GIRAUDO, ALESSANDRO

GIRAUDO, ALESSANDRO  

SCIENZA E TECNOLOGIA DEL FARMACO  

Mostra records
Risultati 1 - 16 di 16 (tempo di esecuzione: 0.052 secondi).
Titolo Data di pubblicazione Autore(i) File
4-Hydroxy-1,2,3-triazole moiety as bioisostere of the carboxylic acid function: a novel scaffold to probe the orthosteric γ-aminobutyric acid receptor binding site 2018 Giraudo, Alessandro; Krall, Jacob; Nielsen, Birgitte; Sørensen, Troels E.; Kongstad, Kenneth T.; Rolando, Barbara; Boschi, Donatella; Frølund, Bente; Lolli, Marco L.
DESIGN, SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF NOVEL GABAaR LIGANDS BEARING 4-HYDROXYTRIAZOLE MOIETY 2017 Giraudo, Alessandro
Design, synthesis, and biological evaluation of flufenamic acid derived bioisosteres as inhibitors of aldo-keto reductase 1C3 (AKR1C3) expressed in prostate cancer 2016 Lolli, Marco; Cena, Clara; Giraudo, Alessandro; Marini, Elisabetta; Pippione, Agnese; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Sadiq, Maria; Pors, Klaus; Boschi, Donatella; Braga, Rudolpho; Andrade, Carolina.
Development of new hydroxypyrazole-based inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) 2014 A.C. Pippione; A. Giraudo; I. Galleano; U.J. Nilsson; I. Fritzson; A.P. Sundin; S. Al-Karadaghi; D. Boschi; M.L. Lolli
Five-Membered N-Heterocyclic Scaffolds as Novel Amino Bioisosteres at γ-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters 2019 Giraudo A.; Krall J.; Bavo F.; Nielsen B.; Kongstad K.T.; Rolando B.; De Blasio R.; Gloriam D.E.; Loffler R.; Thiesen L.; Harpsoe K.; Frydenvang K.; Boschi D.; Wellendorph P.; Lolli M.L.; Jensen A.A.; Frolund B.
Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies 2019 Pippione, Agnese C; Sainas, Stefano; Goyal, Parveen; Fritzson, Ingela; Cassiano, Gustavo C; Giraudo, Alessandro; Giorgis, Marta; Tavella, Tatyana A; Bagnati, Renzo; Rolando, Barbara; Caing-Carlsson, Rhawnie; Costa, Fabio T M; Andrade, Carolina Horta; Al-Karadaghi, Salam; Boschi, Donatella; Friemann, Rosmarie; Lolli, Marco L
Hydroxytriazole derivatives as potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors discovered by bioisosteric scaffold hopping approach 2017 Pippione, Agnese C.; Giraudo, Alessandro; Bonanni, Davide; Carnovale, Irene M.; Marini, Elisabetta; Cena, Clara; Costale, Annalisa; Zonari, Daniele; Pors, Klaus; Sadiq, Maria; Boschi, Donatella; Oliaro-Bosso, Simonetta; Lolli, Marco L
NEW HYDROXYAZOLES INHIBITORS OF AKR1C3 OBTAINED FROM NSAIDS BY SCAFFOLD HOPPING APPROACH AGAINST CASTRATE RESISTANT PROSTATE CANCER 2016 Boschi, Donatella; Pippione, Agnese Chiara; Giraudo, Alessandro; Carnovale, Irene Maria; Zorniotti, Sonia; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Marini, Elisabetta; Pors, Klaus; Festuccia, Claudio; Monache, Simona Delle; Zaffaroni, Nadia; Braga, Rodolpho Campos; Lucio Lolli, Marco
NEW HYDROXYAZOLES INHIBITORS OF ALDO-KETO REDUCTASE 1C3 (AKR1C3) OBTAINED BY SCAFFOLD HOPPING FROM FLUFENAMIC ACID AND INDOMETHACIN FOR CASTRATE RESISTANT PROSTATE CANCER 2016 Boschi, Donatella; Pippione, Agnese Chiara; Giraudo, Alessandro; Carnovale, Irene Maria; Zorniotti, Sonia; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Marini, Elisabetta; Pors, Klaus; Festuccia, Claudio; Monache, Simona Delle; Zaffaroni, Nadia; Braga, Rodolpho Campos; Lucio, Marco; Lolli,
Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with hydroxypyrazole core: new scaffolds against malaria disease 2019 Pippione AC, Sainas S, Giraudo A, Bonanni D, Villella N, Bertea C, Friemann R, Al-Karadaghi S, Boschi D, Lolli ML.
Regioselective N‐Alkylation of Ethyl 4‐Benzyloxy‐1,2,3‐triazolecarboxylate: A Useful Tool for the Synthesis of Carboxylic Acid Bioisosteres 2019 Sainas, Stefano; Pippione, Agnese C.; Giraudo, Alessandro; Martina, Katia; Bosca, Federica; Rolando, Barbara; Barge, Alessandro; Ducime, Alex; Federico, Antonella; Grossert, Stuart J.; White, Robert L.; Boschi, Donatella; Lolli, Marco L.
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF NOVEL AMINO BIOISOSTERES FOR THE GABAa RECEPTOR 2016 Giraudo, Alessandro; Jensen, Anders A.; Nielsen, Birgitte; Boschi, Donatella; Krall, Jacob; Marco L. Lolli, ; Frølund, Bente
Targeting Castration Resistant Prostate Cancer (CRPC) by innovative AKR1C3 inhibitors based on the 3-hydroxybenzoisoxazole structure 2016 Carnovale, Irene Maria; Pippione, Agnese Chiara; Giraudo, Alessandro; Federico, Antonella; Zorniotti, Sonia; Simonetta Oliaro Bosso, ; Ferrante, Terenzio; Marini, Elisabetta; Pors, Klaus; Braga, Rodolpho Campos; Boschi, Donatella; Lucio Lolli, Marco
Targeting the human Dihydroorotate Dehydrogenase (hDHODH) by a Scaffold Hopping Bioisosteric approach using Hydroxylated Pentaatomic Heterocycles 2016 Sainas, Stefano; Pippione, Agnese Chiara; Carnovale, IRENE MARIA; Giraudo, Alessandro; Giorgis, Marta; Braga Rodolpho Campos, ; Andrade Carolina Horta, ; Piccinini, Marco; Lupino, Elisa; Guedes, Rita; AL KARADAGHI, Salam; Boschi, Donatella; Lolli, Marco Lucio
Targeting the human Dihydroorotate Dehydrogenase (hDHODH) by a Scaffold Hopping Bioisosteric approach using Hydroxylated Pentatomic Heterocycles 2016 Stefano Sainas, Agnese Chiara Pippione, Irene Maria Carnovale, Alessandro Giraudo, Marta Giorgis, Rodolpho B. Braga, Carolina H. Andrade, Noemi Villella, Marco Piccinini, Elisa Lupino, Rosmarie Friemann, Salam Al-Kadaraghi, Donatella Boschi, Marco L. Lolli
Targeting the human Dihydroorotate Dehydrogenase (hDHODH) by a Scaffold Hopping Bioisosteric approach using Hydroxylated Pentatomic Heterocycles 2016 Sainas Stefano; Pippione Agnese Chiara; Carnovale Irene Maria; Giraudo Alessandro; Giorgis Marta; de Campos Braga Rodolpho; Andrade Carolina H; Villella Noemi; Friemann Rosmarie; Piccinini Marco; Lupino Elisa; Al-karadaghi Salam; Boschi Donatella;Lolli Marco Lucio