| Nome |
# |
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BROAD SPECTRUM METALLO beta-LACTAMASES INHIBITORS: NEW TOOLS AGAINST CLINICALLY-RELEVANT CARBAPENEMASES, file a2376517-db0e-47da-b7e5-1c34ca81ce66
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483
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Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells, file e27ce426-dd5b-2581-e053-d805fe0acbaa
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446
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Multitarget Drugs: Focus on the NO-donor hybrid drugs, file e27ce426-b4e8-2581-e053-d805fe0acbaa
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329
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Synthesis and preliminary pharmacological characterisation of a new class of nitrogen-containing bisphosphonates (N-BPs), file e27ce426-be80-2581-e053-d805fe0acbaa
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306
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Synthesis and preliminary biological profile of new NO-donor tolbutamide analogues., file e27ce426-d5c3-2581-e053-d805fe0acbaa
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260
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Synthesis physicochemical profile and PAMPA study of new NO-donor edaravone co-drugs, file e27ce426-d83a-2581-e053-d805fe0acbaa
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253
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Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance., file e27ce426-e3dd-2581-e053-d805fe0acbaa
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252
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New nitric oxide or hydrogen sulfide releasing aspirins, file e27ce426-d99c-2581-e053-d805fe0acbaa
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245
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Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity, file e27ce42c-26e7-2581-e053-d805fe0acbaa
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244
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NO-Donor Phenols: A New Class of Products Endowed with Antioxidant and Vasodilator Properties, file e27ce426-aadd-2581-e053-d805fe0acbaa
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228
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Nitrooxymethyl Substituted Analogues of Celecoxib: Synthesis and Pharmacological Characterization, file e27ce426-b8e0-2581-e053-d805fe0acbaa
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224
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|
Searching for new NO-donor aspirin-like molecules: furoxanylacyl derivatives of salicylic acid and related furazans, file e27ce426-dd5a-2581-e053-d805fe0acbaa
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202
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Water-Soluble Nitric-Oxide-Releasing Acetylsalicylic Acid
(ASA) Prodrugs, file e27ce426-f7b4-2581-e053-d805fe0acbaa
|
197
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A molecular hybrid producing simultaneously singlet oxygen and nitric oxide by single photon excitation with green light, file e27ce42d-b04b-2581-e053-d805fe0acbaa
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195
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Novel Antioxidant Agents Deriving From Molecular Combination of Vitamin C and NO-donor moieties, file e27ce426-aaa3-2581-e053-d805fe0acbaa
|
179
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NO-donor COX-2 inhibitors. New nitrooxy-substituted 1,5-diarylimidazoles endowed with COX-2 inhibitory and vasodilator properties, file e27ce426-ae93-2581-e053-d805fe0acbaa
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172
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A Nitric Oxide-Donor Furoxan Moiety Improves the Efficacy of Edaravone against Early Renal Dysfunction and Injury Evoked by Ischemia/Reperfusion, file e27ce427-0dd8-2581-e053-d805fe0acbaa
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158
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Mechanistic insights into cyclooxygenase irreversible inactivation byaspirin, file e27ce426-b277-2581-e053-d805fe0acbaa
|
144
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|
Doxorubicin-antioxidant multitarget drugs, file e27ce426-f93b-2581-e053-d805fe0acbaa
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144
