SPYRAKIS, Francesca
SPYRAKIS, Francesca
SCIENZA E TECNOLOGIA DEL FARMACO
A new generation of AKR1C3 inhibitors on the horizon: the 3- hydroxybenzazole approach to target prostate cancer
2023-01-01 Chiara Vigato, Agnese Chiara Pippione, Stefano Sainas, Iole Mannella, Laura Bertarini, Sandra Kovachka, Barbara Rolando, Osman Asghar Mirza, Karla Frydenvang, Francesca Spyrakis, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Donatella Boschi
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3)
2019-01-01 Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro Bosso, Marco Lucio Lolli, Donatella Boschi
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3)
2019-01-01 Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Donatella Boschi
BROAD SPECTRUM METALLO beta-LACTAMASES INHIBITORS: NEW TOOLS AGAINST CLINICALLY-RELEVANT CARBAPENEMASES
2022-01-01 Lazzarato, L.; Failla, M.; Gianquinto, E.; Bersani, M.; Bertarini, L.; Verri, A.; Vascon, F.; Sannio, F.; Verdirosa, F.; Beatrice, N.; De Luca, F.; Costi, M.P.; Cruciani, G.; Docquier, J.D.; Cendron, L.; Spyrakis, F.; Tondi, D.
Essential oils bearing specialized metabolites with potential hypoglycemic activity: a bio-guided fractionation approach driven by in vitro (porcine, human and fungal) α-amylase inhibition assays
2023-01-01 Barbara Sgorbini, Marta Pavarino, Salvatore Adinolfi, Francesca Spyrakis, Cecilia Cagliero, Arianna Marengo, Carlo Bicchi, Patrizia Rubiolo
HYDROXYLATED HETEROCYCLES AS BIOISOSTERES OF THE CARBOXYLIC FUNCTION: DESIGN OF NEW AKR1C3 INHIBITORS ACTIVE IN PROSTATE CANCER
2023-01-01 Agnese C. Pippione, Stefano Sainas, Chiara Vigato, Iole Mannella, Irene Castellino, Sandra Kovachka, Mariia Iakovleva, Barbara Rolando, Tomasz Wrobel, Osman A. Mirza, Karla Frydenvang, Francesca Spyrakis, Simonetta Oliaro-Bosso, Marco L. Lolli, Donatella Boschi
In the search for new NLRP3 inhibitors: chemical modulation of the 1-(piperidin-4-yl)-1,3-dihydro-2 Hbenzo[d]imidazole-2-one scaffold
2021-01-01 Simone Gastaldi, Valentina Boscaro, Eleonora Gianquinto, Christina F. Sandall, Marta Giorgis, Elisabetta Marini, Federica Blua, Margherita Gallicchio, Francesca Spyrakis, Justin A. MacDonald, Massimo Bertinaria
Indomethacin Inhibits Proliferation In Cells Harbouring PIK3CA Mutations
2017-01-01 M. Gallicchio, M. Lolli, F. Spyrakis, D. Bonanni, V. Boscaro
Multiple-targeting ligands for AKR1C3 enzyme and androgen receptor to target prostate cancer
2021-01-01 Agnese Chiara Pippione, Zuhal Kilic-Kurt, Stefano Sainas, Iole Mannella, Barbara Rolando, Sandra Kovachka, Francesca Spyrakis, Annamaria Buschini, Serena Montalbano, Simonetta Oliaro Bosso, Marco Lolli, Donatella Boschi
NEW AKR1C3 INHIBITORS WITH BENZOISOXAZOLE CORE: DESIGN, SYNTHESIS AND BIOLOGICAL ACTIVITY TO TARGET PROSTATE CANCER
2022-01-01 Pippione Agnese Chiara , Iakovleva, M.; Vottero, C.; Sainas, S; Kilic-Kurt, Z.; Rolando, B; Kovachka, S; Spyrakis, F; Buschini, A.; Montalbano, S.; Oliaro Bosso, S.; Lolli, M.L, Boschi, D.
