorectal cancer vulnerability to concomitant blockade of nedd8 and egfr pathways
2021-01-01 Invrea F.; Punzi S.; Petti C.; Minelli R.; Peoples M.D.; Bristow C.A.; Vurchio V.; Corrado A.; Bragoni A.; Marchio' C.; Bertotti A.; Trusolino L.; Bardelli A.; Isella C.; Carugo A.; Draetta G.F.; Medico E.
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype
2020-01-01 Lupo, Barbara; Sassi, Francesco; Pinnelli, Marika; Galimi, Francesco; Zanella, Eugenia R.; Vurchio, Valentina; Migliardi, Giorgia; Gagliardi, Paolo Armando; Puliafito, Alberto; Manganaro, Daria; Luraghi, Paolo; Kragh, Michael; Pedersen, Mikkel W.; Horak, Ivan D.; Boccaccio, Carla; Medico, Enzo; Primo, Luca; Nichol, Daniel; Spiteri, Inmaculada; Heide, Timon; Vatsiou, Alexandra; Graham, Trevor A.; Élez, Elena; Argiles, Guillem; Nuciforo, Paolo; Sottoriva, Andrea; Dienstmann, Rodrigo; Pasini, Diego; Grassi, Elena; Isella, Claudio; Bertotti, Andrea; Trusolino, Livio
Machine learning for RNA sequencing-based intrinsic subtyping of breast cancer
2020-01-01 Cascianelli S.; Molineris I.; Isella C.; Masseroli M.; Medico E.
Improved Outcome Prediction for Appendiceal Pseudomyxoma Peritonei by Integration of Cancer Cell and Stromal Transcriptional Profiles
2020-01-01 Isella, Claudio; Vaira, Marco; Robella, Manuela; Bellomo, Sara Erika; Picco, Gabriele; Borsano, Alice; Mignone, Andrea; Petti, Consalvo; Porporato, Roberta; Ulla, Alexandra Ambra; Pisacane, Alberto; Sapino, Anna; Simone, Michele De; Medico, Enzo
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Comprehensive genomic profiling on metastatic Melanoma: results from a network screening from 7 Italian Cancer Centres | 2024 | Pallocca, Matteo; Molineris, Ivan; Berrino, Enrico; Marcozzi, Benedetta; Betti, Martina; Levati, Lauretta; D'Atri, Stefania; Menin, Chiara; Madonna, Gabriele; Ghiorzo, Paola; Bulgarelli, Jenny; Ferraresi, Virgina; Venesio, Tiziana; Rodolfo, Monica; Rivoltini, Licia; Lanfrancone, Luisa; Ascierto, Paolo Antonio; Mazzarella, Luca; Pelicci, Pier Giuseppe; De Maria, Ruggero; Ciliberto, Gennaro; Medico, Enzo; Russo, Giandomenico | |
| Preclinical efficacy of a HER2 synNotch/CEA-CAR combinatorial immunotherapy against colorectal cancer with HER2 amplification | 2024 | Cortese, Marco; Torchiaro, Erica; D'Andrea, Alice; Petti, Consalvo; Invrea, Federica; Franco, Letizia; Donini, Chiara; Leuci, Valeria; Leto, Simonetta Maria; Vurchio, Valentina; Cottino, Francesca; Isella, Claudio; Arena, Sabrina; Vigna, Elisa; Bertotti, Andrea; Trusolino, Livio; Sangiolo, Dario; Medico, Enzo | |
| Abstract 3998: Preclinical efficacy of a synthetic Notch-based combinatorial immunotherapy against colorectal cancer with HER2 amplification | 2024 | Cortese, Marco; Torchiaro, Erica; D'Andrea, Alice; Petti, Consalvo; Invrea, Federica; Franco, Letizia; Donini, Chiara; Leuci, Valeria; Leto, Simonetta M.; Vurchio, Valentina; Cottino, Francesca; Isella, Claudio; Arena, Sabrina; Vigna, Elisa; Bertotti, Andrea; Trusolino, Livio; Sangiolo, Dario; Medico, Enzo | |
| Multi-label transcriptional classification of colorectal cancer reflects tumor cell population heterogeneity | 2023 | Cascianelli, Silvia; Barbera, Chiara; Ulla, Alexandra Ambra; Grassi, Elena; Lupo, Barbara; Pasini, Diego; Bertotti, Andrea; Trusolino, Livio; Medico, Enzo; Isella, Claudio; Masseroli, Marco | |
| Dual VEGFA/BRAF targeting boosts PD-1 blockade in melanoma through GM-CSF-mediated infiltration of M1 macrophages | 2023 | Comunanza, Valentina; Gigliotti, Chiara; Lamba, Simona; Doronzo, Gabriella; Vallariello, Edoardo; Martin, Valentina; Isella, Claudio; Medico, Enzo; Bardelli, Alberto; Sangiolo, Dario; Di Nicolantonio, Federica; Bussolino, Federico | |
