Sfoglia per Autore
AMPK activation attenuates HER3 upregulation and Neuregulin-Mediated rescue of cell proliferation in HER2-Overexpressing breast cancer cell lines exposed to lapatinib
2022-01-01 Barbara Buccinnà; Cristina Ramondetti; Marco Piccinini.
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety
2022-01-01 Sainas, Stefano; Giorgis, Marta; Circosta, Paola; Poli, Giulio; Alberti, Marta; Passoni, Alice; Gaidano, Valentina; Pippione, Agnese C; Vitale, Nicoletta; Bonanni, Davide; Rolando, Barbara; Cignetti, Alessandro; Ramondetti, Cristina; Lanno, Alessia; Ferraris, Davide M; Canepa, Barbara; Buccinnà, Barbara; Piccinini, Marco; Rizzi, Menico; Saglio, Giuseppe; Al-Karadaghi, Salam; Boschi, Donatella; Miggiano, Riccardo; Tuccinardi, Tiziano; Lolli, Marco L
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold: SAR of the Biphenyl Moiety
2021-01-01 Sainas S.; Giorgis M.; Circosta P.; Gaidano V.; Bonanni D.; Pippione A.C.; Bagnati R.; Passoni A.; Qiu Y.; Cojocaru C.F.; Canepa B.; Bona A.; Rolando B.; Mishina M.; Ramondetti C.; Buccinna B.; Piccinini M.; Houshmand M.; Cignetti A.; Giraudo E.; Al-Karadaghi S.; Boschi D.; Saglio G.; Lolli M.L.
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors
2018-01-01 Sainas, Stefano; Pippione, Agnese C; Lupino, Elisa; Giorgis, Marta; Circosta, Paola; Gaidano, Valentina; Goyal, Parveen; Bonanni, Davide; Rolando, Barbara; Cignetti, Alessandro; Ducime, Alex; Andersson, Mikael; Järvå, Michael; Friemann, Rosmarie; Piccinini, Marco; Ramondetti, Cristina; Buccinnà, Barbara; Al-Karadaghi, Salam; Boschi, Donatella; Saglio, Giuseppe; Lolli, Marco L
Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds
2017-01-01 Sainas, Stefano; Pippione, Agnese C.; Giorgis, Marta; Lupino, Elisa; Goyal, Parveen; Ramondetti, Cristina; Buccinnà, Barbara; Piccinini, Marco; Braga, Rodolpho C.; Andrade, Carolina H.; Andersson, Mikael; Moritzer, Ann-Christin; Friemann, Rosmarie; Mensa, Stefano; Al-Kadaraghi, Salam; Boschi, Donatella; Lolli, Marco L
Exposure of neuroblastoma cell lines to imatinib results in the upregulation of the CDK inhibitor p27KIP1 as a consequence of c-Abl inhibition
2014-01-01 E. Lupino; C. Ramondetti; B. Buccinnà; M. Piccinini
Reduced cellular Ca(2+) availability enhances TDP-43 cleavage by apoptotic caspases.
2014-01-01 G. De Marco; A. Lomartire; G. Mandili; E. Lupino; B. Buccinnà; C. Ramondetti; C. Moglia; F. Novelli; M. Piccinini; M. Mostert; MT Rinaudo; A. Chiò; A. Calvo
Increased cytoplasmic mislocalization of TAR DNA binding protein 43 (TDP-43) in circulating lymphomonocytes of ALS patients recapitulates the major dysfunction featuring motor neurons in the disease.
2011-01-01 De Marco G; Lupino E; Grifoni S; Calvo A; Moglia C; Buccinnà B; Ramondetti C; Lomartire A; Piccinini M; Rinaudo MT;Giordana MT; Chiò A.
