FORNASERI, FEDERICO
FORNASERI, FEDERICO
SCIENZA E TECNOLOGIA DEL FARMACO
Discovery of novel and potent human Dihydroorotate Dehydrogenase inhibitor that induces differentiation and apoptosis in Acute Myeloid Leukaemia
2024-01-01 Villella Noemi, Sainas Stefano, Circosta Paola, Caliandro Ileana, Fornaseri Federico, Alberti Marta, Miggiano Riccardo, Giorgis Marta, Vázquez Santiago, Boschi Donatella, Lolli Marco Lucio
Discovery of novel and potent human Dihydroorotate Dehydrogenase inhibitor that induces differentiation and apoptosis in Acute Myeloid Leukaemia
2024-01-01 Villella Noemi, Sainas Stefano, Circosta Paola, Caliandro Ileana, Fornaseri Federico, Alberti Marta, Miggiano Riccardo, Giorgis Marta, Vázquez Santiago, Boschi Donatella, Lolli Marco Lucio
Discovery of novel and potent human Dihydroorotate Dehydrogenase inhibitor that induces differentiation and apoptosis in Acute Myeloid Leukaemia
2024-01-01 Villella Noemi, Sainas Stefano, Circosta Paola, Caliandro Ileana, Fornaseri Federico, Alberti Marta, Miggiano Riccardo, Giorgis Marta, Vázquez Santiago, Boschi Donatella, Lolli Marco Lucio
Identification of a potent and innovative inhibitor of human Dihydroorotate Dehydrogenase, triggering differentiation and apoptosis in Acute Myeloid Leukaemia
2024-01-01 Villella Noemi, Sainas Stefano, Circosta Paola, Caliandro Ileana, Fornaseri Federico, Alberti Marta, Miggiano Riccardo, Giorgis Marta, Vázquez Santiago, Boschi Donatella, Lolli Marco Lucio
Identification of a potent and innovative inhibitor of human Dihydroorotate Dehydrogenase, triggering differentiation and apoptosis in Acute Myeloid Leukaemia
2024-01-01 Villella Noemi, Sainas Stefano, Circosta Paola, Caliandro Ileana, Fornaseri Federico, Alberti Marta, Miggiano Riccardo, Giorgis Marta, Vázquez Santiago, Boschi Donatella, Lolli Marco Lucio
New hydroxypyrazole inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase: physical-chemical characterization and biological evaluation
2024-01-01 Fornaseri Federico, Giorgis Marta, Pippione Agnese Chiara, Caliandro Ileana, Villella Noemi, Alberti Marta, Miggiano Riccardo, Salamanca Efrain, Gimenez Aberto, Sharma Manmohan, Lolli Marco Lucio, Boschi Donatella
Novel benzophenone-, acetophenone-, and benzohydrazide-containing triazolopyrimidines as inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH): Design utilizing combined in silico approaches, synthesis, in vitro enzyme inhibition, and in vivo antimalarial activity
2025-01-01 Sharma, Manmohan; Pippione, Agnese Chiara; Tulsian, Kartik; Fornaseri, Federico; Giorgis, Marta; Boschi, Donatella; Buccinnà, Barbara; Ramondetti, Cristina; Lolli, Marco L.; Vyas, Vivek K.
Off-Target Inhibition of Human Dihydroorotate Dehydrogenase (hDHODH) Highlights Challenges in the Development of Fat Mass and Obesity-Associated Protein (FTO) Inhibitors
2024-01-01 Tarullo M.; Fernandez Rodriguez G.; Iaiza A.; Venezia S.; Macone A.; Incocciati A.; Masciarelli S.; Marchioni M.; Giorgis M.; Lolli M.L.; Fornaseri F.; Proietti L.; Grebien F.; Rosignoli S.; Paiardini A.; Rotili D.; Mai A.; Bochenkova E.; Caflisch A.; Fazi F.; Fatica A.