New Hydroxybenzoazole Inhibitors of Aldo-Keto Reductase 1C3 (AKR1C3): Disclosure of SAR Investigation to Target Prostate Cancer
2022-01-01 Chiara Vigato, Agnese Chiara Pippione, Iole Mannella, Mariia Iakovleva, Stefano Sainas, Simonetta Oliaro Bosso, Barbara Rolando, Sandra Kovachka, Francesca Spyrakis, Marco Lucio Lolli, Donatella Boschi
New inhibitors of Aldo-Keto Reductase 1C3 (AKR1C3) based on benzoisoxazole scaffold and their potential application in cancer
2021-01-01 Mannella, Iole, Vigato, Chiara, Pasha, Rabia; Pippione Agnese Chiara, Sainas, Stefano, Oliaro Bosso Simonetta; Rolando, Barbara; Kovachka, Sandra, Spyrakis, Francesca; Boschi, Donatella, Lolli. Marco Lucio
Strigolactone analogs are promising antiviral agents against Herpesviruses
2021-01-01 Matteo Biolatti, Marco Blangetti, Giulia D’Arrigo, Francesca Spyrakis, Paola Cappello, Camilla Albano, Sergio Fernando Castillo Pacheco, Santo Landolfo, Cristina Prandi, Marco De Andrea, Valentina Dell’Oste
Strigolactone Analogs Are Promising Antiviral Agents for the Treatment of Human Cytomegalovirus Infection
2020-01-01 CAMILLA ALBANO, MATTEO BIOLATTI, MARCO BLANGETTI, GIULIA D’ARRIGO, FRANCESCA SPYRAKIS, PAOLA CAPPELLO, PAOLO RAVANINI, SELINA PASQUERO, FRANCESCA GUGLIESI, SERGIO F. CASTILLO PACHECO, SANTO LANDOLFO, MARCO DE ANDREA, CRISTINA PRANDI, VALENTINA DELL’OSTE
Strigolactone analogs are promising antiviral agents for the treatment of human cytomegalovirus infection
2021-01-01 MATTEO BIOLATTI , MARCO BLANGETTI , GIULIA D’ARRIGO, FRANCESCA SPYRAKIS, PAOLA CAPPELLO, CAMILLA ALBANO, SERGIO FERNANDO CASTILLO PACHECO, LINDA TRIFIRO’ , PAOLO RAVANINI , SANTO LANDOLFO, MARCO DE ANDREA, CRISTINA PRANDI , VALENTINA DELL’OSTE
Strigolactones as antiviral drugs to inhibit Herpesvirus replication
2019-01-01 SELINA PASQUERO, GLORIA GRIFFANTE, FRANCESCA GUGLIESI, VALENTINA DELL’OSTE, MATTEO BIOLATTI, GANNA GALITSKA, MARCO BLANGETTI, CRISTINA PRANDI, PAOLA CAPPELLO, FRANCESCA SPYRAKIS, GIULIA D’ARRIGO, MARCO DE ANDREA, SANTO LANDOLFO
Strigolactones as broad-spectrum antivirals against ß-coronaviruses through targeting the main protease Mpro
2023-01-01 G. Bajetto, M. Biolatti, M. Blangetti, M. Baggieri, A. Marchi, S. Gioacchini, D. Arnodo, P. Bucci, R. Fioravanti, M. Kojouri, M. Bersani, G. D’Arrigo, L. Siragusa, S. Ghinato, M. De Andrea, F. Gugliesi, C. Albano, S. Pasquero, I. Visentin, E. D’Ugo, F. Esposito, P. Malune, E. Tramontano, C. Prandi, F. Spyrakis, F. Magurano, Valentina Dell’Oste
Strigolactones as broad-spectrum antivirals against β-coronaviruses through targeting SARS-CoV-2 Mpro
2022-01-01 Camilla Albano, Matteo Biolatti, Marco Blangetti, Greta Bajetto, Davide Arnodo, Melissa Baggeri, Matteo Bersani, Giulia D’Arrigo, Marco De Andrea, Francesca Gugliesi, Selina Pasquero, Ivan Visentin, Cristina Prandi, Francesca Spyrakis, Fabio Magurano, Valentina Dell’Oste
Strigolactones as broad-spectrum antivirals against β-coronaviruses through targeting the main protease Mpro
2023-01-01 Greta Bajetto, Matteo Biolatti, Marco Blangetti, Melissa Baggieri, Davide Arnodo, Raoul Fioravanti, Marco De Andrea, Francesca Gugliesi, Camilla Albano, Selina Pasquero, Ivan Visentin, Francesca Esposito, Paolo Malune, Matteo Bersani, Enzo Tramontano, Cristina Prandi, Francesca Spyrakis, Fabio Magurano
