DE SIMONE, Angela

DE SIMONE, Angela  

SCIENZA E TECNOLOGIA DEL FARMACO  

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Risultati 1 - 20 di 58 (tempo di esecuzione: 0.022 secondi).
Titolo Data di pubblicazione Autore(i) File
(±)- BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease 2021 Ismaili L.; Monnin J.; Etievant A.; Arribas R.L.; Viejo L.; Refouvelet B.; Soukup O.; Janockova J.; Hepnarova V.; Korabecny J.; Kucera T.; Jun D.; Andrys R.; Musilek K.; Baguet A.; Garcia-Frutos E.M.; De Simone A.; Andrisano V.; Bartolini M.; De Los Rios C.; Marco-Contelles J.; Haffen E.
- The role of Chromatography in Alzheimer’s Disease Drug Discovery 2017 Fiori J; De Simone A; Naldi M; Andrisano V
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease 2015 Prati Federica; De Simone Angela; Armirotti Andrea; Summa Maria; Pizzirani Daniela; Scarpelli Rita; Bertozzi Sine Mandrup; Perez Daniel I.; Andrisano Vincenza; Perez-Castillo Ana; Monti Barbara; Massenzio Francesca; Polito Letizia; Racchi Marco; Sabatino Piera; Bottegoni Giovanni; Martinez Ana; Cavalli Andrea; Bolognesi Maria L.
A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors 2019 Pérez-Areales, F Javier; Turcu, Andreea L; Barniol-Xicota, Marta; Pont, Caterina; Pivetta, Deborah; Espargaró, Alba; Bartolini, Manuela; De Simone, Angela; Andrisano, Vincenza; Pérez, Belén; Sabate, Raimon; Sureda, Francesc X; Vázquez, Santiago; Muñoz-Torrero, Diego
A patent review of butyrylcholinesterase inhibitors and reactivators 2010–2017 2018 Andrisano, Vincenza; Naldi, Marina; De Simone, Angela; Bartolini, Manuela
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation 2012 G. P. Chiriano; A. De Simone; F. Mancini; D. I. Perez; A. Cavalli; M. L. Bolognesi; G. Legname; A. Martinez; V. Andrisano; P. Carloni; M. Roberti
Advanced analytical methodologies in Alzheimer's disease drug discovery 2020 De Simone A.; Naldi M.; Tedesco D.; Bartolini M.; Davani L.; Andrisano V.
Amaryllidaceae Alkaloids as Potential Glycogen Synthase Kinase-3β Inhibitors 2018 Hulcová, Daniela; Breiterová, Kateřina; Siatka, Tomáš; Klímová, Kamila; Davani, Lara; Šafratová, Marcela; Hošťálková, Anna; De Simone, Angela; Andrisano, Vincenza; Cahlíková, Lucie
Amaryllidaceae alkaloids from Narcissus pseudonarcissus L. cv. Dutch Master as potential drugs in treatment of Alzheimer's disease 2019 Hulcova D.; Marikova J.; Korabecny J.; Hostalkova A.; Jun D.; Kunes J.; Chlebek J.; Opletal L.; De Simone A.; Novakova L.; Andrisano V.; Ruzicka A.; Cahlikova L.
Amyloid beta-Peptide 25-35 Self Assembly and Its Inhibition: A Model Undecapeptide System to Gain Atomistic and Secondary Structure Details of the Alzheimer's Disease Process and Treatment 2012 Naldi M.; Fiori J.; Pistolozzi M.; Drake A.F.; Bertucci C.; Wu R.; Mlynarczyk K.; Filipek S.; De Simone A.; Andrisano V.
Application of an ESI-QTOF method for the detailed characterization of GSK-3β inhibitors 2017 DE SIMONE, ANGELA; FIORI, JESSICA; NALDI, MARINA; D'URZO, ANNALISA; TUMIATTI, VINCENZO; MILELLI, ANDREA; ANDRISANO, VINCENZA
Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets 2016 Chlebek Jakub; De Simone Angela; Hoš͗álková Anna; Opletal Lubomír; Pérez Concepción; Pérez Daniel I.; Havlíková Lucie; Cahlíková Lucie; Andrisano Vincenza
Aβ1-42 peptide toxicity on neuronal cells: A lipidomic study 2022 Davani, Lara; Fu, Xiaoqing; De Simone, Angela; Li, Peng; Montanari, Serena; Lämmerhofer, Michael; Andrisano, Vincenza
Beta-secretase as a target for Alzheimer's disease drug discovery: an overview of in vitro methods for characterization of inhibitors 2011 F. Mancini; A. De Simone; V. Andrisano
Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6 2020 Perez-Areales F.J.; Garrido M.; Aso E.; Bartolini M.; De Simone A.; Espargaro A.; Ginex T.; Sabate R.; Perez B.; Andrisano V.; Puigoriol-Illamola D.; Pallas M.; Luque F.J.; Loza M.I.; Brea J.; Ferrer I.; Ciruela F.; Messeguer A.; Munoz-Torrero D.
Circular dichroism in drug discovery and development: an abridged review 2010 Bertucci C; Pistolozzi M; De Simone A.
Combined Methodologies for Determining In Vitro Bioavailability of Drugs and Prediction of In Vivo Bioequivalence From Pharmaceutical Oral Formulations 2021 De Simone A.; Davani L.; Montanari S.; Tumiatti V.; Avanessian S.; Testi F.; Andrisano V.
Design, synthesis and multitarget biological profiling of second-generation anti-Alzheimer rhein-huprine hybrids 2017 Pérez-Areales, Francisco Javier; Betari, Nibal; Viayna, Antonio; Pont, Caterina; Espargaró, Alba; Bartolini, Manuela; De Simone, Angela; Rinaldi Alvarenga, José Fernando; Pérez, Belén; Sabate, Raimon; Lamuela-Raventós, Rosa Maria; Andrisano, Vincenza; Luque, Francisco Javier; Muñoz-Torrero, Diego
Design, synthesis, in silico and in vitro screening of 1,2,4-thiadiazole analogues as non-peptide inhibitors of beta-secretase 2014 Gurjar AS; Andrisano V; De Simone A; Velingkar VS
Designing Dual Transglutaminase 2/Histone Deacetylase Inhibitors Effective at Halting Neuronal Death 2018 Manuela Basso; Huan Huan Chen; Debasmita Tripathy; Mariarosaria Conte; Kim Y. P. Apperley; Angela De Simone; Jeffrey W. Keillor; Rajiv Ratan; Angela Nebbioso; Federica Sarno; Lucia Altucci; Andrea Milelli.