CINECA IRIS Institutional Research Information System

OLIARO BOSSO, Simonetta
 Distribuzione geografica
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Continente #
NA - Nord America 4.791
EU - Europa 2.913
AS - Asia 1.631
AF - Africa 81
SA - Sud America 40
OC - Oceania 13
Continente sconosciuto - Info sul continente non disponibili 6
Totale 9.475
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Nazione #
US - Stati Uniti d'America 4.686
IT - Italia 743
CN - Cina 668
SE - Svezia 448
IE - Irlanda 345
SG - Singapore 331
DE - Germania 302
FR - Francia 198
FI - Finlandia 159
KR - Corea 143
GB - Regno Unito 138
UA - Ucraina 137
AT - Austria 115
JP - Giappone 112
PL - Polonia 105
CA - Canada 87
IN - India 86
VN - Vietnam 83
DK - Danimarca 79
ID - Indonesia 59
SN - Senegal 53
HK - Hong Kong 43
BE - Belgio 34
TW - Taiwan 33
BR - Brasile 22
RU - Federazione Russa 22
IR - Iran 16
ES - Italia 15
NL - Olanda 15
AU - Australia 13
CH - Svizzera 13
MX - Messico 13
PT - Portogallo 13
TH - Thailandia 13
RO - Romania 12
AR - Argentina 10
NG - Nigeria 9
TR - Turchia 9
PH - Filippine 7
SK - Slovacchia (Repubblica Slovacca) 7
EG - Egitto 6
EU - Europa 6
UZ - Uzbekistan 6
SA - Arabia Saudita 5
CL - Cile 4
IL - Israele 4
PK - Pakistan 4
RS - Serbia 4
CO - Colombia 3
CU - Cuba 3
CZ - Repubblica Ceca 3
NO - Norvegia 3
SC - Seychelles 3
ZA - Sudafrica 3
AE - Emirati Arabi Uniti 2
GH - Ghana 2
MA - Marocco 2
MY - Malesia 2
BD - Bangladesh 1
BO - Bolivia 1
CI - Costa d'Avorio 1
EE - Estonia 1
GR - Grecia 1
IQ - Iraq 1
JO - Giordania 1
LY - Libia 1
MD - Moldavia 1
MO - Macao, regione amministrativa speciale della Cina 1
PA - Panama 1
PR - Porto Rico 1
SY - Repubblica araba siriana 1
TN - Tunisia 1
Totale 9.475
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Città #
Chandler 553
Dublin 339
Beijing 334
Santa Clara 306
Ann Arbor 285
Houston 281
Singapore 261
Fairfield 258
Torino 210
Ashburn 187
Woodbridge 136
Jacksonville 132
Wilmington 119
Los Angeles 117
Seattle 114
Vienna 114
Villeurbanne 113
Nyköping 112
Medford 101
Dearborn 99
Turin 98
Princeton 95
Redwood City 90
Cambridge 87
Warsaw 84
Columbus 82
Pisa 64
Ottawa 53
Milan 49
Dong Ket 47
Jakarta 45
Boardman 44
Fremont 42
Guangzhou 34
Brussels 33
Boston 31
New York 31
Shanghai 24
Düsseldorf 23
Hangzhou 23
San Diego 23
Helsinki 22
Copenhagen 20
Nanjing 20
Norwalk 17
Tokyo 17
Mumbai 16
Taipei 16
Kunming 15
Hefei 14
Toronto 14
Washington 13
Braunschweig 12
Pittsburgh 12
Rome 12
Buffalo 11
Ypsilanti 11
Bradford 10
Falls Church 10
Hong Kong 10
London 10
Munich 10
Nürnberg 10
Taichung 10
Verona 10
Changsha 9
Chengdu 9
Fuzhou 9
Phoenix 9
Pune 9
Bucharest 8
Central 8
Jinan 8
Mountain View 8
Bagnacavallo 7
Bratislava 7
Naples 7
Paris 7
Philadelphia 7
Piemonte 7
Abuja 6
Birmingham 6
Hebei 6
Krakow 6
Lappeenranta 6
Luzhou 6
Menlo Park 6
Musashino 6
Ogaki 6
Parma 6
Porto 6
Seongbuk-gu 6
Amsterdam 5
Delhi 5
Lachine 5
Leeds 5
Padova 5
Shenyang 5
Toledo 5
Upper Marlboro 5
Totale 5.826
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Nome #
Androgen-AR axis in primary and metastatic prostate cancer: chasing steroidogenic enzymes for therapeutic intervention 362
Mesoporous silica as topical nanocarriers for quercetin: characterization and in vitro studies 329
Regulation of HMGCoA reductase Activity by Policosanol and Octacosadienol, a New synthetic Analogue of Octacosanol 279
Cannabinoid Delivery Systems for Pain and Inflammation Treatment 207
Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae 199
Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: Application of a bioisosteric scaffold hopping approach to flufenamic acid 196
