GUGLIELMO, Stefano
GUGLIELMO, Stefano
SCIENZA E TECNOLOGIA DEL FARMACO
A multi-photoresponsive molecular-hybrid for dual-modal photoinactivation of cancer cells
2014-01-01 Aurore Fraix;Stefano Guglielmo;Venera Cardile;Adriana C. E. Graziano;Ruxandra Gref;Barbara Rolando;Roberta Fruttero;Alberto Gasco;Salvatore Sortino
A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity
2009-01-01 Stefano Guglielmo; Massimo Bertinaria; Barbara Rolando; Marco Crosetti; Roberta Fruttero; Vanessa Yardley; Simon L. Croft; Alberto Gasco
A Potent and Selective P-gp Modulator for Altering Multidrug Resistance Due to Pump Overexpression
2016-01-01 Guglielmo, Stefano; Contino, Marialessandra; Lazzarato, Loretta; Perrone, Maria Grazia; Blangetti, Marco; Fruttero, Roberta; Colabufo, Nicola Antonio
Amodiaquine analogues containing NO-donor substructures: Synthesis and their preliminary evaluation as potential tools in the treatment of cerebral malaria
2011-01-01 Massimo Bertinaria; Stefano Guglielmo; Barbara Rolando; Marta Giorgis; Cristina Aragno; Roberta Fruttero; Alberto Gasco; Silvia Parapini; Donatella Taramelli; Yuri C. Martins; Leonardo J.M. Carvalho
Anti-pseudomonas activity of 3-nitro-4-phenylfuroxan
2018-01-01 Orlandi, Viviana Teresa*; Bolognese, Fabrizio; Rolando, Barbara; Guglielmo, Stefano; Lazzarato, Loretta; Fruttero, Roberta
Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells
2019-01-01 Riganti, Chiara; Contino, Marialessandra*; Guglielmo, Stefano; Perrone, Maria G.; Salaroglio, Iris C.; Milosevic, Vladan; Giampietro, Roberta; Leonetti, Francesco; Rolando, Barbara; Lazzarato, Loretta; Colabufo, Nicola A.; Fruttero, Roberta
Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity
2017-01-01 Dos Santos Fernandes, Guilherme Felipe; De Souza, Paula Carolina; Moreno-viguri, Elsa; Santivaã±ez-veliz, Mery; Paucar, Rocio; Pã©rez-silanes, Silvia; Chegaev, Konstantin; Guglielmo, Stefano; Lazzarato, Loretta; Fruttero, Roberta; Man Chin, Chung; Da Silva, Patricia Bento; Chorilli, Marlus; Solcia, Mariana Cristina; Ribeiro, Camila Marãngolo; Silva, Caio Sander Paiva; Marino, Leonardo Biancolino; Bosquesi, Priscila Longhin; Hunt, Debbie M.; De Carvalho, Luiz Pedro S.; De Souza Costa, Carlos Alberto; Cho, Sang Hyun; Wang, Yuehong; Franzblau, Scott Gary; Pavan, Fernando Rogã©rio; Dos Santos, Jean Leandro
Direct introduction of cyano group on furoxan ring
2017-01-01 Annaratone, Lorenzo; Guglielmo, Stefano; Chegaev, Konstantin
Discovery of phenylsulfonylfuroxan derivatives as gamma globin inducers by histone acetylation
2018-01-01 Melo, Thais Regina Ferreira de; Kumkhaek, Chutima; Fernandes, Guilherme Felipe dos Santos; Lopes Pires, Maria Elisa; Chelucci, Rafael Consolin; Barbieri, Karina Pereira; Coelho, Fernanda; Capote, Ticiana Sidorenko de Oliveira; Lanaro, Carolina; Carlos, Iracilda Zeppone; Marcondes, Sisi; Chegaev, Konstantin; Guglielmo, Stefano; Fruttero, Roberta; Chung, Man Chin; Costa, Fernando Ferreira; Rodgers, Griffin P.; dos Santos, Jean Leandro*
DNA-targeted NO release photoregulated by green light
2020-01-01 Cristina Parisi, Aurore Fraix, Stefano Guglielmo, Francesca Spyrakis, Barbara Rolando, Loretta Lazzarato, Roberta Fruttero, Alberto Gasco, Salvatore Sortino
Doxorubicin-antioxidant multitarget drugs
2013-01-01 K Chegaev; C Riganti; B Rolando; L Lazzarato; E Gazzano; S Guglielmo; D Ghigo; R Fruttero; A Gasco
EFFICIENTLY TARGETING DRUG EFFLUX THROUGH MODULATION OF P-GLYCOPROTEIN ACTIVITY BY SMALL MOLECULES: DESIGN, BIOLOGICAL AND COMPUTATIONAL STUDY.
2019-01-01 Stefano Guglielmo, Marialessandra Contino, Chiara Riganti, Barbara Rolando, Loretta Lazzarato
Furoxan nitric oxide donors disperse Pseudomonas aeruginosa biofilms, accelerate growth, and repress pyoverdine production
2017-01-01 Poh, Wee Han; Barraud, Nicolas; Guglielmo, Stefano; Lazzarato, Loretta; Fruttero, Roberta; Rolando, Barbara; Rice, Scott A.
