CINECA IRIS Institutional Research Information System

OLIARO BOSSO, Simonetta
 Distribuzione geografica
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Continente #
NA - Nord America 4.926
EU - Europa 3.098
AS - Asia 1.975
SA - Sud America 148
AF - Africa 87
OC - Oceania 13
Continente sconosciuto - Info sul continente non disponibili 6
Totale 10.253
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Nazione #
US - Stati Uniti d'America 4.811
IT - Italia 800
CN - Cina 707
SG - Singapore 563
SE - Svezia 449
DE - Germania 353
IE - Irlanda 346
FR - Francia 205
FI - Finlandia 167
KR - Corea 148
GB - Regno Unito 145
UA - Ucraina 138
AT - Austria 127
BR - Brasile 126
JP - Giappone 120
PL - Polonia 111
CA - Canada 93
IN - India 90
VN - Vietnam 86
DK - Danimarca 82
HK - Hong Kong 68
ID - Indonesia 61
SN - Senegal 53
TW - Taiwan 36
BE - Belgio 34
NL - Olanda 30
RU - Federazione Russa 24
TR - Turchia 18
IR - Iran 17
PT - Portogallo 16
CH - Svizzera 15
ES - Italia 15
MX - Messico 15
AU - Australia 13
TH - Thailandia 13
AR - Argentina 12
RO - Romania 12
NG - Nigeria 9
PH - Filippine 8
UZ - Uzbekistan 8
IL - Israele 7
PK - Pakistan 7
SK - Slovacchia (Repubblica Slovacca) 7
EG - Egitto 6
EU - Europa 6
CL - Cile 5
SA - Arabia Saudita 5
ZA - Sudafrica 5
BD - Bangladesh 4
RS - Serbia 4
TN - Tunisia 4
BY - Bielorussia 3
CO - Colombia 3
CU - Cuba 3
CZ - Repubblica Ceca 3
EE - Estonia 3
NO - Norvegia 3
SC - Seychelles 3
AE - Emirati Arabi Uniti 2
GH - Ghana 2
MA - Marocco 2
MY - Malesia 2
AL - Albania 1
BO - Bolivia 1
CI - Costa d'Avorio 1
GR - Grecia 1
GT - Guatemala 1
IQ - Iraq 1
JM - Giamaica 1
JO - Giordania 1
KE - Kenya 1
KG - Kirghizistan 1
LT - Lituania 1
LU - Lussemburgo 1
LV - Lettonia 1
LY - Libia 1
MD - Moldavia 1
MO - Macao, regione amministrativa speciale della Cina 1
PA - Panama 1
PR - Porto Rico 1
SY - Repubblica araba siriana 1
VE - Venezuela 1
Totale 10.253
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Città #
Chandler 553
Santa Clara 342
Dublin 340
Beijing 337
Singapore 297
Ann Arbor 285
Houston 281
Fairfield 258
Torino 210
Ashburn 191
Woodbridge 136
Jacksonville 132
Los Angeles 120
Turin 120
Vienna 120
Wilmington 119
Seattle 117
Villeurbanne 113
Nyköping 112
Medford 101
Dearborn 99
Princeton 95
Redwood City 90
Cambridge 87
Warsaw 86
Columbus 82
Pisa 64
Ottawa 55
Milan 54
Dong Ket 47
Boardman 45
Jakarta 45
Fremont 44
Guangzhou 38
Düsseldorf 35
Brussels 33
Boston 32
New York 32
Hong Kong 31
Shanghai 29
Hefei 26
Helsinki 26
Copenhagen 23
Hangzhou 23
San Diego 23
Tokyo 21
Nanjing 20
Nuremberg 19
Munich 17
Norwalk 17
Mumbai 16
Taipei 16
Toronto 16
Kunming 15
Buffalo 14
London 14
Rome 14
Washington 13
Braunschweig 12
Pittsburgh 12
Ypsilanti 11
Bradford 10
Falls Church 10
Nürnberg 10
Phoenix 10
Taichung 10
Verona 10
Changsha 9
Chengdu 9
Fuzhou 9
Krakow 9
Pune 9
Amsterdam 8
Bucharest 8
Central 8
Jinan 8
Lappeenranta 8
Mountain View 8
San Francisco 8
The Dalles 8
Bagnacavallo 7
Bratislava 7
Naples 7
Paris 7
Philadelphia 7
Piemonte 7
Abuja 6
Belo Horizonte 6
Birmingham 6
Brooklyn 6
Falkenstein 6
Frankfurt am Main 6
Hebei 6
Istanbul 6
Luzhou 6
Menlo Park 6
Musashino 6
Ogaki 6
Parma 6
Porto 6
Totale 6.070
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Nome #
Androgen-AR axis in primary and metastatic prostate cancer: chasing steroidogenic enzymes for therapeutic intervention 387
Mesoporous silica as topical nanocarriers for quercetin: characterization and in vitro studies 343
Regulation of HMGCoA reductase Activity by Policosanol and Octacosadienol, a New synthetic Analogue of Octacosanol 297
