This research aimed to improve the loading capacity and the physical stability of liposomes containing docetaxel in comparison with paclitaxel. Several formulations of docetaxel liposomes have been studied. Entrapment efficiency and docetaxel concentration of liposomal formulations have been increased. Growth inhibitory activity of taxanes on two different human cancer cell lines was compared to that of taxane-liposomes.

Preparazione e caratterizzazione di liposomi convenzionali ed a lunga circolazione contenenti taxani

IMMORDINO, Maria Laura;BRUSA, Paola;STELLA, Barbara;ARPICCO, Silvia Maria;DOSIO, Franco;CATTEL, Luigi
2001-01-01

Abstract

This research aimed to improve the loading capacity and the physical stability of liposomes containing docetaxel in comparison with paclitaxel. Several formulations of docetaxel liposomes have been studied. Entrapment efficiency and docetaxel concentration of liposomal formulations have been increased. Growth inhibitory activity of taxanes on two different human cancer cell lines was compared to that of taxane-liposomes.
2001
12
101
107
Anticancer agents; liposomes; encapsulation; stability
IMMORDINO ML; BRUSA P; STELLA B; ARPICCO S; DOSIO F; CATTEL L
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/4912
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