| Nome |
# |
|
A reagentless sensor based on fatty acid amide hydrolase, file e27ce426-d13e-2581-e053-d805fe0acbaa
|
409
|
|
Characterization of a new Baeyer-Villiger monooxygenase and conversion to a solely N-or S-oxidizing enzyme by a single R292 mutation, file e27ce429-7313-2581-e053-d805fe0acbaa
|
405
|
|
Human flavin-containing monooxygenase 3: Structural mapping of gene polymorphisms and insights into molecular basis of drug binding, file e27ce429-f493-2581-e053-d805fe0acbaa
|
340
|
|
Identification of human flavin-containing monooxygenase 3 substrates by a colorimetric screening assay, file e27ce42b-4cfb-2581-e053-d805fe0acbaa
|
338
|
|
Chemical applications of Class B flavoprotein monooxygenases, file e27ce42b-6fe4-2581-e053-d805fe0acbaa
|
277
|
|
Layer-by-Layer Assembly of Supported Lipid Bilayer Poly-L-Lysine Multilayers, file e27ce429-731b-2581-e053-d805fe0acbaa
|
273
|
|
Binding of methimazole and NADP(H) to human FMO3: In vitro and in silico studies, file e27ce42d-549a-2581-e053-d805fe0acbaa
|
268
|
|
Effect of sildenafil on human aromatase activity: From in vitro structural analysis to catalysis and inhibition in cells, file e27ce429-e37c-2581-e053-d805fe0acbaa
|
266
|
|
Optimization of the bacterial cytochrome P450 BM3 system for the production of human drug metabolites, file e27ce426-e8d4-2581-e053-d805fe0acbaa
|
265
|
|
Subtle structural changes in the Asp251Gly/Gln307His P450 BM3 mutant responsible for new activity toward diclofenac, tolbutamide and ibuprofen, file e27ce428-aadc-2581-e053-d805fe0acbaa
|
261
|
|
Expression of different types of [FeFe]-hydrogenase genes in bacteria isolated from a population of a bio-hydrogen pilot-scale plant, file e27ce428-b237-2581-e053-d805fe0acbaa
|
257
|
|
Hydrogen production at high Faradaic efficiency by a bio-electrode based on TiO2 adsorption of a new [FeFe]-hydrogenase from Clostridium perfringens, file e27ce42d-cf3f-2581-e053-d805fe0acbaa
|
250
|
|
Uncoupled human flavin-containing monooxygenase 3 releases superoxide radical in addition to hydrogen peroxide, file e27ce42f-40f6-2581-e053-d805fe0acbaa
|
247
|
|
Bioelectrochemical profiling of two common polymorphic variants of human FMO3 in presence of graphene oxide, file e27ce42b-067a-2581-e053-d805fe0acbaa
|
244
|
|
Catalytically self-sufficient cytochromes P450 for green production of fine chemicals, file e27ce42d-df53-2581-e053-d805fe0acbaa
|
244
|
|
Evidence for an elevated aspartate pKa in the active site of human aromatase, file e27ce427-0abe-2581-e053-d805fe0acbaa
|
239
|
|
Electrochemistry of Canis familiaris cytochrome P450 2D15 with gold nanoparticles: An alternative to animal testing in drug discovery, file e27ce429-695f-2581-e053-d805fe0acbaa
|
234
|
|
Expression and role of CYP505A1 in pathogenicity of Fusarium oxysporum f. sp. lactucae, file e27ce42f-7cac-2581-e053-d805fe0acbaa
|
233
|
|
N- and S-oxygenation activity of truncated human flavin-containing monooxygenase 3 and its common polymorphic variants, file e27ce430-f4e5-2581-e053-d805fe0acbaa
|
226
|
|
Electron transfer and H2 evolution in hybrid systems based on [FeFe]-hydrogenase anchored on modified TiO2, file e27ce42a-865e-2581-e053-d805fe0acbaa
|
225
|
|
CYP116B5: a new class VII catalytically self-sufficient cytochrome P450 from Acinetobacter radioresistens that enables growth on alkanes, file e27ce427-0abf-2581-e053-d805fe0acbaa
|
217
|
|
Hydroxylation of non-substituted polycyclic aromatic hydrocarbons by cytochrome P450 BM3 engineered by directed evolution, file e27ce426-e3e6-2581-e053-d805fe0acbaa
|
214
|
|
A direct time-based ITC approach for substrate turnover measurements demonstrated on human FMO3, file e27ce42d-fb79-2581-e053-d805fe0acbaa
|
211
|
|
