Sfoglia per Autore
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer
2024-01-01 Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; McCooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D.
Repurposed AT9283 triggers anti-tumoral effects by targeting MKK3 oncogenic functions in Colorectal Cancer
2024-01-01 Piastra, Valentina; Ganci, Federica; Sacconi, Andrea; Pranteda, Angelina; Allegretti, Matteo; Bernardini, Roberta; Serra, Martina; Lupo, Barbara; Dell'Aquila, Emanuela; Ferretti, Gianluigi; Pescarmona, Edoardo; Bartolazzi, Armando; Blandino, Giovanni; Trusolino, Livio; Bossi, Gianluca
Preclinical efficacy of a HER2 synNotch/CEA-CAR combinatorial immunotherapy against colorectal cancer with HER2 amplification
2024-01-01 Cortese, Marco; Torchiaro, Erica; D'Andrea, Alice; Petti, Consalvo; Invrea, Federica; Franco, Letizia; Donini, Chiara; Leuci, Valeria; Leto, Simonetta Maria; Vurchio, Valentina; Cottino, Francesca; Isella, Claudio; Arena, Sabrina; Vigna, Elisa; Bertotti, Andrea; Trusolino, Livio; Sangiolo, Dario; Medico, Enzo
Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells
2024-01-01 Sogari, Alberto; Rovera, Emanuele; Grasso, Gaia; Mariella, Elisa; Reilly, Nicole Megan; Lamba, Simona; Mauri, Gianluca; Durinikova, Erika; Vitiello, Pietro Paolo; Lorenzato, Annalisa; Avolio, Marco; Piumatti, Eleonora; Bonoldi, Emanuela; Aquilano, Maria Costanza; Arena, Sabrina; Sartore-Bianchi, Andrea; Siena, Salvatore; Trusolino, Livio; Donalisio, Manuela; Russo, Mariangela; Di Nicolantonio, Federica; Lembo, David; Bardelli, Alberto
Abstract 3998: Preclinical efficacy of a synthetic Notch-based combinatorial immunotherapy against colorectal cancer with HER2 amplification
2024-01-01 Cortese, Marco; Torchiaro, Erica; D'Andrea, Alice; Petti, Consalvo; Invrea, Federica; Franco, Letizia; Donini, Chiara; Leuci, Valeria; Leto, Simonetta M.; Vurchio, Valentina; Cottino, Francesca; Isella, Claudio; Arena, Sabrina; Vigna, Elisa; Bertotti, Andrea; Trusolino, Livio; Sangiolo, Dario; Medico, Enzo
XENTURION is a population-level multidimensional resource of xenografts and tumoroids from metastatic colorectal cancer patients
2024-01-01 Leto, Simonetta M.; Grassi, Elena; Avolio, Marco; Vurchio, Valentina; Cottino, Francesca; Ferri, Martina; Zanella, Eugenia R.; Borgato, Sofia; Corti, Giorgio; di Blasio, Laura; Somale, Desiana; Vara-Messler, Marianela; Galimi, Francesco; Sassi, Francesco; Lupo, Barbara; Catalano, Irene; Pinnelli, Marika; Viviani, Marco; Sperti, Luca; Mellano, Alfredo; Ferrero, Alessandro; Zingaretti, Caterina C.; Puliafito, Alberto; Primo, Luca; Bertotti, Andrea; Trusolino, Livio
An mTOR feedback loop mediates the 'flare' ('rebound') response to MET tyrosine kinase inhibition
2023-01-01 Altintas, D M; Cerqua, M; De Laurentiis, A; Trusolino, L; Boccaccio, C; Comoglio, P M
Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT)
2023-01-01 Marta Falcinelli , Giulia Dell’Omo, Elena Grassi , Elisa Mariella, Simonetta Maria Leto, Sharon Scardellato, Annalisa Lorenzato, Sabrina Arena , Andrea Bertotti, Livio Trusolino , Alberto Bardelli, Fabrizio d’Adda di Fagagna
