CANCELLIERE, CARLOTTA
CANCELLIERE, CARLOTTA
Dip. SCIENZE ONCOLOGICHE - Candiolo (attivo dal 01/01/2002 al 30/04/2013)
Abstract 2743: Accumulation of predicted neoantigens by MMR deficiency triggered by temozolomide treatment of human colorectal cancer
2018-01-01 Barault, Ludovic; Germano, Giovanni; Lamba, Simona; Rospo, Giuseppe; Magri, Alessandro; Maione, Federica; Russo, Mariangela; Crisafulli, Giovanni; Falcomatà, Chiara; Cancelliere, Carlotta; Bartolini, Alice; Lerda, Giulia; Siravegna, Giulia; Mussolin, Benedetta; Frapolli, Roberta; Montone, Monica; Randon, Giovanni; Braud, Filippo de; Amirouchene-Angelozzi, Nabil; Marsoni, Silvia; D'Incalci, Maurizio; Orlandi, Armando; Giraudo, Enrico; Sartore-Bianchi, Andrea; Siena, Salvatore; Pietrantonio, Filippo; Bardelli, Alberto; Nicolantonio, Federica Di
Abstract LB-299: A comprehensive platform of patient-derived xenografts and matched cell lines mirrors the genomic landscape of colorectal cancer
2019-01-01 Lazzari, Luca; Corti, Giorgio; Isella, Claudio; Montone, Monica; Arcella, Pamela; Zanella, Eugenia; Novara, Luca; Barbosa, Fabiane; Cassingena, Andrea; Cancelliere, Carlotta; Medico, Enzo; Sartore-Bianchi, Andrea; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Nicolantonio, Federica Di; Linnebacher, Michael; Bardelli, Alberto; Arena, Sabrina
Abstract LB058: A transcriptome-wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer
2023-01-01 Grasso, Gaia; Marriella, Elisa; Miotto, Martina; Buzo, Kristi; Reilly, Nicole M.; Andrei, Pietro; Vitiello, Pietro P.; Crisafulli, Giovanni; Arena, Sabrina; Rospo, Giuseppe; Corti, Giorgio; Lorenzato, Annalisa; Cancelliere, Carlotta; Barault, Ludovic; Gionfriddo, Giulia; Linnebacher, Michael; Russo, Mariangela; Nicolantonio, Federica Di; Bardelli, Alberto
Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer
2018-01-01 Barault, L; Amatu, A; Siravegna, G; Ponzetti, A; Moran, S; Cassingena, A; Mussolin, B; Falcomatà, C; Binder, Am; Cristiano, C; Oddo, D; Guarrera, S; Cancelliere, C; Bustreo, S; Bencardino, K; Maden, S; Vanzati, A; Zavattari, P; Matullo, G; Truini, M; Grady, Wm; Racca, P; Michels, Kb; Siena, S; Esteller, M; Bardelli, A; Sartore-Bianchi, A; Di Nicolantonio, F.
EGFR blockade reverts resistance to KRAS G12C inhibition in colorectal cancer
2020-01-01 Amodio, Vito; Yaeger, Rona; Arcella, Pamela; Cancelliere, Carlotta; Lamba, Simona; Lorenzato, Annalisa; Arena, Sabrina; Montone, Monica; Mussolin, Benedetta; Bian, Yu; Whaley, Adele; Pinnelli, Marika; Murciano-Goroff, Yonina R; Vakiani, Efsevia; Valeri, Nicola; Liao, Wei-Li; Bhalkikar, Anuja; Thyparambil, Sheeno; Zhao, Hui-Yong; de Stanchina, Elisa; Marsoni, Silvia; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Li, Bob T; Rosen, Neal; Di Nicolantonio, Federica; Bardelli, Alberto; Misale, Sandra
EVALUATION OF DRUG RESPONSES IN NON-TRANSFORMED CELLS CARRYING CANCER ALLELES
2009-01-01 Gallicchio M; Di Nicolantonio F; Arena S.; Zecchin D; Martini M; Flonta S; Stella G; Lamba S; Cancelliere C; Russo M; Geuna M; Appendino G; Fantozzi R; Medico E; Bardelli A.