Human cytochrome P450 3A4 as a biocatalyst: Effects of the engineered linker in modulation of coupling efficiency in 3A4-BMR chimeras, file e27ce42b-839f-2581-e053-d805fe0acbaa
|
198
|
|
Chimeric cytochrome P450 3A4 used for in vitro prediction of food–drug interactions, file e27ce431-1efb-2581-e053-d805fe0acbaa
|
195
|
|
[FeFe]-hydrogenases as biocatalysts in bio-hydrogen production, file e27ce42d-cf43-2581-e053-d805fe0acbaa
|
192
|
|
Laser-written nanoporous silicon diffraction gratings for biosensors, file e27ce428-a57c-2581-e053-d805fe0acbaa
|
190
|
|
The effect of a C298D mutation in CaHydA [FeFe]-hydrogenase: Insights into the protein-metal cluster interaction by EPR and FTIR spectroscopic investigation, file e27ce427-b85d-2581-e053-d805fe0acbaa
|
185
|
|
Chimeric P450 Enzymes: activity of artificial redox fusions driven by different reductases for biotechnological applications, file e27ce428-a580-2581-e053-d805fe0acbaa
|
180
|
|
Biochemical features of dye-decolorizing peroxidases: Current impact on lignin degradation, file e27ce432-ebbd-2581-e053-d805fe0acbaa
|
180
|
|
Graphene oxide-mediated electrochemistry of glucose oxidase on glassy carbon electrodes, file e27ce42d-cebe-2581-e053-d805fe0acbaa
|
179
|
|
Electrochemical Detection of Human Cytochrome P450 2A6
Inhibition: A Step toward Reducing Dependence on Smoking, file e27ce426-f1b7-2581-e053-d805fe0acbaa
|
176
|
|
Biohydrogen and biomethane production sustained by untreated matrices and alternative application of compost waste, file e27ce429-f7be-2581-e053-d805fe0acbaa
|
169
|
|
Effect of human flavin-containing monooxygenase 3 polymorphism on the metabolism of aurora kinase inhibitors, file e27ce426-e620-2581-e053-d805fe0acbaa
|
166
|
|
Dynamics and flexibility of human aromatase probed by FTIR and time resolved fluorescence spectroscopy, file e27ce426-f556-2581-e053-d805fe0acbaa
|
163
|
|
Improvement of Biocatalysts for Industrial and Environmental Purposes by Saturation Mutagenesis, file e27ce426-fdee-2581-e053-d805fe0acbaa
|
151
|
|
Ligand stabilization and effect on unfolding by polymorphism in human flavin-containing monooxygenase 3, file e27ce430-ecd8-2581-e053-d805fe0acbaa
|
146
|
|
Human flavin-containing monooxygenase 1 and its long-sought hydroperoxyflavin intermediate, file e27ce432-f121-2581-e053-d805fe0acbaa
|
146
|
|
Atypical effect of temperature tuning on the insertion of the catalytic iron-sulfur center in a recombinant [FeFe]-hydrogenase, file e27ce42d-cda5-2581-e053-d805fe0acbaa
|
138
|
|
Oxygen Stability in the New [FeFe]-Hydrogenase from Clostridium beijerinckii SM10 (CbA5H), file e27ce42a-bfae-2581-e053-d805fe0acbaa
|
135
|
|
Site saturation mutagenesis demonstrates a central role for cysteine 298 as proton donor to the catalytic site in CaHydA [FeFe]-hydrogenase, file e27ce426-ec02-2581-e053-d805fe0acbaa
|
131
|
|
Identification of Mutant Asp251Gly/Gln307His of Cytochrome P450 BM3 for the Generation of Metabolites of Diclofenac, Ibuprofen And Tolbutamide, file e27ce426-d961-2581-e053-d805fe0acbaa
|
129
|
|
Escherichia coli overexpressing a Baeyer-Villiger monooxygenase from Acinetobacter radioresistens become resistant to Imipenem, file e27ce429-72b0-2581-e053-d805fe0acbaa
|
126
|
|
Flavin-Containing Monooxygenase 3 Polymorphic Variants Significantly Affect Clearance of Tamoxifen and Clomiphene, file e27ce42d-4f6a-2581-e053-d805fe0acbaa
|
126
|
|
Human aromatase: perspectives in biochemistry and biotechnology, file e27ce428-aadf-2581-e053-d805fe0acbaa
|
113
|
|
Drug-drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4, file e27ce426-d4b1-2581-e053-d805fe0acbaa
|
108
|
|
Impact of R264C and R264H polymorphisms in human aromatase function, file e27ce42a-0cd4-2581-e053-d805fe0acbaa
|
105
|
|
Enzymatically produced trimethylamine N-Oxide: Conserving it or eliminating it, file e27ce42f-89d4-2581-e053-d805fe0acbaa