Abstract 5900: Tolerance to colibactin correlates with response to chemotherapeutic agents in colorectal cancer
2023-01-01 Sogari, Alberto; Rovera, Emanuele; Reilly, Nicole Megan; Lamba, Simona; Russo, Mariangela; Lorenzato, Annalisa; Durinikova, Erika; Trusolino, Livio; Arena, Sabrina; Donalisio, Manuela; Nicolantonio, Federica Di; Lembo, David; Bardelli, Alberto
MicroRNA 483-3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT axis
2023-01-01 Candiello, Ermes; Reato, Gigliola; Verginelli, Federica; Gambardella, Gennaro; D Ambrosio, Antonio; Calandra, Noemi; Orzan, Francesca; Iuliano, Antonella; Albano, Raffaella; Sassi, Francesco; Luraghi, Paolo; Comoglio, Paolo M; Bertotti, Andrea; Trusolino, Livio; Boccaccio, Carla
Synthetic Lethal Interaction with BCL-XL Blockade Deepens Response to Cetuximab in Patient-Derived Models of Metastatic Colorectal Cancer
2023-01-01 Leto, Simonetta M; Ferri, Martina; Sassi, Francesco; Zanella, Eugenia R; Cottino, Francesca; Vurchio, Valentina; Catalano, Irene; Ferrero, Alessandro; Zingaretti, Caterina C; Marchio', Caterina; Grassi, Elena; Trusolino, Livio; Bertotti, Andrea
CONNECTOR, fitting and clustering of longitudinal data to reveal a new risk stratification system
2023-01-01 Pernice, Simone; Sirovich, Roberta; Grassi, Elena; Viviani, Marco; Ferri, Martina; Sassi, Francesco; Alessandrì, Luca; Tortarolo, Dora; Calogero, Raffaele A; Trusolino, Livio; Bertotti, Andrea; Beccuti, Marco; Olivero, Martina; Cordero, Francesca
Multi-label transcriptional classification of colorectal cancer reflects tumor cell population heterogeneity
2023-01-01 Cascianelli, Silvia; Barbera, Chiara; Ulla, Alexandra Ambra; Grassi, Elena; Lupo, Barbara; Pasini, Diego; Bertotti, Andrea; Trusolino, Livio; Medico, Enzo; Isella, Claudio; Masseroli, Marco
EGAsubmitter: A software to automate submission of nucleic acid sequencing data to the European Genome-phenome Archive
2023-01-01 Viviani, Marco; Montemurro, Marilisa; Trusolino, Livio; Bertotti, Andrea; Urgese, Gianvito; Grassi, Elena
Phosphoproteomics of patient-derived xenographs identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer
2023-01-01 Beekhof, Robin; Bertotti, Andrea; Böttger, Franziska; Vurchio, Valentina; Cottino, Francesca; Zanella, Eugenia R; Migliardi, Giorgia; Viviani, Marco; Grassi, Elena; Lupo, Barbara; Henneman, Alex A; Knol, Jaco C; Pham, Thang V; de Goeij-de Haas, Richard; Piersma, Sander R; Labots, Mariette; Verheul, Henk M W; Trusolino, Livio; Jimenez, Connie R
Towards precision oncology with patient-derived xenografts
2022-01-01 Zanella, Eugenia R; Grassi, Elena; Trusolino, Livio
TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p in colorectal cancer
2022-01-01 Dinami, Roberto; Petti, Eleonora; Porru, Manuela; Rizzo, Angela; Ganci, Federica; Sacconi, Andrea; Ostano, Paola; Chiorino, Giovanna; Trusolino, Livio; Blandino, Giovanni; Ciliberto, Gennaro; Zizza, Pasquale; Biroccio, Annamaria
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia
