Sfoglia per Autore
Genetic and expression analysis of MET, MACC1 and HGF in metastatic colorectal cancer: Response to Met inhibition in patient xenografts and pathological correlations
2011-01-01 Francesco Galimi; Davide Torti; Francesco Sassi; Claudio Isella; Davide Corà; Stefania Gastaldi; Dario Ribero; Andrea Muratore; Paolo Massucco; Dimitrios Siatis; Gianluca Paraluppi; Federica Gonella; Francesca Maione; Alberto Pisacane; Ezio David; Bruno Torchio; Mauro Risio; Mauro Salizzoni; Lorenzo Capussotti; Tim Perera; Enzo Medico; M.F. Di Renzo; Paolo M. Comoglio; Livio Trusolino*; Andrea Bertotti* (*Co-Senior Authors)
A molecularly annotated platform of patient-derived xenografts (‘xenopatients’) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer
2011-01-01 Bertotti A; Migliardi G; Galimi F; Sassi F; Torti D; Isella C; Corà D; Di Nicolantonio F; Buscarino M; Petti C; Ribero D; Russolillo N; Muratore A; Massucco P; Pisacane A; Molinaro L; Valtorta E; Sartore-Bianchi A; Risio M; Capussotti L; Gambacorta M; Siena S; Medico E; Sapino A; Marsoni S; Comoglio PM; Bardelli A†; Trusolino L† (†Co-Senior authors)
MET SIGNALING REGULATES GROWTH, REPOPULATING POTENTIAL AND BASAL CELL-FATE COMMITMENT OF MAMMARY LUMINAL PROGENITORS: IMPLICATIONS FOR BASAL-LIKE BREAST CANCER.
2012-01-01 Paolo Accornero; Stefania Gastaldi; Francesco Sassi; Davide Torti; Silvia Miretti; Eugenio Martignani; Mario Baratta; Matthew J Smalley; Andrea Bertotti; Livio Trusolino
A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors.
2012-01-01 D. Torti;F. Sassi;F. Galimi;S. Gastaldi;T. Perera;P. M. Comoglio;L. Trusolino*; A. Bertotti* (*Co-Senior Authors)
LAS: A Software Platform to Support Oncological Data Management
2012-01-01 Baralis E; Bertotti A; Fiori A; Grand A.
INHIBITION OF MEK AND PI3K/MTOR SUPPRESSES TUMOR GROWTH BUT DOES NOT CAUSE TUMOR REGRESSION IN PATIENT-DERIVED XENOGRAFTS OF RAS-MUTANT COLORECTAL CARCINOMAS
2012-01-01 Giorgia Migliardi; Francesco Sassi; Davide Torti; Francesco Galimi; Eugenia R. Zanella; Michela Buscarino; Dario Ribero; Andrea Muratore; Paolo Massucco; Alberto Pisacane; Mauro Risio; Lorenzo Capussotti; Silvia Marsoni; Federica Di Nicolantonio; Alberto Bardelli; Paolo M. Comoglio; Livio Trusolino*; Andrea Bertotti* (*Co-Senior Authors)
Compensatory pathways in oncogenic kinase signaling and resistance to targeted therapies: Six degrees of separation
2012-01-01 Trusolino L; Bertotti A
MACC1 mRNA levels predict cancer recurrence after resection of colorectal cancer liver metastases.
2013-01-01 Isella C;Mellano A;Galimi F;Petti C;Capussotti L;De Simone M;Bertotti A;Medico E;Muratore A
Animal research: Temper Italy's strict lab-animal law.
2013-01-01 Trusolino L;Bertotti A
Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer.
2013-01-01 S. Gastaldi; F. Sassi; P. Accornero; D. Torti; F. Galimi; G. Migliardi; G. Molyneux; T. Perera; P. M. Comoglio; C. Boccaccio; M. J. Smalley; A. Bertotti*; L. Trusolino* (*Co-Senior Authors)
Amplification of the MET Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer.