| Case report: Preclinical efficacy of NEDD8 and proteasome inhibitors in patient-derived models of signet ring high-grade mucinous colorectal cancer from a Lynch syndrome patient | 2023 | Torchiaro, Erica; Petti, Consalvo; Arena, Sabrina; Sassi, Francesco; Migliardi, Giorgia; Mellano, Alfredo; Porporato, Roberta; Basiricò, Marco; Gammaitoni, Loretta; Berrino, Enrico; Montone, Monica; Corti, Giorgio; Crisafulli, Giovanni; Marchio', Caterina; Bardelli, Alberto; Medico, Enzo | |
| 213 Design, characterization and preclinical validation of a combinatorial CAR-based immunotherapy against colorectal cancer with HER2 amplification | 2022 | Cortese, Marco; Torchiaro, Erica; Leto, Simonetta; Petti, Consalvo; D'Andrea, Alice; Degree, Master; Invrea, Federica; Arena, Sabrina; Medico, Enzo | |
| The EurOPDX Data Portal: an open platform for patient-derived cancer xenograft data sharing and visualization | 2022 | Dudová, Zdenka; Conte, Nathalie; Mason, Jeremy; Stuchlík, Dalibor; Peša, Radim; Halmagyi, Csaba; Perova, Zinaida; Mosaku, Abayomi; Thorne, Ross; Follette, Alex; Pivarč, Ľuboslav; Šašinka, Radim; Usman, Muhammad; Neuhauser, Steven; Begley, Dale A; Krupke, Debra M; Frassà, Massimiliano; Fiori, Alessandro; Corsi, Riccardo; Vezzadini, Luca; Isella, Claudio; Bertotti, Andrea; Bult, Carol; Parkinson, Helen; Medico, Enzo; Meehan, Terrence; Křenek, Aleš | |
| The neuronal protein Neuroligin 1 promotes colorectal cancer progression by modulating the APC/β-catenin pathway | 2022 | Pergolizzi M, Bizzozero L, Maione F, Maldi E, Isella C, Macagno M, Mariella E, Bardelli A, Medico E, Marchio Caterina, Serini G, Di Nicolantonio F, Bussolino F, Arese M | |
| Mek inhibition in a newborn with raf1-associated noonan syndrome ameliorates hypertrophic cardiomyopathy but is insufficient to revert pulmonary vascular disease | 2022 | Mussa A.; Carli D.; Giorgio E.; Villar A.M.; Cardaropoli S.; Carbonara C.; Campagnoli M.F.; Galletto P.; Palumbo M.; Olivieri S.; Isella C.; Andelfinger G.; Tartaglia M.; Botta G.; Brusco A.; Medico E.; Ferrero G.B. | |
| Successful treatment with MEK-inhibitor in a patient with NRAS-related cutaneous skeletal hypophosphatemia syndrome | 2022 | Carli, Diana; Cardaropoli, Simona; Tessaris, Daniele; Coppo, Paola; La Selva, Roberta; Cesario, Claudia; Lepri, Francesca Romana; Pullano, Verdiana; Palumbo, Martina; Ramenghi, Ugo; Brusco, Alfredo; Medico, Enzo; De Sanctis, Luisa; Ferrero, Giovanni Battista; Mussa, Alessandro | |
| A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine | 2022 | Sebastian, Carlos; Ferrer, Christina; Serra, Maria; Choi, Jee-Eun; Ducano, Nadia; Mira, Alessia; Shah, Manasvi S; Stopka, Sylwia A; Perciaccante, Andrew J; Isella, Claudio; Moya-Rull, Daniel; Vara-Messler, Marianela; Giordano, Silvia; Maldi, Elena; Desai, Niyati; Capen, Diane E; Medico, Enzo; Cetinbas, Murat; Sadreyev, Ruslan I; Brown, Dennis; Rivera, Miguel N; Sapino, Anna; Breault, David T; Agar, Nathalie Y R; Mostoslavsky, Raul | |
| The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation | 2021 | Fiorito V.; Allocco A.L.; Petrillo S.; Gazzano E.; Torretta S.; Marchi S.; Destefanis F.; Pacelli C.; Audrito V.; Provero P.; Medico E.; Chiabrando D.; Porporato P.E.; Cancelliere C.; Bardelli A.; Trusolino L.; Capitanio N.; Deaglio S.; Altruda F.; Pinton P.; Cardaci S.; Riganti C.; Tolosano E. | |
| Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts | 2021 | Woo, Xing Yi; Giordano, Jessica; Srivastava, Anuj; Zhao, Zi-Ming; Lloyd, Michael W.; de Bruijn, Roebi; Suh, Yun-Suhk; Patidar, Rajesh; Chen, Li; Scherer, Sandra; Bailey, Matthew H.; Yang, Chieh-Hsiang; Cortes-Sanchez, Emilio; Xi, Yuanxin; Wang, Jing; Wickramasinghe, Jayamanna; Kossenkov, Andrew V.; Rebecca, Vito W.; Sun, Hua; Mashl, R. Jay; Davies, Sherri R.; Jeon, Ryan; Frech, Christian; Randjelovic, Jelena; Rosains, Jacqueline; Galimi, Francesco; Bertotti, Andrea; Lafferty, Adam; O’Farrell, Alice C.; Modave, Elodie; Lambrechts, Diether; ter Brugge, Petra; Serra, Violeta; Marangoni, Elisabetta; El Botty, Rania; Kim, Hyunsoo; Kim, Jong-Il; Yang, Han-Kwang; Lee, Charles; Dean, Dennis A.; Davis-Dusenbery, Brandi; Evrard, Yvonne A.; Doroshow, James H.; Welm, Alana L.; Welm, Bryan E.; Lewis, Michael T.; Fang, Bingliang; Roth, Jack A.; Meric-Bernstam, Funda; Herlyn, Meenhard; Davies, Michael A.; Ding, Li; Li, Shunqiang; Govindan, Ramaswamy; Isella, Claudio; Moscow, Jeffrey A.; Trusolino, Livio; Byrne, Annette T.; Jonkers, Jos; Bult, Carol J.; Medico, Enzo; Chuang, Jeffrey H.; Giordano, Silvia; Corso, Simona; | |
| Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer | 2021 | Lafferty, Adam; O'Farrell, Alice C; Migliardi, Giorgia; Khemka, Niraj; Lindner, Andreas U; Sassi, Francesco; Zanella, Eugenia R; Salvucci, Manuela; Vanderheyden, Evy; Modave, Elodie; Boeckx, Bram; Halang, Luise; Betge, Johannes; Ebert, Matthias P A; Dicker, Patrick; Argilés, Guillem; Tabernero, Josep; Dienstmann, Rodrigo; Medico, Enzo; Lambrechts, Diether; Bertotti, Andrea; Isella, Claudio; Trusolino, Livio; Prehn, Jochen H M; Byrne, Annette T | |
| The rna-binding protein esrp1 modulates the expression of rac1b in colorectal cancer cells | 2021 | Manco M.; Ala U.; Cantarella D.; Tolosano E.; Medico E.; Altruda F.; Fagoonee S. | |
| Synthetic lethality screening highlights colorectal cancer vulnerability to concomitant blockade of nedd8 and egfr pathways | 2021 | Invrea F.; Punzi S.; Petti C.; Minelli R.; Peoples M.D.; Bristow C.A.; Vurchio V.; Corrado A.; Bragoni A.; Marchio' C.; Bertotti A.; Trusolino L.; Bardelli A.; Isella C.; Carugo A.; Draetta G.F.; Medico E. | |
| Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype | 2020 | Lupo, Barbara; Sassi, Francesco; Pinnelli, Marika; Galimi, Francesco; Zanella, Eugenia R.; Vurchio, Valentina; Migliardi, Giorgia; Gagliardi, Paolo Armando; Puliafito, Alberto; Manganaro, Daria; Luraghi, Paolo; Kragh, Michael; Pedersen, Mikkel W.; Horak, Ivan D.; Boccaccio, Carla; Medico, Enzo; Primo, Luca; Nichol, Daniel; Spiteri, Inmaculada; Heide, Timon; Vatsiou, Alexandra; Graham, Trevor A.; Élez, Elena; Argiles, Guillem; Nuciforo, Paolo; Sottoriva, Andrea; Dienstmann, Rodrigo; Pasini, Diego; Grassi, Elena; Isella, Claudio; Bertotti, Andrea; Trusolino, Livio | |
| Machine learning for RNA sequencing-based intrinsic subtyping of breast cancer | 2020 | Cascianelli S.; Molineris I.; Isella C.; Masseroli M.; Medico E. | |
| Improved Outcome Prediction for Appendiceal Pseudomyxoma Peritonei by Integration of Cancer Cell and Stromal Transcriptional Profiles | 2020 | Isella, Claudio; Vaira, Marco; Robella, Manuela; Bellomo, Sara Erika; Picco, Gabriele; Borsano, Alice; Mignone, Andrea; Petti, Consalvo; Porporato, Roberta; Ulla, Alexandra Ambra; Pisacane, Alberto; Sapino, Anna; Simone, Michele De; Medico, Enzo |
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