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Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis. 2001 ATZORI C ;GHETTI B ;PIVA R ;SRINIVASAN AN ;ZOLO P ;DELISLE MB ;MIRRA SS ;MIGHELI A
In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation. 2002 PIVA R ;LIU J ;CHIARLE R ;PODDA A ;PAGANO M ;INGHIRAMI G
Inverse relationship between p27/Kip.1 and the F-box protein Skp2 in human astrocytic gliomas by immunohistochemistry and Western blot. 2002 SCHIFFER D ;CAVALLA P ;FIANO V ;GHIMENTI C ;PIVA R
Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death 2002 ZAMO A; R. CHIARLE; PIVA R; HOWES J; FAN Y; CHILOSI M; LEVY DE; INGHIRAMI G.
S-phase kinase-associated protein 2 expression in non-Hodgkin's lymphoma inversely correlates with p27 expression and defines cells in S phase 2002 CHIARLE R; FAN Y; PIVA R; BOGGINO H; SKOLNIK J; NOVERO D; PALESTRO G; DE WOLF-PEETERS C; CHILOSI M; PAGANO M; INGHIRAMI G
NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors. 2003 CHIARLE R; GONG JZ; GUASPARRI I; PESCI A; CAI H; LIU J; SIMMONS WJ; DHALL G; HOWES J; PIVA R; INGHIRAMI G
Activated p38MAPK is a novel component of the intracellular inclusions found in human amyotrophic lateral sclerosis and mutant SOD1 transgenic mice 2004 BENDOTTI C; ATZORI C; PIVA R; TORTAROLO M; STRONG MJ; DEBIASI S; MIGHELI A
Targeting oncogenic ALK by lentiviral small interfering RNA induces growth arrest and apoptosis of human Anaplastic Large Cell Lymphoma cells 2004 Piva R; Manazza AD; Taulli R; Ponzetto C; Chiarle R; Inghirami G
Targeting oncogenic ALK by stable small interfering RNA induces cell death of human Anaplastic Large Cell Lymphoma cells 2004 R Piva; A Manazza; R Taulli; C Ponzetto; R Chiarle; G Inghirami
CD30 expression in anaplastic large cell lymphomas is dependent on ALK tyrosine kinase activity via Stat3 phosphorylation and JunB upregulation 2005 Boccalatte F; Piva R; Manazza A; Palestro G; Chiarle R; Inghirami G
Targeting oncogenic ALK by lentiviral small interfering RNA induces growth arrest and apoptosis of human anaplastic large cell lymphoma cells 2005 Piva R; Manazza A; Taulli R; Ponzetto C; Simmons W; Chiarle R; Inghirami G
Identification of genomic and proteomic signatures in lymphomas by inducible shRNA 2005 R Piva; E Pellegrino; M Mattioli; C Voena; C Conte; F Boccalatte; C Ambrogio; A Manazza; A Neri; R Chiarle; G Inghirami
15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis in human malignant B cells: an effect associated with inhibition of NF-kappa B activity and down-regulation of antiapoptotic proteins 2005 PIVA R; GIANFERRETTI P; CIUCCI A; TAULLI R; BELARDO G; SANTORO MG
p130Cas mediates the transforming properties of the anaplastic lymphoma kinase 2005 AMBROGIO C; VOENA C; MANAZZA AD; PIVA R; RIERA L; BARBERIS L; COSTA C; TARONE G; DEFILIPPI P; HIRSCH E; ERBA EB; MOHAMMED S; JENSEN ON; PALESTRO G; INGHIRAMI G; CHIARLE R.
New and old functions of STAT3: a pivotal target for individualized treatment of cancer 2005 INGHIRAMI G; CHIARLE R; SIMMONS WJ; PIVA R; SCHLESSINGER K; LEVY DE.
Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes 2006 PIVA R; PELLEGRINO E; MATTIOLI M; AGNELLI L; LOMBARDI L; BOCCALATTE F; COSTA; G; RUGGERI BA; CHENG M; CHIARLE R; PALESTRO G; NERI A; INGHIRAMI G
NF-kappaB: a stress-regulated switch for cell survival 2006 PIVA R ;BELARDO G; SANTORO MG
Induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: role of the IkappaB kinase/nuclear factor-kappaB pathway 2006 CIUCCI A; GIANFERRETTI P; PIVA R; GUYOT T; SNAPE TJ; ROBERTS SM; SANTORO MG
Ablation of oncogenic ALK is a viable therapeutic approach fAblation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas 2006 PIVA R; CHIARLE R; MANAZZA AD; TAULLI R; SIMMONS W; AMBROGIO C; D'ESCAMARD V; PELLEGRINO E; PONZETTO C; PALESTRO G; INGHIRAMI G
Dissection of critical pathways instrumental for Anaplastic Lymphoma Kinase transformation 2007 Piva R; E Pellegrino; V Grosso; AD Manazza; F Boccalatte; V Poli; A Neri; R Chiarle; G Inghirami
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