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Among 396 HIV-infected women conceiving on combination antiretroviral therapy and enrolled in the European Collaborative Study in 2000-2011, the proportion with virological failure (>200 copies/ml after ≥24 weeks of treatment) declined substantially from 34% in 2000-2001 to 3% in 2010-2011. In adjusted analyses, younger women and those with at least two children were at increased risk of virological failure, highlighting the importance of close monitoring and adherence support.

Improvements in virological control among women conceiving on combination antiretroviral therapy in Western Europe

De Rossi A;DAL MASO, GIULIA;MARTINELLI, Pasquale;AGANGI, ANNA;Masuelli G;Benedetto C;
2013-01-01

Abstract

Among 396 HIV-infected women conceiving on combination antiretroviral therapy and enrolled in the European Collaborative Study in 2000-2011, the proportion with virological failure (>200 copies/ml after ≥24 weeks of treatment) declined substantially from 34% in 2000-2001 to 3% in 2010-2011. In adjusted analyses, younger women and those with at least two children were at increased risk of virological failure, highlighting the importance of close monitoring and adherence support.
2013
AIDS
27
14
2312
2315
Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Europe; Female; HIV Infections; Humans; Medication Adherence; Pregnancy; Treatment Failure; Viral Load; Immunology and Allergy; Immunology; Infectious Diseases
Bailey, Heather*; Townsend, Claire L.; Cortina-Borja, Mario; Thorne, Claire Collaborators (80): Giaquinto C, Rampon O, Mazza A, De Rossi A, Grosch Wörner I, Mok J, de José MI, Larrú Martínez B, Peña JM, Gonzalez Garcia J, Arribas Lopez JR, Garcia Rodriguez MC, Asensi-Botet F, Otero MC, Pérez-Tamarit D, Scherpbier HJ, Kreyenbroek M, Godfried MH, Nellen FJ, Boer K, Navér L, Bohlin AB, Lindgren S, Kaldma A, Belfrage E, Levy J, Barlow P, Manigart Y, Hainaut M, Goetghebuer T, Brichard B, De Camps J, Thiry N, Deboone G, Waterloos H, Viscoli C, De Maria A, Bentivoglio G, Ferrero S, Gotta C, Mûr A, Payà A, López-Vilchez MA, Carreras R, Valerius H, Rosenfeldt V, Coll C, Suy A, Perez JM, Fortuny C, Boguña J, Savasi V, Fiore S, Crivelli M, Viganò A, Giacomet V, Cerini C, Raimondi C, Zuccotti G, Alberico S, Maso G, Airoud N, Taylor GP, Lyall EG, Penn Z, Buffolano W, Tiseo R, Martinelli P, Sansone M, Maruotti G, Agangi A, Tibaldi C, Marini S, Masuelli G, Benedetto C, Niemieç T, Marczynska M, Dobosz S, Popielska J, Oldakowska A.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1677198
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