MISALE, SANDRA
MISALE, SANDRA
A stat3-mediated metabolic switch is involved in tumour transformation and stat3 addiction
2011-01-01 Demaria, Marco; Giorgi, Carlotta; Miano, Valentina; Misale, Sandra; Suski, Jan M; Esposito, Giovanna; Provero, Paolo; Wieckowski, Mariusz R; Pinton, Paolo; Poli, Valeria
Abstract 3588: Emergence of multiple EGFR extracellular mutations during cetuximab treatment in colorectal cancer
2015-01-01 Lazzari, Luca; Arena, Sabrina; Bellosillo, Beatriz; Siravegna, Giulia; Martínez, Alejandro; Cañadas, Israel; Ferruz, Noelia; Russo, Mariangela; Misale, Sandra; González, Iria; Iglesias, Mar; Gavilan, Elena; Corti, Giorgio; Hobor, Sebastijan; Crisafulli, Giovanni; Salido, Marta; Sánchez, Juan; Dalmases, Alba; Bellmunt, Joaquim; De Fabritiis, Gianni; Rovira, Ana; Di Nicolantonio, Federica; Albanell, Joan; Bardelli, Alberto; Montagut, Clara
Abstract B110: Heterogeneous genetic alterations emerge during acquired resistance to anti-EGFR therapy in colorectal cancer
2013-01-01 Arena, Sabrina; Misale, Sandra; Lamba, Simona; Siravegna, Giulia; Lallo, Alice; Hobor, Sebastijan; Russo, Mariangela; Buscarino, Michela; Sartore-Bianchi, Andrea; Bencardino, Katia; Amatu, Alessio; Siena, Salvatore; Di Nicolantonio, Federica; Bardelli, Alberto
Abstract B33: The oligoclonal antibody MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancer cells harboring EGFR extracellular domain mutations
2016-01-01 Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex; Montagut, Clara; Nicolantonio, Federica Di; Nering, Rachel; Bardelli, Alberto
Abstract C94: Heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer are sensitive to concomitant inhibition of EGFR and MEK
2013-01-01 Misale, Sandra; Arena, Sabrina; Lamba, Simona; Siravegna, Giulia; Lallo, Alice; Hobor, Sebastijan; Russo, Mariangela; Buscarino, Michela; Sartore-Bianchi, Andrea; Bencardino, Katia; Amatu, Alessio; Siena, Salvatore; Di Nicolantonio, Federica; Bardelli, Alberto
Acquired Resistance to Anti EGFR Therapy in Colorectal Cancer and Paracrine Protection by KRAS Mutated Cells
2012-01-01 Hobor S; Misale S; Crowley E; Scala E; Zanon C; Di Nicolantonio F; Bardelli A
Acquired resistance to the TRK inhibitor entrectinib in colorectal cancer
2016-01-01 Russo, Mariangela; Misale, Sandra; Wei, Ge; Siravegna, Giulia; Crisafulli, Giovanni; Lazzari, Luca; Corti, Giorgio; Rospo, Giuseppe; Novara, Luca; Mussolin, Benedetta; Bartolini, Alice; Cam, Nicholas; Patel, Roopal; Yan, Shunqi; Shoemaker, Robert; Wild, Robert; Di Nicolantonio, Federica; Sartore-Bianchi, Andrea; Li, Gang; Siena, Salvatore; Bardelli, Alberto
Concomitant blockade of EGFR and MEK overcomes acquired resistance to anti-EGFR therapy in colorectal cancer cells and patients’ avatars
2014-01-01 Bardelli, Alberto; Misale, Sandra; Arena, Sabrina; Siravegna, Giulia; Lamba, Simona; Bencardino, Katia; Amatu, Alessio; Valtorta, Emanuele; Lauricella, Calogero; Sartore-Bianchi, Andrea; Di Nicolantonio, Federica; Siena, Salvatore
EGFR blockade reverts resistance to KRAS G12C inhibition in colorectal cancer
2020-01-01 Amodio, Vito; Yaeger, Rona; Arcella, Pamela; Cancelliere, Carlotta; Lamba, Simona; Lorenzato, Annalisa; Arena, Sabrina; Montone, Monica; Mussolin, Benedetta; Bian, Yu; Whaley, Adele; Pinnelli, Marika; Murciano-Goroff, Yonina R; Vakiani, Efsevia; Valeri, Nicola; Liao, Wei-Li; Bhalkikar, Anuja; Thyparambil, Sheeno; Zhao, Hui-Yong; de Stanchina, Elisa; Marsoni, Silvia; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Li, Bob T; Rosen, Neal; Di Nicolantonio, Federica; Bardelli, Alberto; Misale, Sandra
Emergence of KRAS mutations and acquired resistance to anti EGFR therapy in colorectal cancer
2012-01-01 Misale, S; Yaeger, R; Hobor, S; Scala, E; Janakiraman, M; Liska, D; Valtorta, E; Schiavo, R; Buscarino, M; Siravegna, G; Bencardino, K; Cercek, A; Chen, Ct; Veronese, S; Zanon, C; Sartore-Bianchi, A; Gambacorta, M; Gallicchio, M; Vakiani, E; Boscaro, V; Medico, E; Weiser, M; Siena, S; Di Nicolantonio, F; Solit, D; Bardelli, A.
KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy.
2013-01-01 Valtorta E; Misale S; Sartore-Bianchi A; Nagtegaal ID; Paraf F; Lauricella C; Dimartino V; Hobor S; Jacobs B; Ercolani C; Lamba S; Scala E; Veronese S ;Laurent-Puig P; Siena S; Tejpar S; Mottolese M; Punt CJ; Gambacorta M; Bardelli A; Di Nicolantonio F
Metabolic switch between oxidative phosphorylation and glycolysis: a new role for Stat3 in tumours
2010-01-01 Demaria M; Giorgi C; Misale S; Camporeale A; Watson C; Provero P; Pinton P; Poli V
MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations
2016-01-01 Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex A.; Montagut, Clara; Di Nicolantonio, Federica; Nering, Rachel; Bardelli, Alberto
Restoring PUMA induction overcomes KRAS-mediated resistance to anti-EGFR antibodies in colorectal cancer
2018-01-01 Knickelbein, Kyle; Tong, Jingshan; Chen, Dongshi; Wang, Yi-Jun; Misale, Sandra; Bardelli, Alberto; Yu, Jian; Zhang, Lin
STAT3 can serve as a hit in the process of malignant transformation of primary cells
2012-01-01 Demaria M; Misale S; Giorgi C; Miano V; Camporeale A; Campisi J; Pinton P; Poli V.
TGF-α and amphiregulin paracrine network promotes resistance to EGFR blockade in colorectal cancer cells.
2014-01-01 Hobor S;Van Emburgh BO;Crowley E;Misale S;Di Nicolantonio F;Bardelli A
Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers
2015-01-01 Misale, Sandra; Bozic, Ivana; Tong, Jingshan; Peraza-Penton, Ashley; Lallo, Alice; Baldi, Federica; Lin, Kevin H.; Truini, Mauro; Trusolino, Livio; Bertotti, Andrea; Di Nicolantonio, Federica; Nowak, Martin A.; Zhang, Lin; Wood, Kris C.; Bardelli, Alberto
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A stat3-mediated metabolic switch is involved in tumour transformation and stat3 addiction | 2011 | Demaria, Marco; Giorgi, Carlotta; Miano, Valentina; Misale, Sandra; Suski, Jan M; Esposito, Giovanna; Provero, Paolo; Wieckowski, Mariusz R; Pinton, Paolo; Poli, Valeria | |
| Abstract 3588: Emergence of multiple EGFR extracellular mutations during cetuximab treatment in colorectal cancer | 2015 | Lazzari, Luca; Arena, Sabrina; Bellosillo, Beatriz; Siravegna, Giulia; Martínez, Alejandro; Cañadas, Israel; Ferruz, Noelia; Russo, Mariangela; Misale, Sandra; González, Iria; Iglesias, Mar; Gavilan, Elena; Corti, Giorgio; Hobor, Sebastijan; Crisafulli, Giovanni; Salido, Marta; Sánchez, Juan; Dalmases, Alba; Bellmunt, Joaquim; De Fabritiis, Gianni; Rovira, Ana; Di Nicolantonio, Federica; Albanell, Joan; Bardelli, Alberto; Montagut, Clara | |
| Abstract B110: Heterogeneous genetic alterations emerge during acquired resistance to anti-EGFR therapy in colorectal cancer | 2013 | Arena, Sabrina; Misale, Sandra; Lamba, Simona; Siravegna, Giulia; Lallo, Alice; Hobor, Sebastijan; Russo, Mariangela; Buscarino, Michela; Sartore-Bianchi, Andrea; Bencardino, Katia; Amatu, Alessio; Siena, Salvatore; Di Nicolantonio, Federica; Bardelli, Alberto | |
| Abstract B33: The oligoclonal antibody MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancer cells harboring EGFR extracellular domain mutations | 2016 | Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex; Montagut, Clara; Nicolantonio, Federica Di; Nering, Rachel; Bardelli, Alberto | |
| Abstract C94: Heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer are sensitive to concomitant inhibition of EGFR and MEK | 2013 | Misale, Sandra; Arena, Sabrina; Lamba, Simona; Siravegna, Giulia; Lallo, Alice; Hobor, Sebastijan; Russo, Mariangela; Buscarino, Michela; Sartore-Bianchi, Andrea; Bencardino, Katia; Amatu, Alessio; Siena, Salvatore; Di Nicolantonio, Federica; Bardelli, Alberto | |