|
103
|
|
WIDESPREAD PESTICIDES ACT ON ESTROGEN RECEPTORS, file 962da55d-c2c2-4d47-9bdb-360c5005dc43
|
100
|
|
Heme iron centers in cytochrome P450: structure and catalytic activity, file e27ce429-f306-2581-e053-d805fe0acbaa
|
98
|
|
The Cranberry Extract Oximacro(R) Exerts in vitro Virucidal Activity Against Influenza Virus by Interfering With Hemagglutinin, file e27ce42c-e07f-2581-e053-d805fe0acbaa
|
98
|
|
Immobilization of CYP3A4 enzyme onto SBA-15-like mesoporous silica and porous silicon matrices, file e27ce426-c028-2581-e053-d805fe0acbaa
|
97
|
|
Inactivation mechanism of N61S mutant of human FMO3 towards trimethylamine, file e27ce42c-ab60-2581-e053-d805fe0acbaa
|
92
|
|
Crystal structure of bacterial CYP116B5 heme domain: New insights on class VII P450s structural flexibility and peroxygenase activity, file e27ce430-1a63-2581-e053-d805fe0acbaa
|
90
|
|
Polymorphism on human aromatase affects protein dynamics and substrate binding: spectroscopic evidence, file e27ce431-ecb6-2581-e053-d805fe0acbaa
|
88
|
|
Catalytic properties of catechol 1,2-dioxygenase from Acinetobacter radioresistens S13 immobilized on nanosponges, file e27ce426-bbaf-2581-e053-d805fe0acbaa
|
82
|
|
Molecular and structural evolution of cytochrome p450 aromatase, file e27ce432-0ee6-2581-e053-d805fe0acbaa
|
82
|
|
Production of drug metabolites by human FMO3 in Escherichia coli, file e27ce42f-df00-2581-e053-d805fe0acbaa
|
81
|
|
Activation of RSK by phosphomimetic substitution in the activation loop is prevented by structural constraints, file e27ce42f-737b-2581-e053-d805fe0acbaa
|
78
|
|
Towards improved catalytic efficiency in engineered human cytochrome P450 3A4-BMR, file e27ce426-d0d4-2581-e053-d805fe0acbaa
|
76
|
|
In vitro drug metabolism by C-terminally truncated human flavin-containing monooxygenase 3, file e27ce426-d972-2581-e053-d805fe0acbaa
|
74
|
|
Fluorescent nucleobase analogs, a first step towards intrinsically emissive PNAs, file 7928efd6-9406-48bb-8354-38de80dd341d
|
70
|
|
Human cytomegalovirus US21 protein is a viroporin that modulates calcium homeostasis and protects cells against apoptosis, file e27ce42d-b2f9-2581-e053-d805fe0acbaa
|
69
|
|
A safety cap protects hydrogenase from oxygen attack, file e27ce431-ce33-2581-e053-d805fe0acbaa
|
68
|
|
Isolation and characterisation of a new [FeFe]-hydrogenase from Clostridium perfringens., file e27ce428-b3e0-2581-e053-d805fe0acbaa
|
62
|
|
Engineering Macaca fascicularis cytochrome P450 2C20 to reduce animal testing for new drugs, file e27ce426-d573-2581-e053-d805fe0acbaa
|
61
|
|
Direct spectroscopic evidence for binding of anastrozole to the iron heme of human aromatase. Peering into the mechanism of aromatase inhibition, file e27ce426-dbad-2581-e053-d805fe0acbaa
|
61
|
|
Alternative to animal testing for new drugs: structural, functional and electrochemical studies of monkey CYP2C20 and dog CYP2D15, file e27ce426-c8de-2581-e053-d805fe0acbaa
|
60
|
|
Engineering heme binding sites in monomeric rop, file e27ce426-aebe-2581-e053-d805fe0acbaa
|
59
|
|
A rapid screening for cytochromes P450 catalysis on new chemical entities: cytochrome P450 BM3 and 1,2,5-oxadiazole derivatives, file e27ce427-b6d0-2581-e053-d805fe0acbaa
|
59
|
|
A bacterial BVMO capable of turning over hFMO3 substrates, file e27ce426-d140-2581-e053-d805fe0acbaa
|
56
|
|
Composizioni comprendenti bloccanti dei canali del calcio per l’uso nel trattamento di infezioni virali, file e27ce42d-bf73-2581-e053-d805fe0acbaa
|
55
|
|
Molecular basis for endocrine disruption by pesticides targeting aromatase and estrogen receptor, file e27ce430-f470-2581-e053-d805fe0acbaa
|
55
|
|
