TRAPANI, ELIANA

TRAPANI, ELIANA  

SCIENZE CLINICHE E BIOLOGICHE  

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Altered redox homeostasis and signaling in Cerebral Cavernous Malformation disease: towards a complex but unifying pathogenic mechanism and therapeutic implications 2018 Trapani, Eliana; Antognelli, Cinzia; Goitre, Luca; Perrelli, Andrea; Sarri, Sara; Barrera, Giuseppina; Talesa, Vincenzo; Trabalzini, Lorenza; Retta, Saverio Francesco
Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies 2016 Marchi, Saverio; Trapani, Eliana; Corricelli, Mariangela; Goitre, Luca; Pinton, Paolo; Retta, Saverio Francesco
Cerebral cavernous malformation (CCM) disease: from monogenic forms to genetic susceptibility factors 2015 Trapani, E; Retta, S F
Cerebral Cavernous Malformations: from disease mechanisms to novel therapeutic approaches 2014 Goitre L.; Moglia A.; Trapani E.; Marchi S.; Pinton P.; Delle Monache S.; Cianfruglia L.; Armeni T.; Principato G.; Antognelli C.; Talesa V.; Tognon M.; Fontanella M.; Baldini E.; Trabalzini L.; Li D.Y.; Retta S.F.
Cerebral Cavernous Malformations: the CCM Italia research network offers new therapeutic perspectives 2013 Goitre L.; Cutano V.; Trapani E.; Morina A.; Canzoneri R.; Pergolizzi B.; Gianoglio S.; Moglia A.; Cianfruglia L.; Armeni T.; Delle Monache S.; Tognon M.; Fontanella M.; Baldini E.; Trabalzini L.; Retta S.F.
Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1 2016 Choquet, Hélène; Trapani, Eliana; Goitre, Luca; Trabalzini, Lorenza; Akers, Amy; Fontanella, Marco; Hart, Blaine L.; Morrison, Leslie A.; Pawlikowska, Ludmila; Kim, Helen; Retta, Saverio Francesco
Data in support of sustained upregulation of adaptive redox homeostasis mechanisms caused by KRIT1 loss-of-function 2018 Antognelli, Cinzia; Trapani, Eliana; Delle Monache, Simona; Perrelli, Andrea; Fornelli, Claudia; Retta, Francesca; Cassoni, Paola; Talesa, Vincenzo Nicola; Retta, Saverio Francesco*
Defective autophagy is a key feature of cerebral cavernous malformations 2015 Marchi, Saverio; Corricelli, Mariangela; Trapani, Eliana; Bravi, Luca; Pittaro, Alessandra; Delle Monache, Simona; Ferroni, Letizia; Patergnani, Simone; Missiroli, Sonia; Goitre, Luca; Trabalzini, Lorenza; Rimessi, Alessandro; Giorgi, Carlotta; Zavan, Barbara; Cassoni, Paola; Dejana, Elisabetta; Retta, Saverio Francesco; Pinton, Paolo
Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast 2015 Moglia, Andrea; Goitre, Luca; Gianoglio, Silvia; Baldini, Eva; Trapani, Eliana; Genre, Andrea; Scattina, Antonella; Dondo, Giancarlo; Trabalzini, Lorenza; Beekwilder, Jules; Retta, Saverio Francesco
Identification of risk factors and biomarkers of diagnostic and prognostic value associated with clinical progression and severity of cerebral cavernous malformations 2018 Fornelli, Claudia; Trapani, Eliana; Mastrocola, Raffaella; Perrelli, Andrea; Benedetti, Valerio; Zotta, Alessia; Costantino, Giulia; Geddo, Federica; Boda, Enrica; Biasi, Fiorella; Goitre, Luca; Retta, Saverio Francesco
KRIT1 loss of function causes a ROS-dependent upregulation of c-Jun 2014 L. Goitre; E. De Luca; S. Braggion; E. Trapani; M. Guglielmotto; F. Biasi; M. Forni; A. Moglia; L. Trabalzini; S.F. Retta
KRIT1 loss of function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease 2019 Trapani, E; Antognelli, C; Delle Monache, S; Perrelli, A; Fornelli, C; Benedetti, V; Sarri, S; Costantino, G; Geddo, F; Zotta, A; Goitre, L; Retta, SF
KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease 2018 Antognelli, Cinzia*; Trapani, Eliana; Delle Monache, Simona; Perrelli, Andrea; Daga, Martina; Pizzimenti, Stefania; Barrera, Giuseppina; Cassoni, Paola; Angelucci, Adriano; Trabalzini, Lorenza; Talesa, Vincenzo Nicola; Goitre, Luca; Retta, Saverio Francesco
KRIT1 loss-of-function induces a sustained Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease 2018 Perrelli, Andrea; Trapani, Eliana; Antognelli, Cinzia; Monache, Simona Delle; Fornelli, Claudia; Benedetti, Valerio; Costantino, Giulia; Geddo, Federica; Zotta, Alessia; Sarri, Sara; Bratti, Giovanna; Goitre, Luca; Retta, Saverio Francesco
Metabolic engineering of Saccharomyces cerevisiae for the production of avenanthramide analogous endowed with bioactive properties 2015 Moglia, A.; Trapani, E.; Yang, Z.; Di Scipio, F.; Goitre, L.; Trabalzini L., Baldini E.; Berta, G.N.; Retta, S.F.
Metabolic engineering of yeast for the production of plant avenanthramide analogous endowed with antioxidant and antiproliferative properties 2016 Moglia, A.; Trapani, E.; Di Scipio, F.; Finetti, F.; Yang, Z.; Schiavo, I.; Goitre, L.; Baldini, E.; Donnini, S.; Trabalzini, L.; Berta, G.N.; Retta, S.F.
NADPH oxidase regulates the expression of angiogenic growth factors in Cerebral Cavernous Malformation cellular models 2018 Schiavo, Irene; Ercoli, Jasmine; Finetti, Federica; Trapani, Eliana; Retta, Saverio Francesco; Trabalzini, Lorenza
Novel insights into the role of oxidative stress in CCM pathogenesis 2014 Goitre L.; Trapani E.; Choquet H.; Moglia A.; Marchi S.; Pinton P.; Delle Monache S.; Armeni T.; Antognelli C.; Fontanella M.; Baldini E.; Hart B.; Morrison L.; Gibson C.; Li D.Y.; Kim H.; Trabalzini L.; Retta S.F.
Oxidative stress and Cerebral Cavernous Malformations (CCM): from disease mechanisms toward prevention and treatment 2014 Trapani E.; Cutano V.; Gianoglio S.; Moglia A.; Baldini E.; Trabalzini L.; Marchi S.; Pinton P.; Retta S.F.; Goitre L.
The Ras Superfamily of Small GTPases: The Unlocked Secrets 2014 Goitre, Luca; Trapani, Eliana; Lorenza, Trabalzini; Retta, Saverio Francesco