Cannabinoid Delivery Systems for Pain and Inflammation Treatment 221
Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae 220
The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination 205
Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: Application of a bioisosteric scaffold hopping approach to flufenamic acid 204
Hydroxytriazole derivatives as potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors discovered by bioisosteric scaffold hopping approach 202
Multiple catalytic activities of human 17β-hydroxysteroid dehydrogenase type 7 respond differently to inhibitors. 200
Predictive tests to evaluate oxidative potential of engineered nanomaterials 198
Nanomaterials-protein interactions: the case of pristine and functionalized carbon nanotubes and Porcine Gastric Mucin (PGM) 190
New aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the hydroxytriazole scaffold 177
Design, synthesis, and biological evaluation of flufenamic acid derived bioisosteres as inhibitors of aldo-keto reductase 1C3 (AKR1C3) expressed in prostate cancer 176
Thermosensitive nanocomposite hydrogels for intravitreal delivery of cefuroxime 167
NEW HYDROXYAZOLES INHIBITORS OF ALDO-KETO REDUCTASE 1C3 (AKR1C3) OBTAINED BY SCAFFOLD HOPPING FROM FLUFENAMIC ACID AND INDOMETHACIN FOR CASTRATE RESISTANT PROSTATE CANCER 160
Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae 158
Inhibition of the ROS-mediated cytotoxicity and genotoxicity of nano-TiO2 toward human keratinocyte cells by iron doping 158
Singlet oxygen plays a key role in the toxicity and DNA damage of nanometric TiO2 to human keratinocytes 157
Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast 146
Thermoresponsive mesoporous silica nanoparticles as a carrier for skin delivery of quercetin 145
Aminopropylindenes derived from Grundmann’s ketone as a novel chemotype of oxidosqualene cyclase inhibitors. 144
Synthesis and preliminary pharmacological characterisation of a new class of nitrogen-containing bisphosphonates (N-BPs) 141
Evaluation of Porcine and Aspergillus oryzae α-Amylases as Possible Model for the Human Enzyme 136
Indoor illumination: A possible pitfall in toxicological assessment of photo-active nanomaterials 133
Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3 131
New inhibitors of Aldo-Keto Reductase 1C3 (AKR1C3) based on benzoisoxazole scaffold and their potential application in cancer 131
Effect of inhibiting the sterol biosynthesis pathway and the cholesterol content in the regulation of angiogenesis in vitro and in vivo 130
Exploration of [2 + 2 + 2] cyclotrimerisation methodology to prepare tetrahydroisoquinoline-based compounds with potential aldo-keto reductase 1C3 target affinity 123
4-methyl zymosterone and other 4-methyl intermediates of sterol biosynthesis from yeast mutants engineered in the ERG27 gene encoding 3-ketosteroid reductase 120
Sistemi nanocompositi termosensibili per la somministrazione intravitreale di cefuroxima 115
Targeting Castration Resistant Prostate Cancer (CRPC) by innovative AKR1C3 inhibitors based on the 3-hydroxybenzoisoxazole structure 112
A new bevacizumab carrier for intravitreal administration: Focus on stability 110
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi and pneumocystis carinii 109
Assessment of in‐situ gelling microemulsion systems upon temperature and dilution condition for corneal delivery of bevacizumab 108
Surface modified TiO2 nanopowders for sunscreen applications 107
New Hydroxybenzoazole Inhibitors of Aldo-Keto Reductase 1C3 (AKR1C3): Disclosure of SAR Investigation to Target Prostate Cancer 104
