LUPO, Barbara
LUPO, Barbara
ONCOLOGIA
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype
2020-01-01 Lupo, Barbara; Sassi, Francesco; Pinnelli, Marika; Galimi, Francesco; Zanella, Eugenia R.; Vurchio, Valentina; Migliardi, Giorgia; Gagliardi, Paolo Armando; Puliafito, Alberto; Manganaro, Daria; Luraghi, Paolo; Kragh, Michael; Pedersen, Mikkel W.; Horak, Ivan D.; Boccaccio, Carla; Medico, Enzo; Primo, Luca; Nichol, Daniel; Spiteri, Inmaculada; Heide, Timon; Vatsiou, Alexandra; Graham, Trevor A.; Élez, Elena; Argiles, Guillem; Nuciforo, Paolo; Sottoriva, Andrea; Dienstmann, Rodrigo; Pasini, Diego; Grassi, Elena; Isella, Claudio; Bertotti, Andrea; Trusolino, Livio
Expression of sialidase Neu2 in leukemic K562 cells induces apoptosis by impairing Bcr-Abl/Src kinases signaling
2007-01-01 Tringali, Cristina; Lupo, Barbara; Anastasia, Luigi; Papini, Nadia; Monti, Eugenio; Bresciani, Roberto; Tettamanti, Guido; Venerando, Bruno
Genome-wide CRISPR screens reveal Hippo pathway activation as a resistance mechanism in BRAF mutant colon cancer
2021-01-01 Brammeld, JS; Thorpe, H; Garcia, MA; Price, S; Young, J; Pfeifer, M; Lupo, B; Yusa, K; Trusolino, L; Garnett, M; Bertotti, A; Bakal, C; McDermott, U
IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies.
2015-01-01 Zanella ER;Galimi F;Sassi F;Migliardi G;Cottino F;Leto SM;Lupo B;Erriquez J;Isella C;Comoglio PM;Medico E;Tejpar S;Budinsk E;Trusolino L*;Bertotti A*(*Co-Senior e Corresponding Authors)
Inhibition of polyADP-ribosylation in cancer: Old and new paradigms revisited.
2014-01-01 Lupo B;Trusolino L
Multi-label transcriptional classification of colorectal cancer reflects tumor cell population heterogeneity
2023-01-01 Cascianelli, Silvia; Barbera, Chiara; Ulla, Alexandra Ambra; Grassi, Elena; Lupo, Barbara; Pasini, Diego; Bertotti, Andrea; Trusolino, Livio; Medico, Enzo; Isella, Claudio; Masseroli, Marco
NEU4L sialidase overexpression promotes β-catenin signaling in neuroblastoma cells, enhancing stem-like malignant cell growth
2012-01-01 Tringali, Cristina; Cirillo, Federica; Lamorte, Giuseppe; Papini, Nadia; Anastasia, Luigi; Lupo, Barbara; Silvestri, Ilaria; Tettamanti, Guido; Venerando, Bruno
Phosphoproteomics of patient-derived xenographs identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer
2023-01-01 Beekhof, Robin; Bertotti, Andrea; Böttger, Franziska; Vurchio, Valentina; Cottino, Francesca; Zanella, Eugenia R; Migliardi, Giorgia; Viviani, Marco; Grassi, Elena; Lupo, Barbara; Henneman, Alex A; Knol, Jaco C; Pham, Thang V; de Goeij-de Haas, Richard; Piersma, Sander R; Labots, Mariette; Verheul, Henk M W; Trusolino, Livio; Jimenez, Connie R
Rebound effects caused by withdrawal of MET Kinase inhibitor are quenched by a MET Therapeutic antibody
2016-01-01 Pupo, Emanuela; Ducano, Nadia; Lupo, Barbara; Vigna, Elisa; Avanzato, Daniele; Perera, Timothy; Trusolino, Livio; Lanzetti, Letizia; Comoglio, Paolo M.