Novel dysfunctions at the origin of hypomyelination, a feature of Niemann Pick type A
2011-01-01 Buccinnà B; Lomartire A; Ramondetti C; De Marco G; Rinaudo MT; Lupino E; Piccinini M
Cytoplasmic accumulation of TDP-43 in circulating lymphomonocytes of ALS patients with and without TARDBP mutations
2011-01-01 De Marco G; Lupino E; Calvo A; Moglia C; Buccinnà B; Grifoni S; Ramondetti C; Lomartire A; Rinaudo MT; Piccinini M; Giordana MT; Chiò A.
In CD28-costimulated human naïve CD4(+) T cells, I-κB kinase controls the expression of cell cycle regulatory proteins via interleukin-2-independent mechanisms
2010-01-01 Lupino E; Buccinnà B; Ramondetti C; Lomartire A; De Marco G; Ricotti E; Tovo PA; Rinaudo MT; Piccinini M
Deregulated Sphingolipid Metabolism and Membrane Organization in Neurodegenerative Disorders
2010-01-01 Piccinini Marco; Scandroglio Federica; Prioni Simona; Buccinnà Barbara; Loberto Nicoletta; Aureli Massimo; Chigorno Vanna; Lupino Elisa; Demarco Giovanni; Lomartire Annarosa; Rinaudo Maria Teresa; Sonnino Sandro; Prinetti Alessandro.
TDP-43 Redistribution Is an Early Event in Sporadic Amyotrophic Lateral Sclerosis
2010-01-01 Giordana MT; Piccinini M; Grifoni S; De Marco G; Vercellino M; Magistrello M; Pellerino A; Buccinnà B; Lupino E; Rinaudo MT.
N-CAM Dysfunction and Unexpected Accumulation of PSA-NCAM in Brain of Adult-Onset Autosomal-Dominant Leukodystrophy.
2010-01-01 Piccinini Marco; Buccinnà Barbara; De Marco Giovanni; Lupino Elisa; Ramondetti Cristina; Grifoni Silvia; Votta Barbara; Giordana Maria Teresa; Rinaudo Maria Teresa
TDP-43 redistribution is an early event in sporadic amyotrophic lateral sclerosis
2009-01-01 Giordana MT; Piccinini M; Grifoni S; De Marco G; Vercellino M; Magistrello M; Pellerino A; Buccinnà B; Lupino E; Rinaudo M T
The expression pattern of TAR DNA-binding protein 43 (TDP-43) in peripheral blood mononuclear cells (PBMC) in individuals affected by amyotrophific lateral sclerosis (ALS) and their healthy relatives
2009-01-01 De Marco G; Piccinini M; Lupino E; Lomartire A; Buccinnà B; Ramondetti C; Grifoni S; Giordana MT; Rinaudo MT
An approach to the timing of altered localization of TDP-43 in ALS motor neurons during disease progression
2009-01-01 Giordana MT; Grifoni S; Piccinini M; Pellerino A; De Marco G ; Buccinnà B ; Lupino E ; Naldi A; Magistrello M; Rinaudo MT
Dysfunctions in N_CAM and unexpected accumulation of PSA_NCAM in brain of Autosomal dominant adult onset leukodystrophy (ADLD)
2009-01-01 Buccinnà B; De Marco G; Piccinini M; Lupino E; Lomartire A; Ramondetti C; Grifoni S; Giordana MT; Rinaudo MT
Alterations of myelin-specific proteins and sphingolipids characterize the brains of acid sphingomyelinase-deficient mice, an animal model of niemannpick disease type A
2009-01-01 Barbara Buccinnà; Marco Piccinini; Alessandro Prinetti; Federica Scandroglio; Simona Prioni; Manuela Valsecchi; Barbara Votta; Silvia Grifoni; Elisa Lupino; Cristina Ramondetti; Edward H. Schuchman; Maria Teresa Giordana; Sandro Sonnino; Maria Teresa Rinaudo
Alterations of protein and lipid patterns in brain white matter of ASMKO mice, the animal model of Niemann-Pick disease type A
