We present a device consisting in a 3x3 microelectrode array (MEA) of boron-doped nanocrystalline diamond (NCD) on sapphire for the electrochemical detection of molecules released from membrane micro-areas of single excitable and secretory cells. The MEA has been tested in liquid environment containing the standard red-ox couple for diamond testing Fe(CN)6 4-/3- and with adrenaline, confirming the suitability of the device for high sensitivity and high spatial resolution electrophysiological analysis on single cells.
Transparent NCD microelectrode array for spatially resolved detection in micro-areas of single ce
CARABELLI, Valentina;CARBONE, Emilio;
2010-01-01
Abstract
We present a device consisting in a 3x3 microelectrode array (MEA) of boron-doped nanocrystalline diamond (NCD) on sapphire for the electrochemical detection of molecules released from membrane micro-areas of single excitable and secretory cells. The MEA has been tested in liquid environment containing the standard red-ox couple for diamond testing Fe(CN)6 4-/3- and with adrenaline, confirming the suitability of the device for high sensitivity and high spatial resolution electrophysiological analysis on single cells.
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