The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination 195
Predictive tests to evaluate oxidative potential of engineered nanomaterials 191
Nanomaterials-protein interactions: the case of pristine and functionalized carbon nanotubes and Porcine Gastric Mucin (PGM) 187
Hydroxytriazole derivatives as potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors discovered by bioisosteric scaffold hopping approach 181
Multiple catalytic activities of human 17β-hydroxysteroid dehydrogenase type 7 respond differently to inhibitors. 181
Design, synthesis, and biological evaluation of flufenamic acid derived bioisosteres as inhibitors of aldo-keto reductase 1C3 (AKR1C3) expressed in prostate cancer 165
Thermosensitive nanocomposite hydrogels for intravitreal delivery of cefuroxime 158
Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae 153
Singlet oxygen plays a key role in the toxicity and DNA damage of nanometric TiO2 to human keratinocytes 153
NEW HYDROXYAZOLES INHIBITORS OF ALDO-KETO REDUCTASE 1C3 (AKR1C3) OBTAINED BY SCAFFOLD HOPPING FROM FLUFENAMIC ACID AND INDOMETHACIN FOR CASTRATE RESISTANT PROSTATE CANCER 152
New aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the hydroxytriazole scaffold 149
Inhibition of the ROS-mediated cytotoxicity and genotoxicity of nano-TiO2 toward human keratinocyte cells by iron doping 148
Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast 144
Aminopropylindenes derived from Grundmann’s ketone as a novel chemotype of oxidosqualene cyclase inhibitors. 138
Thermoresponsive mesoporous silica nanoparticles as a carrier for skin delivery of quercetin 138
Synthesis and preliminary pharmacological characterisation of a new class of nitrogen-containing bisphosphonates (N-BPs) 133
Indoor illumination: A possible pitfall in toxicological assessment of photo-active nanomaterials 128
Effect of inhibiting the sterol biosynthesis pathway and the cholesterol content in the regulation of angiogenesis in vitro and in vivo 125
Evaluation of Porcine and Aspergillus oryzae α-Amylases as Possible Model for the Human Enzyme 124
New inhibitors of Aldo-Keto Reductase 1C3 (AKR1C3) based on benzoisoxazole scaffold and their potential application in cancer 122
Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3 120
Exploration of [2 + 2 + 2] cyclotrimerisation methodology to prepare tetrahydroisoquinoline-based compounds with potential aldo-keto reductase 1C3 target affinity 112
Targeting Castration Resistant Prostate Cancer (CRPC) by innovative AKR1C3 inhibitors based on the 3-hydroxybenzoisoxazole structure 106
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi and pneumocystis carinii 105
4-methyl zymosterone and other 4-methyl intermediates of sterol biosynthesis from yeast mutants engineered in the ERG27 gene encoding 3-ketosteroid reductase 105
Sistemi nanocompositi termosensibili per la somministrazione intravitreale di cefuroxima 103
Surface modified TiO2 nanopowders for sunscreen applications 101
Umbelliferone Aminoalkyl Derivatives asInhibitors of Human Oxidosqualene: Lanosterol Cyclase 99
Recent Cannabinoid Delivery Systems 98
4-Methylzymosterone and Other Intermediates of Sterol Biosynthesis from Yeast Mutants Engineered in the ERG27 Gene Encoding 3-Ketosteroid Reductase 97
New Hydroxybenzoazole Inhibitors of Aldo-Keto Reductase 1C3 (AKR1C3): Disclosure of SAR Investigation to Target Prostate Cancer 94
protein -protein interaction in sterol biosynthesis: the relationship between sterol-3-keto reductase and oxidosqualene cyclase 93