2013-01-01 Bardelli A*;Corso S*;Bertotti A*;Hobor S;Valtorta E;Siravegna G;Sartore-Bianchi A;Scala E;Cassingena A;Zecchin D;Apicella M;Migliardi G;Galimi F;Lauricella C;Zanon C;Perera T;Veronese S;Corti G;Amatu A;Gambacorta M;Diaz LA Jr;Sausen M;Velculescu VE;Comoglio P;Trusolino L;Di Nicolantonio F;Giordano S;Siena S (*Co-First Authors)
From Bench to Bedside: Does Preclinical Practice in Translational Oncology Need Some Rebuilding?
2013-01-01 A. Bertotti;L. Trusolino
Intrinsic Resistance to MEK Inhibition in KRAS Mutant Lung and Colon Cancer through Transcriptional Induction of ERBB3.
2014-01-01 Sun C;Hobor S;Bertotti A;Zecchin D;Huang S;Galimi F;Cottino F;Prahallad A;Grernrum W;Tzani A;Schlicker A;Wessels LF;Smit EF;Thunnissen E;Halonen P;Lieftink C;Beijersbergen RL;Di Nicolantonio F;Bardelli A;Trusolino L;Bernards R
Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models.
2014-01-01 Peraldo-Neia C;Cavalloni G;Soster M;Gammaitoni L;Marchiò S;Sassi F;Trusolino L;Bertotti A;Medico E;Capussotti L;Aglietta M;Leone F
NOTCH3 SIGNALING REGULATES MUSASHI-1 EXPRESSION IN METASTATIC COLORECTAL CANCER CELLS.
2014-01-01 Pasto A;Serafin V;Pilotto G;Lago C;Bellio C;Trusolino L;Bertotti A;Hoey T;Plateroti M;Esposito G;Pinazza M;Agostini M;Nitti D;Amadori A;Indraccolo S
MET dysregulation is a hallmark of aggressive disease in multiple myeloma patients
2014-01-01 Rocci A;Gambella M;Aschero S;Baldi I;Trusolino L;Cavallo F;Gay F;Larocca A;Magarotto V;Omedè P;Isaia G;Bertotti A;Liberati AM;Catalano L;De Rosa L;Musto P;Vallone R;Falcone A;Drandi D;Ladetto M;Comoglio PM;Boccadoro M;Palumbo A
Cytokine-induced killer cells eradicate bone and soft-tissue sarcomas.
2014-01-01 Sangiolo D; Mesiano G; Gammaitoni L; Leuci V; Todorovic M; Giraudo L; Cammarata C; Dell'aglio C; D'Ambrosio L; Pisacane A; Sarotto I; Miano S; Ferrero I; Carnevale-Schianca F; Pignochino Y; Sassi F; Bertotti A; Piacibello W; Fagioli F; Aglietta M; Grignani G.
Microenvironment-derived HGF overcomes genetically determined sensitivity to anti-MET drugs.
2014-01-01 Pennacchietti S;Cazzanti M;Bertotti A;Rideout WM ;Han M;Gyuris J;Perera T;Comoglio PM;Trusolino L;Michieli P
MET signaling in colon cancer stem-like cells blunts the therapeutic response to EGFR inhibitors.