Improving sustainable hydrogen production from green waste: [FeFe]-hydrogenases quantitative gene expression RT-qPCR analysis in presence of autochthonous consortia, file e27ce432-b148-2581-e053-d805fe0acbaa
|
50
|
|
From in silico to in vitro substrate characterisation of Macaca fascicularis P450 2C20, file e27ce426-d13f-2581-e053-d805fe0acbaa
|
48
|
|
Effector role of cytochrome P450 reductase for androstenedione binding to human aromatase, file e27ce431-56fb-2581-e053-d805fe0acbaa
|
47
|
|
Bioelectrochemistry as a tool for the study of aromatization of steroids by human aromatase, file e27ce428-aadb-2581-e053-d805fe0acbaa
|
44
|
|
Multi-Enzymatic Cascade Reactions for the Synthesis of cis,cis-Muconic Acid, file e27ce434-46ff-2581-e053-d805fe0acbaa
|
43
|
|
EPR characterization of the heme domain of a self-sufficient cytochrome P450 (CYP116B5), file e27ce435-47e0-2581-e053-d805fe0acbaa
|
43
|
|
Fluorescence detection of ligand binding to labeled cytochrome P450 BM3, file e27ce426-d0d0-2581-e053-d805fe0acbaa
|
42
|
|
Studies of Cysteine 298 Role in [FeFe]-hydrogenases, file e27ce427-0c91-2581-e053-d805fe0acbaa
|
42
|
|
C-terminal truncation of hFMO3: combining molecular modelling with protein engineering, file e27ce426-d0d6-2581-e053-d805fe0acbaa
|
40
|
|
Understanding uncoupling in the multi-redox centre P450 3A4-BMR model system, file e27ce426-c8db-2581-e053-d805fe0acbaa
|
39
|
|
Human flavin-containing monooxygenase 3 on graphene oxide for drug metabolism screening, file e27ce428-aa9a-2581-e053-d805fe0acbaa
|
39
|
|
catalysis of immobilised human flavin-containing monooxygenase, file e27ce426-c8df-2581-e053-d805fe0acbaa
|
37
|
|
A new class IV cytochrome P450 enzyme: An evolutionary tale and an in silico analysis, file e27ce426-d0d5-2581-e053-d805fe0acbaa
|
37
|
|
A novel bacterial flavoenzyme (BVMO) for biotechnological applications, file e27ce426-c8eb-2581-e053-d805fe0acbaa
|
36
|
|
Detection of ligand binding to cytochrome P450 BMP labeled with a fluorophore, file e27ce426-be5c-2581-e053-d805fe0acbaa
|
35
|
|
Green production of indigo and indirubin by an engineered Baeyer–Villiger monooxygenase, file 26e55647-69cc-430c-b0e8-43261c45f364
|
33
|
|
Bioectrochemistry of drug metabolising human flavin containing monooxygenase, file e27ce426-b4a1-2581-e053-d805fe0acbaa
|
32
|
|
Isolation of strains from a bio-hydrogen plant: Novel [FeFe]-hydrogenases for Exploitation in Biotechnology, file e27ce427-0c93-2581-e053-d805fe0acbaa
|
32
|
|
Molecular Lego of Human Cytochrome P450: The Key Role of Heme Domain Flexibility for the Activity of the Chimeric Proteins, file e27ce435-2ace-2581-e053-d805fe0acbaa
|
32
|
|
Protein engineering and electrode modification for the creation of a P450 based biosensor, file e27ce426-c4b0-2581-e053-d805fe0acbaa
|
29
|
|
Molecular modelling of human flavin-containing monooxygenase 3, file e27ce426-c8e9-2581-e053-d805fe0acbaa
|
29
|
|
A biotechnological approach for the development of an enzyme-based platform with applications in the field of personalized medicine, file e27ce426-e030-2581-e053-d805fe0acbaa
|
29
|
|
Peroxide-driven catalysis of the heme domain of A. radioresistens cytochrome P450 116B5 for sustainable aromatic rings oxidation and drug metabolites production, file e27ce42f-535a-2581-e053-d805fe0acbaa
|
29
|
|
Drug-drug interactions of Cytochrome P450 3A4 studied by electrochemistry, file e27ce426-b4a2-2581-e053-d805fe0acbaa
|
28
|
|
Structural Basis for the Functional Roles of Critical Residues in Human Cytochrome P450 Aromatase, file e27ce428-aae3-2581-e053-d805fe0acbaa
|
26
|
|
Drug-drug and drug-food interactions of immobilised cytochrome P4503A4, file e27ce426-bfb6-2581-e053-d805fe0acbaa
|
25
|
|
Identification of endocrine disrupting chemicals acting on human aromatase, file e27ce432-b3dc-2581-e053-d805fe0acbaa
|
25
|
| Totale |
12.815 |