CINECA IRIS Institutional Research Information System

OLIARO BOSSO, Simonetta
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 7.765
EU - Europa 4.126
AS - Asia 4.099
SA - Sud America 440
Continente sconosciuto - Info sul continente non disponibili 397
AF - Africa 153
OC - Oceania 19
Totale 16.999
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 7.511
SG - Singapore 1.457
IT - Italia 1.338
CN - Cina 1.118
SE - Svezia 460
DE - Germania 450
VN - Vietnam 390
IE - Irlanda 348
FR - Francia 335
BR - Brasile 326
FI - Finlandia 247
KR - Corea 210
GB - Regno Unito 188
JP - Giappone 182
IN - India 177
CA - Canada 154
HK - Hong Kong 152
UA - Ucraina 142
AT - Austria 131
PL - Polonia 127
DK - Danimarca 97
ID - Indonesia 85
BD - Bangladesh 62
SN - Senegal 53
AR - Argentina 50
NL - Olanda 50
TW - Taiwan 47
MX - Messico 45
BE - Belgio 34
ES - Italia 32
RU - Federazione Russa 32
TR - Turchia 28
IQ - Iraq 24
PK - Pakistan 24
ZA - Sudafrica 24
TH - Thailandia 22
CH - Svizzera 19
AU - Australia 18
IR - Iran 18
PT - Portogallo 18
MY - Malesia 17
PH - Filippine 17
CO - Colombia 14
JM - Giamaica 14
SA - Arabia Saudita 14
CL - Cile 13
CR - Costa Rica 13
MA - Marocco 13
RO - Romania 13
UZ - Uzbekistan 13
EC - Ecuador 12
EG - Egitto 11
IL - Israele 11
NG - Nigeria 11
VE - Venezuela 11
CZ - Repubblica Ceca 9
LT - Lituania 8
TN - Tunisia 8
KE - Kenya 7
PY - Paraguay 7
SK - Slovacchia (Repubblica Slovacca) 7
BY - Bielorussia 6
DZ - Algeria 6
EU - Europa 6
HR - Croazia 6
NO - Norvegia 6
AE - Emirati Arabi Uniti 5
AL - Albania 5
DO - Repubblica Dominicana 5
ET - Etiopia 5
HN - Honduras 5
NP - Nepal 5
EE - Estonia 4
PR - Porto Rico 4
RS - Serbia 4
SC - Seychelles 4
BO - Bolivia 3
CG - Congo 3
CU - Cuba 3
GT - Guatemala 3
JO - Giordania 3
KG - Kirghizistan 3
KZ - Kazakistan 3
AZ - Azerbaigian 2
GH - Ghana 2
GR - Grecia 2
HU - Ungheria 2
LV - Lettonia 2
LY - Libia 2
MD - Moldavia 2
MO - Macao, regione amministrativa speciale della Cina 2
OM - Oman 2
PE - Perù 2
PS - Palestinian Territory 2
SV - El Salvador 2
TT - Trinidad e Tobago 2
AM - Armenia 1
AO - Angola 1
AW - Aruba 1
BB - Barbados 1
Totale 16.595
Salva come PNG Salva come JPEG
Città #
Singapore 820
San Jose 785
Ashburn 600
Chandler 553
Beijing 502
Santa Clara 425
Dublin 342
Houston 286
Ann Arbor 285
Fairfield 258
Los Angeles 225
Torino 210
Turin 174
Milan 144
Jacksonville 137
Woodbridge 137
Seattle 134
Vienna 121
Wilmington 119
Villeurbanne 113
Nyköping 112
Ho Chi Minh City 106
Dallas 104
Hong Kong 103
Medford 103
Dearborn 99
Warsaw 97
Princeton 96
Lauterbourg 95
Columbus 92
Redwood City 90
Cambridge 89
Helsinki 86
The Dalles 84
Munich 82
Hanoi 79
Buffalo 73
Tokyo 71
New York 70
Rome 67
Pisa 66
Hefei 63
Seoul 60
Boardman 58
Ottawa 55
Council Bluffs 52
Dong Ket 47
Jakarta 47
Fremont 45
Guangzhou 45
Boston 39
Shanghai 38
Düsseldorf 35
Brussels 33
Copenhagen 33
Naples 28
San Diego 28
Brooklyn 27
Frankfurt am Main 27
Hangzhou 27
Orem 27
São Paulo 26
London 24
Toronto 24
Atlanta 22
Phoenix 22
Bengaluru 21
Chicago 21
Mumbai 21
Nanjing 21
Washington 21
Montreal 19
Nuremberg 19
Bologna 18
Turku 18
Norwalk 17
Redondo Beach 17
Taipei 17
Da Nang 16
Haiphong 16
Pittsburgh 16
Verona 16
Kunming 15
Cape Town 14
Denver 14
Philadelphia 14
Amsterdam 13
Changsha 13
Chennai 13
Mexico City 13
Braunschweig 12
Genoa 12
New Delhi 12
San Francisco 12
Bari 11
Krakow 11
Padua 11
Paris 11
Stockholm 11
Ypsilanti 11
Totale 9.683
Salva come PNG Salva come JPEG
Nome #
Androgen-AR axis in primary and metastatic prostate cancer: chasing steroidogenic enzymes for therapeutic intervention 508
Mesoporous silica as topical nanocarriers for quercetin: characterization and in vitro studies 449