Repurposed AT9283 triggers anti-tumoral effects by targeting MKK3 oncogenic functions in Colorectal Cancer
2024-01-01 Piastra, Valentina; Ganci, Federica; Sacconi, Andrea; Pranteda, Angelina; Allegretti, Matteo; Bernardini, Roberta; Serra, Martina; Lupo, Barbara; Dell'Aquila, Emanuela; Ferretti, Gianluigi; Pescarmona, Edoardo; Bartolazzi, Armando; Blandino, Giovanni; Trusolino, Livio; Bossi, Gianluca
Sialidase NEU4 is involved in glioblastoma stem cell survival
2014-01-01 Silvestri, I; Testa, F; Zappasodi, R; Cairo, C W; Zhang, Y; Lupo, B; Galli, R; Di Nicola, M; Venerando, B; Tringali, C
Silencing of membrane-associated sialidase Neu3 diminishes apoptosis resistance and triggers megakaryocytic differentiation of chronic myeloid leukemic cells K562 through the increase of ganglioside GM3
2009-01-01 Tringali, C; Lupo, B; Cirillo, F; Papini, N; Anastasia, L; Lamorte, G; Colombi, P; Bresciani, R; Monti, E; Tettamanti, G; Venerando, B
Tankyrase inhibition impairs directional migration and invasion of lung cancer cells by affecting microtubule dynamics and polarity signals
2016-01-01 Lupo, Barbara; Vialard, Jorge; Sassi, Francesco; Angibaud, Patrick; Puliafito, Alberto; Pupo, Emanuela; Lanzetti, Letizia; Comoglio, Paolo M.; Bertotti, Andrea; Trusolino, Livio
The genomic landscape of response to EGFR blockade in colorectal cancer
2015-01-01 Bertotti, Andrea*; Papp, Eniko; Jones, Siân; Adleff, Vilmos; Anagnostou, Valsamo; Lupo, Barbara; Sausen, Mark; Phallen, Jillian; Hruban, Carolyn A.; Tokheim, Collin; Niknafs, Noushin; Nesselbush, Monica; Lytle, Karli; Sassi, Francesco; Cottino, Francesca; Migliardi, Giorgia; Zanella, Eugenia R.; Ribero, Dario; Russolillo, Nadia; Mellano, Alfredo; Muratore, Andrea; Paraluppi, Gianluca; Salizzoni, Mauro; Marsoni, Silvia; Kragh, Michael; Lantto, Johan; Cassingena, Andrea; Li, Qing Kay; Karchin, Rachel; Scharpf, Robert; Sartore-Bianchi, Andrea; Siena, Salvatore; Diaz, Luis A.; Trusolino, Livio*; Velculescu, Victor E*. (*Co-Senior e Corresponding Authors)
The plasma membrane sialidase NEU3 regulates the malignancy of renal carcinoma cells by controlling β1 integrin internalization and recycling
2012-01-01 Tringali, Cristina; Lupo, Barbara; Silvestri, Ilaria; Papini, Nadia; Anastasia, Luigi; Tettamanti, Guido; Venerando, Bruno
XENTURION is a population-level multidimensional resource of xenografts and tumoroids from metastatic colorectal cancer patients
2024-01-01 Leto, Simonetta M.; Grassi, Elena; Avolio, Marco; Vurchio, Valentina; Cottino, Francesca; Ferri, Martina; Zanella, Eugenia R.; Borgato, Sofia; Corti, Giorgio; di Blasio, Laura; Somale, Desiana; Vara-Messler, Marianela; Galimi, Francesco; Sassi, Francesco; Lupo, Barbara; Catalano, Irene; Pinnelli, Marika; Viviani, Marco; Sperti, Luca; Mellano, Alfredo; Ferrero, Alessandro; Zingaretti, Caterina C.; Puliafito, Alberto; Primo, Luca; Bertotti, Andrea; Trusolino, Livio