2014-01-01 Luraghi P;Reato G;Cipriano E;Sassi F;Orzan F;Bigatto V;De Bacco F;Menietti E;Han M;Rideout WM;Perera T;Bertotti A;Trusolino L;Comoglio PM;Boccaccio C
Sustained Inhibition of HER3 and EGFR Is Necessary to Induce Regression of HER2-Amplified Gastrointestinal Carcinomas
2015-01-01 Leto, Simonetta M.; Sassi, Francesco; Catalano, Irene; Torri, Valter; Migliardi, Giorgia; Zanella, Eugenia R.; Throsby, Mark; Bertotti, Andrea; Trusolino, Livio
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Genetic and expression analysis of MET, MACC1 and HGF in metastatic colorectal cancer: Response to Met inhibition in patient xenografts and pathological correlations | 2011 | Francesco Galimi; Davide Torti; Francesco Sassi; Claudio Isella; Davide Corà; Stefania Gastaldi; Dario Ribero; Andrea Muratore; Paolo Massucco; Dimitrios Siatis; Gianluca Paraluppi; Federica Gonella; Francesca Maione; Alberto Pisacane; Ezio David; Bruno Torchio; Mauro Risio; Mauro Salizzoni; Lorenzo Capussotti; Tim Perera; Enzo Medico; M.F. Di Renzo; Paolo M. Comoglio; Livio Trusolino*; Andrea Bertotti* (*Co-Senior Authors) | |
| A molecularly annotated platform of patient-derived xenografts (‘xenopatients’) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer | 2011 | Bertotti A; Migliardi G; Galimi F; Sassi F; Torti D; Isella C; Corà D; Di Nicolantonio F; Buscarino M; Petti C; Ribero D; Russolillo N; Muratore A; Massucco P; Pisacane A; Molinaro L; Valtorta E; Sartore-Bianchi A; Risio M; Capussotti L; Gambacorta M; Siena S; Medico E; Sapino A; Marsoni S; Comoglio PM; Bardelli A†; Trusolino L† (†Co-Senior authors) | |
| MET SIGNALING REGULATES GROWTH, REPOPULATING POTENTIAL AND BASAL CELL-FATE COMMITMENT OF MAMMARY LUMINAL PROGENITORS: IMPLICATIONS FOR BASAL-LIKE BREAST CANCER. | 2012 | Paolo Accornero; Stefania Gastaldi; Francesco Sassi; Davide Torti; Silvia Miretti; Eugenio Martignani; Mario Baratta; Matthew J Smalley; Andrea Bertotti; Livio Trusolino | |
| A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors. | 2012 | D. Torti;F. Sassi;F. Galimi;S. Gastaldi;T. Perera;P. M. Comoglio;L. Trusolino*; A. Bertotti* (*Co-Senior Authors) | |
| LAS: A Software Platform to Support Oncological Data Management | 2012 | Baralis E; Bertotti A; Fiori A; Grand A. | |
| INHIBITION OF MEK AND PI3K/MTOR SUPPRESSES TUMOR GROWTH BUT DOES NOT CAUSE TUMOR REGRESSION IN PATIENT-DERIVED XENOGRAFTS OF RAS-MUTANT COLORECTAL CARCINOMAS | 2012 | Giorgia Migliardi; Francesco Sassi; Davide Torti; Francesco Galimi; Eugenia R. Zanella; Michela Buscarino; Dario Ribero; Andrea Muratore; Paolo Massucco; Alberto Pisacane; Mauro Risio; Lorenzo Capussotti; Silvia Marsoni; Federica Di Nicolantonio; Alberto Bardelli; Paolo M. Comoglio; Livio Trusolino*; Andrea Bertotti* (*Co-Senior Authors) | |
| Compensatory pathways in oncogenic kinase signaling and resistance to targeted therapies: Six degrees of separation | 2012 | Trusolino L; Bertotti A | |
| MACC1 mRNA levels predict cancer recurrence after resection of colorectal cancer liver metastases. | 2013 | Isella C;Mellano A;Galimi F;Petti C;Capussotti L;De Simone M;Bertotti A;Medico E;Muratore A | |
