Sfoglia per Autore
NLRP3 INFLAMMASOME-inhibiting compounds and the use thereof
2022-01-01 Blandizzi Corrado, Pellegrini Carolina, Fornai Matteo, Antonioli Luca, Colucci Rocchina, Bertinaria Massimo, Marini Elisabetta, Boscaro Valentina, Gastaldi Simone, Cocco Mattia
COMPOSTI INIBITORI DELL’INFLAMMASOMA NLRP3 E LORO USO
2021-01-01 BLANDIZZI CORRADO, PELLEGRINI CAROLINA, FORNAI MATTEO, ANTONIOLI LUCA, COLUCCI ROCCHINA, BERTINARIA MASSIMO, MARINI ELISABETTA, BOSCARO VALENTINA, GASTALDI SIMONE, COCCO MATTIA
Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells from Type2 Diabetes Patients: Rescue by alpha Ketoglutarate and TET-TDG Functional Reactivation
2018-01-01 Spallotta, Francesco; Cencioni, Chiara; Atlante, Sandra; Garella, Davide; Cocco, Mattia; Mori, Mattia; Mastrocola, Raffaella; Kuenne, Carsten; Guenther, Stefan; Nanni, Simona; Azzimato, Valerio; Zukunft, Sven; Kornberger, Angela; Sã¼rã¼n, Duran; Schnã¼tgen, Frank; Von Melchner, Harald; Di Stilo, Antonella; Aragno, Manuela; Braspenning, Maarten; Van Criekinge, Wim; De Blasio, Miles J.; Ritchie, Rebecca H.; Zaccagnini, Germana; Martelli, Fabio; Farsetti, Antonella; Fleming, Ingrid; Braun, Thomas; Beiras-Fernandez, Andres; Botta, Bruno; Collino, Massimo; Bertinaria, Massimo; Zeiher, Andreas M.; Gaetano, Carlo
Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease
2017-01-01 Cocco, Mattia; Pellegrini, Carolina; Martínez-Banaclocha, Helios; Giorgis, Marta; Marini, Elisabetta; Costale, Annalisa; Miglio, Gianluca; Fornai, Matteo; Antonioli, Luca; López-Castejón, Gloria; Tapia-Abellán, Ana; Angosto, Diego; Hafner-Bratkovič, Iva; Regazzoni, Luca; Blandizzi, Corrado; Pelegrín, Pablo; Bertinaria, Massimo
Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome Inhibitors
2016-01-01 Cocco, Mattia; Miglio, Gianluca; Giorgis, Marta; Garella, Davide; Marini, Elisabetta; Costale, Annalisa; Regazzoni, Luca; Vistoli, Giulio; Orioli, Marica; Massulaha-Ahmed, Raïhane; Détraz-Durieux, Isabelle; Groslambert, Marine; Py, Bénédicte F.; Bertinaria, Massimo
Pharmacological inhibition of NLRP3 inflammasome attenuates myocardial ischemia/reperfusion injury by activation of RISK and mitochondrial pathways
2016-01-01 Mastrocola, Raffaella; Penna, Claudia; Tullio, Francesca; Femminò, Saveria; Nigro, Debora; Chiazza, Fausto; Serpe, Loredana; Collotta, Debora; Alloatti, Giuseppe; Cocco, Mattia; Bertinaria, Massimo; Pagliaro, Pasquale; Aragno, Manuela; Collino, Massimo
Design and synthesis of N-benzoyl amino acid derivatives as DNA methylation inhibitors
2016-01-01 Garella, Davide; Atlante, Sandra; Borretto, Emily; Cocco, Mattia; Giorgis, Marta; Costale, Annalisa; Stevanato, Livio; Miglio, Gianluca; Cencioni, Chiara; Fernández de Gortari, Eli; Medina Franco, José L.; Spallotta, Francesco; Gaetano, Carlo; Bertinaria, Massimo
Cardiac Epi-Metabolic Signature Revealed by Integrated Omics Approach in Diabetic Patients: Rescue by Active DNA Demethylation via TET-TDG Complex Reactivation
2016-01-01 Spallotta, F; Cencioni, C; Atlante, S; Garella, D; Cocco, M; Mori, M; Mastrocola, R; Kuenne, C; Guenther, S; Nanni, S; Azzimato, V; Zukunft, S; Kornberger, A; Di Stilo, A; Aragno, M; Martelli, F; Farsetti, A; Fleming, I; Braun, T; Beiras-Fernandez, A; Botta, B; Collino, M; Bertinaria, M; Zeiher, Am; Gaetano, C.
Targeting of NLRP3 Inflammasome With a Novel Selective Inhibitor as a Suitable Strategy for the Pharmacological Treatment of Bowel Inflammation
2016-01-01 Pellegrini C.; Fornai M.; Colucci R.; Lopez-Castejon G.; Cocco M.; Garella D.; Bertinaria M.; Blandizzi C.; Antonioli L
Is NLRP3 inflammasome a new pharmacological target in myocardial ischemia/reperfusion injury?
