Serum ACE value was determined in 38 silicotic patients with varying degrees of X-ray profusion. The subjects were elderly and had a rather long history both of exposure and withdrawal. Mean enzyme values did not differ significantly from those of a normal control group. Silicotic patients with advanced radiologic profusion showed higher sACE values than silicotics with mild profusion, though without statistical significance. No correlation was found between sACE values and years of exposure, latency from the beginning and latency from the end of silica dust exposure. High sACE values could be related to active stages of silicosis so that longitudinal determinations in different phases of dust disease appear to be useful in clarifying the trend of the enzyme level in the disease.
Serum angiotensin-converting enzyme level in silicosis
ROMANO, Canzio;
1985-01-01
Abstract
Serum ACE value was determined in 38 silicotic patients with varying degrees of X-ray profusion. The subjects were elderly and had a rather long history both of exposure and withdrawal. Mean enzyme values did not differ significantly from those of a normal control group. Silicotic patients with advanced radiologic profusion showed higher sACE values than silicotics with mild profusion, though without statistical significance. No correlation was found between sACE values and years of exposure, latency from the beginning and latency from the end of silica dust exposure. High sACE values could be related to active stages of silicosis so that longitudinal determinations in different phases of dust disease appear to be useful in clarifying the trend of the enzyme level in the disease.
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