Sfoglia per Autore
Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer
2019-01-01 Bacci M.; Lorito N.; Ippolito L.; Ramazzotti M.; Luti S.; Romagnoli S.; Parri M.; Bianchini F.; Cappellesso F.; Virga F.; Gao Q.; Simoes B.M.; Marangoni E.; Martin L.-A.; Comito G.; Ferracin M.; Giannoni E.; Mazzone M.; Chiarugi P.; Morandi A.
Tumor-associated macrophages: a short compendium
2019-01-01 Prenen H.; Mazzone M.
The reciprocal function and regulation of tumor vessels and immune cells offers new therapeutic opportunities in cancer
2018-01-01 Missiaen R.; Mazzone M.; Bergers G.
Neutrophils enhance early Trypanosoma brucei infection onset
2018-01-01 Caljon G.; Mabille D.; Stijlemans B.; De Trez C.; Mazzone M.; Tacchini-Cottier F.; Malissen M.; A. Van Ginderachter J.; Magez S.; De Baetselier P.; Van Den Abbeele J.
Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation
2018-01-01 Bruning U.; Morales-Rodriguez F.; Kalucka J.; Goveia J.; Taverna F.; Queiroz K.C.S.; Dubois C.; Cantelmo A.R.; Chen R.; Loroch S.; Timmerman E.; Caixeta V.; Bloch K.; Conradi L.-C.; Treps L.; Staes A.; Gevaert K.; Tee A.; Dewerchin M.; Semenkovich C.F.; Impens F.; Schilling B.; Verdin E.; Swinnen J.V.; Meier J.L.; Kulkarni R.A.; Sickmann A.; Ghesquiere B.; Schoonjans L.; Li X.; Mazzone M.; Carmeliet P.
Metabolism and TAM functions—it takes two to tango
2018-01-01 Mazzone M.; Menga A.; Castegna A.
Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis
2018-01-01 Kalucka J.; Bierhansl L.; Conchinha N.V.; Missiaen R.; Elia I.; Bruning U.; Scheinok S.; Treps L.; Cantelmo A.R.; Dubois C.; de Zeeuw P.; Goveia J.; Zecchin A.; Taverna F.; Morales-Rodriguez F.; Brajic A.; Conradi L.-C.; Schoors S.; Harjes U.; Vriens K.; Pilz G.-A.; Chen R.; Cubbon R.; Thienpont B.; Cruys B.; Wong B.W.; Ghesquiere B.; Dewerchin M.; De Bock K.; Sagaert X.; Jessberger S.; Jones E.A.V.; Gallez B.; Lambrechts D.; Mazzone M.; Eelen G.; Li X.; Fendt S.-M.; Carmeliet P.
Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy
2018-01-01 Smeets D.; Miller I.S.; O'Connor D.P.; Das S.; Moran B.; Boeckx B.; Gaiser T.; Betge J.; Barat A.; Klinger R.; van Grieken N.C.T.; Cremolini C.; Prenen H.; Mazzone M.; Depreeuw J.; Bacon O.; Fender B.; Brady J.; Hennessy B.T.; McNamara D.A.; Kay E.; Verheul H.M.; Maarten N.; Gallagher W.M.; Murphy V.; Prehn J.H.M.; Koopman M.; Punt C.J.A.; Loupakis F.; Ebert M.P.A.; Ylstra B.; Lambrechts D.; Byrne A.T.
Inhibition of prolyl hydroxylase domain proteins selectively enhances venous thrombus neovascularisation
2018-01-01 Grover S.P.; Saha P.; Humphries J.; Lyons O.T.; Patel A.S.; Serneels J.; Modarai B.; Mazzone M.; Smith A.
Loss of Caveolin-1 in Metastasis-Associated Macrophages Drives Lung Metastatic Growth through Increased Angiogenesis
2017-01-01 Celus W.; Di Conza G.; Oliveira A.I.; Ehling M.; Costa B.M.; Wenes M.; Mazzone M.
Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells
2017-01-01 Palmieri E.M.; Menga A.; Lebrun A.; Hooper D.C.; Butterfield D.A.; Mazzone M.; Castegna A.
