LAMBA, SIMONA ELENA
LAMBA, SIMONA ELENA
ONCOLOGIA
Absence of AKT1 mutations in glioblastoma
2009-01-01 Bleeker FE; Lamba S; Zanon C; van Tilborg AA; Leenstra S; Troost D; Hulsebos T; Vandertop WP; Bardelli A
Abstract 1163: Microenvironment targets in KRAS-mutated metastatic colorectal cancer
2014-01-01 Marchio, Serena; Bartolini, Alice; Cardaci, Sabrina; Soster, Marco; Corti, Giorgio; Lamba, Simona; Bussolino, Federico; Cora', Davide; Di Nicolantonio, Federica
Adaptive mutability of colorectal cancers in response to targeted therapies
2019-01-01 Russo M.; Crisafulli G.; Sogari A.; Reilly N.M.; Arena S.; Lamba S.; Bartolini A.; Amodio V.; Magri A.; Novara L.; Sarotto I.; Nagel Z.D.; Piett C.G.; Amatu A.; Sartore-Bianchi A.; Siena S.; Bertotti A.; Trusolino L.; Corigliano M.; Gherardi M.; Lagomarsino M.C.; Di Nicolantonio F.; Bardelli A.
AKT1 (E17K) in human solid tumours
2008-01-01 Bleeker FE; Felicioni L; Buttitta F; Lamba S; Cardone L; Rodolfo M; Scarpa A; Leenstra S; Frattini M; Barbareschi M; Del Grammastro M; Sciarrotta MG; Zanon C; Marchetti A; Bardelli A
Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab.
2010-01-01 De Roock, W;* Jonker, Dj;* Di Nicolantonio, F; * Sartore-Bianchi, A; Tu, D; Siena, S; Lamba, S; Arena, S; Frattini, M; Piessevaux, H; Van Cutsem, E; O'Callaghan, Cj; Khambata-Ford, S; Zalcberg, Jr; Simes, J; Karapetis, Cs; Bardelli, A; Tejpar, S. (*co-first authorship)
BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS Mutant Colorectal Cancer
2016-01-01 Bartolini, A; Cardaci, S; Lamba, S; Oddo, D; Marchiò, C; Cassoni, P; Amoreo, Ca; Corti, G; Testori, A; Bussolino, F; Pasqualini, R; Arap, W; Corà, D; Di Nicolantonio, F*; Marchiò, S.; *co-last authors and corresponding authors
Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer
2014-01-01 S. Misale;S. Arena;S. Lamba;G. Siravegna;A. Lallo;S. Hobor;M. Russo;M. Buscarino;L. Lazzari;A. Sartore-Bianchi;K. Bencardino;A. Amatu;C. Lauricella;E. Valtorta;S. Siena;F. Di Nicolantonio;A. Bardelli
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients
2015-01-01 Siravegna, Giulia; Mussolin, Benedetta; Buscarino, Michela; Corti, Giorgio; Cassingena, Andrea; Crisafulli, Giovanni; Ponzetti, Agostino; Cremolini, Chiara; Amatu, Alessio; Lauricella, Calogero; Lamba, Simona; Hobor, Sebastijan; Avallone, Antonio; Valtorta, Emanuele; Rospo, Giuseppe; Medico, Enzo; Motta, Valentina; Antoniotti, Carlotta; Tatangelo, Fabiana; Bellosillo, Beatriz; Veronese, Silvio; Budillon, Alfredo; Montagut, Clara; Racca, Patrizia; Marsoni, Silvia; Falcone, Alfredo; Corcoran, Ryan B; Di Nicolantonio, Federica; Loupakis, Fotios; Siena, Salvatore; Sartore-Bianchi, Andrea; Bardelli, Alberto
Dual VEGFA/BRAF targeting boosts PD-1 blockade in melanoma through GM-CSF-mediated infiltration of M1 macrophages
2023-01-01 Comunanza, Valentina; Gigliotti, Chiara; Lamba, Simona; Doronzo, Gabriella; Vallariello, Edoardo; Martin, Valentina; Isella, Claudio; Medico, Enzo; Bardelli, Alberto; Sangiolo, Dario; Di Nicolantonio, Federica; Bussolino, Federico
EGFR blockade reverts resistance to KRAS G12C inhibition in colorectal cancer
2020-01-01 Amodio, Vito; Yaeger, Rona; Arcella, Pamela; Cancelliere, Carlotta; Lamba, Simona; Lorenzato, Annalisa; Arena, Sabrina; Montone, Monica; Mussolin, Benedetta; Bian, Yu; Whaley, Adele; Pinnelli, Marika; Murciano-Goroff, Yonina R; Vakiani, Efsevia; Valeri, Nicola; Liao, Wei-Li; Bhalkikar, Anuja; Thyparambil, Sheeno; Zhao, Hui-Yong; de Stanchina, Elisa; Marsoni, Silvia; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Li, Bob T; Rosen, Neal; Di Nicolantonio, Federica; Bardelli, Alberto; Misale, Sandra
Emergence of MET hyper-amplification at progression to MET and BRAF inhibition in colorectal cancer
2017-01-01 Oddo, D; Siravegna, G; Gloghini, A; Vernieri, C; Mussolin, B; Morano, F; Crisafulli, G; Berenato, R; Corti, G; Volpi, Cc; Buscarino, M; Niger, M; Dunne, Pd; Rospo, G; Valtorta, E; Bartolini, A; Fucà, G; Lamba, S; Martinetti, A; Di Bartolomeo, M; de Braud, F; Bardelli, A; Pietrantonio, F; Di Nicolantonio, F.
