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Design, synthesis and co-crystallization of new Plasmodium falciparum dihydroorotate dehydrogenase inhibitors based on hydroxypyrazole scaffold
2019-01-01 Noemi Villella, Agnese Chiara Pippione, Stefano Sainas, Donatella Boschi, Rosmarie Friemann, Alberto Gimenéz, Efrain Salamanca, Marco Lucio Lolli
Design, synthesis, and biological evaluation of flufenamic acid derived bioisosteres as inhibitors of aldo-keto reductase 1C3 (AKR1C3) expressed in prostate cancer
2016-01-01 Lolli, Marco; Cena, Clara; Giraudo, Alessandro; Marini, Elisabetta; Pippione, Agnese; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Sadiq, Maria; Pors, Klaus; Boschi, Donatella; Braga, Rudolpho; Andrade, Carolina.
Development of new hydroxypyrazole-based inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH)
2014-01-01 A.C. Pippione; A. Giraudo; I. Galleano; U.J. Nilsson; I. Fritzson; A.P. Sundin; S. Al-Karadaghi; D. Boschi; M.L. Lolli
Discovery and optimization of new OvCHT1 inhibitors based on the 4-hydroxy-1H-1,2,3-triazole ring
2014-01-01 A. Ducime; A. C. Pippione; A. Moreo; A. Piccinelli; M. Gooyit; K. D. Janda; D. Boschi; M. L. Lolli
Discovery of new NIK inhibitors by Structure-Based Drug Design
2014-01-01 Jean-Marie Contreras; Bo Svensson; Bjorn Walse; Salam Al-Karadaghi; Frank Totzke; Michael H.G. Kubbutat; Christoph Schächtele; Marco Lolli; Donatella Boschi; Marco Piccinini; Elisa Lupino; Joel Sussmann; Israel Silman; Yoav Peleg; Christophe Morice; Thierry Langer
Effects of new hydroxyazoles inhibitors of AKR1C3 on vitality of prostate and colorectal cancer cell lines
2019-01-01 Valentina Boscaro, Donatella Boschi, Simonetta Oliaro-Bosso, Martina Daga, Marco Lolli, Agnese Chiara Pippione, Margherita Gallicchio
Emerging therapies for acute myeloid leukaemia using hDHODH inhibitors
2019-01-01 Sainas Stefano, Pippione Agnese Chiara, Bonanni Davide, Giorgis Marta, Lupino Elisa, Circosta Paola, Gaidano Valentina, Cignetti Alessandro, Piccinini Marco, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio
Emerging therapies for acute myeloid leukaemia using hDHODH inhibitors able to restore in vitro and in vivo myeloid differentiation
2019-01-01 Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Marilena Marraudino, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
Hydroxypyrazolo[1,5-a]pyridine as a fluorescent carboxylic acid isostere: introducing GABAA receptor system affinities in the scaffold
2013-01-01 A. Ducime; B. Nielsen; D. Boschi; B. Frølund; M. L. Lolli
Hydroxypyrazolol[1,5-a]pyridine as a fluorescent carboxylic acid isostere: development of new fluorescent 4-PHP analogues
2013-01-01 Stefano Sainas; Birgitte Nielsen; Donatella Boschi; Bente Frølund; Marco L. Lolli
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Design, synthesis and co-crystallization of new Plasmodium falciparum dihydroorotate dehydrogenase inhibitors based on hydroxypyrazole scaffold | 2019 | Noemi Villella, Agnese Chiara Pippione, Stefano Sainas, Donatella Boschi, Rosmarie Friemann, Alberto Gimenéz, Efrain Salamanca, Marco Lucio Lolli | |
| Design, synthesis, and biological evaluation of flufenamic acid derived bioisosteres as inhibitors of aldo-keto reductase 1C3 (AKR1C3) expressed in prostate cancer | 2016 | Lolli, Marco; Cena, Clara; Giraudo, Alessandro; Marini, Elisabetta; Pippione, Agnese; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Sadiq, Maria; Pors, Klaus; Boschi, Donatella; Braga, Rudolpho; Andrade, Carolina. | |
| Development of new hydroxypyrazole-based inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) | 2014 | A.C. Pippione; A. Giraudo; I. Galleano; U.J. Nilsson; I. Fritzson; A.P. Sundin; S. Al-Karadaghi; D. Boschi; M.L. Lolli | |
| Discovery and optimization of new OvCHT1 inhibitors based on the 4-hydroxy-1H-1,2,3-triazole ring | 2014 | A. Ducime; A. C. Pippione; A. Moreo; A. Piccinelli; M. Gooyit; K. D. Janda; D. Boschi; M. L. Lolli | |
| Discovery of new NIK inhibitors by Structure-Based Drug Design | 2014 | Jean-Marie Contreras; Bo Svensson; Bjorn Walse; Salam Al-Karadaghi; Frank Totzke; Michael H.G. Kubbutat; Christoph Schächtele; Marco Lolli; Donatella Boschi; Marco Piccinini; Elisa Lupino; Joel Sussmann; Israel Silman; Yoav Peleg; Christophe Morice; Thierry Langer | |
| Effects of new hydroxyazoles inhibitors of AKR1C3 on vitality of prostate and colorectal cancer cell lines | 2019 | Valentina Boscaro, Donatella Boschi, Simonetta Oliaro-Bosso, Martina Daga, Marco Lolli, Agnese Chiara Pippione, Margherita Gallicchio | |
| Emerging therapies for acute myeloid leukaemia using hDHODH inhibitors | 2019 | Sainas Stefano, Pippione Agnese Chiara, Bonanni Davide, Giorgis Marta, Lupino Elisa, Circosta Paola, Gaidano Valentina, Cignetti Alessandro, Piccinini Marco, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lucio | |
| Emerging therapies for acute myeloid leukaemia using hDHODH inhibitors able to restore in vitro and in vivo myeloid differentiation | 2019 | Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Marilena Marraudino, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli | |
| Hydroxypyrazolo[1,5-a]pyridine as a fluorescent carboxylic acid isostere: introducing GABAA receptor system affinities in the scaffold | 2013 | A. Ducime; B. Nielsen; D. Boschi; B. Frølund; M. L. Lolli | |
| Hydroxypyrazolol[1,5-a]pyridine as a fluorescent carboxylic acid isostere: development of new fluorescent 4-PHP analogues | 2013 | Stefano Sainas; Birgitte Nielsen; Donatella Boschi; Bente Frølund; Marco L. Lolli |
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Opzioni
Scopri
Tipologia
- 04-CONTRIBUTO IN ATTI DI CONVEGNO 49
- 04-CONTRIBUTO IN ATTI DI CONVEGNO... 49
Data di pubblicazione
- 2020 - 2023 15
- 2012 - 2019 34
Keyword
- bioisosterism 2
- 17β-HSD5 1
- 1H-pyrazole-4-carboxylic acid 1
- AKR1C3 1
- Aldo-keto reductase 1C3 1
- bioisterism 1
- CRPC 1
- hydroxylated heterocyclic 1
- hydroxylated pentatomic heterocyclic 1
- IkB kinase 1
Lingua
- eng 47
- enm 2
Accesso al fulltext
- reserved 24
- no fulltext 16
- open 9