BOSCHI, Donatella
BOSCHI, Donatella
SCIENZA E TECNOLOGIA DEL FARMACO
1H-pyrazole-4-carboxylic acids active against Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH): discovery of a new scaffold for development of antimalarial agents
2014-01-01 Agnese Chiara Pippione; Ulf J. Nilsson; Ingela Fritzson; Anders P. Sundin; Salam Al-Karadaghi; Donatella Boschi; and Marco Lucio Lolli
4-Hydroxy-1H-1,2,3-Triazol-5-yl moiety as bioisoster of carboxylic group. Synthesis and pharmacological ionotropic glutamate receptors characterization of Glu analogues
2014-01-01 S. Sainas; A. Federico;C. Bertolotti; B. Nielsen; D. Boschi; B. Frølund and M. L. Lolli
A differentiating and apoptotic therapy for Acute Myeloid Leukaemia using MEDS433, a potent human Dihydroorotate Dehydrogenase inhibitor
2021-01-01 Stefano Sainas, Paola Circosta, Marta Giorgis, Agnese Chiara Pippione, Marilena Marraudino, Mohammad Houshmand, Brigitta Bonaldo, Valentina Gaidano, Alessandro Cignetti, Stefano Gotti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
A differentiating and apoptotic therapy for acute myeloid leukaemia using potent human dihydroorotate dehydrogenase inhibitors.
2019-01-01 Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Marilena Marraudino, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
A new generation of AKR1C3 inhibitors on the horizon: the 3- hydroxybenzazole approach to target prostate cancer
2023-01-01 Chiara Vigato, Agnese Chiara Pippione, Stefano Sainas, Iole Mannella, Laura Bertarini, Sandra Kovachka, Barbara Rolando, Osman Asghar Mirza, Karla Frydenvang, Francesca Spyrakis, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Donatella Boschi
A new pro-apoptotic therapy for Acute Myeloid Leukaemia using MEDS433, a potent human Dihydroorotate Dehydrogenase inhibitor
2021-01-01 Sainas Sainas, Paola Circosta, Noemi Villella, Elena Martino, Agnese Chiara Pippione, Mohammad Houshmand, Marta Giorgis, Valentina Gaidano, Alessandro Cignetti, Caterina Peraldo Neia, Giovanna Chiorino, Salam Al-Karadaghi, Donatella Boschi, Giuseppe Saglio, Marco Lucio Lolli.
A New Synthetic Approach to Substituted β-Carboline Systems
1999-01-01 GIUSEPPE ERMONDI; SONJA VISENTIN; D. BOSCHI; ROBERTA FRUTTERO; ALBERTO GASCO
Antileishmanial activity of some 4-phenyl-3-amino-1H-pyrazols designed as CRK3 kinase inhibitors
2016-01-01 Agnese Chiara Pippione, Piermichele Kobauri, Stefano Sainas, Alberto Gimenez, Antonella Federico, Rodolpho Campos Braga, Carolina Horta Andrade, Donatella Boschi, Efrain Salamanca, Juan Carlos Ticona, Marco Lucio Lolli
Apoptotic and differentiating therapy for AML using potent human dihydroorotate dehydrogenase inhibitor
2021-01-01 Sainas Sainas, Circosta Paola, Pippione Agnese Chiara, Giorgis Marta, Marraudino Marilena, Houshmand Mohammad, Bonaldo Brigitta, Gaidano Valentina, Cignetti Alessandro, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lolli
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3)
2019-01-01 Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro Bosso, Marco Lucio Lolli, Donatella Boschi
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3)
2019-01-01 Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Donatella Boschi
APPLICATION OF THE ARACHNO™ TECHNOLOGY FOR THE PARALLEL SYNTHESIS OF A LIBRARY OF ASPIRIN ANALOGUES
2015-01-01 Moreo, Angela; Barge, Alessandro; Boschi, Donatella; Costale, Annalisa; Dosio, Franco; Federico, Antonella; Stevanato, Livio; L. Lolli., Marco
Application of the arachno™ technology inside Educational fields: the introduction of parallel synthesis concepts inside an undergraduated lab
2016-01-01 L. Lolli, Marco; *a, ; Angela Moreo, B; Alessandro Barge, A; Donatella Boschi, A; Annalisa Costale, A; Livio Stevanatoa and Franco Dosioa