2022-01-01 Vasquez, Ester Gil; Nasreddin, Nadia; Valbuena, Gabriel N; Mulholland, Eoghan J; Belnoue-Davis, Hayley L; Eggington, Holly R; Schenck, Ryan O; Wouters, Valérie M; Wirapati, Pratyaksha; Gilroy, Kathryn; Lannagan, Tamsin R M; Flanagan, Dustin J; Najumudeen, Arafath K; Omwenga, Sulochana; McCorry, Amy M B; Easton, Alistair; Koelzer, Viktor H; East, James E; Morton, Dion; Trusolino, Livio; Maughan, Timothy; Campbell, Andrew D; Loughrey, Maurice B; Dunne, Philip D; Tsantoulis, Petros; Huels, David J; Tejpar, Sabine; Sansom, Owen J; Leedham, Simon J
Chromatin Velocity reveals epigenetic dynamics by single-cell profiling of heterochromatin and euchromatin
2022-01-01 Tedesco, Martina; Giannese, Francesca; Lazarević, Dejan; Giansanti, Valentina; Rosano, Dalia; Monzani, Silvia; Catalano, Irene; Grassi, Elena; Zanella, Eugenia R; Botrugno, Oronza A; Morelli, Leonardo; Panina Bordignon, Paola; Caravagna, Giulio; Bertotti, Andrea; Martino, Gianvito; Aldrighetti, Luca; Pasqualato, Sebastiano; Trusolino, Livio; Cittaro, Davide; Tonon, Giovanni
Effective drug combinations in breast, colon and pancreatic cancer cells
2022-01-01 Jaaks P.; Coker E.A.; Vis D.J.; Edwards O.; Carpenter E.F.; Leto S.M.; Dwane L.; Sassi F.; Lightfoot H.; Barthorpe S.; van der Meer D.; Yang W.; Beck A.; Mironenko T.; Hall C.; Hall J.; Mali I.; Richardson L.; Tolley C.; Morris J.; Thomas F.; Lleshi E.; Aben N.; Benes C.H.; Bertotti A.; Trusolino L.; Wessels L.; Garnett M.J.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer | 2024 | Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; McCooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D. | |
| Repurposed AT9283 triggers anti-tumoral effects by targeting MKK3 oncogenic functions in Colorectal Cancer | 2024 | Piastra, Valentina; Ganci, Federica; Sacconi, Andrea; Pranteda, Angelina; Allegretti, Matteo; Bernardini, Roberta; Serra, Martina; Lupo, Barbara; Dell'Aquila, Emanuela; Ferretti, Gianluigi; Pescarmona, Edoardo; Bartolazzi, Armando; Blandino, Giovanni; Trusolino, Livio; Bossi, Gianluca | |
| Preclinical efficacy of a HER2 synNotch/CEA-CAR combinatorial immunotherapy against colorectal cancer with HER2 amplification | 2024 | Cortese, Marco; Torchiaro, Erica; D'Andrea, Alice; Petti, Consalvo; Invrea, Federica; Franco, Letizia; Donini, Chiara; Leuci, Valeria; Leto, Simonetta Maria; Vurchio, Valentina; Cottino, Francesca; Isella, Claudio; Arena, Sabrina; Vigna, Elisa; Bertotti, Andrea; Trusolino, Livio; Sangiolo, Dario; Medico, Enzo | |
| Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells | 2024 | Sogari, Alberto; Rovera, Emanuele; Grasso, Gaia; Mariella, Elisa; Reilly, Nicole Megan; Lamba, Simona; Mauri, Gianluca; Durinikova, Erika; Vitiello, Pietro Paolo; Lorenzato, Annalisa; Avolio, Marco; Piumatti, Eleonora; Bonoldi, Emanuela; Aquilano, Maria Costanza; Arena, Sabrina; Sartore-Bianchi, Andrea; Siena, Salvatore; Trusolino, Livio; Donalisio, Manuela; Russo, Mariangela; Di Nicolantonio, Federica; Lembo, David; Bardelli, Alberto | |