4-Methylzymosterone and Other Intermediates of Sterol Biosynthesis from Yeast Mutants Engineered in the ERG27 Gene Encoding 3-Ketosteroid Reductase 104
Umbelliferone Aminoalkyl Derivatives asInhibitors of Human Oxidosqualene: Lanosterol Cyclase 104
Recent Cannabinoid Delivery Systems 101
protein -protein interaction in sterol biosynthesis: the relationship between sterol-3-keto reductase and oxidosqualene cyclase 97
NEW HYDROXYAZOLES INHIBITORS OF AKR1C3 OBTAINED FROM NSAIDS BY SCAFFOLD HOPPING APPROACH AGAINST CASTRATE RESISTANT PROSTATE CANCER 96
Different interaction between oxidosqualene cyclase and steroid-3-ketoreductase from yeasts to mammals 96
Studio del canale di accesso al sito attivo della ossidosqualene ciclasi di Saccharomyces cerevisiae. 93
AKR1C3 is a biomarker and druggable target for oropharyngeal tumors 93
Extraction and Characterization of Bromelain from Pineapple Core: A Strategy for Pineapple Waste Valorization 88
POLICOSANOLI DA PULA DI RISO 88
Access of the substrate to the active site of yeast oxidosqualene cyclase: a modelling and site-directed mutagenesis approach 87
Arylpiperidines as a new class of oxidosqualene cyclase inhibitors 87
Comparative characterization of yeast and human 3-ketosteroid reductase, two moonlighting proteins that share a job 86
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis 85
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis appoach. 85
Multiple-targeting ligands for AKR1C3 enzyme and androgen receptor to target prostate cancer 85
Yeast Oxidosqualene cyclase (Erg7p) Is a Major Component of Lipid Particles. J. Biol. Chem. (2002) 277, 2406-2412. 84
Design, Synthesis, and Biological Evaluation of New (2E,6E)-10-(Dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol Ethers as Inhibitors of Human and Trypanosoma cruzi Oxidosqualene Cyclase. 83
Yeast Oxidosqualene cyclase (Erg7p) Is a Major Component of Lipid Particles 83
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis. 83
Vinyl sulfide derivatives of oxidosqualene, as inhibitors of oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae. 83
Characterization of C-4 demethylation complex of cholesterol biosynthesis 83
Divergent interactions involving the oxidosqualene cyclase and thesteroid-3-ketoreductase in the sterol biosynthetic pathway ofmammals and yeasts 82
Tailored preparation of modified TiO2 nanopowders for the study of the role of photo-reactivity in the toxicity toward keratinocytes 82
Mesoporous silica nanoparticles as a promising skin delivery system for methotrexate 82
Oxidosqualene cyclase from Trypanosoma cruzi and Pneumocystis carinii expressed in Yeast: a model for the development of novel antiparasitic agents 81
Inhibitory Effect of Umbelliferone Aminoalkyl Derivatives on Oxidosqualene Cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii, Homo sapiens and Arabidopsis thaliana: a structure-activity study 81
Characterization of the Channel Constriction Allowingthe Access of the Substrate to the Active Site of YeastOxidosqualene Cyclase 80
Oxidosqualene cyclase from Saccharomyces cerevisiae: a model for the development of novel antifungal and antiparasitic agents 79
Subcellular localization of yeast oxidosqualene cyclase and other eukaryotic oxidosqualene cyclases expressed in yeast 79
A mutation in yeast oxidosqualene cyclase (Erg7) makes it independent of 3-ketoreductase activity (Erg27) 78
Access of the substrate to the active site of squalene and oxidosqualene cyclases: comparative inhibition, site-directed mutagenesis and homology-modelling studies. 77
Different Interaction between Oxidosqualene Cyclase and Steroid-3-ketoreductase in Yeast and Mammals 76
