In the phase 3 KEYNOTE-407 study, the addition of pembrolizumab to carboplatin-paclitaxel/nab-paclitaxel significantly improved overall survival, progression-free survival, and objective response rate in patients with previously untreated metastatic squamous non-small-cell lung cancer (NSCLC), with little impact on severe toxicity. We present patient-reported outcomes (PROs) from KEYNOTE-407.

Health-Related Quality of Life With Carboplatin-Paclitaxel or nab-Paclitaxel With or Without Pembrolizumab in Patients With Metastatic Squamous Non-Small-Cell Lung Cancer

Novello, Silvia;
2019-01-01

Abstract

In the phase 3 KEYNOTE-407 study, the addition of pembrolizumab to carboplatin-paclitaxel/nab-paclitaxel significantly improved overall survival, progression-free survival, and objective response rate in patients with previously untreated metastatic squamous non-small-cell lung cancer (NSCLC), with little impact on severe toxicity. We present patient-reported outcomes (PROs) from KEYNOTE-407.
2019
///
///
Mazieres, Julien; Kowalski, Dariusz; Luft, Alexander; Vicente, David; Tafreshi, Ali; Gümüş, Mahmut; Laktionov, Konstantin; Hermes, Barbara; Cicin, Irfan; Rodríguez-Cid, Jerónimo; Wilson, Jonathan; Kato, Terufumi; Ramlau, Rodryg; Novello, Silvia; Reddy, Sreekanth; Kopp, Hans-Georg; Piperdi, Bilal; Li, Xiaodong; Burke, Thomas; Paz-Ares, Luis
File in questo prodotto:
File Dimensione Formato  
Health-Related Quality of Life With Carboplatin-Paclitaxel or nab-Paclitaxel With or Without Pembrolizumab in Patients With Metastatic Squamous Non–Small-Cell Lung Cancer.pdf

Accesso aperto

Tipo di file: PDF EDITORIALE
Dimensione 901.72 kB
Formato Adobe PDF
901.72 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1720827
Citazioni
  • ???jsp.display-item.citation.pmc??? 34
  • Scopus 56
  • ???jsp.display-item.citation.isi??? 54
social impact