Subthalamic nucleus deep brain stimulation (STN-DBS) has been recently compared to a possible "second therapeutic honeymoon" for Parkinson's disease, as it might prevent the development of severe motor complications and lessen the social adjustment associated to disease progression. This study aims to evaluate whether an early surgical treatment could result in better long-term outcomes, comparing the follow-up evolution of 203 parkinsonian patients, treated at different stages of the disease course.
Earlier versus later subthalamic deep brain stimulation in Parkinson's disease
MEROLA, Aristide;ROMAGNOLO, ALBERTO;RIZZI, Laura;ARTUSI, Carlo Alberto;LANOTTE, Michele Maria Rosario;RIZZONE, Mario Giorgio;Zibetti, Maurizio;LOPIANO, Leonardo
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2015-01-01
Abstract
Subthalamic nucleus deep brain stimulation (STN-DBS) has been recently compared to a possible "second therapeutic honeymoon" for Parkinson's disease, as it might prevent the development of severe motor complications and lessen the social adjustment associated to disease progression. This study aims to evaluate whether an early surgical treatment could result in better long-term outcomes, comparing the follow-up evolution of 203 parkinsonian patients, treated at different stages of the disease course.
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