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 75
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, and Pneumocystis carinii 75
polyclonal antibodies against a fragment of oxidosqualene cyclase(erg7p) overexpressed in E.coli recognize the enzyme of different sources 74
Novel Squalene-Hopene Cyclase Inhibitors derived from Hydroxycoumarins and Hydroxyacetophenones 68
Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles 68
Conjugated Methyl Sulfide and phenyl Sulfide Derivatives of Oxidosqualene as Inhibitors of Oxidosqualene and Squalene-Hopene Cyclases. 66
Functional characterization by site-directed mutagenesis of human oxidosqualene cyclase (OSC) expressed in Pichia pastoris 66
Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis, 65
Soybean-germ oil inhibits oxidosqualene cyclase in 3T3 fibroblasts 65
Interaction of oxidosqualene cyclase with C-4 sterol demethylation complex 65
Subcellular localization of oxidosqualene cyclases from Arabidopsis thaliana, Trypanosoma cruzi and Pneumocystis carinii expressed in yeast 65
Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents 64
Enzymatic and Chemical In Vitro Reconstitution of Iron-Sulfur Cluster Proteins 64
policosanol: updating and perspectives 63
Difference in the late ergosterol biosynthesis between yeast spheroplasts and intact cells 62
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 61
Towards a metabolomic approach to investigate iron-sulfur cluster biogenesis 59
Subcellular distribution and selective inhibition of oxidosqualene cyclases of Trypanosoma cruzi and Pneumocystis carinii expressed in Saccharomyces cerevisiae 54
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) 50
HYDROXYLATED HETEROCYCLES AS BIOISOSTERES OF THE CARBOXYLIC FUNCTION: DESIGN OF NEW AKR1C3 INHIBITORS ACTIVE IN PROSTATE CANCER 47
Farnesyloxycoumarins, a New Class of Squalene Hopene Cyclase Inhibitors 46
A new generation of AKR1C3 inhibitors on the horizon: the 3- hydroxybenzazole approach to target prostate cancer 44
Structure-guided optimization of 3-hydroxybenzoisoxazole derivatives as inhibitors of Aldo-keto reductase 1C3 (AKR1C3) to target prostate cancer 43
New potent selective inhibitors of Trypanosoma cruzi oxidosqualene cyclase. 43
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) 42
AI Based Discovery of a New AKR1C3 Inhibitor for Anticancer Applications 39
Mutagenesi sito-specifica per lo studio di analogie strutturali tra squalene-opene ciclasi e ossidosqualene ciclasi. 37
Effects of new hydroxyazoles inhibitors of AKR1C3 on vitality of prostate and colorectal cancer cell lines 36
NEW AKR1C3 INHIBITORS WITH BENZOISOXAZOLE CORE: DESIGN, SYNTHESIS AND BIOLOGICAL ACTIVITY TO TARGET PROSTATE CANCER 30
Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis 28
Extraction, purification and in vitro assessment of the antioxidant and anti-inflammatory activity of policosanols from non-psychoactive Cannabis sativa L. 18
Totale 10.598
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Categoria #
all - tutte 34.065
article - articoli 0
book - libri 0
conference - conferenze 12.153
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.218
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020166 0 0 0 0 0 0 0 0 0 0 96 70
2020/20211.136 123 80 70 75 116 92 52 58 152 80 106 132
2021/20221.211 55 58 90 114 58 46 50 52 55 107 294 232
2022/20231.685 179 165 44 159 163 388 145 103 150 31 98 60
2023/20241.080 111 151 71 67 101 132 139 63 7 70 48 120
2024/20251.864 40 133 112 187 541 157 67 146 278 132 71 0
Totale 10.598