APPRATO, GIULIA
APPRATO, GIULIA
BIOTECNOLOGIE MOLECOLARI E SCIENZE PER LA SALUTE
Antioxidant and Anti-Inflammatory Activity of Combined Phycocyanin and Palmitoylethanolamide in Human Lung and Prostate Epithelial Cells
2022-01-01 Bergandi, Loredana; Apprato, Giulia; Silvagno, Francesca
Chamelogk: A Chromatographic Chameleonicity Quantifier to Design Orally Bioavailable Beyond-Rule-of-5 Drugs
2023-01-01 GARCÍA JIMÉNEZ DIEGO; Vallaro Maura; Rossi Sebastiano Matteo; Apprato Giulia; D'Agostini Giulia; Rossetti Paolo; Ermondi Giuseppe; Caron Giulia
DegraderTCM: A Computationally Sparing Approach for Predicting Ternary Degradation Complexes
2024-01-01 Rossetti P.; Apprato G.; Caron G.; Ermondi G.; Rossi Sebastiano M.
Exploring the chemical space of orally bioavailable PROTACs
2024-01-01 Apprato G.; Poongavanam V.; Garcia Jimenez D.; Atilaw Y.; Erdelyi M.; Ermondi G.; Caron G.; Kihlberg J.
Finding a needle in the haystack: ADME and pharmacokinetics/pharmacodynamics characterization and optimization toward orally available bifunctional protein degraders
2025-01-01 Apprato, Giulia; Caron, Giulia; Deshmukh, Gauri; Garcia-Jimenez, Diego; Haid, Robin Thomas Ulrich; Pike, Andy; Reichel, Andreas; Rynn, Caroline; Donglu, Zhang; Wittwer, Matthias Beat
Implementation of a strategic platform for the design of orally bioavailable PROTAC drugs
2025-07-15
In Silico Tools to Extract the Drug Design Information Content of Degradation Data: The Case of PROTACs Targeting the Androgen Receptor
2023-01-01 Apprato Giulia; D’Agostini Giulia; Rossetti Paolo; Ermondi Giuseppe; Caron Giulia
Molecular properties, including chameleonicity, as essential tools for designing the next generation of oral beyond rule of five drugs
2024-01-01 GARCÍA JIMÉNEZ D.; Vallaro M.; Vitagliano L.; Lopez L.L.; Apprato G.; Ermondi G.; Caron G.
Natural Epigenetic Modulators of Vitamin D Receptor
2020-01-01 Apprato, Giulia; Fiz, Camilla; Fusano, Isabella; Bergandi, Loredana; Silvagno, Francesca
Tgf beta induces vitamin d receptor and modulates mitochondrial activity of human pancreatic cancer cells
2021-01-01 Fiz C.; Apprato G.; Ricca C.; Aillon A.; Bergandi L.; Silvagno F.
The Quest for Oral PROTAC drugs: Evaluating the Weaknesses of the Screening Pipeline
2023-01-01 Apprato, Giulia; Ermondi, Giuseppe; Caron, Giulia
The Role of Vitamin D in Supporting Health in the COVID-19 Era
2022-01-01 Albergamo A.; Apprato G.; Silvagno F.
Vitamin d and beta-glucans synergically stimulate human macrophage activity
2021-01-01 Bergandi L.; Apprato G.; Silvagno F.