Our study shows evidences that CCl4 administration (at the dose of 2,5 ml/kg b.w. 'per os') increased ATPase activities in rat liver plasmamembranes 1 and 2 hours after treatment. Conversely we found that CCl4 poisoning decreased ATPase activities in microsomal membranes of rat liver at the same tested times. Therefore we suggest that ATPase activities were differently influenced by CCl4 treatment with respect to different subcellular distribution of those enzymes.
[Changes in adenosinetriphosphatase activity in rat liver after CC14 poisoning]
BARRERA, Giuseppina;PAROLA, Maurizio;PARADISI, Luciana;DIANZANI, Mario Umberto
1982-01-01
Abstract
Our study shows evidences that CCl4 administration (at the dose of 2,5 ml/kg b.w. 'per os') increased ATPase activities in rat liver plasmamembranes 1 and 2 hours after treatment. Conversely we found that CCl4 poisoning decreased ATPase activities in microsomal membranes of rat liver at the same tested times. Therefore we suggest that ATPase activities were differently influenced by CCl4 treatment with respect to different subcellular distribution of those enzymes.
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