| Nome |
# |
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Characterization of a new Baeyer-Villiger monooxygenase and conversion to a solely N-or S-oxidizing enzyme by a single R292 mutation, file e27ce429-7313-2581-e053-d805fe0acbaa
|
406
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A reagentless sensor based on fatty acid amide hydrolase, file e27ce426-d13e-2581-e053-d805fe0acbaa
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405
|
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Identification of human flavin-containing monooxygenase 3 substrates by a colorimetric screening assay, file e27ce42b-4cfb-2581-e053-d805fe0acbaa
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343
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|
Human flavin-containing monooxygenase 3: Structural mapping of gene polymorphisms and insights into molecular basis of drug binding, file e27ce429-f493-2581-e053-d805fe0acbaa
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342
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Chemical applications of Class B flavoprotein monooxygenases, file e27ce42b-6fe4-2581-e053-d805fe0acbaa
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278
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Binding of methimazole and NADP(H) to human FMO3: In vitro and in silico studies, file e27ce42d-549a-2581-e053-d805fe0acbaa
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269
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Subtle structural changes in the Asp251Gly/Gln307His P450 BM3 mutant responsible for new activity toward diclofenac, tolbutamide and ibuprofen, file e27ce428-aadc-2581-e053-d805fe0acbaa
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265
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Layer-by-Layer Assembly of Supported Lipid Bilayer Poly-L-Lysine Multilayers, file e27ce429-731b-2581-e053-d805fe0acbaa
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265
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Hydrogen production at high Faradaic efficiency by a bio-electrode based on TiO2 adsorption of a new [FeFe]-hydrogenase from Clostridium perfringens, file e27ce42d-cf3f-2581-e053-d805fe0acbaa
|
250
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Uncoupled human flavin-containing monooxygenase 3 releases superoxide radical in addition to hydrogen peroxide, file e27ce42f-40f6-2581-e053-d805fe0acbaa
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247
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Bioelectrochemical profiling of two common polymorphic variants of human FMO3 in presence of graphene oxide, file e27ce42b-067a-2581-e053-d805fe0acbaa
|
246
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Electrochemistry of Canis familiaris cytochrome P450 2D15 with gold nanoparticles: An alternative to animal testing in drug discovery, file e27ce429-695f-2581-e053-d805fe0acbaa
|
235
|
|
Expression and role of CYP505A1 in pathogenicity of Fusarium oxysporum f. sp. lactucae, file e27ce42f-7cac-2581-e053-d805fe0acbaa
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235
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N- and S-oxygenation activity of truncated human flavin-containing monooxygenase 3 and its common polymorphic variants, file e27ce430-f4e5-2581-e053-d805fe0acbaa
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228
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CYP116B5: a new class VII catalytically self-sufficient cytochrome P450 from Acinetobacter radioresistens that enables growth on alkanes, file e27ce427-0abf-2581-e053-d805fe0acbaa
|
219
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A direct time-based ITC approach for substrate turnover measurements demonstrated on human FMO3, file e27ce42d-fb79-2581-e053-d805fe0acbaa
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213
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Chimeric cytochrome P450 3A4 used for in vitro prediction of food–drug interactions, file e27ce431-1efb-2581-e053-d805fe0acbaa
|
198