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Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance., file e27ce426-e3df-2581-e053-d805fe0acbaa
|
138
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Synthesis and biological evaluation of the first example of NO-donor
histone deacetylase inhibitor, file e27ce426-f223-2581-e053-d805fe0acbaa
|
134
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Structural and biological characterization of new hybrid drugs joining an HDAC inhibitor to different NO-donors, file e27ce42c-8704-2581-e053-d805fe0acbaa
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126
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Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution, file e27ce42d-a53b-2581-e053-d805fe0acbaa
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117
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NO-donor COX-2 inhibitors. New nitrooxy-substituted 1,5-diarylimidazoles endowed with COX-2 inhibitory and vasodilator properties, file e27ce426-ae92-2581-e053-d805fe0acbaa
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111
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Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis, file e27ce429-b98b-2581-e053-d805fe0acbaa
|
108
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Combination of PDT and NOPDT with a tailored BODIPY derivative, file e27ce42e-df95-2581-e053-d805fe0acbaa
|
102
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Anti-pseudomonas activity of 3-nitro-4-phenylfuroxan, file e27ce42d-8dfe-2581-e053-d805fe0acbaa
|
97
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|
H2S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance, file e27ce428-be10-2581-e053-d805fe0acbaa
|
92
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(Nitrooxyacyloxy)methyl esters of aspirin as novel nitric oxide releasing aspirins, file e27ce426-b275-2581-e053-d805fe0acbaa
|
89
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|
Mitochondrial delivery of phenol substructure triggers mitochondrial depolarization and apoptosis of cancer cells, file e27ce42c-f044-2581-e053-d805fe0acbaa
|
86
|
|
New nitric oxide or hydrogen sulfide releasing aspirins, file e27ce426-d99d-2581-e053-d805fe0acbaa
|
72
|
|
Searching for new NO-donor Aspirin-like molecules: a new class of nitrooxy-acyl derivatives of salicylic acid, file e27ce426-bbb7-2581-e053-d805fe0acbaa
|
71
|
|
Doxorubicin-antioxidant multitarget drugs, file e27ce426-f93a-2581-e053-d805fe0acbaa
|
70
|
|
Effects of Nitric Oxide Donor Antioxidants Containing the Phenol Vitamin E Substructure and a Furoxan Moiety on Ischemia/Riperfusion Injury, file e27ce426-bc73-2581-e053-d805fe0acbaa
|
66
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Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants, file e27ce426-b11b-2581-e053-d805fe0acbaa
|
60
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|
Nitrooxymethyl Substituted Analogues of Celecoxib: Synthesis and Pharmacological Characterization, file e27ce426-b8e1-2581-e053-d805fe0acbaa
|
60
|
|
H2S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance, file e27ce428-bf82-2581-e053-d805fe0acbaa
|
60
|
|
A rapid screening for cytochromes P450 catalysis on new chemical entities: cytochrome P450 BM3 and 1,2,5-oxadiazole derivatives, file e27ce427-b6d0-2581-e053-d805fe0acbaa
|
59
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A Nonmetal-Containing Nitric Oxide Donor Activated with Single-Photon Green Light, file e27ce42c-1578-2581-e053-d805fe0acbaa
|
59
|
|
NO-Donor Melatonin Derivatives: Synthesis And In Vitro Pharmacological Characterization, file e27ce426-bbd1-2581-e053-d805fe0acbaa
|
56
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Quinone based nitric oxide donating compounds, file e27ce427-a390-2581-e053-d805fe0acbaa
|
56
|
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Tuning the Hydrophobicity of a Mitochondria-Targeted NO Photodonor, file e27ce42c-bcef-2581-e053-d805fe0acbaa
|
54
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Can we exploit β-lactamases intrinsic dynamics for designing more effective inhibitors?, file e27ce431-4a0d-2581-e053-d805fe0acbaa
|
53
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Furazan and furoxan sulfonamides are strong α-carbonic anhydrase inhibitors and potential antiglaucoma agents, file e27ce426-ef96-2581-e053-d805fe0acbaa
|
52