Regulation of HMGCoA reductase Activity by Policosanol and Octacosadienol, a New synthetic Analogue of Octacosanol 384
Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae 355
Cannabinoid Delivery Systems for Pain and Inflammation Treatment 319
Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: Application of a bioisosteric scaffold hopping approach to flufenamic acid 286
New aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the hydroxytriazole scaffold 277
Hydroxytriazole derivatives as potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors discovered by bioisosteric scaffold hopping approach 271
Multiple catalytic activities of human 17β-hydroxysteroid dehydrogenase type 7 respond differently to inhibitors. 268
Predictive tests to evaluate oxidative potential of engineered nanomaterials 246
Design, synthesis, and biological evaluation of flufenamic acid derived bioisosteres as inhibitors of aldo-keto reductase 1C3 (AKR1C3) expressed in prostate cancer 245
Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae 239
The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination 238
Extraction and Characterization of Bromelain from Pineapple Core: A Strategy for Pineapple Waste Valorization 237
Thermosensitive nanocomposite hydrogels for intravitreal delivery of cefuroxime 235
NEW HYDROXYAZOLES INHIBITORS OF ALDO-KETO REDUCTASE 1C3 (AKR1C3) OBTAINED BY SCAFFOLD HOPPING FROM FLUFENAMIC ACID AND INDOMETHACIN FOR CASTRATE RESISTANT PROSTATE CANCER 226
Nanomaterials-protein interactions: the case of pristine and functionalized carbon nanotubes and Porcine Gastric Mucin (PGM) 223
Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3 222
Singlet oxygen plays a key role in the toxicity and DNA damage of nanometric TiO2 to human keratinocytes 219
A new bevacizumab carrier for intravitreal administration: Focus on stability 219
Thermoresponsive mesoporous silica nanoparticles as a carrier for skin delivery of quercetin 216
AI-powered discovery and structure-based optimization of new 7-hydroxycoumarine-based AKR1C3 inhibitors able to reverse chemoresistance in aggressive and rare tumors 215
Assessment of in‐situ gelling microemulsion systems upon temperature and dilution condition for corneal delivery of bevacizumab 214
Sistemi nanocompositi termosensibili per la somministrazione intravitreale di cefuroxima 212
Inhibition of the ROS-mediated cytotoxicity and genotoxicity of nano-TiO2 toward human keratinocyte cells by iron doping 205
Synthesis and preliminary pharmacological characterisation of a new class of nitrogen-containing bisphosphonates (N-BPs) 204
Evaluation of Porcine and Aspergillus oryzae α-Amylases as Possible Model for the Human Enzyme 204
4-methyl zymosterone and other 4-methyl intermediates of sterol biosynthesis from yeast mutants engineered in the ERG27 gene encoding 3-ketosteroid reductase 200
New inhibitors of Aldo-Keto Reductase 1C3 (AKR1C3) based on benzoisoxazole scaffold and their potential application in cancer 198
Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast 196
Indoor illumination: A possible pitfall in toxicological assessment of photo-active nanomaterials 192
Exploration of [2 + 2 + 2] cyclotrimerisation methodology to prepare tetrahydroisoquinoline-based compounds with potential aldo-keto reductase 1C3 target affinity 192
New Hydroxybenzoazole Inhibitors of Aldo-Keto Reductase 1C3 (AKR1C3): Disclosure of SAR Investigation to Target Prostate Cancer 190
Aminopropylindenes derived from Grundmann’s ketone as a novel chemotype of oxidosqualene cyclase inhibitors. 189
AKR1C3 is a biomarker and druggable target for oropharyngeal tumors 189