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Laser-written nanoporous silicon diffraction gratings for biosensors, file e27ce428-a57c-2581-e053-d805fe0acbaa
|
189
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Human cytochrome P450 3A4 as a biocatalyst: Effects of the engineered linker in modulation of coupling efficiency in 3A4-BMR chimeras, file e27ce42b-839f-2581-e053-d805fe0acbaa
|
182
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Biochemical features of dye-decolorizing peroxidases: Current impact on lignin degradation, file e27ce432-ebbd-2581-e053-d805fe0acbaa
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180
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Graphene oxide-mediated electrochemistry of glucose oxidase on glassy carbon electrodes, file e27ce42d-cebe-2581-e053-d805fe0acbaa
|
179
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Electrochemical Detection of Human Cytochrome P450 2A6
Inhibition: A Step toward Reducing Dependence on Smoking, file e27ce426-f1b7-2581-e053-d805fe0acbaa
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177
|
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Effect of human flavin-containing monooxygenase 3 polymorphism on the metabolism of aurora kinase inhibitors, file e27ce426-e620-2581-e053-d805fe0acbaa
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166
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Chimeric P450 Enzymes: activity of artificial redox fusions driven by different reductases for biotechnological applications, file e27ce428-a580-2581-e053-d805fe0acbaa
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166
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Dynamics and flexibility of human aromatase probed by FTIR and time resolved fluorescence spectroscopy, file e27ce426-f556-2581-e053-d805fe0acbaa
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160
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Ligand stabilization and effect on unfolding by polymorphism in human flavin-containing monooxygenase 3, file e27ce430-ecd8-2581-e053-d805fe0acbaa
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147
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Human flavin-containing monooxygenase 1 and its long-sought hydroperoxyflavin intermediate, file e27ce432-f121-2581-e053-d805fe0acbaa
|
146
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Flavin-Containing Monooxygenase 3 Polymorphic Variants Significantly Affect Clearance of Tamoxifen and Clomiphene, file e27ce42d-4f6a-2581-e053-d805fe0acbaa
|
127
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Escherichia coli overexpressing a Baeyer-Villiger monooxygenase from Acinetobacter radioresistens become resistant to Imipenem, file e27ce429-72b0-2581-e053-d805fe0acbaa
|
126
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Drug-drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4, file e27ce426-d4b1-2581-e053-d805fe0acbaa
|
108
|
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Enzymatically produced trimethylamine N-Oxide: Conserving it or eliminating it, file e27ce42f-89d4-2581-e053-d805fe0acbaa
|
101
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Immobilization of CYP3A4 enzyme onto SBA-15-like mesoporous silica and porous silicon matrices, file e27ce426-c028-2581-e053-d805fe0acbaa
|
92
|
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Inactivation mechanism of N61S mutant of human FMO3 towards trimethylamine, file e27ce42c-ab60-2581-e053-d805fe0acbaa
|
86
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|
Production of drug metabolites by human FMO3 in Escherichia coli, file e27ce42f-df00-2581-e053-d805fe0acbaa
|
77
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In vitro drug metabolism by C-terminally truncated human flavin-containing monooxygenase 3, file e27ce426-d972-2581-e053-d805fe0acbaa
|
74
|
|
Towards improved catalytic efficiency in engineered human cytochrome P450 3A4-BMR, file e27ce426-d0d4-2581-e053-d805fe0acbaa
|
71
|
|
Engineering Macaca fascicularis cytochrome P450 2C20 to reduce animal testing for new drugs, file e27ce426-d573-2581-e053-d805fe0acbaa
