A serie of 27 N-benzoyl amino acid derivatives were synthesized according to three different approaches (A, B and C moiety), and their ability to inhibit DNMT-dependent total DNA methylation was explored.
Synthesis of Small Molecules as Potential DNA Methylation Modulators
GARELLA, Davide;BRASCHI, ALESSANDRA MARIA;COCCO, MATTIA;GIORGIS, Marta;COSTALE, Annalisa;BERTINARIA, Massimo
2015-01-01
Abstract
A serie of 27 N-benzoyl amino acid derivatives were synthesized according to three different approaches (A, B and C moiety), and their ability to inhibit DNMT-dependent total DNA methylation was explored.
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