Effect of inhibiting the sterol biosynthesis pathway and the cholesterol content in the regulation of angiogenesis in vitro and in vivo 186
Targeting Castration Resistant Prostate Cancer (CRPC) by innovative AKR1C3 inhibitors based on the 3-hydroxybenzoisoxazole structure 170
Access of the substrate to the active site of yeast oxidosqualene cyclase: a modelling and site-directed mutagenesis approach 163
Multiple-targeting ligands for AKR1C3 enzyme and androgen receptor to target prostate cancer 160
Structure-guided optimization of 3-hydroxybenzoisoxazole derivatives as inhibitors of Aldo-keto reductase 1C3 (AKR1C3) to target prostate cancer 159
Different interaction between oxidosqualene cyclase and steroid-3-ketoreductase from yeasts to mammals 158
4-Methylzymosterone and Other Intermediates of Sterol Biosynthesis from Yeast Mutants Engineered in the ERG27 Gene Encoding 3-Ketosteroid Reductase 157
NEW HYDROXYAZOLES INHIBITORS OF AKR1C3 OBTAINED FROM NSAIDS BY SCAFFOLD HOPPING APPROACH AGAINST CASTRATE RESISTANT PROSTATE CANCER 151
Surface modified TiO2 nanopowders for sunscreen applications 150
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi and pneumocystis carinii 146
Access of the substrate to the active site of squalene and oxidosqualene cyclases: comparative inhibition, site-directed mutagenesis and homology-modelling studies. 145
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis 144
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis. 144
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis appoach. 144
Recent Cannabinoid Delivery Systems 142
Design, Synthesis, and Biological Evaluation of New (2E,6E)-10-(Dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol Ethers as Inhibitors of Human and Trypanosoma cruzi Oxidosqualene Cyclase. 140
Arylpiperidines as a new class of oxidosqualene cyclase inhibitors 139
Characterization of the Channel Constriction Allowingthe Access of the Substrate to the Active Site of YeastOxidosqualene Cyclase 137
protein -protein interaction in sterol biosynthesis: the relationship between sterol-3-keto reductase and oxidosqualene cyclase 135
Yeast Oxidosqualene cyclase (Erg7p) Is a Major Component of Lipid Particles 135
Characterization of C-4 demethylation complex of cholesterol biosynthesis 135
Umbelliferone Aminoalkyl Derivatives asInhibitors of Human Oxidosqualene: Lanosterol Cyclase 135
Inhibitory Effect of Umbelliferone Aminoalkyl Derivatives on Oxidosqualene Cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii, Homo sapiens and Arabidopsis thaliana: a structure-activity study 135
Divergent interactions involving the oxidosqualene cyclase and thesteroid-3-ketoreductase in the sterol biosynthetic pathway ofmammals and yeasts 134
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 133
A mutation in yeast oxidosqualene cyclase (Erg7) makes it independent of 3-ketoreductase activity (Erg27) 133
AI Based Discovery of a New AKR1C3 Inhibitor for Anticancer Applications 129
Mesoporous silica nanoparticles as a promising skin delivery system for methotrexate 129
Oxidosqualene cyclase from Trypanosoma cruzi and Pneumocystis carinii expressed in Yeast: a model for the development of novel antiparasitic agents 127
Yeast Oxidosqualene cyclase (Erg7p) Is a Major Component of Lipid Particles. J. Biol. Chem. (2002) 277, 2406-2412. 126
Effects of new hydroxyazoles inhibitors of AKR1C3 on vitality of prostate and colorectal cancer cell lines 124
POLICOSANOLI DA PULA DI RISO 124
Studio del canale di accesso al sito attivo della ossidosqualene ciclasi di Saccharomyces cerevisiae. 124
Comparative characterization of yeast and human 3-ketosteroid reductase, two moonlighting proteins that share a job 123
