A new HLA-DRB5 allele, HLA-DRB5*0113, has been identified in an Italian patient during routine HLA typing in order to activate a bone marrow donor search. HLA typing was performed by different molecular biology techniques, and the results showed that the HLA-DRB5*0113 allele differs from HLA-DRB5*010101 allele for three nucleotide substitutions at codons 57 (GAC-->GAT; Asp) and 58 (GCT-->GAG; Ala-->Glu) of exon 2.

Identification of a new allele, HLA-DRB5*0113, through three different molecular biology techniques

BERTINETTO, FRANCESCA;FRISALDI, ELISA;TONDAT, FABRIZIO;BOCCADORO, Mario;BRUNO, Benedetto;AMOROSO, Antonio
2006-01-01

Abstract

A new HLA-DRB5 allele, HLA-DRB5*0113, has been identified in an Italian patient during routine HLA typing in order to activate a bone marrow donor search. HLA typing was performed by different molecular biology techniques, and the results showed that the HLA-DRB5*0113 allele differs from HLA-DRB5*010101 allele for three nucleotide substitutions at codons 57 (GAC-->GAT; Asp) and 58 (GCT-->GAG; Ala-->Glu) of exon 2.
2006
67(5)
427
429
http://www3.interscience.wiley.com/cgi-bin/fulltext/118585882/PDFSTART
allele; high resolution; human leucocyte antigen; low resolution; polymerase chain reaction-sequence specific oligonucleotides probe; polymerase chain reaction-sequence specific primers; sequence-based typing
GARINO E; BERRINO M; BERTINETTO F; CAROPRESO P; CHIDICHIMO R; DAMETTO E; FASANO ME; FRISALDI E; MAZZOLA G; TONDAT F; BOCCADORO M; BRUNO B; AMOROSO A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/36896
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