Assessment of in‐situ gelling microemulsion systems upon temperature and dilution condition for corneal delivery of bevacizumab 91
A new bevacizumab carrier for intravitreal administration: Focus on stability 91
NEW HYDROXYAZOLES INHIBITORS OF AKR1C3 OBTAINED FROM NSAIDS BY SCAFFOLD HOPPING APPROACH AGAINST CASTRATE RESISTANT PROSTATE CANCER 89
POLICOSANOLI DA PULA DI RISO 86
Studio del canale di accesso al sito attivo della ossidosqualene ciclasi di Saccharomyces cerevisiae. 84
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis appoach. 83
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis 82
Different interaction between oxidosqualene cyclase and steroid-3-ketoreductase from yeasts to mammals 82
Exploring the access of the substrate to the active site of yeast oxidosqualene cyclase by site-directed mutagenesis. 81
Vinyl sulfide derivatives of oxidosqualene, as inhibitors of oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae. 81
Yeast Oxidosqualene cyclase (Erg7p) Is a Major Component of Lipid Particles. J. Biol. Chem. (2002) 277, 2406-2412. 80
Divergent interactions involving the oxidosqualene cyclase and thesteroid-3-ketoreductase in the sterol biosynthetic pathway ofmammals and yeasts 80
Tailored preparation of modified TiO2 nanopowders for the study of the role of photo-reactivity in the toxicity toward keratinocytes 80
Comparative characterization of yeast and human 3-ketosteroid reductase, two moonlighting proteins that share a job 80
Oxidosqualene cyclase from Trypanosoma cruzi and Pneumocystis carinii expressed in Yeast: a model for the development of novel antiparasitic agents 79
Inhibitory Effect of Umbelliferone Aminoalkyl Derivatives on Oxidosqualene Cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii, Homo sapiens and Arabidopsis thaliana: a structure-activity study 79
Design, Synthesis, and Biological Evaluation of New (2E,6E)-10-(Dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol Ethers as Inhibitors of Human and Trypanosoma cruzi Oxidosqualene Cyclase. 78
Characterization of the Channel Constriction Allowingthe Access of the Substrate to the Active Site of YeastOxidosqualene Cyclase 78
Oxidosqualene cyclase from Saccharomyces cerevisiae: a model for the development of novel antifungal and antiparasitic agents 77
Characterization of C-4 demethylation complex of cholesterol biosynthesis 77
Mesoporous silica nanoparticles as a promising skin delivery system for methotrexate 77
AKR1C3 is a biomarker and druggable target for oropharyngeal tumors 77
Yeast Oxidosqualene cyclase (Erg7p) Is a Major Component of Lipid Particles 76
Access of the substrate to the active site of yeast oxidosqualene cyclase: a modelling and site-directed mutagenesis approach 76
Arylpiperidines as a new class of oxidosqualene cyclase inhibitors 75
Access of the substrate to the active site of squalene and oxidosqualene cyclases: comparative inhibition, site-directed mutagenesis and homology-modelling studies. 74
Subcellular localization of yeast oxidosqualene cyclase and other eukaryotic oxidosqualene cyclases expressed in yeast 73
A mutation in yeast oxidosqualene cyclase (Erg7) makes it independent of 3-ketoreductase activity (Erg27) 73
Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Trypanosoma cruzi, and Pneumocystis carinii 73
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 72
Different Interaction between Oxidosqualene Cyclase and Steroid-3-ketoreductase in Yeast and Mammals 72