Furoxan-, alkylnitrate-derivatives and related compoundsas anti-trypanosomatid agents: Mechanism of action studies
2008-01-01 Lucia Boiani; Gabriela Aguirre; Mercedes González; Hugo Cerecetto; Agustina Chidichimo; Juan J. Cazzulo; Massimo Bertinaria; Stefano Guglielmo
gem-Dinitroalkyl Benzenes: A Novel Class of IOP-Lowering Agents for the Treatment of Ocular Hypertension
2017-01-01 Blangetti, Marco; Rolando, Barbara; Marini, Elisabetta; Chegaev, Konstantin; Guglielmo, Stefano; Lazzarato, Loretta; Laura, Lucarini; Emanuela, Masini; Fruttero, Roberta
Hybrid praziquantel-oxadiazole oxides with activity against Schistosoma mansoni.
2011-01-01 Daniela Cortese; Francesca Vottero; Stefano Guglielmo; Roberta Fruttero; Alberto Gasco; Latasha Day and David L. Williams.
Leishmanicidal Activity of Novel Synthetic Furoxan and Benzofuroxan Derivatives
2014-01-01 L. A. Dutra;L. De Almeida;T. G. Passalacqua;J. S. Reis;F. A. E. Torres;I. Martinez;R. G. Peccinini;C. Man Chin;K. Chegaev;S. Guglielmo;R. Fruttero;M. A. S. Graminha;J. L. Dos Santos
Light-Tunable Generation of Singlet Oxygen and Nitric Oxide with a Bichromophoric Molecular Hybrid: a Bimodal Approach to Killing Cancer Cells
2016-01-01 Fraix, Aurore; Blangetti, Marco; Guglielmo, Stefano; Lazzarato, Loretta; Marino, Nino; Cardile, Venera; Graziano, Adriana C.E.; Manet, Ilse; Fruttero, Roberta; Gasco, Alberto; Sortino, Salvatore
Mitochondrial delivery of phenol substructure triggers mitochondrial depolarization and apoptosis of cancer cells
2018-01-01 Gazzano, Elena; Lazzarato, Loretta; Rolando, Barbara; Kopecka, Joanna; Guglielmo, Stefano; Costamagna, Costanzo; Chegaev, Konstantin*; Riganti, Chiara
Molecular dynamics simulations reveal the determinants of cyclin-dependent kinase 2 inhibition by 5-nitrosopyrimidine derivatives
2019-01-01 Guglielmo S.; Cortese D.; Cano C.; Fruttero R.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A multi-photoresponsive molecular-hybrid for dual-modal photoinactivation of cancer cells | 2014 | Aurore Fraix;Stefano Guglielmo;Venera Cardile;Adriana C. E. Graziano;Ruxandra Gref;Barbara Rolando;Roberta Fruttero;Alberto Gasco;Salvatore Sortino | |
| A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity | 2009 | Stefano Guglielmo; Massimo Bertinaria; Barbara Rolando; Marco Crosetti; Roberta Fruttero; Vanessa Yardley; Simon L. Croft; Alberto Gasco | |
| A Potent and Selective P-gp Modulator for Altering Multidrug Resistance Due to Pump Overexpression | 2016 | Guglielmo, Stefano; Contino, Marialessandra; Lazzarato, Loretta; Perrone, Maria Grazia; Blangetti, Marco; Fruttero, Roberta; Colabufo, Nicola Antonio | |
| Amodiaquine analogues containing NO-donor substructures: Synthesis and their preliminary evaluation as potential tools in the treatment of cerebral malaria | 2011 | Massimo Bertinaria; Stefano Guglielmo; Barbara Rolando; Marta Giorgis; Cristina Aragno; Roberta Fruttero; Alberto Gasco; Silvia Parapini; Donatella Taramelli; Yuri C. Martins; Leonardo J.M. Carvalho | |
| Anti-pseudomonas activity of 3-nitro-4-phenylfuroxan | 2018 | Orlandi, Viviana Teresa*; Bolognese, Fabrizio; Rolando, Barbara; Guglielmo, Stefano; Lazzarato, Loretta; Fruttero, Roberta | |
| Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells | 2019 | Riganti, Chiara; Contino, Marialessandra*; Guglielmo, Stefano; Perrone, Maria G.; Salaroglio, Iris C.; Milosevic, Vladan; Giampietro, Roberta; Leonetti, Francesco; Rolando, Barbara; Lazzarato, Loretta; Colabufo, Nicola A.; Fruttero, Roberta | |
| Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity | 2017 | Dos Santos Fernandes, Guilherme Felipe; De Souza, Paula Carolina; Moreno-viguri, Elsa; Santivaã±ez-veliz, Mery; Paucar, Rocio; Pã©rez-silanes, Silvia; Chegaev, Konstantin; Guglielmo, Stefano; Lazzarato, Loretta; Fruttero, Roberta; Man Chin, Chung; Da Silva, Patricia Bento; Chorilli, Marlus; Solcia, Mariana Cristina; Ribeiro, Camila Marãngolo; Silva, Caio Sander Paiva; Marino, Leonardo Biancolino; Bosquesi, Priscila Longhin; Hunt, Debbie M.; De Carvalho, Luiz Pedro S.; De Souza Costa, Carlos Alberto; Cho, Sang Hyun; Wang, Yuehong; Franzblau, Scott Gary; Pavan, Fernando Rogã©rio; Dos Santos, Jean Leandro | |
| Direct introduction of cyano group on furoxan ring | 2017 | Annaratone, Lorenzo; Guglielmo, Stefano; Chegaev, Konstantin | |
| Discovery of phenylsulfonylfuroxan derivatives as gamma globin inducers by histone acetylation | 2018 | Melo, Thais Regina Ferreira de; Kumkhaek, Chutima; Fernandes, Guilherme Felipe dos Santos; Lopes Pires, Maria Elisa; Chelucci, Rafael Consolin; Barbieri, Karina Pereira; Coelho, Fernanda; Capote, Ticiana Sidorenko de Oliveira; Lanaro, Carolina; Carlos, Iracilda Zeppone; Marcondes, Sisi; Chegaev, Konstantin; Guglielmo, Stefano; Fruttero, Roberta; Chung, Man Chin; Costa, Fernando Ferreira; Rodgers, Griffin P.; dos Santos, Jean Leandro* | |
| DNA-targeted NO release photoregulated by green light | 2020 | Cristina Parisi, Aurore Fraix, Stefano Guglielmo, Francesca Spyrakis, Barbara Rolando, Loretta Lazzarato, Roberta Fruttero, Alberto Gasco, Salvatore Sortino | |
| Doxorubicin-antioxidant multitarget drugs | 2013 | K Chegaev; C Riganti; B Rolando; L Lazzarato; E Gazzano; S Guglielmo; D Ghigo; R Fruttero; A Gasco | |
| EFFICIENTLY TARGETING DRUG EFFLUX THROUGH MODULATION OF P-GLYCOPROTEIN ACTIVITY BY SMALL MOLECULES: DESIGN, BIOLOGICAL AND COMPUTATIONAL STUDY. | 2019 | Stefano Guglielmo, Marialessandra Contino, Chiara Riganti, Barbara Rolando, Loretta Lazzarato | |
| Furoxan nitric oxide donors disperse Pseudomonas aeruginosa biofilms, accelerate growth, and repress pyoverdine production | 2017 | Poh, Wee Han; Barraud, Nicolas; Guglielmo, Stefano; Lazzarato, Loretta; Fruttero, Roberta; Rolando, Barbara; Rice, Scott A. | |
| Furoxan-, alkylnitrate-derivatives and related compoundsas anti-trypanosomatid agents: Mechanism of action studies | 2008 | Lucia Boiani; Gabriela Aguirre; Mercedes González; Hugo Cerecetto; Agustina Chidichimo; Juan J. Cazzulo; Massimo Bertinaria; Stefano Guglielmo | |
| gem-Dinitroalkyl Benzenes: A Novel Class of IOP-Lowering Agents for the Treatment of Ocular Hypertension | 2017 | Blangetti, Marco; Rolando, Barbara; Marini, Elisabetta; Chegaev, Konstantin; Guglielmo, Stefano; Lazzarato, Loretta; Laura, Lucarini; Emanuela, Masini; Fruttero, Roberta | |
| Hybrid praziquantel-oxadiazole oxides with activity against Schistosoma mansoni. | 2011 | Daniela Cortese; Francesca Vottero; Stefano Guglielmo; Roberta Fruttero; Alberto Gasco; Latasha Day and David L. Williams. | |
| Leishmanicidal Activity of Novel Synthetic Furoxan and Benzofuroxan Derivatives | 2014 | L. A. Dutra;L. De Almeida;T. G. Passalacqua;J. S. Reis;F. A. E. Torres;I. Martinez;R. G. Peccinini;C. Man Chin;K. Chegaev;S. Guglielmo;R. Fruttero;M. A. S. Graminha;J. L. Dos Santos | |
| Light-Tunable Generation of Singlet Oxygen and Nitric Oxide with a Bichromophoric Molecular Hybrid: a Bimodal Approach to Killing Cancer Cells | 2016 | Fraix, Aurore; Blangetti, Marco; Guglielmo, Stefano; Lazzarato, Loretta; Marino, Nino; Cardile, Venera; Graziano, Adriana C.E.; Manet, Ilse; Fruttero, Roberta; Gasco, Alberto; Sortino, Salvatore | |
| Mitochondrial delivery of phenol substructure triggers mitochondrial depolarization and apoptosis of cancer cells | 2018 | Gazzano, Elena; Lazzarato, Loretta; Rolando, Barbara; Kopecka, Joanna; Guglielmo, Stefano; Costamagna, Costanzo; Chegaev, Konstantin*; Riganti, Chiara | |
| Molecular dynamics simulations reveal the determinants of cyclin-dependent kinase 2 inhibition by 5-nitrosopyrimidine derivatives | 2019 | Guglielmo S.; Cortese D.; Cano C.; Fruttero R. |