BERTOTTI, Andrea
BERTOTTI, Andrea
ONCOLOGIA
A diphtheria toxin resistance marker for in vitro and in vivo selection of stably transduced human cells
2015-01-01 Picco, Gabriele; Petti, Consalvo; Trusolino, Livio; Bertotti, Andrea; Medico, Enzo
A modified fluctuation-test framework characterizes the population dynamics and mutation rate of colorectal cancer persister cells
2022-01-01 Russo, Mariangela; Pompei, Simone; Sogari, Alberto; Corigliano, Mattia; Crisafulli, Giovanni; Puliafito, Alberto; Lamba, Simona; Erriquez, Jessica; Bertotti, Andrea; Gherardi, Marco; Di Nicolantonio, Federica; Bardelli, Alberto; Cosentino Lagomarsino, Marco
A module of inflammatory cytokines defines resistance of colorectal cancer to EGFR inhibitors
2016-01-01 Gelfo, Valerio; Rodia, Maria Teresa; Pucci, Michela; Dall'Ora, Massimiliano; Santi, Spartaco; Solmi, Rossella; Roth, Lee; Lindzen, Moshit; Bonafè, Massimiliano; Bertotti, Andrea; Caramelli, Elisabetta; Lollini, Pier-Luigi; Trusolino, Livio; Yarden, Yosef; D'Uva, Gabriele; Lauriola, Mattia
A molecularly annotated model of patient-derived colon cancer stem-like cells to assess genetic and non-genetic mechanisms of resistance to anti-EGFR therapy
2018-01-01 Luraghi, Paolo; Bigatto, Viola; Cipriano, Elia; Reato, Gigliola; Orzan, Francesca; Sassi, Francesco; De Bacco, Francesca; Isella, Claudio; Bellomo, Sara Erika; Medico, Enzo; Comoglio, Paolo M; Bertotti, Andrea; Trusolino, Livio; Boccaccio, Carla
A molecularly annotated platform of patient-derived xenografts (‘xenopatients’) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer
2011-01-01 Bertotti A; Migliardi G; Galimi F; Sassi F; Torti D; Isella C; Corà D; Di Nicolantonio F; Buscarino M; Petti C; Ribero D; Russolillo N; Muratore A; Massucco P; Pisacane A; Molinaro L; Valtorta E; Sartore-Bianchi A; Risio M; Capussotti L; Gambacorta M; Siena S; Medico E; Sapino A; Marsoni S; Comoglio PM; Bardelli A†; Trusolino L† (†Co-Senior authors)
A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors.
2012-01-01 D. Torti;F. Sassi;F. Galimi;S. Gastaldi;T. Perera;P. M. Comoglio;L. Trusolino*; A. Bertotti* (*Co-Senior Authors)
A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth.
2001-01-01 L. TRUSOLINO; A. BERTOTTI; P.M. COMOGLIO
Abstract 2613: A modified Luria-Delbrück assay allows quantification of colorectal cancer persister cells’ mutation rate
2022-01-01 Sogari, Alberto; Russo, Mariangela; Pompei, Simone; Corigliano, Mattia; Crisafulli, Giovanni; Bertotti, Andrea; Gherardi, Marco; Nicolantonio, Federica Di; Lagomarsino, Marco Cosentino; Bardelli, Alberto
Abstract 2848: Radiographic and genomic evolution of individual metastases during HER2 blockade in colorectal cancer
2018-01-01 Siravegna, Giulia; Lazzari, Luca; Sartore-Bianchi, Andrea; Crisafulli, Giovanni; Mussolin, Benedetta; Cassingena, Andrea; Martino, Cosimo; Lanman, Richard; Nagy, Rebecca; Corti, Giorgio; Bartolini, Alice; Arcella, Pamela; Montone, Monica; Lodi, Francesca; Vanzati, Alice; Valtorta, Emanuele; Cappello, Giovanni; Bertotti, Andrea; Lonardi, Sara; Zagonel, Vittorina; Leone, Francesco; Russo, Mariangela; Balsamo, Antonella; Truini, Mauro; Nicolantonio, Federica Di; Amatu, Alessio; Bonazzina, Erica; Ghezzi, Silvia; Regge, Daniele; Vanzulli, Angelo; Trusolino, Livio; Siena, Salvatore; Marsoni, Silvia; Bardelli, Alberto