The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia
2017-01-01 Di Conza G.; Trusso Cafarello S.; Loroch S.; Mennerich D.; Deschoemaeker S.; Di Matteo M.; Ehling M.; Gevaert K.; Prenen H.; Zahedi R.P.; Sickmann A.; Kietzmann T.; Moretti F.; Mazzone M.
Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis
2017-01-01 Martin-Perez R.; Yerbes R.; Mora-Molina R.; Cano-Gonzalez A.; Arribas J.; Mazzone M.; Lopez-Rivas A.; Palacios C.
Retinoid X receptor suppresses a metastasis-promoting transcriptional program in myeloid cells via a ligand-insensitive mechanism
2017-01-01 Kiss M.; Czimmerer Z.; Nagy G.; Bieniasz-Krzywiec P.; Ehling M.; Pap A.; Poliska S.; Boto P.; Tzerpos P.; Horvath A.; Kolostyak Z.; Daniel B.; Szatmari I.; Mazzone M.; Nagy L.
Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses
2017-01-01 Sadiku P.; Willson J.A.; Dickinson R.S.; Murphy F.; Harris A.J.; Lewis A.; Sammut D.; Mirchandani A.S.; Ryan E.; Watts E.R.; Thompson A.A.R.; Marriott H.M.; Dockrell D.H.; Taylor C.T.; Schneider M.; Maxwell P.H.; Chilvers E.R.; Mazzone M.; Moral V.; Pugh C.W.; Ratcliffe P.J.; Schofield C.J.; Ghesquiere B.; Carmeliet P.; Whyte M.K.B.; Walmsley S.R.
Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium
2017-01-01 Reid S.E.; Kay E.J.; Neilson L.J.; Henze A.-T.; Serneels J.; McGhee E.J.; Dhayade S.; Nixon C.; Mackey J.B.G.; Santi A.; Swaminathan K.; Athineos D.; Papalazarou V.; Patella F.; Roman-Fernandez A.; ElMaghloob Y.; Hernandez-Fernaud J.R.; Adams R.H.; Ismail S.; Bryant D.M.; Salmeron-Sanchez M.; Machesky L.M.; Carlin L.M.; Blyth K.; Mazzone M.; Zanivan S.
α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming
2017-01-01 Liu P.-S.; Wang H.; Li X.; Chao T.; Teav T.; Christen S.; DI Conza G.; Cheng W.-C.; Chou C.-H.; Vavakova M.; Muret C.; Debackere K.; Mazzone M.; Huang H.-D.; Fendt S.-M.; Ivanisevic J.; Ho P.-C.
Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis
2017-01-01 Palmieri E.M.; Menga A.; Martin-Perez R.; Quinto A.; Riera-Domingo C.; De Tullio G.; Hooper D.C.; Lamers W.H.; Ghesquiere B.; McVicar D.W.; Guarini A.; Mazzone M.; Castegna A.
Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism
2017-01-01 Thompson A.A.R.; Dickinson R.S.; Murphy F.; Thomson J.P.; Marriott H.M.; Tavares A.; Willson J.; Williams L.; Lewis A.; Mirchandani A.; Coelho P.D.S.; Doherty C.; Ryan E.; Watts E.; Morton N.M.; Forbes S.; Stimson R.H.; Hameed A.G.; Arnold N.; Preston J.A.; Lawrie A.; Finisguerra V.; Mazzone M.; Sadiku P.; Goveia J.; Taverna F.; Carmeliet P.; Foster S.J.; Chilvers E.R.; Cowburn A.S.; Dockrell D.H.; Johnson R.S.; Meehan R.R.; Whyte M.K.B.; Walmsley S.R.
Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth
2017-01-01 Mathivet T.; Bouleti C.; Van Woensel M.; Stanchi F.; Verschuere T.; Phng L.-K.; Dejaegher J.; Balcer M.; Matsumoto K.; Georgieva P.B.; Belmans J.; Sciot R.; Stockmann C.; Mazzone M.; De Vleeschouwer S.; Gerhardt H.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer | 2019 | Bacci M.; Lorito N.; Ippolito L.; Ramazzotti M.; Luti S.; Romagnoli S.; Parri M.; Bianchini F.; Cappellesso F.; Virga F.; Gao Q.; Simoes B.M.; Marangoni E.; Martin L.-A.; Comito G.; Ferracin M.; Giannoni E.; Mazzone M.; Chiarugi P.; Morandi A. | |
| Tumor-associated macrophages: a short compendium | 2019 | Prenen H.; Mazzone M. | |
| The reciprocal function and regulation of tumor vessels and immune cells offers new therapeutic opportunities in cancer | 2018 | Missiaen R.; Mazzone M.; Bergers G. | |
| Neutrophils enhance early Trypanosoma brucei infection onset | 2018 | Caljon G.; Mabille D.; Stijlemans B.; De Trez C.; Mazzone M.; Tacchini-Cottier F.; Malissen M.; A. Van Ginderachter J.; Magez S.; De Baetselier P.; Van Den Abbeele J. | |
| Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation | 2018 | Bruning U.; Morales-Rodriguez F.; Kalucka J.; Goveia J.; Taverna F.; Queiroz K.C.S.; Dubois C.; Cantelmo A.R.; Chen R.; Loroch S.; Timmerman E.; Caixeta V.; Bloch K.; Conradi L.-C.; Treps L.; Staes A.; Gevaert K.; Tee A.; Dewerchin M.; Semenkovich C.F.; Impens F.; Schilling B.; Verdin E.; Swinnen J.V.; Meier J.L.; Kulkarni R.A.; Sickmann A.; Ghesquiere B.; Schoonjans L.; Li X.; Mazzone M.; Carmeliet P. | |
| Metabolism and TAM functions—it takes two to tango | 2018 | Mazzone M.; Menga A.; Castegna A. | |
| Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis | 2018 | Kalucka J.; Bierhansl L.; Conchinha N.V.; Missiaen R.; Elia I.; Bruning U.; Scheinok S.; Treps L.; Cantelmo A.R.; Dubois C.; de Zeeuw P.; Goveia J.; Zecchin A.; Taverna F.; Morales-Rodriguez F.; Brajic A.; Conradi L.-C.; Schoors S.; Harjes U.; Vriens K.; Pilz G.-A.; Chen R.; Cubbon R.; Thienpont B.; Cruys B.; Wong B.W.; Ghesquiere B.; Dewerchin M.; De Bock K.; Sagaert X.; Jessberger S.; Jones E.A.V.; Gallez B.; Lambrechts D.; Mazzone M.; Eelen G.; Li X.; Fendt S.-M.; Carmeliet P. | |
| Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy | 2018 | Smeets D.; Miller I.S.; O'Connor D.P.; Das S.; Moran B.; Boeckx B.; Gaiser T.; Betge J.; Barat A.; Klinger R.; van Grieken N.C.T.; Cremolini C.; Prenen H.; Mazzone M.; Depreeuw J.; Bacon O.; Fender B.; Brady J.; Hennessy B.T.; McNamara D.A.; Kay E.; Verheul H.M.; Maarten N.; Gallagher W.M.; Murphy V.; Prehn J.H.M.; Koopman M.; Punt C.J.A.; Loupakis F.; Ebert M.P.A.; Ylstra B.; Lambrechts D.; Byrne A.T. | |
| Inhibition of prolyl hydroxylase domain proteins selectively enhances venous thrombus neovascularisation | 2018 | Grover S.P.; Saha P.; Humphries J.; Lyons O.T.; Patel A.S.; Serneels J.; Modarai B.; Mazzone M.; Smith A. | |
| Loss of Caveolin-1 in Metastasis-Associated Macrophages Drives Lung Metastatic Growth through Increased Angiogenesis | 2017 | Celus W.; Di Conza G.; Oliveira A.I.; Ehling M.; Costa B.M.; Wenes M.; Mazzone M. | |
| Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells | 2017 | Palmieri E.M.; Menga A.; Lebrun A.; Hooper D.C.; Butterfield D.A.; Mazzone M.; Castegna A. | |
| The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia | 2017 | Di Conza G.; Trusso Cafarello S.; Loroch S.; Mennerich D.; Deschoemaeker S.; Di Matteo M.; Ehling M.; Gevaert K.; Prenen H.; Zahedi R.P.; Sickmann A.; Kietzmann T.; Moretti F.; Mazzone M. | |
| Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis | 2017 | Martin-Perez R.; Yerbes R.; Mora-Molina R.; Cano-Gonzalez A.; Arribas J.; Mazzone M.; Lopez-Rivas A.; Palacios C. | |
| Retinoid X receptor suppresses a metastasis-promoting transcriptional program in myeloid cells via a ligand-insensitive mechanism | 2017 | Kiss M.; Czimmerer Z.; Nagy G.; Bieniasz-Krzywiec P.; Ehling M.; Pap A.; Poliska S.; Boto P.; Tzerpos P.; Horvath A.; Kolostyak Z.; Daniel B.; Szatmari I.; Mazzone M.; Nagy L. | |
| Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses | 2017 | Sadiku P.; Willson J.A.; Dickinson R.S.; Murphy F.; Harris A.J.; Lewis A.; Sammut D.; Mirchandani A.S.; Ryan E.; Watts E.R.; Thompson A.A.R.; Marriott H.M.; Dockrell D.H.; Taylor C.T.; Schneider M.; Maxwell P.H.; Chilvers E.R.; Mazzone M.; Moral V.; Pugh C.W.; Ratcliffe P.J.; Schofield C.J.; Ghesquiere B.; Carmeliet P.; Whyte M.K.B.; Walmsley S.R. | |
| Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium | 2017 | Reid S.E.; Kay E.J.; Neilson L.J.; Henze A.-T.; Serneels J.; McGhee E.J.; Dhayade S.; Nixon C.; Mackey J.B.G.; Santi A.; Swaminathan K.; Athineos D.; Papalazarou V.; Patella F.; Roman-Fernandez A.; ElMaghloob Y.; Hernandez-Fernaud J.R.; Adams R.H.; Ismail S.; Bryant D.M.; Salmeron-Sanchez M.; Machesky L.M.; Carlin L.M.; Blyth K.; Mazzone M.; Zanivan S. | |
| α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming | 2017 | Liu P.-S.; Wang H.; Li X.; Chao T.; Teav T.; Christen S.; DI Conza G.; Cheng W.-C.; Chou C.-H.; Vavakova M.; Muret C.; Debackere K.; Mazzone M.; Huang H.-D.; Fendt S.-M.; Ivanisevic J.; Ho P.-C. | |
| Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis | 2017 | Palmieri E.M.; Menga A.; Martin-Perez R.; Quinto A.; Riera-Domingo C.; De Tullio G.; Hooper D.C.; Lamers W.H.; Ghesquiere B.; McVicar D.W.; Guarini A.; Mazzone M.; Castegna A. | |
| Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism | 2017 | Thompson A.A.R.; Dickinson R.S.; Murphy F.; Thomson J.P.; Marriott H.M.; Tavares A.; Willson J.; Williams L.; Lewis A.; Mirchandani A.; Coelho P.D.S.; Doherty C.; Ryan E.; Watts E.; Morton N.M.; Forbes S.; Stimson R.H.; Hameed A.G.; Arnold N.; Preston J.A.; Lawrie A.; Finisguerra V.; Mazzone M.; Sadiku P.; Goveia J.; Taverna F.; Carmeliet P.; Foster S.J.; Chilvers E.R.; Cowburn A.S.; Dockrell D.H.; Johnson R.S.; Meehan R.R.; Whyte M.K.B.; Walmsley S.R. | |
| Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth | 2017 | Mathivet T.; Bouleti C.; Van Woensel M.; Stanchi F.; Verschuere T.; Phng L.-K.; Dejaegher J.; Balcer M.; Matsumoto K.; Georgieva P.B.; Belmans J.; Sciot R.; Stockmann C.; Mazzone M.; De Vleeschouwer S.; Gerhardt H. |
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