Sfoglia per Autore
Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor.
1991-01-01 Naldini L; Weidner KM; Vigna E; Gaudino G; Bardelli A; Ponzetto C; Narsimhan RP; Hartmann G; Zarnegar R; Michalopoulos GK; Birchmeier W; Comoglio PM
Autophosphorylation promotes complex formation of recombinant hepatocyte growth factor receptor with cytoplasmic effectors containing SH2 domains.
1992-01-01 BARDELLI A ;MAINA F ;GOUT I ;FRY MJ ;WATERFIELD MD ;COMOGLIO PM ;PONZETTO C
A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor
1993-01-01 Ponzetto C; Bardelli A; Maina F; Longati P; Panayotou G; Dhand R; Waterfield MD; Comoglio PM
A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family.
1994-01-01 PONZETTO C; BARDELLI A; ZHEN Z; MAINA F; DALLA ZONCA P; GIORDANO S; GRAZIANI A; PANAYOTOU G; P. COMOGLIO
Identification of functional domains in the hepatocyte growth factor and its receptor by molecular engineering.
1994-01-01 BARDELLI A ;PONZETTO C ;COMOGLIO PM
Tyrosines1234-1235 are critical for activation of the tyrosine kinase encoded by the MET proto-oncogene (HGF receptor).
1994-01-01 LONGATI P; BARDELLI A; PONZETTO C; NALDINI L; COMOGLIO PM
Hepatocyte growth factor and its receptor, the tyrosine kinase encoded by the c-MET proto-oncogene.
1994-01-01 VIGNA E ;NALDINI L ;TAMAGNONE L ;LONGATI P ;BARDELLI A ;MAINA F ;PONZETTO C ;COMOGLIO PM
The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein.
1995-01-01 PELICCI G; GIORDANO S; ZHEN Z; SALCINI AE; LANFRANCONE L; BARDELLI A; PANAYOTOU G; WATERFIELD MD; PONZETTO C; PELICCI PG
Biological activation of pro-HGF (hepatocyte growth factor) by urokinase is controlled by a stoichiometric reaction.
1995-01-01 NALDINI L ;VIGNA E ;BARDELLI A ;FOLLENZI A ;GALIMI F ;COMOGLIO PM
HGF receptor associates with the anti-apoptotic protein BAG-1 and prevents cell death
1996-01-01 BARDELLI A;LONGATI P;ALBERO D;GORUPPI S;SCHNEIDER C;PONZETTO C;COMOGLIO PM
The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma
1996-01-01 BORRELLO M.G.; ALBERTI L.; ARIGHI E.; BONGARZONE I.; BATTISTINI C.; BARDELLI A.; PASINI B.; PIUTTI C.; RIZZETTI M.G.; MONDELLINI P.; RADICE M.T.; PIEROTTI M.A.
Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility
1996-01-01 C. PONZETTO; Z. ZHEN; E. AUDERO; F. MAINA; A. BARDELLI; M.L. BASILE; S. GIORDANO; R. NARSIMHAN; P. COMOGLIO
A point mutation in the MET oncogene abrogates metastasis without affecting transformation.
1997-01-01 GIORDANO S; BARDELLI A; ZHEN Z; MENARD S; PONZETTO C; COMOGLIO PM
Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.
1997-01-01 BARDELLI A ;LONGATI P ;GRAMAGLIA D ;STELLA MC ;COMOGLIO PM
Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2.
1997-01-01 BESSER D; BARDELLI A; DIDICHENKO S; THELEN M; COMOGLIO P ; PONZETTO C; NAGAMINE Y
Scatter factor receptors are key players in a unique multistep program leading to invasive growth.
1997-01-01 BARDELLI A ;COMOGLIO PM
"Invasive-growth" signaling by the Met/HGF receptor: the hereditary renal carcinoma connection
1997-01-01 BARDELLI A ;PUGLIESE L ;COMOGLIO PM
Peptide Antagonists of Cellular Mitogenesis and Motogenesis and Their Therapeutic Use
1997-01-01 BATTISTINI C; GIORDANO P; DE ROSA S; CORRADI F; COMOGLIO P; BARDELLI A
Induction of epithelial tubules by growth factor HGF depends on the STAT pathway.
1998-01-01 BOCCACCIO C ;ANDÒ M ;TAMAGNONE L ;BARDELLI A ;MICHIELI P ;BATTISTINI C ;COMOGLIO PM
Protein tyrosine phosphatase PTP-S binds to the juxtamembrane region of the hepatocyte growth factor receptor Met.
1998-01-01 VILLA-MORUZZI E ;PUNTONI F ;BARDELLI A ;VIGNA E ;DE ROSA S ;COMOGLIO PM
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