Loss of the heme exporter FLVCR1a impairs mitochondrial functionality: a new approach against colorectal cancer
2018-01-01 Fiorito Veronica, Destefanis Francesca, Marchi Saverio, Audrito Valentina, Medico Enzo, Cancelliere Carlotta, Bardelli Alberto, Deaglio Silvia, Altruda Fiorella, Pinton Paolo, Tolosano Emanuela
Metabolic adaptation in colorectal cancer: heme export is required for the down-modulation of the tricarboxylic acid cycle
2019-01-01 Veronica Fiorito, F. Destefanis, S. Marchi, E. Gazzano, S. Torretta, V. Audrito, P. Provero, E. Medico, D. Chiabrando, S. Petrillo, P. E. Porporato, C. Cancelliere, A. Bardelli, L. Trusolino, S. Deaglio, F. Altruda, C. Riganti, S. Cardaci, P. Pinton, E. Tolosano.
Metabolic adaptation in colorectal cancer: heme export is required for the down-modulation of the tricarboxylic acid cycle.
2019-01-01 Fiorito V; Destefanis F; Marchi S; Gazzano E; Torretta S; Audrito V; Provero P; Medico E; Chiabrando D; Petrillo S; Porporato P; Cancelliere C; Bardelli A; Trusolino L; Deaglio S; Altruda F; Riganti C; Cardaci S; Pinton P; Tolosano E
Metabolic adaptation in colorectal cancer: heme export is required for the modulation of the tricarboxylic acid cycle.
2019-01-01 Fiorito V; Destefanis F; Marchi S; Gazzano E; Torretta S; Audrito V; Provero P; Medico E; Chiabrando D; Petrillo S; Porporato P; Cancelliere C; Bardelli A; Trusolino L; Deaglio S; Altruda F; Riganti C; Cardaci S; Pinton P; Tolosano E
Molecular landscape of acquired resistance to targeted therapy combinations in BRAF mutant colorectal cancer
2016-01-01 Oddo, D; Sennott, Em; Barault, L; Valtorta, E; Arena, S; Cassingena, A; Filiciotto, G; Marzolla, G; Elez, E; van Geel RM, ; Bartolini, A; Crisafulli, G; Boscaro, V; Godfrey, Jt; Buscarino, M; Cancelliere, C; Linnebacher, M; Corti, G; Truini, M; Siravegna, G; Grasselli, J; Gallicchio, M; Bernards, R; Schellens, Jh; Tabernero, J; Engelman, Ja; Sartore-Bianchi, A; Bardelli, A; Siena, S; Corcoran, Rb; Di Nicolantonio, F.
Patient-derived xenografts and matched cell lines identify pharmacogenomic vulnerabilities in colorectal cancer
2019-01-01 Lazzari L.; Corti G.; Picco G.; Isella C.; Montone M.; Arcella P.; Durinikova E.; Zanella E.R.; Novara L.; Barbosa F.; Cassingena A.; Cancelliere C.; Medico E.; Sartore-Bianchi A.; Siena S.; Garnett M.J.; Bertotti A.; Trusolino L.; Di Nicolantonio F.; Linnebacher M.; Bardelli A.; Arena S.
Temozolomide drives mismatch repair deficiency and fosters neoantigen generation in tumor cells
2019-01-01 Amodio, V; Grmano, G; Barault, L; Lamba, S; Rospo, G; Magri, A; Maione, F; Crisafulli, G; Cancelliere, C; Lerda, G; Bartolini, A; Siravegna, G; Mussolin, B; Frappolli, R; Montone, M; Randon, G; de Braud, F; Angelozzi, NA; Marsoni, S; D'Incalci, M; Orlandi, A; Giraudo, E; Satore-Bianchi, A; Siena, S; Pietrantonio, F; Di Nicolantonio, F; Bardelli, A
The heme biosynthesis-heme export axis is required for the modulation of the tricarboxylic acid cycle
2019-01-01 Veronica Fiorito, F. Destefanis, S. Marchi, E. Gazzano, S. Torretta, V. Audrito, P. Provero, E. Medico, D. Chiabrando, S. Petrillo, P. E. Porporato, C. Cancelliere, A. Bardelli, L. Trusolino, S. Deaglio, F. Altruda, C. Riganti, S. Cardaci, P. Pinton, E. Tolosano.
