The present invention provides novel human antigens and related antibodies that have been identified as being specifically expressed in association to huma Pancreatic Ductal Adenocarcinoma (PDA). In particular, novel phosphorylation isoforms of alpha-enolase have been identified in transformed cell lines of pancreatic origin and antibodies binding such isoforms are specifically present in the sera of PDA patients. The proteins and antibodies can be used for the dagnosis and tratment of PDA and other cancers havingcommon molecular features

Novel antigens and antibodies associated to pancreatic ductal adenocarcinoma

NOVELLI, Francesco;CAPPELLO, Paola
2007-01-01

Abstract

The present invention provides novel human antigens and related antibodies that have been identified as being specifically expressed in association to huma Pancreatic Ductal Adenocarcinoma (PDA). In particular, novel phosphorylation isoforms of alpha-enolase have been identified in transformed cell lines of pancreatic origin and antibodies binding such isoforms are specifically present in the sera of PDA patients. The proteins and antibodies can be used for the dagnosis and tratment of PDA and other cancers havingcommon molecular features
2007
WO2008/037792A1
Ribovax SA (CH); Bioline diagnostici srl (IT)
adenocarcinoma pancreatico; uomo; antigeni associati al tumore; proteomica; anticorpi; diagnosi; prognosi
F. NOVELLI; B. TOMAINO; P. CAPPELLO
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/27214
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