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Designing Multitarget Anti-inflammatory Agents: Chemical Modulation of the Lumiracoxib Structure toward Dual Thromboxane Antagonists-COX-2 Inhibitors., file e27ce427-b2ad-2581-e053-d805fe0acbaa
|
51
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|
Synthesis of Some Novel Organic Nitrates and Comparative in Vitro Study of Their Vasodilator Profile, file e27ce426-baef-2581-e053-d805fe0acbaa
|
50
|
|
Nitric Oxide Donor Doxorubicins Accumulate into Doxorubicin-Resistant Human Colon Cancer Cells Inducing Cytotoxicity, file e27ce426-c49d-2581-e053-d805fe0acbaa
|
50
|
|
Galactosylated Pro-Drug of Ursodeoxycholic Acid: Design, Synthesis, Characterization, and Pharmacological Effects in a Rat Model of Estrogen-Induced Cholestasis, file e27ce42f-1217-2581-e053-d805fe0acbaa
|
43
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Light-Tunable Generation of Singlet Oxygen and Nitric Oxide with a Bichromophoric Molecular Hybrid: a Bimodal Approach to Killing Cancer Cells, file e27ce429-141a-2581-e053-d805fe0acbaa
|
38
|
|
Multitarget antioxidant NO-donor organic nitrates: a novel ap-proach to overcome nitrates tolerance, an ex vivo study, file e27ce434-a776-2581-e053-d805fe0acbaa
|
37
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New furoxan derivatives for the treatment of ocular hypertension, file e27ce42b-615d-2581-e053-d805fe0acbaa
|
35
|
|
Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells, file e27ce433-4651-2581-e053-d805fe0acbaa
|
35
|
|
Novel nitro-oxy derivatives of celecoxib for the regulation of colon cancer cell growth, file e27ce426-b444-2581-e053-d805fe0acbaa
|
33
|
|
A Potent and Selective P-gp Modulator for Altering Multidrug Resistance Due to Pump Overexpression, file e27ce42a-1088-2581-e053-d805fe0acbaa
|
31
|
|
New furoxan derivatives for the treatment of ocular hypertension, file e27ce42b-15a7-2581-e053-d805fe0acbaa
|
31
|
|
Paracetamol-Galactose Conjugate: A Novel Prodrug for an Old Analgesic Drug, file e27ce435-98a8-2581-e053-d805fe0acbaa
|
29
|
|
Structure-Activity Relationship Studies on Tetrahydroisoquinoline Derivatives: [4′-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl)biphenyl-4-ol] (MC70) Conjugated through Flexible Alkyl Chains with Furazan Moieties Gives Rise to Potent and Selective Ligands of P-glycoprotein, file e27ce42a-1188-2581-e053-d805fe0acbaa
|
28
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Furoxan nitric oxide donors disperse Pseudomonas aeruginosa biofilms, accelerate growth, and repress pyoverdine production, file e27ce42b-e9f3-2581-e053-d805fe0acbaa
|
28
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|
Synthesis of Some Novel Organic Nitrates and Comparative in Vitro Study of Their Vasodilator Profile, file e27ce426-baf0-2581-e053-d805fe0acbaa
|
26
|
|
gem-Dinitroalkyl Benzenes: A Novel Class of IOP-Lowering Agents for the Treatment of Ocular Hypertension, file e27ce42c-8ff0-2581-e053-d805fe0acbaa
|
25
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|
EFFICIENTLY TARGETING DRUG EFFLUX THROUGH MODULATION OF P-GLYCOPROTEIN ACTIVITY BY SMALL MOLECULES: DESIGN, BIOLOGICAL AND COMPUTATIONAL STUDY., file e27ce42f-0382-2581-e053-d805fe0acbaa
|
25
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|
A Molecular Hybrid for Mitochondria-Targeted NO Photodelivery, file e27ce42c-8ff2-2581-e053-d805fe0acbaa
|
23
|
|
Fluorescent Nitric Oxide Photodonors Based on BODIPY and Rhodamine Antennae, file e27ce432-ebba-2581-e053-d805fe0acbaa
|
22
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|
Nitric Oxide Donor Doxorubicins Accumulate into Doxorubicin-Resistant Human Colon Cancer Cells Inducing Cytotoxicity, file e27ce426-c49c-2581-e053-d805fe0acbaa
|
21
|
|
Novel water soluble furoxan derivatives having antitumor activity, file e27ce427-0441-2581-e053-d805fe0acbaa
|
20
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|
A generator of peroxynitrite activatable with red light, file e27ce432-66d7-2581-e053-d805fe0acbaa
|
20
|
|
Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis, file e27ce429-f403-2581-e053-d805fe0acbaa
|
19
|
|
Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction, file 4e51e48a-5339-4c2d-bcb4-4dce51e5dddf
|
16
|
|
Galactosylated Prodrugs: A Strategy to Improve the Profile of Nonsteroidal Anti-Inflammatory Drugs, file 60b7fd36-6180-4e5a-b8f0-3745477faabf
|
16
|
|
(Nitrooxyacyloxy)methyl esters of aspirin as novel nitric oxide releasing aspirins, file e27ce426-b276-2581-e053-d805fe0acbaa