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype | 2020 | Lupo, Barbara; Sassi, Francesco; Pinnelli, Marika; Galimi, Francesco; Zanella, Eugenia R.; Vurchio, Valentina; Migliardi, Giorgia; Gagliardi, Paolo Armando; Puliafito, Alberto; Manganaro, Daria; Luraghi, Paolo; Kragh, Michael; Pedersen, Mikkel W.; Horak, Ivan D.; Boccaccio, Carla; Medico, Enzo; Primo, Luca; Nichol, Daniel; Spiteri, Inmaculada; Heide, Timon; Vatsiou, Alexandra; Graham, Trevor A.; Élez, Elena; Argiles, Guillem; Nuciforo, Paolo; Sottoriva, Andrea; Dienstmann, Rodrigo; Pasini, Diego; Grassi, Elena; Isella, Claudio; Bertotti, Andrea; Trusolino, Livio | |
| Expression of sialidase Neu2 in leukemic K562 cells induces apoptosis by impairing Bcr-Abl/Src kinases signaling | 2007 | Tringali, Cristina; Lupo, Barbara; Anastasia, Luigi; Papini, Nadia; Monti, Eugenio; Bresciani, Roberto; Tettamanti, Guido; Venerando, Bruno | |
| Genome-wide CRISPR screens reveal Hippo pathway activation as a resistance mechanism in BRAF mutant colon cancer | 2021 | Brammeld, JS; Thorpe, H; Garcia, MA; Price, S; Young, J; Pfeifer, M; Lupo, B; Yusa, K; Trusolino, L; Garnett, M; Bertotti, A; Bakal, C; McDermott, U | |
| IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies. | 2015 | Zanella ER;Galimi F;Sassi F;Migliardi G;Cottino F;Leto SM;Lupo B;Erriquez J;Isella C;Comoglio PM;Medico E;Tejpar S;Budinsk E;Trusolino L*;Bertotti A*(*Co-Senior e Corresponding Authors) | |
| Inhibition of polyADP-ribosylation in cancer: Old and new paradigms revisited. | 2014 | Lupo B;Trusolino L | |
| Multi-label transcriptional classification of colorectal cancer reflects tumor cell population heterogeneity | 2023 | Cascianelli, Silvia; Barbera, Chiara; Ulla, Alexandra Ambra; Grassi, Elena; Lupo, Barbara; Pasini, Diego; Bertotti, Andrea; Trusolino, Livio; Medico, Enzo; Isella, Claudio; Masseroli, Marco | |
| NEU4L sialidase overexpression promotes β-catenin signaling in neuroblastoma cells, enhancing stem-like malignant cell growth | 2012 | Tringali, Cristina; Cirillo, Federica; Lamorte, Giuseppe; Papini, Nadia; Anastasia, Luigi; Lupo, Barbara; Silvestri, Ilaria; Tettamanti, Guido; Venerando, Bruno | |
| Phosphoproteomics of patient-derived xenographs identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer | 2023 | Beekhof, Robin; Bertotti, Andrea; Böttger, Franziska; Vurchio, Valentina; Cottino, Francesca; Zanella, Eugenia R; Migliardi, Giorgia; Viviani, Marco; Grassi, Elena; Lupo, Barbara; Henneman, Alex A; Knol, Jaco C; Pham, Thang V; de Goeij-de Haas, Richard; Piersma, Sander R; Labots, Mariette; Verheul, Henk M W; Trusolino, Livio; Jimenez, Connie R | |
| Rebound effects caused by withdrawal of MET Kinase inhibitor are quenched by a MET Therapeutic antibody | 2016 | Pupo, Emanuela; Ducano, Nadia; Lupo, Barbara; Vigna, Elisa; Avanzato, Daniele; Perera, Timothy; Trusolino, Livio; Lanzetti, Letizia; Comoglio, Paolo M. | |