Abstract 3998: Preclinical efficacy of a synthetic Notch-based combinatorial immunotherapy against colorectal cancer with HER2 amplification
2024-01-01 Cortese, Marco; Torchiaro, Erica; D'Andrea, Alice; Petti, Consalvo; Invrea, Federica; Franco, Letizia; Donini, Chiara; Leuci, Valeria; Leto, Simonetta M.; Vurchio, Valentina; Cottino, Francesca; Isella, Claudio; Arena, Sabrina; Vigna, Elisa; Bertotti, Andrea; Trusolino, Livio; Sangiolo, Dario; Medico, Enzo
Abstract A120: Adaptive mutability of colorectal cancers in response to targeted therapies
2019-01-01 RUSSO, MARIANGELA; Crisafulli, Giovanni; Sogari, Alberto; Reilly, Nicole Megan; Arena, Sabrina; Lamba, Simona; Bartolini, Alice; Amodio, Vito; Magrì, Alessandro; Novara, Luca; Sarotto, Ivana; Nagel, Zachary; Piett, Cortt; Amatu, Alessio; Sartore-Bianchi, Andrea; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Nicolantonio, Federica Di; Bardelli, Alberto
Abstract B33: The oligoclonal antibody MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancer cells harboring EGFR extracellular domain mutations
2016-01-01 Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex; Montagut, Clara; Nicolantonio, Federica Di; Nering, Rachel; Bardelli, Alberto
Abstract LB-299: A comprehensive platform of patient-derived xenografts and matched cell lines mirrors the genomic landscape of colorectal cancer
2019-01-01 Lazzari, Luca; Corti, Giorgio; Isella, Claudio; Montone, Monica; Arcella, Pamela; Zanella, Eugenia; Novara, Luca; Barbosa, Fabiane; Cassingena, Andrea; Cancelliere, Carlotta; Medico, Enzo; Sartore-Bianchi, Andrea; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Nicolantonio, Federica Di; Linnebacher, Michael; Bardelli, Alberto; Arena, Sabrina
Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition.
2010-01-01 S. Corso;E. Ghiso;V. Cepero;J. R. Sierra;C. Migliore;A. Bertotti;L. Trusolino;P. M. Comoglio;S. Giordano
Adaptive mutability of colorectal cancers in response to targeted therapies
2019-01-01 Russo M.; Crisafulli G.; Sogari A.; Reilly N.M.; Arena S.; Lamba S.; Bartolini A.; Amodio V.; Magri A.; Novara L.; Sarotto I.; Nagel Z.D.; Piett C.G.; Amatu A.; Sartore-Bianchi A.; Siena S.; Bertotti A.; Trusolino L.; Corigliano M.; Gherardi M.; Lagomarsino M.C.; Di Nicolantonio F.; Bardelli A.
Amplification of the MET Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer.
2013-01-01 Bardelli A*;Corso S*;Bertotti A*;Hobor S;Valtorta E;Siravegna G;Sartore-Bianchi A;Scala E;Cassingena A;Zecchin D;Apicella M;Migliardi G;Galimi F;Lauricella C;Zanon C;Perera T;Veronese S;Corti G;Amatu A;Gambacorta M;Diaz LA Jr;Sausen M;Velculescu VE;Comoglio P;Trusolino L;Di Nicolantonio F;Giordano S;Siena S (*Co-First Authors)
Animal research: Temper Italy's strict lab-animal law.
2013-01-01 Trusolino L;Bertotti A
Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models.
2014-01-01 Peraldo-Neia C;Cavalloni G;Soster M;Gammaitoni L;Marchiò S;Sassi F;Trusolino L;Bertotti A;Medico E;Capussotti L;Aglietta M;Leone F
Beta4 integrin activates a Shp2-Src signaling pathway that sustains HGF-induced anchorage-independent growth.
2006-01-01 Bertotti A; Comoglio PM; Trusolino L
beta4 integrin is a transforming molecule that unleashes Met tyrosine kinase tumorigenesis.