| Abstract 3998: Preclinical efficacy of a synthetic Notch-based combinatorial immunotherapy against colorectal cancer with HER2 amplification | 2024 | Cortese, Marco; Torchiaro, Erica; D'Andrea, Alice; Petti, Consalvo; Invrea, Federica; Franco, Letizia; Donini, Chiara; Leuci, Valeria; Leto, Simonetta M.; Vurchio, Valentina; Cottino, Francesca; Isella, Claudio; Arena, Sabrina; Vigna, Elisa; Bertotti, Andrea; Trusolino, Livio; Sangiolo, Dario; Medico, Enzo | |
| XENTURION is a population-level multidimensional resource of xenografts and tumoroids from metastatic colorectal cancer patients | 2024 | Leto, Simonetta M.; Grassi, Elena; Avolio, Marco; Vurchio, Valentina; Cottino, Francesca; Ferri, Martina; Zanella, Eugenia R.; Borgato, Sofia; Corti, Giorgio; di Blasio, Laura; Somale, Desiana; Vara-Messler, Marianela; Galimi, Francesco; Sassi, Francesco; Lupo, Barbara; Catalano, Irene; Pinnelli, Marika; Viviani, Marco; Sperti, Luca; Mellano, Alfredo; Ferrero, Alessandro; Zingaretti, Caterina C.; Puliafito, Alberto; Primo, Luca; Bertotti, Andrea; Trusolino, Livio | |
| An mTOR feedback loop mediates the 'flare' ('rebound') response to MET tyrosine kinase inhibition | 2023 | Altintas, D M; Cerqua, M; De Laurentiis, A; Trusolino, L; Boccaccio, C; Comoglio, P M | |
| Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT) | 2023 | Marta Falcinelli , Giulia Dell’Omo, Elena Grassi , Elisa Mariella, Simonetta Maria Leto, Sharon Scardellato, Annalisa Lorenzato, Sabrina Arena , Andrea Bertotti, Livio Trusolino , Alberto Bardelli, Fabrizio d’Adda di Fagagna | |
| Abstract 5900: Tolerance to colibactin correlates with response to chemotherapeutic agents in colorectal cancer | 2023 | Sogari, Alberto; Rovera, Emanuele; Reilly, Nicole Megan; Lamba, Simona; Russo, Mariangela; Lorenzato, Annalisa; Durinikova, Erika; Trusolino, Livio; Arena, Sabrina; Donalisio, Manuela; Nicolantonio, Federica Di; Lembo, David; Bardelli, Alberto | |
| MicroRNA 483-3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT axis | 2023 | Candiello, Ermes; Reato, Gigliola; Verginelli, Federica; Gambardella, Gennaro; D Ambrosio, Antonio; Calandra, Noemi; Orzan, Francesca; Iuliano, Antonella; Albano, Raffaella; Sassi, Francesco; Luraghi, Paolo; Comoglio, Paolo M; Bertotti, Andrea; Trusolino, Livio; Boccaccio, Carla | |
| Synthetic Lethal Interaction with BCL-XL Blockade Deepens Response to Cetuximab in Patient-Derived Models of Metastatic Colorectal Cancer | 2023 | Leto, Simonetta M; Ferri, Martina; Sassi, Francesco; Zanella, Eugenia R; Cottino, Francesca; Vurchio, Valentina; Catalano, Irene; Ferrero, Alessandro; Zingaretti, Caterina C; Marchio', Caterina; Grassi, Elena; Trusolino, Livio; Bertotti, Andrea | |
| CONNECTOR, fitting and clustering of longitudinal data to reveal a new risk stratification system | 2023 | Pernice, Simone; Sirovich, Roberta; Grassi, Elena; Viviani, Marco; Ferri, Martina; Sassi, Francesco; Alessandrì, Luca; Tortarolo, Dora; Calogero, Raffaele A; Trusolino, Livio; Bertotti, Andrea; Beccuti, Marco; Olivero, Martina; Cordero, Francesca | |