| Repurposed AT9283 triggers anti-tumoral effects by targeting MKK3 oncogenic functions in Colorectal Cancer | 2024 | Piastra, Valentina; Ganci, Federica; Sacconi, Andrea; Pranteda, Angelina; Allegretti, Matteo; Bernardini, Roberta; Serra, Martina; Lupo, Barbara; Dell'Aquila, Emanuela; Ferretti, Gianluigi; Pescarmona, Edoardo; Bartolazzi, Armando; Blandino, Giovanni; Trusolino, Livio; Bossi, Gianluca | |
| Sialidase NEU4 is involved in glioblastoma stem cell survival | 2014 | Silvestri, I; Testa, F; Zappasodi, R; Cairo, C W; Zhang, Y; Lupo, B; Galli, R; Di Nicola, M; Venerando, B; Tringali, C | |
| Silencing of membrane-associated sialidase Neu3 diminishes apoptosis resistance and triggers megakaryocytic differentiation of chronic myeloid leukemic cells K562 through the increase of ganglioside GM3 | 2009 | Tringali, C; Lupo, B; Cirillo, F; Papini, N; Anastasia, L; Lamorte, G; Colombi, P; Bresciani, R; Monti, E; Tettamanti, G; Venerando, B | |
| Tankyrase inhibition impairs directional migration and invasion of lung cancer cells by affecting microtubule dynamics and polarity signals | 2016 | Lupo, Barbara; Vialard, Jorge; Sassi, Francesco; Angibaud, Patrick; Puliafito, Alberto; Pupo, Emanuela; Lanzetti, Letizia; Comoglio, Paolo M.; Bertotti, Andrea; Trusolino, Livio | |
| The genomic landscape of response to EGFR blockade in colorectal cancer | 2015 | Bertotti, Andrea*; Papp, Eniko; Jones, Siân; Adleff, Vilmos; Anagnostou, Valsamo; Lupo, Barbara; Sausen, Mark; Phallen, Jillian; Hruban, Carolyn A.; Tokheim, Collin; Niknafs, Noushin; Nesselbush, Monica; Lytle, Karli; Sassi, Francesco; Cottino, Francesca; Migliardi, Giorgia; Zanella, Eugenia R.; Ribero, Dario; Russolillo, Nadia; Mellano, Alfredo; Muratore, Andrea; Paraluppi, Gianluca; Salizzoni, Mauro; Marsoni, Silvia; Kragh, Michael; Lantto, Johan; Cassingena, Andrea; Li, Qing Kay; Karchin, Rachel; Scharpf, Robert; Sartore-Bianchi, Andrea; Siena, Salvatore; Diaz, Luis A.; Trusolino, Livio*; Velculescu, Victor E*. (*Co-Senior e Corresponding Authors) | |
| The plasma membrane sialidase NEU3 regulates the malignancy of renal carcinoma cells by controlling β1 integrin internalization and recycling | 2012 | Tringali, Cristina; Lupo, Barbara; Silvestri, Ilaria; Papini, Nadia; Anastasia, Luigi; Tettamanti, Guido; Venerando, Bruno | |
| XENTURION is a population-level multidimensional resource of xenografts and tumoroids from metastatic colorectal cancer patients | 2024 | Leto, Simonetta M.; Grassi, Elena; Avolio, Marco; Vurchio, Valentina; Cottino, Francesca; Ferri, Martina; Zanella, Eugenia R.; Borgato, Sofia; Corti, Giorgio; di Blasio, Laura; Somale, Desiana; Vara-Messler, Marianela; Galimi, Francesco; Sassi, Francesco; Lupo, Barbara; Catalano, Irene; Pinnelli, Marika; Viviani, Marco; Sperti, Luca; Mellano, Alfredo; Ferrero, Alessandro; Zingaretti, Caterina C.; Puliafito, Alberto; Primo, Luca; Bertotti, Andrea; Trusolino, Livio |