2009-01-01 Piccinini M; Buccinnà B; Prinetti A; Scandroglio F; Prioni S; Valsecchi M; Lupino E; Ramondetti C; Sonnino S; Rinaudo MT
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| AMPK activation attenuates HER3 upregulation and Neuregulin-Mediated rescue of cell proliferation in HER2-Overexpressing breast cancer cell lines exposed to lapatinib | 2022 | Barbara Buccinnà; Cristina Ramondetti; Marco Piccinini. | |
| Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety | 2022 | Sainas, Stefano; Giorgis, Marta; Circosta, Paola; Poli, Giulio; Alberti, Marta; Passoni, Alice; Gaidano, Valentina; Pippione, Agnese C; Vitale, Nicoletta; Bonanni, Davide; Rolando, Barbara; Cignetti, Alessandro; Ramondetti, Cristina; Lanno, Alessia; Ferraris, Davide M; Canepa, Barbara; Buccinnà, Barbara; Piccinini, Marco; Rizzi, Menico; Saglio, Giuseppe; Al-Karadaghi, Salam; Boschi, Donatella; Miggiano, Riccardo; Tuccinardi, Tiziano; Lolli, Marco L | |
| Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold: SAR of the Biphenyl Moiety | 2021 | Sainas S.; Giorgis M.; Circosta P.; Gaidano V.; Bonanni D.; Pippione A.C.; Bagnati R.; Passoni A.; Qiu Y.; Cojocaru C.F.; Canepa B.; Bona A.; Rolando B.; Mishina M.; Ramondetti C.; Buccinna B.; Piccinini M.; Houshmand M.; Cignetti A.; Giraudo E.; Al-Karadaghi S.; Boschi D.; Saglio G.; Lolli M.L. | |
| Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors | 2018 | Sainas, Stefano; Pippione, Agnese C; Lupino, Elisa; Giorgis, Marta; Circosta, Paola; Gaidano, Valentina; Goyal, Parveen; Bonanni, Davide; Rolando, Barbara; Cignetti, Alessandro; Ducime, Alex; Andersson, Mikael; Järvå, Michael; Friemann, Rosmarie; Piccinini, Marco; Ramondetti, Cristina; Buccinnà, Barbara; Al-Karadaghi, Salam; Boschi, Donatella; Saglio, Giuseppe; Lolli, Marco L | |
| Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds | 2017 | Sainas, Stefano; Pippione, Agnese C.; Giorgis, Marta; Lupino, Elisa; Goyal, Parveen; Ramondetti, Cristina; Buccinnà, Barbara; Piccinini, Marco; Braga, Rodolpho C.; Andrade, Carolina H.; Andersson, Mikael; Moritzer, Ann-Christin; Friemann, Rosmarie; Mensa, Stefano; Al-Kadaraghi, Salam; Boschi, Donatella; Lolli, Marco L | |
| Exposure of neuroblastoma cell lines to imatinib results in the upregulation of the CDK inhibitor p27KIP1 as a consequence of c-Abl inhibition | 2014 | E. Lupino; C. Ramondetti; B. Buccinnà; M. Piccinini | |
| Reduced cellular Ca(2+) availability enhances TDP-43 cleavage by apoptotic caspases. | 2014 | G. De Marco; A. Lomartire; G. Mandili; E. Lupino; B. Buccinnà; C. Ramondetti; C. Moglia; F. Novelli; M. Piccinini; M. Mostert; MT Rinaudo; A. Chiò; A. Calvo | |
| Increased cytoplasmic mislocalization of TAR DNA binding protein 43 (TDP-43) in circulating lymphomonocytes of ALS patients recapitulates the major dysfunction featuring motor neurons in the disease. | 2011 | De Marco G; Lupino E; Grifoni S; Calvo A; Moglia C; Buccinnà B; Ramondetti C; Lomartire A; Piccinini M; Rinaudo MT;Giordana MT; Chiò A. | |
| Novel dysfunctions at the origin of hypomyelination, a feature of Niemann Pick type A | 2011 | Buccinnà B; Lomartire A; Ramondetti C; De Marco G; Rinaudo MT; Lupino E; Piccinini M | |