2015-01-01 Femminò, S; Chiazza, F; Mastrocola, R; Tullio, F; Penna, C; Nigro, D; Alloatti, G; Cocco, M; Garella, D; Bertinaria, M; Fantozzi, R; Aragno, M; Collino, M; Pagliaro, P
Synthesis of Small Molecules as Potential DNA Methylation Modulators
2015-01-01 Garella, Davide; Braschi, Alessandra Maria; Cocco, Mattia; Giorgis, Marta; Costale, Annalisa; Stilo, Antonella Di; Atlante, Sandra; Gaetano, Carlo; Bertinaria, Massimo
Design, Synthesis and Pharmacological Evaluation of Anti-Pyroptotic Compounds Acting on NLRP3 Inflammasome Signaling Pathway: a New Start for Anti-Inflammatory Drugs?
2014-01-01 Bertinaria Massimo; Cocco Mattia; Garella Davide; Marini Elisabetta; Di Stilo Antonella; Miglio Gianluca
Electrophilic Warhead-Based Design of Compounds Preventing NLRP3 Inflammasome-Dependent Pyroptosis
2014-01-01 Mattia Cocco; Davide Garella; Antonella Di Stilo; Emily Borretto; Livio Stevanato; Marta Giorgis; Elisabetta Marini; Roberto Fantozzi; Gianluca Miglio; Massimo Bertinaria
Targeting NLRP3 inflammasome regulatory mechanisms: design of anti-pyroptotic compounds for autoinflammatory diseases
2014-01-01 Massimo Bertinaria; Mattia Cocco; Davide Garella; Marta Giorgis; Antonella Di Stilo; Gianluca Miglio
Use of the Morita-Baylis-Hillman reaction in the design of compounds inhibiting NLRP3 inflammasome signaling pathways
2014-01-01 M. Cocco; D. Garella; G. Miglio; E. Borretto; L. Stevanato; A. Di Stilo; M. Bertinaria
Synthesis and preliminary evaluation of model compounds targeting the NLRP3 inflammasome pathways
2013-01-01 Davide Garella; Mattia Cocco; Antonella Di Stilo; Gianluca Miglio; Massimo Collino; Roberto Fantozzi; Massimo Bertinaria
Identification of Small Synthetic Anti-Pyroptotic Compounds
2013-01-01 G. Miglio; M. Bertinaria; M. Rogazzo; M. Cocco; D. Garella; A. Di Stilo; R. Fantozzi
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| NLRP3 INFLAMMASOME-inhibiting compounds and the use thereof | 2022 | Blandizzi Corrado, Pellegrini Carolina, Fornai Matteo, Antonioli Luca, Colucci Rocchina, Bertinaria Massimo, Marini Elisabetta, Boscaro Valentina, Gastaldi Simone, Cocco Mattia | |
| COMPOSTI INIBITORI DELL’INFLAMMASOMA NLRP3 E LORO USO | 2021 | BLANDIZZI CORRADO, PELLEGRINI CAROLINA, FORNAI MATTEO, ANTONIOLI LUCA, COLUCCI ROCCHINA, BERTINARIA MASSIMO, MARINI ELISABETTA, BOSCARO VALENTINA, GASTALDI SIMONE, COCCO MATTIA | |
| Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells from Type2 Diabetes Patients: Rescue by alpha Ketoglutarate and TET-TDG Functional Reactivation | 2018 | Spallotta, Francesco; Cencioni, Chiara; Atlante, Sandra; Garella, Davide; Cocco, Mattia; Mori, Mattia; Mastrocola, Raffaella; Kuenne, Carsten; Guenther, Stefan; Nanni, Simona; Azzimato, Valerio; Zukunft, Sven; Kornberger, Angela; Sã¼rã¼n, Duran; Schnã¼tgen, Frank; Von Melchner, Harald; Di Stilo, Antonella; Aragno, Manuela; Braspenning, Maarten; Van Criekinge, Wim; De Blasio, Miles J.; Ritchie, Rebecca H.; Zaccagnini, Germana; Martelli, Fabio; Farsetti, Antonella; Fleming, Ingrid; Braun, Thomas; Beiras-Fernandez, Andres; Botta, Bruno; Collino, Massimo; Bertinaria, Massimo; Zeiher, Andreas M.; Gaetano, Carlo | |
| Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease | 2017 | Cocco, Mattia; Pellegrini, Carolina; Martínez-Banaclocha, Helios; Giorgis, Marta; Marini, Elisabetta; Costale, Annalisa; Miglio, Gianluca; Fornai, Matteo; Antonioli, Luca; López-Castejón, Gloria; Tapia-Abellán, Ana; Angosto, Diego; Hafner-Bratkovič, Iva; Regazzoni, Luca; Blandizzi, Corrado; Pelegrín, Pablo; Bertinaria, Massimo | |
| Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome Inhibitors | 2016 | Cocco, Mattia; Miglio, Gianluca; Giorgis, Marta; Garella, Davide; Marini, Elisabetta; Costale, Annalisa; Regazzoni, Luca; Vistoli, Giulio; Orioli, Marica; Massulaha-Ahmed, Raïhane; Détraz-Durieux, Isabelle; Groslambert, Marine; Py, Bénédicte F.; Bertinaria, Massimo | |
| Pharmacological inhibition of NLRP3 inflammasome attenuates myocardial ischemia/reperfusion injury by activation of RISK and mitochondrial pathways | 2016 | Mastrocola, Raffaella; Penna, Claudia; Tullio, Francesca; Femminò, Saveria; Nigro, Debora; Chiazza, Fausto; Serpe, Loredana; Collotta, Debora; Alloatti, Giuseppe; Cocco, Mattia; Bertinaria, Massimo; Pagliaro, Pasquale; Aragno, Manuela; Collino, Massimo | |
| Design and synthesis of N-benzoyl amino acid derivatives as DNA methylation inhibitors | 2016 | Garella, Davide; Atlante, Sandra; Borretto, Emily; Cocco, Mattia; Giorgis, Marta; Costale, Annalisa; Stevanato, Livio; Miglio, Gianluca; Cencioni, Chiara; Fernández de Gortari, Eli; Medina Franco, José L.; Spallotta, Francesco; Gaetano, Carlo; Bertinaria, Massimo | |
| Cardiac Epi-Metabolic Signature Revealed by Integrated Omics Approach in Diabetic Patients: Rescue by Active DNA Demethylation via TET-TDG Complex Reactivation | 2016 | Spallotta, F; Cencioni, C; Atlante, S; Garella, D; Cocco, M; Mori, M; Mastrocola, R; Kuenne, C; Guenther, S; Nanni, S; Azzimato, V; Zukunft, S; Kornberger, A; Di Stilo, A; Aragno, M; Martelli, F; Farsetti, A; Fleming, I; Braun, T; Beiras-Fernandez, A; Botta, B; Collino, M; Bertinaria, M; Zeiher, Am; Gaetano, C. | |
| Targeting of NLRP3 Inflammasome With a Novel Selective Inhibitor as a Suitable Strategy for the Pharmacological Treatment of Bowel Inflammation | 2016 | Pellegrini C.; Fornai M.; Colucci R.; Lopez-Castejon G.; Cocco M.; Garella D.; Bertinaria M.; Blandizzi C.; Antonioli L | |
| Is NLRP3 inflammasome a new pharmacological target in myocardial ischemia/reperfusion injury? | 2015 | Femminò, S; Chiazza, F; Mastrocola, R; Tullio, F; Penna, C; Nigro, D; Alloatti, G; Cocco, M; Garella, D; Bertinaria, M; Fantozzi, R; Aragno, M; Collino, M; Pagliaro, P | |
| Synthesis of Small Molecules as Potential DNA Methylation Modulators | 2015 | Garella, Davide; Braschi, Alessandra Maria; Cocco, Mattia; Giorgis, Marta; Costale, Annalisa; Stilo, Antonella Di; Atlante, Sandra; Gaetano, Carlo; Bertinaria, Massimo | |
| Design, Synthesis and Pharmacological Evaluation of Anti-Pyroptotic Compounds Acting on NLRP3 Inflammasome Signaling Pathway: a New Start for Anti-Inflammatory Drugs? | 2014 | Bertinaria Massimo; Cocco Mattia; Garella Davide; Marini Elisabetta; Di Stilo Antonella; Miglio Gianluca | |
| Electrophilic Warhead-Based Design of Compounds Preventing NLRP3 Inflammasome-Dependent Pyroptosis | 2014 | Mattia Cocco; Davide Garella; Antonella Di Stilo; Emily Borretto; Livio Stevanato; Marta Giorgis; Elisabetta Marini; Roberto Fantozzi; Gianluca Miglio; Massimo Bertinaria | |
| Targeting NLRP3 inflammasome regulatory mechanisms: design of anti-pyroptotic compounds for autoinflammatory diseases | 2014 | Massimo Bertinaria; Mattia Cocco; Davide Garella; Marta Giorgis; Antonella Di Stilo; Gianluca Miglio | |
| Use of the Morita-Baylis-Hillman reaction in the design of compounds inhibiting NLRP3 inflammasome signaling pathways | 2014 | M. Cocco; D. Garella; G. Miglio; E. Borretto; L. Stevanato; A. Di Stilo; M. Bertinaria | |
| Synthesis and preliminary evaluation of model compounds targeting the NLRP3 inflammasome pathways | 2013 | Davide Garella; Mattia Cocco; Antonella Di Stilo; Gianluca Miglio; Massimo Collino; Roberto Fantozzi; Massimo Bertinaria | |
| Identification of Small Synthetic Anti-Pyroptotic Compounds | 2013 | G. Miglio; M. Bertinaria; M. Rogazzo; M. Cocco; D. Garella; A. Di Stilo; R. Fantozzi |
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