A new generation of AKR1C3 inhibitors on the horizon: the 3- hydroxybenzazole approach to target prostate cancer 122
Novel Squalene-Hopene Cyclase Inhibitors derived from Hydroxycoumarins and Hydroxyacetophenones 121
Vinyl sulfide derivatives of oxidosqualene, as inhibitors of oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae. 121
Different Interaction between Oxidosqualene Cyclase and Steroid-3-ketoreductase in Yeast and Mammals 117
Conjugated Methyl Sulfide and phenyl Sulfide Derivatives of Oxidosqualene as Inhibitors of Oxidosqualene and Squalene-Hopene Cyclases. 115
Enzymatic and Chemical In Vitro Reconstitution of Iron-Sulfur Cluster Proteins 114
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) 112
Oxidosqualene cyclase from Saccharomyces cerevisiae: a model for the development of novel antifungal and antiparasitic agents 112
Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents 112
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 112
Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles 112
HYDROXYLATED HETEROCYCLES AS BIOISOSTERES OF THE CARBOXYLIC FUNCTION: DESIGN OF NEW AKR1C3 INHIBITORS ACTIVE IN PROSTATE CANCER 110
polyclonal antibodies against a fragment of oxidosqualene cyclase(erg7p) overexpressed in E.coli recognize the enzyme of different sources 110
Functional characterization by site-directed mutagenesis of human oxidosqualene cyclase (OSC) expressed in Pichia pastoris 110
Subcellular localization of yeast oxidosqualene cyclase and other eukaryotic oxidosqualene cyclases expressed in yeast 109
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, and Pneumocystis carinii 109
Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis, 107
Tailored preparation of modified TiO2 nanopowders for the study of the role of photo-reactivity in the toxicity toward keratinocytes 107
Subcellular localization of oxidosqualene cyclases from Arabidopsis thaliana, Trypanosoma cruzi and Pneumocystis carinii expressed in yeast 107
Interaction of oxidosqualene cyclase with C-4 sterol demethylation complex 106
Difference in the late ergosterol biosynthesis between yeast spheroplasts and intact cells 104
Soybean-germ oil inhibits oxidosqualene cyclase in 3T3 fibroblasts 103
Towards a metabolomic approach to investigate iron-sulfur cluster biogenesis 102
policosanol: updating and perspectives 100
Farnesyloxycoumarins, a New Class of Squalene Hopene Cyclase Inhibitors 98
Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis 90
Unravelling a new enzymatic activity of non-specific lipid transfer protein Cor a 8: A novel lipase from hazelnuts 84
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) 84
New potent selective inhibitors of Trypanosoma cruzi oxidosqualene cyclase. 82
Subcellular distribution and selective inhibition of oxidosqualene cyclases of Trypanosoma cruzi and Pneumocystis carinii expressed in Saccharomyces cerevisiae 82
NEW AKR1C3 INHIBITORS WITH BENZOISOXAZOLE CORE: DESIGN, SYNTHESIS AND BIOLOGICAL ACTIVITY TO TARGET PROSTATE CANCER 74
Totale 16.746
Salva come PNG Salva come JPEG
Categoria #
all - tutte 50.405
article - articoli 0
book - libri 0
conference - conferenze 17.880
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 68.285
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.156 0 58 90 114 58 46 50 52 55 107 294 232
2022/20231.685 179 165 44 159 163 388 145 103 150 31 98 60
2023/20241.080 111 151 71 67 101 132 139 63 7 70 48 120
2024/20252.308 40 133 112 187 541 157 67 146 278 132 200 315
2025/20265.290 514 226 310 453 496 215 899 168 414 646 305 644
2026/2027667 359 308 0 0 0 0 0 0 0 0 0 0
Totale 16.999