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A new generation of AKR1C3 inhibitors on the horizon: the 3- hydroxybenzazole approach to target prostate cancer | 2023 | Chiara Vigato, Agnese Chiara Pippione, Stefano Sainas, Iole Mannella, Laura Bertarini, Sandra Kovachka, Barbara Rolando, Osman Asghar Mirza, Karla Frydenvang, Francesca Spyrakis, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Donatella Boschi | |
| Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) | 2019 | Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro Bosso, Marco Lucio Lolli, Donatella Boschi | |
| Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) | 2019 | Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Donatella Boschi | |
| BROAD SPECTRUM METALLO beta-LACTAMASES INHIBITORS: NEW TOOLS AGAINST CLINICALLY-RELEVANT CARBAPENEMASES | 2022 | Lazzarato, L.; Failla, M.; Gianquinto, E.; Bersani, M.; Bertarini, L.; Verri, A.; Vascon, F.; Sannio, F.; Verdirosa, F.; Beatrice, N.; De Luca, F.; Costi, M.P.; Cruciani, G.; Docquier, J.D.; Cendron, L.; Spyrakis, F.; Tondi, D. | |
| Essential oils bearing specialized metabolites with potential hypoglycemic activity: a bio-guided fractionation approach driven by in vitro (porcine, human and fungal) α-amylase inhibition assays | 2023 | Barbara Sgorbini, Marta Pavarino, Salvatore Adinolfi, Francesca Spyrakis, Cecilia Cagliero, Arianna Marengo, Carlo Bicchi, Patrizia Rubiolo | |
| HYDROXYLATED HETEROCYCLES AS BIOISOSTERES OF THE CARBOXYLIC FUNCTION: DESIGN OF NEW AKR1C3 INHIBITORS ACTIVE IN PROSTATE CANCER | 2023 | Agnese C. Pippione, Stefano Sainas, Chiara Vigato, Iole Mannella, Irene Castellino, Sandra Kovachka, Mariia Iakovleva, Barbara Rolando, Tomasz Wrobel, Osman A. Mirza, Karla Frydenvang, Francesca Spyrakis, Simonetta Oliaro-Bosso, Marco L. Lolli, Donatella Boschi | |
| In the search for new NLRP3 inhibitors: chemical modulation of the 1-(piperidin-4-yl)-1,3-dihydro-2 Hbenzo[d]imidazole-2-one scaffold | 2021 | Simone Gastaldi, Valentina Boscaro, Eleonora Gianquinto, Christina F. Sandall, Marta Giorgis, Elisabetta Marini, Federica Blua, Margherita Gallicchio, Francesca Spyrakis, Justin A. MacDonald, Massimo Bertinaria | |
| Indomethacin Inhibits Proliferation In Cells Harbouring PIK3CA Mutations | 2017 | M. Gallicchio, M. Lolli, F. Spyrakis, D. Bonanni, V. Boscaro | |
| Multiple-targeting ligands for AKR1C3 enzyme and androgen receptor to target prostate cancer | 2021 | Agnese Chiara Pippione, Zuhal Kilic-Kurt, Stefano Sainas, Iole Mannella, Barbara Rolando, Sandra Kovachka, Francesca Spyrakis, Annamaria Buschini, Serena Montalbano, Simonetta Oliaro Bosso, Marco Lolli, Donatella Boschi | |
| NEW AKR1C3 INHIBITORS WITH BENZOISOXAZOLE CORE: DESIGN, SYNTHESIS AND BIOLOGICAL ACTIVITY TO TARGET PROSTATE CANCER | 2022 | Pippione Agnese Chiara , Iakovleva, M.; Vottero, C.; Sainas, S; Kilic-Kurt, Z.; Rolando, B; Kovachka, S; Spyrakis, F; Buschini, A.; Montalbano, S.; Oliaro Bosso, S.; Lolli, M.L, Boschi, D. | |