2005-01-01 Bertotti A; Comoglio PM; Trusolino L
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A diphtheria toxin resistance marker for in vitro and in vivo selection of stably transduced human cells | 2015 | Picco, Gabriele; Petti, Consalvo; Trusolino, Livio; Bertotti, Andrea; Medico, Enzo | |
| A modified fluctuation-test framework characterizes the population dynamics and mutation rate of colorectal cancer persister cells | 2022 | Russo, Mariangela; Pompei, Simone; Sogari, Alberto; Corigliano, Mattia; Crisafulli, Giovanni; Puliafito, Alberto; Lamba, Simona; Erriquez, Jessica; Bertotti, Andrea; Gherardi, Marco; Di Nicolantonio, Federica; Bardelli, Alberto; Cosentino Lagomarsino, Marco | |
| A module of inflammatory cytokines defines resistance of colorectal cancer to EGFR inhibitors | 2016 | Gelfo, Valerio; Rodia, Maria Teresa; Pucci, Michela; Dall'Ora, Massimiliano; Santi, Spartaco; Solmi, Rossella; Roth, Lee; Lindzen, Moshit; Bonafè, Massimiliano; Bertotti, Andrea; Caramelli, Elisabetta; Lollini, Pier-Luigi; Trusolino, Livio; Yarden, Yosef; D'Uva, Gabriele; Lauriola, Mattia | |
| A molecularly annotated model of patient-derived colon cancer stem-like cells to assess genetic and non-genetic mechanisms of resistance to anti-EGFR therapy | 2018 | Luraghi, Paolo; Bigatto, Viola; Cipriano, Elia; Reato, Gigliola; Orzan, Francesca; Sassi, Francesco; De Bacco, Francesca; Isella, Claudio; Bellomo, Sara Erika; Medico, Enzo; Comoglio, Paolo M; Bertotti, Andrea; Trusolino, Livio; Boccaccio, Carla | |
| A molecularly annotated platform of patient-derived xenografts (‘xenopatients’) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer | 2011 | Bertotti A; Migliardi G; Galimi F; Sassi F; Torti D; Isella C; Corà D; Di Nicolantonio F; Buscarino M; Petti C; Ribero D; Russolillo N; Muratore A; Massucco P; Pisacane A; Molinaro L; Valtorta E; Sartore-Bianchi A; Risio M; Capussotti L; Gambacorta M; Siena S; Medico E; Sapino A; Marsoni S; Comoglio PM; Bardelli A†; Trusolino L† (†Co-Senior authors) | |
| A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors. | 2012 | D. Torti;F. Sassi;F. Galimi;S. Gastaldi;T. Perera;P. M. Comoglio;L. Trusolino*; A. Bertotti* (*Co-Senior Authors) | |
| A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth. | 2001 | L. TRUSOLINO; A. BERTOTTI; P.M. COMOGLIO | |
| Abstract 2613: A modified Luria-Delbrück assay allows quantification of colorectal cancer persister cells’ mutation rate | 2022 | Sogari, Alberto; Russo, Mariangela; Pompei, Simone; Corigliano, Mattia; Crisafulli, Giovanni; Bertotti, Andrea; Gherardi, Marco; Nicolantonio, Federica Di; Lagomarsino, Marco Cosentino; Bardelli, Alberto | |
| Abstract 2848: Radiographic and genomic evolution of individual metastases during HER2 blockade in colorectal cancer | 2018 | Siravegna, Giulia; Lazzari, Luca; Sartore-Bianchi, Andrea; Crisafulli, Giovanni; Mussolin, Benedetta; Cassingena, Andrea; Martino, Cosimo; Lanman, Richard; Nagy, Rebecca; Corti, Giorgio; Bartolini, Alice; Arcella, Pamela; Montone, Monica; Lodi, Francesca; Vanzati, Alice; Valtorta, Emanuele; Cappello, Giovanni; Bertotti, Andrea; Lonardi, Sara; Zagonel, Vittorina; Leone, Francesco; Russo, Mariangela; Balsamo, Antonella; Truini, Mauro; Nicolantonio, Federica Di; Amatu, Alessio; Bonazzina, Erica; Ghezzi, Silvia; Regge, Daniele; Vanzulli, Angelo; Trusolino, Livio; Siena, Salvatore; Marsoni, Silvia; Bardelli, Alberto | |