polyclonal antibodies against a fragment of oxidosqualene cyclase(erg7p) overexpressed in E.coli recognize the enzyme of different sources 71
Extraction and Characterization of Bromelain from Pineapple Core: A Strategy for Pineapple Waste Valorization 70
Multiple-targeting ligands for AKR1C3 enzyme and androgen receptor to target prostate cancer 70
Novel Squalene-Hopene Cyclase Inhibitors derived from Hydroxycoumarins and Hydroxyacetophenones 65
Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis, 64
Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles 64
Soybean-germ oil inhibits oxidosqualene cyclase in 3T3 fibroblasts 63
Functional characterization by site-directed mutagenesis of human oxidosqualene cyclase (OSC) expressed in Pichia pastoris 63
Subcellular localization of oxidosqualene cyclases from Arabidopsis thaliana, Trypanosoma cruzi and Pneumocystis carinii expressed in yeast 63
Interaction of oxidosqualene cyclase with C-4 sterol demethylation complex 62
Conjugated Methyl Sulfide and phenyl Sulfide Derivatives of Oxidosqualene as Inhibitors of Oxidosqualene and Squalene-Hopene Cyclases. 60
Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents 59
Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach. 58
policosanol: updating and perspectives 58
Difference in the late ergosterol biosynthesis between yeast spheroplasts and intact cells 57
Enzymatic and Chemical In Vitro Reconstitution of Iron-Sulfur Cluster Proteins 53
Towards a metabolomic approach to investigate iron-sulfur cluster biogenesis 52
Subcellular distribution and selective inhibition of oxidosqualene cyclases of Trypanosoma cruzi and Pneumocystis carinii expressed in Saccharomyces cerevisiae 50
Farnesyloxycoumarins, a New Class of Squalene Hopene Cyclase Inhibitors 44
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) 41
New potent selective inhibitors of Trypanosoma cruzi oxidosqualene cyclase. 41
HYDROXYLATED HETEROCYCLES AS BIOISOSTERES OF THE CARBOXYLIC FUNCTION: DESIGN OF NEW AKR1C3 INHIBITORS ACTIVE IN PROSTATE CANCER 36
A new generation of AKR1C3 inhibitors on the horizon: the 3- hydroxybenzazole approach to target prostate cancer 32
Mutagenesi sito-specifica per lo studio di analogie strutturali tra squalene-opene ciclasi e ossidosqualene ciclasi. 32
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) 31
Effects of new hydroxyazoles inhibitors of AKR1C3 on vitality of prostate and colorectal cancer cell lines 29
Structure-guided optimization of 3-hydroxybenzoisoxazole derivatives as inhibitors of Aldo-keto reductase 1C3 (AKR1C3) to target prostate cancer 28
AI Based Discovery of a New AKR1C3 Inhibitor for Anticancer Applications 23
NEW AKR1C3 INHIBITORS WITH BENZOISOXAZOLE CORE: DESIGN, SYNTHESIS AND BIOLOGICAL ACTIVITY TO TARGET PROSTATE CANCER 19
Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis 17
Extraction, purification and in vitro assessment of the antioxidant and anti-inflammatory activity of policosanols from non-psychoactive Cannabis sativa L. 4
Totale 9.805
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Categoria #
all - tutte 29.704
article - articoli 0
book - libri 0
conference - conferenze 10.593
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.297
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020898 0 0 0 0 0 242 151 105 131 103 96 70
2020/20211.136 123 80 70 75 116 92 52 58 152 80 106 132
2021/20221.211 55 58 90 114 58 46 50 52 55 107 294 232
2022/20231.685 179 165 44 159 163 388 145 103 150 31 98 60
2023/20241.080 111 151 71 67 101 132 139 63 7 70 48 120
2024/20251.071 40 133 112 187 541 58 0 0 0 0 0 0
Totale 9.805