|
16
|
|
Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells, file e27ce426-dd5c-2581-e053-d805fe0acbaa
|
16
|
|
Synthesis physicochemical profile and PAMPA study of new NO-donor edaravone co-drugs, file e27ce426-d83b-2581-e053-d805fe0acbaa
|
13
|
|
Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells, file e27ce42e-114b-2581-e053-d805fe0acbaa
|
12
|
|
Fluorescent Nitric Oxide Photodonors Based on BODIPY and Rhodamine Antennae, file e27ce42e-af49-2581-e053-d805fe0acbaa
|
12
|
|
Paracetamol-Galactose Conjugate: A Novel Prodrug for an Old Analgesic Drug, file e27ce42e-df97-2581-e053-d805fe0acbaa
|
12
|
|
Cryo-EM undiscloses structural and mechanistic details on iron hijacking by Staphylococcus aureus: An insight into the interaction of IsdB hemophore with human hemoglobin, file 8857b9d2-5e3b-4ded-b2fb-7f8eabec9fff
|
6
|
|
A Nonmetal-Containing Nitric Oxide Donor Activated with Single-Photon Green Light, file e27ce42b-e9f5-2581-e053-d805fe0acbaa
|
6
|
|
Comparative Study of Different H2S Donors as Vasodilators and Attenuators of Superoxide-Induced Endothelial Damage, file e80b50e2-8b98-45e7-9ee5-3d72ab9566e8
|
6
|
|
Fluorescent Nitric Oxide Photodonors Based on BODIPY and Rhodamine Antennae, file e27ce42e-a491-2581-e053-d805fe0acbaa
|
5
|
|
Use of Enzymatically Activated Carbon Monoxide Donors for Sensitizing Drug-Resistant Tumor Cells, file 3576b7e4-3057-45d2-bb29-862a088242ed
|
4
|
|
Water-Soluble Nitric-Oxide-Releasing Acetylsalicylic Acid
(ASA) Prodrugs, file e27ce426-f7b5-2581-e053-d805fe0acbaa
|
4
|
|
Searching for new NO-donor aspirin-like molecules: furoxanylacyl derivatives of salicylic acid and related furazans, file e27ce427-cd40-2581-e053-d805fe0acbaa
|
4
|
|
Galactosylated Pro-Drug of Ursodeoxycholic Acid: Design, Synthesis, Characterization, and Pharmacological Effects in a Rat Model of Estrogen-Induced Cholestasis, file e27ce42c-84fa-2581-e053-d805fe0acbaa
|
4
|
|
Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells, file e27ce42e-83c9-2581-e053-d805fe0acbaa
|
4
|
|
NO in Viral Infections: Role and Development of Antiviral Therapies, file 73923a1e-b82b-4a56-b703-6b1e3bbe7395
|
3
|
|
Proteomics Studies Suggest That Nitric Oxide Donor Furoxans Inhibit In Vitro Vascular Smooth Muscle Cell Proliferation by Nitric Oxide-Independent Mechanisms †, file a429bdef-b5b3-49e5-997b-6117ecc70b4c
|
3
|
|
(Nitrooxyacyloxy)methyl esters of aspirin as novel nitric oxide releasing aspirins, file e27ce426-b5e2-2581-e053-d805fe0acbaa
|
3
|
|
Physicochemical profile and in vitro permeation behavior of a new class of non-steroidal anti-inflammatory drug candidates, file e27ce426-c4db-2581-e053-d805fe0acbaa
|
3
|
|
Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance., file e27ce426-e3e0-2581-e053-d805fe0acbaa
|
3
|
|
New furoxan derivatives for the treatment of ocular hypertension, file e27ce42b-615c-2581-e053-d805fe0acbaa
|
3
|
|
Furoxan nitric oxide donors disperse Pseudomonas aeruginosa biofilms, accelerate growth, and repress pyoverdine production, file e27ce42b-e9f2-2581-e053-d805fe0acbaa
|
3
|
|
Galactosylated Pro-Drug of Ursodeoxycholic Acid: Design, Synthesis, Characterization, and Pharmacological Effects in a Rat Model of Estrogen-Induced Cholestasis, file e27ce42c-b575-2581-e053-d805fe0acbaa
|
3
|
|
Tuning the Hydrophobicity of a Mitochondria-Targeted NO Photodonor, file e27ce42c-fa2c-2581-e053-d805fe0acbaa
|
3
|
|
Structure-Based Optimization of 1,2,4-Triazole-3-Thione Derivatives: Improving Inhibition of NDM-/VIM-Type Metallo-beta -Lactamases and Synergistic Activity on
Resistant Bacteria, file 7cb2c1bb-e4c6-4082-9833-e6a555fd4c89
|
2
|
|
Surface Functionalised Parenteral Nanoemulsions for Active and Homotypic Targeting to Melanoma, file d2f5705c-0ce6-4cbd-9550-bbad680cea5c
|
2
|
|
New lipophilic organic nitrates: Candidates for chronic skin disease therapy, file ddc0baf1-1e37-458b-8507-13ee2406149a
|
2
|
|
Structure-Antioxidant Activity Relationships in a Series of NO-Donor Phenols, file e27ce426-b041-2581-e053-d805fe0acbaa
|
2
|
|
Doxorubicin-antioxidant multitarget drugs, file e27ce426-f93c-2581-e053-d805fe0acbaa
|
2
|
|
Designing Multitarget Anti-inflammatory Agents: Chemical Modulation of the Lumiracoxib Structure toward Dual Thromboxane Antagonists-COX-2 Inhibitors., file e27ce427-bb7a-2581-e053-d805fe0acbaa
|
2
|
|
H2S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance, file e27ce428-bf7d-2581-e053-d805fe0acbaa
|
2
|
| Totale |
7.626 |