| Multi-label transcriptional classification of colorectal cancer reflects tumor cell population heterogeneity | 2023 | Cascianelli, Silvia; Barbera, Chiara; Ulla, Alexandra Ambra; Grassi, Elena; Lupo, Barbara; Pasini, Diego; Bertotti, Andrea; Trusolino, Livio; Medico, Enzo; Isella, Claudio; Masseroli, Marco | |
| EGAsubmitter: A software to automate submission of nucleic acid sequencing data to the European Genome-phenome Archive | 2023 | Viviani, Marco; Montemurro, Marilisa; Trusolino, Livio; Bertotti, Andrea; Urgese, Gianvito; Grassi, Elena | |
| Phosphoproteomics of patient-derived xenographs identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer | 2023 | Beekhof, Robin; Bertotti, Andrea; Böttger, Franziska; Vurchio, Valentina; Cottino, Francesca; Zanella, Eugenia R; Migliardi, Giorgia; Viviani, Marco; Grassi, Elena; Lupo, Barbara; Henneman, Alex A; Knol, Jaco C; Pham, Thang V; de Goeij-de Haas, Richard; Piersma, Sander R; Labots, Mariette; Verheul, Henk M W; Trusolino, Livio; Jimenez, Connie R | |
| Towards precision oncology with patient-derived xenografts | 2022 | Zanella, Eugenia R; Grassi, Elena; Trusolino, Livio | |
| TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p in colorectal cancer | 2022 | Dinami, Roberto; Petti, Eleonora; Porru, Manuela; Rizzo, Angela; Ganci, Federica; Sacconi, Andrea; Ostano, Paola; Chiorino, Giovanna; Trusolino, Livio; Blandino, Giovanni; Ciliberto, Gennaro; Zizza, Pasquale; Biroccio, Annamaria | |
| Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia | 2022 | Vasquez, Ester Gil; Nasreddin, Nadia; Valbuena, Gabriel N; Mulholland, Eoghan J; Belnoue-Davis, Hayley L; Eggington, Holly R; Schenck, Ryan O; Wouters, Valérie M; Wirapati, Pratyaksha; Gilroy, Kathryn; Lannagan, Tamsin R M; Flanagan, Dustin J; Najumudeen, Arafath K; Omwenga, Sulochana; McCorry, Amy M B; Easton, Alistair; Koelzer, Viktor H; East, James E; Morton, Dion; Trusolino, Livio; Maughan, Timothy; Campbell, Andrew D; Loughrey, Maurice B; Dunne, Philip D; Tsantoulis, Petros; Huels, David J; Tejpar, Sabine; Sansom, Owen J; Leedham, Simon J | |
| Chromatin Velocity reveals epigenetic dynamics by single-cell profiling of heterochromatin and euchromatin | 2022 | Tedesco, Martina; Giannese, Francesca; Lazarević, Dejan; Giansanti, Valentina; Rosano, Dalia; Monzani, Silvia; Catalano, Irene; Grassi, Elena; Zanella, Eugenia R; Botrugno, Oronza A; Morelli, Leonardo; Panina Bordignon, Paola; Caravagna, Giulio; Bertotti, Andrea; Martino, Gianvito; Aldrighetti, Luca; Pasqualato, Sebastiano; Trusolino, Livio; Cittaro, Davide; Tonon, Giovanni | |
| Effective drug combinations in breast, colon and pancreatic cancer cells | 2022 | Jaaks P.; Coker E.A.; Vis D.J.; Edwards O.; Carpenter E.F.; Leto S.M.; Dwane L.; Sassi F.; Lightfoot H.; Barthorpe S.; van der Meer D.; Yang W.; Beck A.; Mironenko T.; Hall C.; Hall J.; Mali I.; Richardson L.; Tolley C.; Morris J.; Thomas F.; Lleshi E.; Aben N.; Benes C.H.; Bertotti A.; Trusolino L.; Wessels L.; Garnett M.J. |
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