Aspects of heterocyclic chemistry in developing new 1,4-dihydropyridine Ca2+-antagonists
2000-01-01 SONJA VISENTIN; GIUSEPPE ERMONDI; D. BOSCHI; ROBERTA FRUTTERO; ALBERTO GASCO
Aspects of heterocyclic chemistry in developing new 1,4-dihydropyridines Ca2+-agonists
2000-01-01 S.Visentin; G.Ermondi; D.Boschi; R. Fruttero; A. Gasco
Design and synthesis of a library of pyrazolo[1,5-a]pyridine fluorophores for developing new fluorescent probes
2021-01-01 Elena Martino, Stefano Sainas, Francesco Bavo, Claudio Garino, Donatella Boschi, Bente Frølund, Marco Lucio Lolli
Design of new human Dihydroorotate Dehydrogenase inhibitors: amide bioisosterism in MEDS433 optimization
2021-01-01 Martino Elena, Villella Noemi, Vigato Chiara, Cerrina Matteo, Bersani Matteo, Giorgis Marta, Sainas Stefano, Boschi Donatella, Lolli Marco Lucio
Design, synthesis and co-crystallization of new Plasmodium falciparum dihydroorotate dehydrogenase inhibitors based on hydroxypyrazole scaffold
2019-01-01 Noemi Villella, Agnese Chiara Pippione, Stefano Sainas, Donatella Boschi, Rosmarie Friemann, Alberto Gimenéz, Efrain Salamanca, Marco Lucio Lolli
Design, synthesis and co-crystallization of new Plasmodium falciparum dihydroorotate dehydrogenase inhibitors based on hydroxypyrazole scaffold
2019-01-01 Noemi Villella, Agnese Chiara Pippione, Stefano Sainas, Donatella Boschi, Rosmarie Friemann, Alberto Gimenéz, Efrain Salamanca, Marco Lucio Lolli
Design, synthesis, and biological evaluation of flufenamic acid derived bioisosteres as inhibitors of aldo-keto reductase 1C3 (AKR1C3) expressed in prostate cancer
2016-01-01 Lolli, Marco; Cena, Clara; Giraudo, Alessandro; Marini, Elisabetta; Pippione, Agnese; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Sadiq, Maria; Pors, Klaus; Boschi, Donatella; Braga, Rudolpho; Andrade, Carolina.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1H-pyrazole-4-carboxylic acids active against Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH): discovery of a new scaffold for development of antimalarial agents | 2014 | Agnese Chiara Pippione; Ulf J. Nilsson; Ingela Fritzson; Anders P. Sundin; Salam Al-Karadaghi; Donatella Boschi; and Marco Lucio Lolli | |
| 4-Hydroxy-1H-1,2,3-Triazol-5-yl moiety as bioisoster of carboxylic group. Synthesis and pharmacological ionotropic glutamate receptors characterization of Glu analogues | 2014 | S. Sainas; A. Federico;C. Bertolotti; B. Nielsen; D. Boschi; B. Frølund and M. L. Lolli | |
| A differentiating and apoptotic therapy for Acute Myeloid Leukaemia using MEDS433, a potent human Dihydroorotate Dehydrogenase inhibitor | 2021 | Stefano Sainas, Paola Circosta, Marta Giorgis, Agnese Chiara Pippione, Marilena Marraudino, Mohammad Houshmand, Brigitta Bonaldo, Valentina Gaidano, Alessandro Cignetti, Stefano Gotti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli | |
| A differentiating and apoptotic therapy for acute myeloid leukaemia using potent human dihydroorotate dehydrogenase inhibitors. | 2019 | Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Marilena Marraudino, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli | |
| A new generation of AKR1C3 inhibitors on the horizon: the 3- hydroxybenzazole approach to target prostate cancer | 2023 | Chiara Vigato, Agnese Chiara Pippione, Stefano Sainas, Iole Mannella, Laura Bertarini, Sandra Kovachka, Barbara Rolando, Osman Asghar Mirza, Karla Frydenvang, Francesca Spyrakis, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Donatella Boschi | |
| A new pro-apoptotic therapy for Acute Myeloid Leukaemia using MEDS433, a potent human Dihydroorotate Dehydrogenase inhibitor | 2021 | Sainas Sainas, Paola Circosta, Noemi Villella, Elena Martino, Agnese Chiara Pippione, Mohammad Houshmand, Marta Giorgis, Valentina Gaidano, Alessandro Cignetti, Caterina Peraldo Neia, Giovanna Chiorino, Salam Al-Karadaghi, Donatella Boschi, Giuseppe Saglio, Marco Lucio Lolli. | |