| New Hydroxybenzoazole Inhibitors of Aldo-Keto Reductase 1C3 (AKR1C3): Disclosure of SAR Investigation to Target Prostate Cancer | 2022 | Chiara Vigato, Agnese Chiara Pippione, Iole Mannella, Mariia Iakovleva, Stefano Sainas, Simonetta Oliaro Bosso, Barbara Rolando, Sandra Kovachka, Francesca Spyrakis, Marco Lucio Lolli, Donatella Boschi | |
| New inhibitors of Aldo-Keto Reductase 1C3 (AKR1C3) based on benzoisoxazole scaffold and their potential application in cancer | 2021 | Mannella, Iole, Vigato, Chiara, Pasha, Rabia; Pippione Agnese Chiara, Sainas, Stefano, Oliaro Bosso Simonetta; Rolando, Barbara; Kovachka, Sandra, Spyrakis, Francesca; Boschi, Donatella, Lolli. Marco Lucio | |
| Strigolactone analogs are promising antiviral agents against Herpesviruses | 2021 | Matteo Biolatti, Marco Blangetti, Giulia D’Arrigo, Francesca Spyrakis, Paola Cappello, Camilla Albano, Sergio Fernando Castillo Pacheco, Santo Landolfo, Cristina Prandi, Marco De Andrea, Valentina Dell’Oste | |
| Strigolactone Analogs Are Promising Antiviral Agents for the Treatment of Human Cytomegalovirus Infection | 2020 | CAMILLA ALBANO, MATTEO BIOLATTI, MARCO BLANGETTI, GIULIA D’ARRIGO, FRANCESCA SPYRAKIS, PAOLA CAPPELLO, PAOLO RAVANINI, SELINA PASQUERO, FRANCESCA GUGLIESI, SERGIO F. CASTILLO PACHECO, SANTO LANDOLFO, MARCO DE ANDREA, CRISTINA PRANDI, VALENTINA DELL’OSTE | |
| Strigolactone analogs are promising antiviral agents for the treatment of human cytomegalovirus infection | 2021 | MATTEO BIOLATTI , MARCO BLANGETTI , GIULIA D’ARRIGO, FRANCESCA SPYRAKIS, PAOLA CAPPELLO, CAMILLA ALBANO, SERGIO FERNANDO CASTILLO PACHECO, LINDA TRIFIRO’ , PAOLO RAVANINI , SANTO LANDOLFO, MARCO DE ANDREA, CRISTINA PRANDI , VALENTINA DELL’OSTE | |
| Strigolactones as antiviral drugs to inhibit Herpesvirus replication | 2019 | SELINA PASQUERO, GLORIA GRIFFANTE, FRANCESCA GUGLIESI, VALENTINA DELL’OSTE, MATTEO BIOLATTI, GANNA GALITSKA, MARCO BLANGETTI, CRISTINA PRANDI, PAOLA CAPPELLO, FRANCESCA SPYRAKIS, GIULIA D’ARRIGO, MARCO DE ANDREA, SANTO LANDOLFO | |
| Strigolactones as broad-spectrum antivirals against ß-coronaviruses through targeting the main protease Mpro | 2023 | G. Bajetto, M. Biolatti, M. Blangetti, M. Baggieri, A. Marchi, S. Gioacchini, D. Arnodo, P. Bucci, R. Fioravanti, M. Kojouri, M. Bersani, G. D’Arrigo, L. Siragusa, S. Ghinato, M. De Andrea, F. Gugliesi, C. Albano, S. Pasquero, I. Visentin, E. D’Ugo, F. Esposito, P. Malune, E. Tramontano, C. Prandi, F. Spyrakis, F. Magurano, Valentina Dell’Oste | |
| Strigolactones as broad-spectrum antivirals against β-coronaviruses through targeting SARS-CoV-2 Mpro | 2022 | Camilla Albano, Matteo Biolatti, Marco Blangetti, Greta Bajetto, Davide Arnodo, Melissa Baggeri, Matteo Bersani, Giulia D’Arrigo, Marco De Andrea, Francesca Gugliesi, Selina Pasquero, Ivan Visentin, Cristina Prandi, Francesca Spyrakis, Fabio Magurano, Valentina Dell’Oste | |
| Strigolactones as broad-spectrum antivirals against β-coronaviruses through targeting the main protease Mpro | 2023 | Greta Bajetto, Matteo Biolatti, Marco Blangetti, Melissa Baggieri, Davide Arnodo, Raoul Fioravanti, Marco De Andrea, Francesca Gugliesi, Camilla Albano, Selina Pasquero, Ivan Visentin, Francesca Esposito, Paolo Malune, Matteo Bersani, Enzo Tramontano, Cristina Prandi, Francesca Spyrakis, Fabio Magurano |