| Acquired Resistance to Anti EGFR Therapy in Colorectal Cancer and Paracrine Protection by KRAS Mutated Cells | 2012 | Hobor S; Misale S; Crowley E; Scala E; Zanon C; Di Nicolantonio F; Bardelli A | |
| Acquired resistance to the TRK inhibitor entrectinib in colorectal cancer | 2016 | Russo, Mariangela; Misale, Sandra; Wei, Ge; Siravegna, Giulia; Crisafulli, Giovanni; Lazzari, Luca; Corti, Giorgio; Rospo, Giuseppe; Novara, Luca; Mussolin, Benedetta; Bartolini, Alice; Cam, Nicholas; Patel, Roopal; Yan, Shunqi; Shoemaker, Robert; Wild, Robert; Di Nicolantonio, Federica; Sartore-Bianchi, Andrea; Li, Gang; Siena, Salvatore; Bardelli, Alberto | |
| Concomitant blockade of EGFR and MEK overcomes acquired resistance to anti-EGFR therapy in colorectal cancer cells and patients’ avatars | 2014 | Bardelli, Alberto; Misale, Sandra; Arena, Sabrina; Siravegna, Giulia; Lamba, Simona; Bencardino, Katia; Amatu, Alessio; Valtorta, Emanuele; Lauricella, Calogero; Sartore-Bianchi, Andrea; Di Nicolantonio, Federica; Siena, Salvatore | |
| EGFR blockade reverts resistance to KRAS G12C inhibition in colorectal cancer | 2020 | Amodio, Vito; Yaeger, Rona; Arcella, Pamela; Cancelliere, Carlotta; Lamba, Simona; Lorenzato, Annalisa; Arena, Sabrina; Montone, Monica; Mussolin, Benedetta; Bian, Yu; Whaley, Adele; Pinnelli, Marika; Murciano-Goroff, Yonina R; Vakiani, Efsevia; Valeri, Nicola; Liao, Wei-Li; Bhalkikar, Anuja; Thyparambil, Sheeno; Zhao, Hui-Yong; de Stanchina, Elisa; Marsoni, Silvia; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Li, Bob T; Rosen, Neal; Di Nicolantonio, Federica; Bardelli, Alberto; Misale, Sandra | |
| Emergence of KRAS mutations and acquired resistance to anti EGFR therapy in colorectal cancer | 2012 | Misale, S; Yaeger, R; Hobor, S; Scala, E; Janakiraman, M; Liska, D; Valtorta, E; Schiavo, R; Buscarino, M; Siravegna, G; Bencardino, K; Cercek, A; Chen, Ct; Veronese, S; Zanon, C; Sartore-Bianchi, A; Gambacorta, M; Gallicchio, M; Vakiani, E; Boscaro, V; Medico, E; Weiser, M; Siena, S; Di Nicolantonio, F; Solit, D; Bardelli, A. | |
| KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy. | 2013 | Valtorta E; Misale S; Sartore-Bianchi A; Nagtegaal ID; Paraf F; Lauricella C; Dimartino V; Hobor S; Jacobs B; Ercolani C; Lamba S; Scala E; Veronese S ;Laurent-Puig P; Siena S; Tejpar S; Mottolese M; Punt CJ; Gambacorta M; Bardelli A; Di Nicolantonio F | |
| Metabolic switch between oxidative phosphorylation and glycolysis: a new role for Stat3 in tumours | 2010 | Demaria M; Giorgi C; Misale S; Camporeale A; Watson C; Provero P; Pinton P; Poli V | |
| MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations | 2016 | Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex A.; Montagut, Clara; Di Nicolantonio, Federica; Nering, Rachel; Bardelli, Alberto | |
| Restoring PUMA induction overcomes KRAS-mediated resistance to anti-EGFR antibodies in colorectal cancer | 2018 | Knickelbein, Kyle; Tong, Jingshan; Chen, Dongshi; Wang, Yi-Jun; Misale, Sandra; Bardelli, Alberto; Yu, Jian; Zhang, Lin | |
| STAT3 can serve as a hit in the process of malignant transformation of primary cells | 2012 | Demaria M; Misale S; Giorgi C; Miano V; Camporeale A; Campisi J; Pinton P; Poli V. | |
| TGF-α and amphiregulin paracrine network promotes resistance to EGFR blockade in colorectal cancer cells. | 2014 | Hobor S;Van Emburgh BO;Crowley E;Misale S;Di Nicolantonio F;Bardelli A | |
| Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers | 2015 | Misale, Sandra; Bozic, Ivana; Tong, Jingshan; Peraza-Penton, Ashley; Lallo, Alice; Baldi, Federica; Lin, Kevin H.; Truini, Mauro; Trusolino, Livio; Bertotti, Andrea; Di Nicolantonio, Federica; Nowak, Martin A.; Zhang, Lin; Wood, Kris C.; Bardelli, Alberto |