| A New Synthetic Approach to Substituted β-Carboline Systems | 1999 | GIUSEPPE ERMONDI; SONJA VISENTIN; D. BOSCHI; ROBERTA FRUTTERO; ALBERTO GASCO | |
| Antileishmanial activity of some 4-phenyl-3-amino-1H-pyrazols designed as CRK3 kinase inhibitors | 2016 | Agnese Chiara Pippione, Piermichele Kobauri, Stefano Sainas, Alberto Gimenez, Antonella Federico, Rodolpho Campos Braga, Carolina Horta Andrade, Donatella Boschi, Efrain Salamanca, Juan Carlos Ticona, Marco Lucio Lolli | |
| Apoptotic and differentiating therapy for AML using potent human dihydroorotate dehydrogenase inhibitor | 2021 | Sainas Sainas, Circosta Paola, Pippione Agnese Chiara, Giorgis Marta, Marraudino Marilena, Houshmand Mohammad, Bonaldo Brigitta, Gaidano Valentina, Cignetti Alessandro, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lolli | |
| Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) | 2019 | Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro Bosso, Marco Lucio Lolli, Donatella Boschi | |
| Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) | 2019 | Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Donatella Boschi | |
| APPLICATION OF THE ARACHNO™ TECHNOLOGY FOR THE PARALLEL SYNTHESIS OF A LIBRARY OF ASPIRIN ANALOGUES | 2015 | Moreo, Angela; Barge, Alessandro; Boschi, Donatella; Costale, Annalisa; Dosio, Franco; Federico, Antonella; Stevanato, Livio; L. Lolli., Marco | |
| Application of the arachno™ technology inside Educational fields: the introduction of parallel synthesis concepts inside an undergraduated lab | 2016 | L. Lolli, Marco; *a, ; Angela Moreo, B; Alessandro Barge, A; Donatella Boschi, A; Annalisa Costale, A; Livio Stevanatoa and Franco Dosioa | |
| Aspects of heterocyclic chemistry in developing new 1,4-dihydropyridine Ca2+-antagonists | 2000 | SONJA VISENTIN; GIUSEPPE ERMONDI; D. BOSCHI; ROBERTA FRUTTERO; ALBERTO GASCO | |
| Aspects of heterocyclic chemistry in developing new 1,4-dihydropyridines Ca2+-agonists | 2000 | S.Visentin; G.Ermondi; D.Boschi; R. Fruttero; A. Gasco | |
| Design and synthesis of a library of pyrazolo[1,5-a]pyridine fluorophores for developing new fluorescent probes | 2021 | Elena Martino, Stefano Sainas, Francesco Bavo, Claudio Garino, Donatella Boschi, Bente Frølund, Marco Lucio Lolli | |
| Design of new human Dihydroorotate Dehydrogenase inhibitors: amide bioisosterism in MEDS433 optimization | 2021 | Martino Elena, Villella Noemi, Vigato Chiara, Cerrina Matteo, Bersani Matteo, Giorgis Marta, Sainas Stefano, Boschi Donatella, Lolli Marco Lucio | |
| Design, synthesis and co-crystallization of new Plasmodium falciparum dihydroorotate dehydrogenase inhibitors based on hydroxypyrazole scaffold | 2019 | Noemi Villella, Agnese Chiara Pippione, Stefano Sainas, Donatella Boschi, Rosmarie Friemann, Alberto Gimenéz, Efrain Salamanca, Marco Lucio Lolli | |
| Design, synthesis and co-crystallization of new Plasmodium falciparum dihydroorotate dehydrogenase inhibitors based on hydroxypyrazole scaffold | 2019 | Noemi Villella, Agnese Chiara Pippione, Stefano Sainas, Donatella Boschi, Rosmarie Friemann, Alberto Gimenéz, Efrain Salamanca, Marco Lucio Lolli | |
| Design, synthesis, and biological evaluation of flufenamic acid derived bioisosteres as inhibitors of aldo-keto reductase 1C3 (AKR1C3) expressed in prostate cancer | 2016 | Lolli, Marco; Cena, Clara; Giraudo, Alessandro; Marini, Elisabetta; Pippione, Agnese; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Sadiq, Maria; Pors, Klaus; Boschi, Donatella; Braga, Rudolpho; Andrade, Carolina. |