EVALUATION OF DRUG RESPONSES IN NON-TRANSFORMED CELLS CARRYING CANCER ALLELES
2009-01-01 Gallicchio M; Di Nicolantonio F; Arena S.; Zecchin D; Martini M; Flonta S; Stella G; Lamba S; Cancelliere C; Russo M; Geuna M; Appendino G; Fantozzi R; Medico E; Bardelli A.
Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance
2023-01-01 Amodio, Vito; Lamba, Simona; Chilà, Rosaria; Cattaneo, Chiara M; Mussolin, Benedetta; Corti, Giorgio; Rospo, Giuseppe; Berrino, Enrico; Tripodo, Claudio; Pisati, Federica; Bartolini, Alice; Aquilano, Maria Costanza; Marsoni, Silvia; Mauri, Gianluca; Marchio', Caterina; Abrignani, Sergio; Di Nicolantonio, Federica; Germano, Giovanni; Bardelli, Alberto
Heat-shock protein 27 (HSP27, HSPB1) is synthetic lethal to cells with oncogenic activation of MET, EGFR and BRAF
2017-01-01 Konda, John D.; Olivero, Martina; Musiani, Daniele; Lamba, Simona; Di Renzo, Maria F.
High-dose Vitamin C enhances cancer immunotherapy
2020-01-01 Magri A.; Germano G.; Lorenzato A.; Lamba S.; Chila R.; Montone M.; Amodio V.; Ceruti T.; Sassi F.; Arena S.; Abrignani S.; D'Incalci M.; Zucchetti M.; Di Nicolantonio F. *; Bardelli A.*; *co-last and corresponding authors
IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors
2009-01-01 Bleeker FE; Lamba S; Leenstra S; Troost D; Hulsebos T; Vandertop WP; Frattini M; Molinari F; Knowles M; Cerrato A; Rodolfo M; Scarpa A; Felicioni L; Buttitta F; Malatesta S; Marchetti A; Bardelli A
Integrated molecular dissection of the epidermal growth factor receptor (EGFR) oncogenic pathway to predict response to EGFR-targeted monoclonal antibodies in metastatic colorectal cancer
2010-01-01 Sartore-Bianchi A; Bencardino K; Di Nicolantonio F; Pozzi F; Funaioli C; Gambi V; Arena S; Martini M; Lamba S; Cassingena A; Schiavo R; Bardelli A; Siena S
Isogenic K-Ras mutant cancer cells: A novel platform for drug profiling
2011-01-01 Goodall J; Hunt J; Chen Z; Di Nicolantonio F; Gallicchio M; Lamba S; Bardelli A; Mahoney C; Astley H; Torrance C; Grimshaw K
KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy.