The heme exporter FLVCR1A modulates cellular redox status and mitochondrial metabolism: implication in colorectal cancer
2017-01-01 Fiorito Veronica, Destefanis Francesca, Marchi Saverio, Medico Enzo, Cancelliere Carlotta, Bardelli Alberto, Silengo Lorenzo, Altruda Fiorella, Pinton Paolo, Tolosano Emanuela
The heme exporter FLVCR1a modulates the tricarboxylic acid cycle: a new target in colorectal cancer
2018-01-01 Fiorito V; Destefanis F; Marchi S; Gazzano E; Audrito V; Medico E; Cancelliere C; Chiabrando D; Petrillo S; Bardelli A; Deaglio S; Altruda F; Riganti C; Pinton P; Tolosano E
The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation
2021-01-01 Fiorito V.; Allocco A.L.; Petrillo S.; Gazzano E.; Torretta S.; Marchi S.; Destefanis F.; Pacelli C.; Audrito V.; Provero P.; Medico E.; Chiabrando D.; Porporato P.E.; Cancelliere C.; Bardelli A.; Trusolino L.; Capitanio N.; Deaglio S.; Altruda F.; Pinton P.; Cardaci S.; Riganti C.; Tolosano E.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets
2015-01-01 Medico, E; Russo, M; Picco, G; Cancelliere, C; Valtorta, E; Corti, G; Buscarino, M; Isella, C; Lamba, S; Martinoglio, B; Veronese, S; Siena, S; Sartore-Bianchi, A; Beccuti, M; Mottolese, M; Linnebacher, M; Cordero, F; Di Nicolantonio, F*; Bardelli, A*; (*co-last and *corresponding authors)
Werner helicase is a synthetic-lethal vulnerability in Mismatch Repair-Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy and Immunotherapy
2021-01-01 Picco, Gabriele; Cattaneo, Chiara Maria; van Vliet, Esmee J; Crisafulli, Giovanni; Rospo, Giuseppe; Consonni, Sarah; Vieira, Sara Filipa; Sanchez Rodriguez, Inigo; Cancelliere, Carlotta; Banerjee, Ruby; Schipper, Luuk Johan; Oddo, Daniele; Dijkstra, Krijn Kristian; Cinatl, Jindrich; Michaelis, Martin; Yang, Fengtang; Uk Group, Cell Model Network; Di Nicolantonio, Federica; Sartore-Bianchi, Andrea; Siena, Salvatore; Arena, Sabrina; Voest, Emile E; Bardelli, Alberto; Garnett, Mathew J
Titolo | Data di pubblicazione | Autore(i) | File |
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Abstract 2743: Accumulation of predicted neoantigens by MMR deficiency triggered by temozolomide treatment of human colorectal cancer | 2018 | Barault, Ludovic; Germano, Giovanni; Lamba, Simona; Rospo, Giuseppe; Magri, Alessandro; Maione, Federica; Russo, Mariangela; Crisafulli, Giovanni; Falcomatà, Chiara; Cancelliere, Carlotta; Bartolini, Alice; Lerda, Giulia; Siravegna, Giulia; Mussolin, Benedetta; Frapolli, Roberta; Montone, Monica; Randon, Giovanni; Braud, Filippo de; Amirouchene-Angelozzi, Nabil; Marsoni, Silvia; D'Incalci, Maurizio; Orlandi, Armando; Giraudo, Enrico; Sartore-Bianchi, Andrea; Siena, Salvatore; Pietrantonio, Filippo; Bardelli, Alberto; Nicolantonio, Federica Di | |
Abstract LB-299: A comprehensive platform of patient-derived xenografts and matched cell lines mirrors the genomic landscape of colorectal cancer | 2019 | Lazzari, Luca; Corti, Giorgio; Isella, Claudio; Montone, Monica; Arcella, Pamela; Zanella, Eugenia; Novara, Luca; Barbosa, Fabiane; Cassingena, Andrea; Cancelliere, Carlotta; Medico, Enzo; Sartore-Bianchi, Andrea; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Nicolantonio, Federica Di; Linnebacher, Michael; Bardelli, Alberto; Arena, Sabrina | |