| Abstract 3998: Preclinical efficacy of a synthetic Notch-based combinatorial immunotherapy against colorectal cancer with HER2 amplification | 2024 | Cortese, Marco; Torchiaro, Erica; D'Andrea, Alice; Petti, Consalvo; Invrea, Federica; Franco, Letizia; Donini, Chiara; Leuci, Valeria; Leto, Simonetta M.; Vurchio, Valentina; Cottino, Francesca; Isella, Claudio; Arena, Sabrina; Vigna, Elisa; Bertotti, Andrea; Trusolino, Livio; Sangiolo, Dario; Medico, Enzo | |
| Abstract A120: Adaptive mutability of colorectal cancers in response to targeted therapies | 2019 | RUSSO, MARIANGELA; Crisafulli, Giovanni; Sogari, Alberto; Reilly, Nicole Megan; Arena, Sabrina; Lamba, Simona; Bartolini, Alice; Amodio, Vito; Magrì, Alessandro; Novara, Luca; Sarotto, Ivana; Nagel, Zachary; Piett, Cortt; Amatu, Alessio; Sartore-Bianchi, Andrea; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Nicolantonio, Federica Di; Bardelli, Alberto | |
| Abstract B33: The oligoclonal antibody MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancer cells harboring EGFR extracellular domain mutations | 2016 | Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex; Montagut, Clara; Nicolantonio, Federica Di; Nering, Rachel; Bardelli, Alberto | |
| Abstract LB-299: A comprehensive platform of patient-derived xenografts and matched cell lines mirrors the genomic landscape of colorectal cancer | 2019 | Lazzari, Luca; Corti, Giorgio; Isella, Claudio; Montone, Monica; Arcella, Pamela; Zanella, Eugenia; Novara, Luca; Barbosa, Fabiane; Cassingena, Andrea; Cancelliere, Carlotta; Medico, Enzo; Sartore-Bianchi, Andrea; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Nicolantonio, Federica Di; Linnebacher, Michael; Bardelli, Alberto; Arena, Sabrina | |
| Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition. | 2010 | S. Corso;E. Ghiso;V. Cepero;J. R. Sierra;C. Migliore;A. Bertotti;L. Trusolino;P. M. Comoglio;S. Giordano | |
| Adaptive mutability of colorectal cancers in response to targeted therapies | 2019 | Russo M.; Crisafulli G.; Sogari A.; Reilly N.M.; Arena S.; Lamba S.; Bartolini A.; Amodio V.; Magri A.; Novara L.; Sarotto I.; Nagel Z.D.; Piett C.G.; Amatu A.; Sartore-Bianchi A.; Siena S.; Bertotti A.; Trusolino L.; Corigliano M.; Gherardi M.; Lagomarsino M.C.; Di Nicolantonio F.; Bardelli A. | |
| Amplification of the MET Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer. | 2013 | Bardelli A*;Corso S*;Bertotti A*;Hobor S;Valtorta E;Siravegna G;Sartore-Bianchi A;Scala E;Cassingena A;Zecchin D;Apicella M;Migliardi G;Galimi F;Lauricella C;Zanon C;Perera T;Veronese S;Corti G;Amatu A;Gambacorta M;Diaz LA Jr;Sausen M;Velculescu VE;Comoglio P;Trusolino L;Di Nicolantonio F;Giordano S;Siena S (*Co-First Authors) | |
| Animal research: Temper Italy's strict lab-animal law. | 2013 | Trusolino L;Bertotti A | |
| Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models. | 2014 | Peraldo-Neia C;Cavalloni G;Soster M;Gammaitoni L;Marchiò S;Sassi F;Trusolino L;Bertotti A;Medico E;Capussotti L;Aglietta M;Leone F | |
| Beta4 integrin activates a Shp2-Src signaling pathway that sustains HGF-induced anchorage-independent growth. | 2006 | Bertotti A; Comoglio PM; Trusolino L | |
| beta4 integrin is a transforming molecule that unleashes Met tyrosine kinase tumorigenesis. | 2005 | Bertotti A; Comoglio PM; Trusolino L |