BACKGROUND: Few studies have addressed predictors of long-term mortality after first-ever ischaemic stroke. METHODS: We prospectively collected data on 361 consecutive patients admitted to 18 neurology departments in Italy for a first-ever ischaemic stroke in 1999, categorized according to the Oxfordshire Community Stroke Project (OCSP) classification. Age, gender, risk factors, previous vascular disease, in-hospital complications, stroke severity, functional status, therapy and living place at admission, discharge and after 6 months were recorded. Follow-up was available for 97\% patients at 5 years. RESULTS: Survival probability was 91\% (95\% CI = 88-94) at 1 month, 84\% (80-88) at 6 months and 64\% (58-69) at 5 years. Mortality was higher for the TACI (total anterior circulation infarct) group compared to the other categories (p < 0.0001). Hazard ratios for 5-year mortality in the final model were: 5.4 for age >or=65 years (p < 0.0001), 2.8 for TACI (p < 0.0001), 2.7 for previous vascular disease (p < 0.01) and 1.9 for cardio-embolic risk according to the TOAST risk stratification (p < 0.05). CONCLUSIONS: Our study extends the prognostic value of the OCSP classification to 5-year survival.

Five-year survival after first-ever ischaemic stroke is worse in total anterior circulation infarcts: the SINPAC cohort.

PRIANO, LORENZO;Rudà R;
2009-01-01

Abstract

BACKGROUND: Few studies have addressed predictors of long-term mortality after first-ever ischaemic stroke. METHODS: We prospectively collected data on 361 consecutive patients admitted to 18 neurology departments in Italy for a first-ever ischaemic stroke in 1999, categorized according to the Oxfordshire Community Stroke Project (OCSP) classification. Age, gender, risk factors, previous vascular disease, in-hospital complications, stroke severity, functional status, therapy and living place at admission, discharge and after 6 months were recorded. Follow-up was available for 97\% patients at 5 years. RESULTS: Survival probability was 91\% (95\% CI = 88-94) at 1 month, 84\% (80-88) at 6 months and 64\% (58-69) at 5 years. Mortality was higher for the TACI (total anterior circulation infarct) group compared to the other categories (p < 0.0001). Hazard ratios for 5-year mortality in the final model were: 5.4 for age >or=65 years (p < 0.0001), 2.8 for TACI (p < 0.0001), 2.7 for previous vascular disease (p < 0.01) and 1.9 for cardio-embolic risk according to the TOAST risk stratification (p < 0.05). CONCLUSIONS: Our study extends the prognostic value of the OCSP classification to 5-year survival.
2009
27
29
36
http://dx.doi.org/10.1159/000172631
Aged; 80 and over; Brain Ischemia; Cerebral Hemorrhage; Cohort Studies; Female; Humans; Infarction; Anterior Cerebral Artery; Length of Stay; Male; Middle Aged; Predictive Value of Tests; Prognosis; Risk Factors; Stroke; Survival Analysis
M. Reggiani;S. I. Piemonte e Valle d'Aosta per le Cerebrovasculopatie Group; Sciolla R; Ferrari G; Cerrato P; Labate C; Priano L; Leone M; Appiotti A; Priano L; Gruppallo F; Cerrato P; Verdun E; Doriguzzi C; Magliola U; Pipieri A; Bottacchi E; Corso G; D'Alessandro G; De Mattei M; Rudà R; Ferrari G; Enrico E; Maggio M; Giobbe D; Palmiero R; Calvi L; Grasso E; Gerbino-Promis PC; Meineri P; Terazzi E; Mittino D; Sciolla R; Gai P; Buffa C; Cordera S; Rocci E; Liboni W; Pavanelli E; Oddenino E; Villani A; Conte R; Labate C; Cristofanelli P; Provera P; Gilardengo P; Dutto A; Gagliano A; Cognazzo A; Nobili M; Zurlo F; Vivalda L; Ravetti C; Lovera N; Chianale G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/75954
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