Abstract LB058: A transcriptome-wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer | 2023 | Grasso, Gaia; Marriella, Elisa; Miotto, Martina; Buzo, Kristi; Reilly, Nicole M.; Andrei, Pietro; Vitiello, Pietro P.; Crisafulli, Giovanni; Arena, Sabrina; Rospo, Giuseppe; Corti, Giorgio; Lorenzato, Annalisa; Cancelliere, Carlotta; Barault, Ludovic; Gionfriddo, Giulia; Linnebacher, Michael; Russo, Mariangela; Nicolantonio, Federica Di; Bardelli, Alberto | |
Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer | 2018 | Barault, L; Amatu, A; Siravegna, G; Ponzetti, A; Moran, S; Cassingena, A; Mussolin, B; Falcomatà, C; Binder, Am; Cristiano, C; Oddo, D; Guarrera, S; Cancelliere, C; Bustreo, S; Bencardino, K; Maden, S; Vanzati, A; Zavattari, P; Matullo, G; Truini, M; Grady, Wm; Racca, P; Michels, Kb; Siena, S; Esteller, M; Bardelli, A; Sartore-Bianchi, A; Di Nicolantonio, F. | |
EGFR blockade reverts resistance to KRAS G12C inhibition in colorectal cancer | 2020 | Amodio, Vito; Yaeger, Rona; Arcella, Pamela; Cancelliere, Carlotta; Lamba, Simona; Lorenzato, Annalisa; Arena, Sabrina; Montone, Monica; Mussolin, Benedetta; Bian, Yu; Whaley, Adele; Pinnelli, Marika; Murciano-Goroff, Yonina R; Vakiani, Efsevia; Valeri, Nicola; Liao, Wei-Li; Bhalkikar, Anuja; Thyparambil, Sheeno; Zhao, Hui-Yong; de Stanchina, Elisa; Marsoni, Silvia; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Li, Bob T; Rosen, Neal; Di Nicolantonio, Federica; Bardelli, Alberto; Misale, Sandra | |
EVALUATION OF DRUG RESPONSES IN NON-TRANSFORMED CELLS CARRYING CANCER ALLELES | 2009 | Gallicchio M; Di Nicolantonio F; Arena S.; Zecchin D; Martini M; Flonta S; Stella G; Lamba S; Cancelliere C; Russo M; Geuna M; Appendino G; Fantozzi R; Medico E; Bardelli A. | |
Loss of the heme exporter FLVCR1a impairs mitochondrial functionality: a new approach against colorectal cancer | 2018 | Fiorito Veronica, Destefanis Francesca, Marchi Saverio, Audrito Valentina, Medico Enzo, Cancelliere Carlotta, Bardelli Alberto, Deaglio Silvia, Altruda Fiorella, Pinton Paolo, Tolosano Emanuela | |
Metabolic adaptation in colorectal cancer: heme export is required for the down-modulation of the tricarboxylic acid cycle | 2019 | Veronica Fiorito, F. Destefanis, S. Marchi, E. Gazzano, S. Torretta, V. Audrito, P. Provero, E. Medico, D. Chiabrando, S. Petrillo, P. E. Porporato, C. Cancelliere, A. Bardelli, L. Trusolino, S. Deaglio, F. Altruda, C. Riganti, S. Cardaci, P. Pinton, E. Tolosano. | |
Metabolic adaptation in colorectal cancer: heme export is required for the down-modulation of the tricarboxylic acid cycle. | 2019 | Fiorito V; Destefanis F; Marchi S; Gazzano E; Torretta S; Audrito V; Provero P; Medico E; Chiabrando D; Petrillo S; Porporato P; Cancelliere C; Bardelli A; Trusolino L; Deaglio S; Altruda F; Riganti C; Cardaci S; Pinton P; Tolosano E | |
Metabolic adaptation in colorectal cancer: heme export is required for the modulation of the tricarboxylic acid cycle. | 2019 | Fiorito V; Destefanis F; Marchi S; Gazzano E; Torretta S; Audrito V; Provero P; Medico E; Chiabrando D; Petrillo S; Porporato P; Cancelliere C; Bardelli A; Trusolino L; Deaglio S; Altruda F; Riganti C; Cardaci S; Pinton P; Tolosano E | |
Molecular landscape of acquired resistance to targeted therapy combinations in BRAF mutant colorectal cancer | 2016 | Oddo, D; Sennott, Em; Barault, L; Valtorta, E; Arena, S; Cassingena, A; Filiciotto, G; Marzolla, G; Elez, E; van Geel RM, ; Bartolini, A; Crisafulli, G; Boscaro, V; Godfrey, Jt; Buscarino, M; Cancelliere, C; Linnebacher, M; Corti, G; Truini, M; Siravegna, G; Grasselli, J; Gallicchio, M; Bernards, R; Schellens, Jh; Tabernero, J; Engelman, Ja; Sartore-Bianchi, A; Bardelli, A; Siena, S; Corcoran, Rb; Di Nicolantonio, F. | |