2013-01-01 Valtorta E; Misale S; Sartore-Bianchi A; Nagtegaal ID; Paraf F; Lauricella C; Dimartino V; Hobor S; Jacobs B; Ercolani C; Lamba S; Scala E; Veronese S ;Laurent-Puig P; Siena S; Tejpar S; Mottolese M; Punt CJ; Gambacorta M; Bardelli A; Di Nicolantonio F
Mixed lineage kinase MLK4 is activated in colorectal cancers where it synergistically cooperates with activated RAS signaling in driving tumorigenesis
2013-01-01 M. Martini; M. Russo; S. Lamba; E. Vitiello; E. H. Crowley; F. Sassi; D. Romanelli; M. Frattini; A. Marchetti; A. Bardelli
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Absence of AKT1 mutations in glioblastoma | 2009 | Bleeker FE; Lamba S; Zanon C; van Tilborg AA; Leenstra S; Troost D; Hulsebos T; Vandertop WP; Bardelli A | |
| Abstract 1163: Microenvironment targets in KRAS-mutated metastatic colorectal cancer | 2014 | Marchio, Serena; Bartolini, Alice; Cardaci, Sabrina; Soster, Marco; Corti, Giorgio; Lamba, Simona; Bussolino, Federico; Cora', Davide; Di Nicolantonio, Federica | |
| Adaptive mutability of colorectal cancers in response to targeted therapies | 2019 | Russo M.; Crisafulli G.; Sogari A.; Reilly N.M.; Arena S.; Lamba S.; Bartolini A.; Amodio V.; Magri A.; Novara L.; Sarotto I.; Nagel Z.D.; Piett C.G.; Amatu A.; Sartore-Bianchi A.; Siena S.; Bertotti A.; Trusolino L.; Corigliano M.; Gherardi M.; Lagomarsino M.C.; Di Nicolantonio F.; Bardelli A. | |
| AKT1 (E17K) in human solid tumours | 2008 | Bleeker FE; Felicioni L; Buttitta F; Lamba S; Cardone L; Rodolfo M; Scarpa A; Leenstra S; Frattini M; Barbareschi M; Del Grammastro M; Sciarrotta MG; Zanon C; Marchetti A; Bardelli A | |
| Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab. | 2010 | De Roock, W;* Jonker, Dj;* Di Nicolantonio, F; * Sartore-Bianchi, A; Tu, D; Siena, S; Lamba, S; Arena, S; Frattini, M; Piessevaux, H; Van Cutsem, E; O'Callaghan, Cj; Khambata-Ford, S; Zalcberg, Jr; Simes, J; Karapetis, Cs; Bardelli, A; Tejpar, S. (*co-first authorship) | |
| BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS Mutant Colorectal Cancer | 2016 | Bartolini, A; Cardaci, S; Lamba, S; Oddo, D; Marchiò, C; Cassoni, P; Amoreo, Ca; Corti, G; Testori, A; Bussolino, F; Pasqualini, R; Arap, W; Corà, D; Di Nicolantonio, F*; Marchiò, S.; *co-last authors and corresponding authors | |
| Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer | 2014 | S. Misale;S. Arena;S. Lamba;G. Siravegna;A. Lallo;S. Hobor;M. Russo;M. Buscarino;L. Lazzari;A. Sartore-Bianchi;K. Bencardino;A. Amatu;C. Lauricella;E. Valtorta;S. Siena;F. Di Nicolantonio;A. Bardelli | |
| Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients | 2015 | Siravegna, Giulia; Mussolin, Benedetta; Buscarino, Michela; Corti, Giorgio; Cassingena, Andrea; Crisafulli, Giovanni; Ponzetti, Agostino; Cremolini, Chiara; Amatu, Alessio; Lauricella, Calogero; Lamba, Simona; Hobor, Sebastijan; Avallone, Antonio; Valtorta, Emanuele; Rospo, Giuseppe; Medico, Enzo; Motta, Valentina; Antoniotti, Carlotta; Tatangelo, Fabiana; Bellosillo, Beatriz; Veronese, Silvio; Budillon, Alfredo; Montagut, Clara; Racca, Patrizia; Marsoni, Silvia; Falcone, Alfredo; Corcoran, Ryan B; Di Nicolantonio, Federica; Loupakis, Fotios; Siena, Salvatore; Sartore-Bianchi, Andrea; Bardelli, Alberto | |
| Dual VEGFA/BRAF targeting boosts PD-1 blockade in melanoma through GM-CSF-mediated infiltration of M1 macrophages | 2023 | Comunanza, Valentina; Gigliotti, Chiara; Lamba, Simona; Doronzo, Gabriella; Vallariello, Edoardo; Martin, Valentina; Isella, Claudio; Medico, Enzo; Bardelli, Alberto; Sangiolo, Dario; Di Nicolantonio, Federica; Bussolino, Federico | |