| Animal research: Temper Italy's strict lab-animal law. | 2013 | Trusolino L;Bertotti A | |
| Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer. | 2013 | S. Gastaldi; F. Sassi; P. Accornero; D. Torti; F. Galimi; G. Migliardi; G. Molyneux; T. Perera; P. M. Comoglio; C. Boccaccio; M. J. Smalley; A. Bertotti*; L. Trusolino* (*Co-Senior Authors) | |
| Amplification of the MET Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer. | 2013 | Bardelli A*;Corso S*;Bertotti A*;Hobor S;Valtorta E;Siravegna G;Sartore-Bianchi A;Scala E;Cassingena A;Zecchin D;Apicella M;Migliardi G;Galimi F;Lauricella C;Zanon C;Perera T;Veronese S;Corti G;Amatu A;Gambacorta M;Diaz LA Jr;Sausen M;Velculescu VE;Comoglio P;Trusolino L;Di Nicolantonio F;Giordano S;Siena S (*Co-First Authors) | |
| From Bench to Bedside: Does Preclinical Practice in Translational Oncology Need Some Rebuilding? | 2013 | A. Bertotti;L. Trusolino | |
| Intrinsic Resistance to MEK Inhibition in KRAS Mutant Lung and Colon Cancer through Transcriptional Induction of ERBB3. | 2014 | Sun C;Hobor S;Bertotti A;Zecchin D;Huang S;Galimi F;Cottino F;Prahallad A;Grernrum W;Tzani A;Schlicker A;Wessels LF;Smit EF;Thunnissen E;Halonen P;Lieftink C;Beijersbergen RL;Di Nicolantonio F;Bardelli A;Trusolino L;Bernards R | |
| Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models. | 2014 | Peraldo-Neia C;Cavalloni G;Soster M;Gammaitoni L;Marchiò S;Sassi F;Trusolino L;Bertotti A;Medico E;Capussotti L;Aglietta M;Leone F | |
| NOTCH3 SIGNALING REGULATES MUSASHI-1 EXPRESSION IN METASTATIC COLORECTAL CANCER CELLS. | 2014 | Pasto A;Serafin V;Pilotto G;Lago C;Bellio C;Trusolino L;Bertotti A;Hoey T;Plateroti M;Esposito G;Pinazza M;Agostini M;Nitti D;Amadori A;Indraccolo S | |
| MET dysregulation is a hallmark of aggressive disease in multiple myeloma patients | 2014 | Rocci A;Gambella M;Aschero S;Baldi I;Trusolino L;Cavallo F;Gay F;Larocca A;Magarotto V;Omedè P;Isaia G;Bertotti A;Liberati AM;Catalano L;De Rosa L;Musto P;Vallone R;Falcone A;Drandi D;Ladetto M;Comoglio PM;Boccadoro M;Palumbo A | |
| Cytokine-induced killer cells eradicate bone and soft-tissue sarcomas. | 2014 | Sangiolo D; Mesiano G; Gammaitoni L; Leuci V; Todorovic M; Giraudo L; Cammarata C; Dell'aglio C; D'Ambrosio L; Pisacane A; Sarotto I; Miano S; Ferrero I; Carnevale-Schianca F; Pignochino Y; Sassi F; Bertotti A; Piacibello W; Fagioli F; Aglietta M; Grignani G. | |
| Microenvironment-derived HGF overcomes genetically determined sensitivity to anti-MET drugs. | 2014 | Pennacchietti S;Cazzanti M;Bertotti A;Rideout WM ;Han M;Gyuris J;Perera T;Comoglio PM;Trusolino L;Michieli P | |
| MET signaling in colon cancer stem-like cells blunts the therapeutic response to EGFR inhibitors. | 2014 | Luraghi P;Reato G;Cipriano E;Sassi F;Orzan F;Bigatto V;De Bacco F;Menietti E;Han M;Rideout WM;Perera T;Bertotti A;Trusolino L;Comoglio PM;Boccaccio C | |
| Sustained Inhibition of HER3 and EGFR Is Necessary to Induce Regression of HER2-Amplified Gastrointestinal Carcinomas | 2015 | Leto, Simonetta M.; Sassi, Francesco; Catalano, Irene; Torri, Valter; Migliardi, Giorgia; Zanella, Eugenia R.; Throsby, Mark; Bertotti, Andrea; Trusolino, Livio |
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