The endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, i.e. central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the biology of these signalling molecules, in the present paper we review the comparative data pointing toward the endocannabinoid involvement in the reproductive control of non-mammalian vertebrates, focussing in particular on the central regulation of teleost and amphibian reproduction. The morphofunctional distribution of brain cannabinoid receptors will be discussed in relation to other crucial signalling molecules involved in the control of reproductive functions, such as GnRH, dopamine, aromatase and pituitary gonadotropins.

Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction

COTTONE, Erika;POMATTO, VALENTINA;BOVOLIN, Patrizia
2013-01-01

Abstract

The endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, i.e. central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the biology of these signalling molecules, in the present paper we review the comparative data pointing toward the endocannabinoid involvement in the reproductive control of non-mammalian vertebrates, focussing in particular on the central regulation of teleost and amphibian reproduction. The morphofunctional distribution of brain cannabinoid receptors will be discussed in relation to other crucial signalling molecules involved in the control of reproductive functions, such as GnRH, dopamine, aromatase and pituitary gonadotropins.
2013
2013
1
8
http://dx.doi.org/10.1155/2013/941237
cannabinoid receptors; teleost; amphibian; GnRH; dopamine; aromatase
Erika Cottone;Valentina Pomatto;Patrizia Bovolin
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/139078
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