|
63
|
|
A rapid screening for cytochromes P450 catalysis on new chemical entities: cytochrome P450 BM3 and 1,2,5-oxadiazole derivatives, file e27ce427-b6d0-2581-e053-d805fe0acbaa
|
59
|
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Engineering heme binding sites in monomeric rop, file e27ce426-aebe-2581-e053-d805fe0acbaa
|
58
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Alternative to animal testing for new drugs: structural, functional and electrochemical studies of monkey CYP2C20 and dog CYP2D15, file e27ce426-c8de-2581-e053-d805fe0acbaa
|
55
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A bacterial BVMO capable of turning over hFMO3 substrates, file e27ce426-d140-2581-e053-d805fe0acbaa
|
53
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From in silico to in vitro substrate characterisation of Macaca fascicularis P450 2C20, file e27ce426-d13f-2581-e053-d805fe0acbaa
|
44
|
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Bioelectrochemistry as a tool for the study of aromatization of steroids by human aromatase, file e27ce428-aadb-2581-e053-d805fe0acbaa
|
44
|
|
Human flavin-containing monooxygenase 3 on graphene oxide for drug metabolism screening, file e27ce428-aa9a-2581-e053-d805fe0acbaa
|
43
|
|
Fluorescence detection of ligand binding to labeled cytochrome P450 BM3, file e27ce426-d0d0-2581-e053-d805fe0acbaa
|
42
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Understanding uncoupling in the multi-redox centre P450 3A4-BMR model system, file e27ce426-c8db-2581-e053-d805fe0acbaa
|
40
|
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C-terminal truncation of hFMO3: combining molecular modelling with protein engineering, file e27ce426-d0d6-2581-e053-d805fe0acbaa
|
38
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Detection of ligand binding to cytochrome P450 BMP labeled with a fluorophore, file e27ce426-be5c-2581-e053-d805fe0acbaa
|
36
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catalysis of immobilised human flavin-containing monooxygenase, file e27ce426-c8df-2581-e053-d805fe0acbaa
|
34
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|
A novel bacterial flavoenzyme (BVMO) for biotechnological applications, file e27ce426-c8eb-2581-e053-d805fe0acbaa
|
34
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A new class IV cytochrome P450 enzyme: An evolutionary tale and an in silico analysis, file e27ce426-d0d5-2581-e053-d805fe0acbaa
|
33
|
|
Isolation of strains from a bio-hydrogen plant: Novel [FeFe]-hydrogenases for Exploitation in Biotechnology, file e27ce427-0c93-2581-e053-d805fe0acbaa
|
32
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Bioectrochemistry of drug metabolising human flavin containing monooxygenase, file e27ce426-b4a1-2581-e053-d805fe0acbaa
|
31
|
|
Peroxide-driven catalysis of the heme domain of A. radioresistens cytochrome P450 116B5 for sustainable aromatic rings oxidation and drug metabolites production, file e27ce42f-535a-2581-e053-d805fe0acbaa
|
28
|
|
A biotechnological approach for the development of an enzyme-based platform with applications in the field of personalized medicine, file e27ce426-e030-2581-e053-d805fe0acbaa
|
27
|
|
Drug-drug and drug-food interactions of immobilised cytochrome P4503A4, file e27ce426-bfb6-2581-e053-d805fe0acbaa
|
26
|
|
Molecular modelling of human flavin-containing monooxygenase 3, file e27ce426-c8e9-2581-e053-d805fe0acbaa
|
26
|
|
Protein engineering and electrode modification for the creation of a P450 based biosensor, file e27ce426-c4b0-2581-e053-d805fe0acbaa
|
25
|
|
Drug-drug interactions of Cytochrome P450 3A4 studied by electrochemistry, file e27ce426-b4a2-2581-e053-d805fe0acbaa
|
24
|
|
Influence of inter-domain dynamics and surrounding environment flexibility on the direct electrochemistry and electrocatalysis of self-sufficient cytochrome P450 3A4-BMR chimeras, file e27ce42d-c12f-2581-e053-d805fe0acbaa
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23
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Drug-drug interactions of human cytochrome P450s by a new electrochemical array, file e27ce426-c029-2581-e053-d805fe0acbaa