Patient-derived xenografts and matched cell lines identify pharmacogenomic vulnerabilities in colorectal cancer | 2019 | Lazzari L.; Corti G.; Picco G.; Isella C.; Montone M.; Arcella P.; Durinikova E.; Zanella E.R.; Novara L.; Barbosa F.; Cassingena A.; Cancelliere C.; Medico E.; Sartore-Bianchi A.; Siena S.; Garnett M.J.; Bertotti A.; Trusolino L.; Di Nicolantonio F.; Linnebacher M.; Bardelli A.; Arena S. | |
Temozolomide drives mismatch repair deficiency and fosters neoantigen generation in tumor cells | 2019 | Amodio, V; Grmano, G; Barault, L; Lamba, S; Rospo, G; Magri, A; Maione, F; Crisafulli, G; Cancelliere, C; Lerda, G; Bartolini, A; Siravegna, G; Mussolin, B; Frappolli, R; Montone, M; Randon, G; de Braud, F; Angelozzi, NA; Marsoni, S; D'Incalci, M; Orlandi, A; Giraudo, E; Satore-Bianchi, A; Siena, S; Pietrantonio, F; Di Nicolantonio, F; Bardelli, A | |
The heme biosynthesis-heme export axis is required for the modulation of the tricarboxylic acid cycle | 2019 | Veronica Fiorito, F. Destefanis, S. Marchi, E. Gazzano, S. Torretta, V. Audrito, P. Provero, E. Medico, D. Chiabrando, S. Petrillo, P. E. Porporato, C. Cancelliere, A. Bardelli, L. Trusolino, S. Deaglio, F. Altruda, C. Riganti, S. Cardaci, P. Pinton, E. Tolosano. | |
The heme exporter FLVCR1A modulates cellular redox status and mitochondrial metabolism: implication in colorectal cancer | 2017 | Fiorito Veronica, Destefanis Francesca, Marchi Saverio, Medico Enzo, Cancelliere Carlotta, Bardelli Alberto, Silengo Lorenzo, Altruda Fiorella, Pinton Paolo, Tolosano Emanuela | |
The heme exporter FLVCR1a modulates the tricarboxylic acid cycle: a new target in colorectal cancer | 2018 | Fiorito V; Destefanis F; Marchi S; Gazzano E; Audrito V; Medico E; Cancelliere C; Chiabrando D; Petrillo S; Bardelli A; Deaglio S; Altruda F; Riganti C; Pinton P; Tolosano E | |
The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation | 2021 | Fiorito V.; Allocco A.L.; Petrillo S.; Gazzano E.; Torretta S.; Marchi S.; Destefanis F.; Pacelli C.; Audrito V.; Provero P.; Medico E.; Chiabrando D.; Porporato P.E.; Cancelliere C.; Bardelli A.; Trusolino L.; Capitanio N.; Deaglio S.; Altruda F.; Pinton P.; Cardaci S.; Riganti C.; Tolosano E. | |
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets | 2015 | Medico, E; Russo, M; Picco, G; Cancelliere, C; Valtorta, E; Corti, G; Buscarino, M; Isella, C; Lamba, S; Martinoglio, B; Veronese, S; Siena, S; Sartore-Bianchi, A; Beccuti, M; Mottolese, M; Linnebacher, M; Cordero, F; Di Nicolantonio, F*; Bardelli, A*; (*co-last and *corresponding authors) | |
Werner helicase is a synthetic-lethal vulnerability in Mismatch Repair-Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy and Immunotherapy | 2021 | Picco, Gabriele; Cattaneo, Chiara Maria; van Vliet, Esmee J; Crisafulli, Giovanni; Rospo, Giuseppe; Consonni, Sarah; Vieira, Sara Filipa; Sanchez Rodriguez, Inigo; Cancelliere, Carlotta; Banerjee, Ruby; Schipper, Luuk Johan; Oddo, Daniele; Dijkstra, Krijn Kristian; Cinatl, Jindrich; Michaelis, Martin; Yang, Fengtang; Uk Group, Cell Model Network; Di Nicolantonio, Federica; Sartore-Bianchi, Andrea; Siena, Salvatore; Arena, Sabrina; Voest, Emile E; Bardelli, Alberto; Garnett, Mathew J |