| EGFR blockade reverts resistance to KRAS G12C inhibition in colorectal cancer | 2020 | Amodio, Vito; Yaeger, Rona; Arcella, Pamela; Cancelliere, Carlotta; Lamba, Simona; Lorenzato, Annalisa; Arena, Sabrina; Montone, Monica; Mussolin, Benedetta; Bian, Yu; Whaley, Adele; Pinnelli, Marika; Murciano-Goroff, Yonina R; Vakiani, Efsevia; Valeri, Nicola; Liao, Wei-Li; Bhalkikar, Anuja; Thyparambil, Sheeno; Zhao, Hui-Yong; de Stanchina, Elisa; Marsoni, Silvia; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Li, Bob T; Rosen, Neal; Di Nicolantonio, Federica; Bardelli, Alberto; Misale, Sandra | |
| Emergence of MET hyper-amplification at progression to MET and BRAF inhibition in colorectal cancer | 2017 | Oddo, D; Siravegna, G; Gloghini, A; Vernieri, C; Mussolin, B; Morano, F; Crisafulli, G; Berenato, R; Corti, G; Volpi, Cc; Buscarino, M; Niger, M; Dunne, Pd; Rospo, G; Valtorta, E; Bartolini, A; Fucà, G; Lamba, S; Martinetti, A; Di Bartolomeo, M; de Braud, F; Bardelli, A; Pietrantonio, F; Di Nicolantonio, F. | |
| EVALUATION OF DRUG RESPONSES IN NON-TRANSFORMED CELLS CARRYING CANCER ALLELES | 2009 | Gallicchio M; Di Nicolantonio F; Arena S.; Zecchin D; Martini M; Flonta S; Stella G; Lamba S; Cancelliere C; Russo M; Geuna M; Appendino G; Fantozzi R; Medico E; Bardelli A. | |
| Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance | 2023 | Amodio, Vito; Lamba, Simona; Chilà, Rosaria; Cattaneo, Chiara M; Mussolin, Benedetta; Corti, Giorgio; Rospo, Giuseppe; Berrino, Enrico; Tripodo, Claudio; Pisati, Federica; Bartolini, Alice; Aquilano, Maria Costanza; Marsoni, Silvia; Mauri, Gianluca; Marchio', Caterina; Abrignani, Sergio; Di Nicolantonio, Federica; Germano, Giovanni; Bardelli, Alberto | |
| Heat-shock protein 27 (HSP27, HSPB1) is synthetic lethal to cells with oncogenic activation of MET, EGFR and BRAF | 2017 | Konda, John D.; Olivero, Martina; Musiani, Daniele; Lamba, Simona; Di Renzo, Maria F. | |
| High-dose Vitamin C enhances cancer immunotherapy | 2020 | Magri A.; Germano G.; Lorenzato A.; Lamba S.; Chila R.; Montone M.; Amodio V.; Ceruti T.; Sassi F.; Arena S.; Abrignani S.; D'Incalci M.; Zucchetti M.; Di Nicolantonio F. *; Bardelli A.*; *co-last and corresponding authors | |
| IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors | 2009 | Bleeker FE; Lamba S; Leenstra S; Troost D; Hulsebos T; Vandertop WP; Frattini M; Molinari F; Knowles M; Cerrato A; Rodolfo M; Scarpa A; Felicioni L; Buttitta F; Malatesta S; Marchetti A; Bardelli A | |
| Integrated molecular dissection of the epidermal growth factor receptor (EGFR) oncogenic pathway to predict response to EGFR-targeted monoclonal antibodies in metastatic colorectal cancer | 2010 | Sartore-Bianchi A; Bencardino K; Di Nicolantonio F; Pozzi F; Funaioli C; Gambi V; Arena S; Martini M; Lamba S; Cassingena A; Schiavo R; Bardelli A; Siena S | |
| Isogenic K-Ras mutant cancer cells: A novel platform for drug profiling | 2011 | Goodall J; Hunt J; Chen Z; Di Nicolantonio F; Gallicchio M; Lamba S; Bardelli A; Mahoney C; Astley H; Torrance C; Grimshaw K | |
| KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy. | 2013 | Valtorta E; Misale S; Sartore-Bianchi A; Nagtegaal ID; Paraf F; Lauricella C; Dimartino V; Hobor S; Jacobs B; Ercolani C; Lamba S; Scala E; Veronese S ;Laurent-Puig P; Siena S; Tejpar S; Mottolese M; Punt CJ; Gambacorta M; Bardelli A; Di Nicolantonio F | |
| Mixed lineage kinase MLK4 is activated in colorectal cancers where it synergistically cooperates with activated RAS signaling in driving tumorigenesis | 2013 | M. Martini; M. Russo; S. Lamba; E. Vitiello; E. H. Crowley; F. Sassi; D. Romanelli; M. Frattini; A. Marchetti; A. Bardelli |