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22
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|
Drug-drug and drug-food interactions of cytochrome P4503A4, file e27ce426-c4b2-2581-e053-d805fe0acbaa
|
22
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|
A new electrochemical platform based on P450 2C8 for drug discovery, file e27ce426-c8e8-2581-e053-d805fe0acbaa
|
22
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|
Molecular modelling and protein engineering of a C-terminally truncated human flavin-containing monooxygenase 3, file e27ce426-d0d2-2581-e053-d805fe0acbaa
|
22
|
|
Drug-drug and food-drug interactions of cytochrome P4503A4, file e27ce426-c4b3-2581-e053-d805fe0acbaa
|
16
|
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Green production of indigo and indirubin by an engineered Baeyer–Villiger monooxygenase, file 26e55647-69cc-430c-b0e8-43261c45f364
|
10
|
|
Bioelectrochemical platform with human monooxygenases: FMO1 and CYP3A4 tandem reactions with phorate, file d813a596-7675-4eca-8c31-54f785c3fea5
|
10
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P450-based porous silicon biosensor for arachidonic acid detection, file e27ce426-d0d1-2581-e053-d805fe0acbaa
|
3
|
|
Direct electrochemistry of an [FeFe]-hydrogenase on a TiO(2) Electrode., file e27ce426-da98-2581-e053-d805fe0acbaa
|
3
|
|
Breakthrough in P450 bioelectrochemistry and future perspectives, file e27ce426-c8d9-2581-e053-d805fe0acbaa
|
2
|
|
Molecular modelling and protein engineering of a C-terminally truncated human flavin-containing monooxygenase 3, file e27ce426-d141-2581-e053-d805fe0acbaa
|
2
|
|
Iron-based redox centres of reductase and oxygenase components of phenol hydroxylase from A. radioresistens: A redox chain working at highly positive redox potentials, file e27ce426-db2d-2581-e053-d805fe0acbaa
|
2
|
|
Influence of inter-domain dynamics and surrounding environment flexibility on the direct electrochemistry and electrocatalysis of self-sufficient cytochrome P450 3A4-BMR chimeras, file e27ce42d-a7e0-2581-e053-d805fe0acbaa
|
2
|
|
Protein and electrode engineering for the covalent immobilization of P450 BMP on gold, file e27ce426-b1e4-2581-e053-d805fe0acbaa
|
1
|
|
Effect of pH on the conformation and activity of human aromatase, file e27ce426-c8e7-2581-e053-d805fe0acbaa
|
1
|
|
Fluorescence detection of ligand binding to labeled cytochrome P450 BM3, file e27ce426-d0cf-2581-e053-d805fe0acbaa
|
1
|
|
Purification of a stable form of human aromatase in the absence of substrate: Effect of neuronal physiological pH changes on its substrate binding and activity, file e27ce426-da13-2581-e053-d805fe0acbaa
|
1
|
|
Entrapment of human flavin-containing monooxygenase 3 in the presence of gold nanoparticles: TEM, FTIR and electrocatalysis, file e27ce426-ec44-2581-e053-d805fe0acbaa
|
1
|
|
Electrochemical Detection of Human Cytochrome P450 2A6
Inhibition: A Step toward Reducing Dependence on Smoking, file e27ce426-f1b8-2581-e053-d805fe0acbaa
|
1
|
|
Human flavin-containing monooxygenase 3 on graphene oxide for drug metabolism screening, file e27ce427-9e9b-2581-e053-d805fe0acbaa
|
1
|
|
A rapid screening for cytochromes P450 catalysis on new chemical entities: cytochrome P450 BM3 and 1,2,5-oxadiazole derivatives, file e27ce427-c541-2581-e053-d805fe0acbaa
|
1
|
|
Modulation of the interaction between human P450 3A4 and B. megaterium reductase via engineered loops, file e27ce42c-212e-2581-e053-d805fe0acbaa
|
1
|
|
Peroxide-driven catalysis of the heme domain of A. radioresistens cytochrome P450 116B5 for sustainable aromatic rings oxidation and drug metabolites production, file e27ce42f-55f8-2581-e053-d805fe0acbaa
|
1
|
|
Engineered human CYP2C9 and its main polymorphic variants for bioelectrochemical measurements of catalytic response, file e27ce431-0b36-2581-e053-d805fe0acbaa
|
1
|
|
Hydrogen production at high Faradaic efficiency by a bio-electrode based on TiO2 adsorption of a new [FeFe]-hydrogenase from Clostridium perfringens, file e27ce432-5a2f-2581-e053-d805fe0acbaa
|
1
|
| Totale |
8266 |