Structure-based design of new pyrazole inhibitors targeting Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH)
2026-01-01 Pippione, Agnese C.; Villella, Noemi; Fornaseri, Federico; Giorgis, Marta; Sharma, Manmohan; Rolando, Barbara; Sainas, Stefano; Salamanca, Efrain; Gimenez, Alberto; Cojean, Sandrine; Vyas, Vivek K.; Buccinnà, Barbara; Ramondetti, Cristina; Piccinini, Marco; Poli, Giulio; Tuccinardi, Tiziano; Alberti, Marta; Miggiano, Riccardo; Lolli, Marco L.; Boschi, Donatella
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Discovery of novel and potent human Dihydroorotate Dehydrogenase inhibitor that induces differentiation and apoptosis in Acute Myeloid Leukaemia | 2024 | Villella Noemi, Sainas Stefano, Circosta Paola, Caliandro Ileana, Fornaseri Federico, Alberti Marta, Miggiano Riccardo, Giorgis Marta, Vázquez Santiago, Boschi Donatella, Lolli Marco Lucio | |
| Discovery of novel and potent human Dihydroorotate Dehydrogenase inhibitor that induces differentiation and apoptosis in Acute Myeloid Leukaemia | 2024 | Villella Noemi, Sainas Stefano, Circosta Paola, Caliandro Ileana, Fornaseri Federico, Alberti Marta, Miggiano Riccardo, Giorgis Marta, Vázquez Santiago, Boschi Donatella, Lolli Marco Lucio | |
| Discovery of novel and potent human Dihydroorotate Dehydrogenase inhibitor that induces differentiation and apoptosis in Acute Myeloid Leukaemia | 2024 | Villella Noemi, Sainas Stefano, Circosta Paola, Caliandro Ileana, Fornaseri Federico, Alberti Marta, Miggiano Riccardo, Giorgis Marta, Vázquez Santiago, Boschi Donatella, Lolli Marco Lucio | |
| Identification of a potent and innovative inhibitor of human Dihydroorotate Dehydrogenase, triggering differentiation and apoptosis in Acute Myeloid Leukaemia | 2024 | Villella Noemi, Sainas Stefano, Circosta Paola, Caliandro Ileana, Fornaseri Federico, Alberti Marta, Miggiano Riccardo, Giorgis Marta, Vázquez Santiago, Boschi Donatella, Lolli Marco Lucio | |
| Identification of a potent and innovative inhibitor of human Dihydroorotate Dehydrogenase, triggering differentiation and apoptosis in Acute Myeloid Leukaemia | 2024 | Villella Noemi, Sainas Stefano, Circosta Paola, Caliandro Ileana, Fornaseri Federico, Alberti Marta, Miggiano Riccardo, Giorgis Marta, Vázquez Santiago, Boschi Donatella, Lolli Marco Lucio | |
| New hydroxypyrazole inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase: physical-chemical characterization and biological evaluation | 2024 | Fornaseri Federico, Giorgis Marta, Pippione Agnese Chiara, Caliandro Ileana, Villella Noemi, Alberti Marta, Miggiano Riccardo, Salamanca Efrain, Gimenez Aberto, Sharma Manmohan, Lolli Marco Lucio, Boschi Donatella | |
| Novel benzophenone-, acetophenone-, and benzohydrazide-containing triazolopyrimidines as inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH): Design utilizing combined in silico approaches, synthesis, in vitro enzyme inhibition, and in vivo antimalarial activity | 2025 | Sharma, Manmohan; Pippione, Agnese Chiara; Tulsian, Kartik; Fornaseri, Federico; Giorgis, Marta; Boschi, Donatella; Buccinnà, Barbara; Ramondetti, Cristina; Lolli, Marco L.; Vyas, Vivek K. | |
| Off-Target Inhibition of Human Dihydroorotate Dehydrogenase (hDHODH) Highlights Challenges in the Development of Fat Mass and Obesity-Associated Protein (FTO) Inhibitors | 2024 | Tarullo M.; Fernandez Rodriguez G.; Iaiza A.; Venezia S.; Macone A.; Incocciati A.; Masciarelli S.; Marchioni M.; Giorgis M.; Lolli M.L.; Fornaseri F.; Proietti L.; Grebien F.; Rosignoli S.; Paiardini A.; Rotili D.; Mai A.; Bochenkova E.; Caflisch A.; Fazi F.; Fatica A. | |
| Structure-based design of new pyrazole inhibitors targeting Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) | 2026 | Pippione, Agnese C.; Villella, Noemi; Fornaseri, Federico; Giorgis, Marta; Sharma, Manmohan; Rolando, Barbara; Sainas, Stefano; Salamanca, Efrain; Gimenez, Alberto; Cojean, Sandrine; Vyas, Vivek K.; Buccinnà, Barbara; Ramondetti, Cristina; Piccinini, Marco; Poli, Giulio; Tuccinardi, Tiziano; Alberti, Marta; Miggiano, Riccardo; Lolli, Marco L.; Boschi, Donatella |