Relevance of symptoms versus objective evidences in neonatal grastroesophageal reflux disease

Gastroesophageal reflux disease (GERD) in newborn is characterized by a protean symptomatology that includes excessive irritability and crying, frequent vomiting and regurgitations, feeding problems, rumination, apnea, aspiration pneumonia, failure te thrive and anemia. The aim of this study was to investigate the relationship between symptorns and gastroesophageal activity in infants with gastroesophageal reflux. Conclusions: Our data suggest a relationship between GER symptoms and gastroesophageal activity. These findings could be relevant to practice of giving neonatal GERD therapeutic treaonents on the grounds of infants symptoms. Further studies are necessary to establish the impact of our results and a possible clinical utilization.