| Cytoplasmic accumulation of TDP-43 in circulating lymphomonocytes of ALS patients with and without TARDBP mutations | 2011 | De Marco G; Lupino E; Calvo A; Moglia C; Buccinnà B; Grifoni S; Ramondetti C; Lomartire A; Rinaudo MT; Piccinini M; Giordana MT; Chiò A. | |
| In CD28-costimulated human naïve CD4(+) T cells, I-κB kinase controls the expression of cell cycle regulatory proteins via interleukin-2-independent mechanisms | 2010 | Lupino E; Buccinnà B; Ramondetti C; Lomartire A; De Marco G; Ricotti E; Tovo PA; Rinaudo MT; Piccinini M | |
| Deregulated Sphingolipid Metabolism and Membrane Organization in Neurodegenerative Disorders | 2010 | Piccinini Marco; Scandroglio Federica; Prioni Simona; Buccinnà Barbara; Loberto Nicoletta; Aureli Massimo; Chigorno Vanna; Lupino Elisa; Demarco Giovanni; Lomartire Annarosa; Rinaudo Maria Teresa; Sonnino Sandro; Prinetti Alessandro. | |
| TDP-43 Redistribution Is an Early Event in Sporadic Amyotrophic Lateral Sclerosis | 2010 | Giordana MT; Piccinini M; Grifoni S; De Marco G; Vercellino M; Magistrello M; Pellerino A; Buccinnà B; Lupino E; Rinaudo MT. | |
| N-CAM Dysfunction and Unexpected Accumulation of PSA-NCAM in Brain of Adult-Onset Autosomal-Dominant Leukodystrophy. | 2010 | Piccinini Marco; Buccinnà Barbara; De Marco Giovanni; Lupino Elisa; Ramondetti Cristina; Grifoni Silvia; Votta Barbara; Giordana Maria Teresa; Rinaudo Maria Teresa | |
| TDP-43 redistribution is an early event in sporadic amyotrophic lateral sclerosis | 2009 | Giordana MT; Piccinini M; Grifoni S; De Marco G; Vercellino M; Magistrello M; Pellerino A; Buccinnà B; Lupino E; Rinaudo M T | |
| The expression pattern of TAR DNA-binding protein 43 (TDP-43) in peripheral blood mononuclear cells (PBMC) in individuals affected by amyotrophific lateral sclerosis (ALS) and their healthy relatives | 2009 | De Marco G; Piccinini M; Lupino E; Lomartire A; Buccinnà B; Ramondetti C; Grifoni S; Giordana MT; Rinaudo MT | |
| An approach to the timing of altered localization of TDP-43 in ALS motor neurons during disease progression | 2009 | Giordana MT; Grifoni S; Piccinini M; Pellerino A; De Marco G ; Buccinnà B ; Lupino E ; Naldi A; Magistrello M; Rinaudo MT | |
| Dysfunctions in N_CAM and unexpected accumulation of PSA_NCAM in brain of Autosomal dominant adult onset leukodystrophy (ADLD) | 2009 | Buccinnà B; De Marco G; Piccinini M; Lupino E; Lomartire A; Ramondetti C; Grifoni S; Giordana MT; Rinaudo MT | |
| Alterations of myelin-specific proteins and sphingolipids characterize the brains of acid sphingomyelinase-deficient mice, an animal model of niemannpick disease type A | 2009 | Barbara Buccinnà; Marco Piccinini; Alessandro Prinetti; Federica Scandroglio; Simona Prioni; Manuela Valsecchi; Barbara Votta; Silvia Grifoni; Elisa Lupino; Cristina Ramondetti; Edward H. Schuchman; Maria Teresa Giordana; Sandro Sonnino; Maria Teresa Rinaudo | |
| Alterations of protein and lipid patterns in brain white matter of ASMKO mice, the animal model of Niemann-Pick disease type A | 2009 | Piccinini M; Buccinnà B; Prinetti A; Scandroglio F; Prioni S; Valsecchi M; Lupino E; Ramondetti C; Sonnino S; Rinaudo MT |
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