AMBROGIO, Chiara

AMBROGIO, Chiara  

BIOTECNOLOGIE MOLECOLARI E SCIENZE PER LA SALUTE  

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Titolo Data di pubblicazione Autore(i) File
A Braf kinase-inactive mutant induces lung adenocarcinoma 2017 Nieto P.; Ambrogio C.; Esteban-Burgos L.; Gomez-Lopez G.; Blasco M.T.; Yao Z.; Marais R.; Rosen N.; Chiarle R.; Pisano D.G.; Barbacid M.; Santamaria D.
A LIBRETTO to orchestrate targeted therapy 2020 Marmarelis, Melina E; Chiarle, Roberto; Ambrogio, Chiara; Aggarwal, Charu
A putative role for Discoidin Domain Receptor 1 in cancer chemoresistance 2018 Ambrogio C.; Darbo E.; Lee S.W.; Santamaria D.
A structural model of a Ras–Raf signalosome 2021 Mysore V.P.; Zhou Z.-W.; Ambrogio C.; Li L.; Kapp J.N.; Lu C.; Wang Q.; Tucker M.R.; Okoro J.J.; Nagy-Davidescu G.; Bai X.; Pluckthun A.; Janne P.A.; Westover K.D.; Shan Y.; Shaw D.E.
Ablation of oncogenic ALK is a viable therapeutic approach fAblation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas 2006 PIVA R; CHIARLE R; MANAZZA AD; TAULLI R; SIMMONS W; AMBROGIO C; D'ESCAMARD V; PELLEGRINO E; PONZETTO C; PALESTRO G; INGHIRAMI G
ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells 2023 Bergaggio, Elisa; Tai, Wei-Tien; Aroldi, Andrea; Mecca, Carmen; Landoni, Elisa; Nüesch, Manuel; Mota, Ines; Metovic, Jasna; Molinaro, Luca; Ma, Leyuan; Alvarado, Diego; Ambrogio, Chiara; Voena, Claudia; Blasco, Rafael B; Li, Tongqing; Klein, Daryl; Irvine, Darrell J; Papotti, Mauro; Savoldo, Barbara; Dotti, Gianpietro; Chiarle, Roberto
ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer 2023 Mota, Ines; Patrucco, Enrico; Mastini, Cristina; Mahadevan, Navin R; Thai, Tran C; Bergaggio, Elisa; Cheong, Taek-Chin; Leonardi, Giulia; Karaca-Atabay, Elif; Campisi, Marco; Poggio, Teresa; Menotti, Matteo; Ambrogio, Chiara; Longo, Dario L; Klaeger, Susan; Keshishian, Hasmik; Sztupinszki, Zsófia M; Szallasi, Zoltan; Keskin, Derin B; Duke-Cohan, Jonathan S; Reinhold, Bruce; Carr, Steven A; Wu, Catherine J; Moynihan, Kelly D; Irvine, Darrell J; Barbie, David A; Reinherz, Ellis L; Voena, Claudia; Awad, Mark M; Blasco, Rafael B; Chiarle, Roberto
ALK-dependent control of hypoxia-inducible factors mediates tumor growth and metastasis 2014 Martinengo, Cinzia; Poggio, Teresa; Menotti, Matteo; Scalzo, Maria Stella; Mastini, Cristina; Ambrogio, Chiara; Pellegrino, Elisa; Riera, Ludovica; Piva, Roberto; Ribatti, Domenico; Pastorino, Fabio; Perri, Patrizia; Ponzoni, Mirco; Wang, Qi; Voena, Claudia; Chiarle, Roberto
An integrative pharmacogenomics analysis identifies therapeutic targets in KRAS-mutant lung cancer 2019 Wang H.; Lv Q.; Xu Y.; Cai Z.; Zheng J.; Cheng X.; Dai Y.; Janne P.A.; Ambrogio C.; Kohler J.
Assessing therapeutic efficacy of MEK inhibition in a KrasG12C-driven mouse model of lung cancer 2018 Li S.; Liu S.; Deng J.; Akbay E.A.; Hai J.; Ambrogio C.; Zhang L.; Zhou F.; Jenkins R.W.; Adeegbe D.O.; Gao P.; Wang X.; Paweletz C.P.; Herter-Sprie G.S.; Chen T.; Gutierrez-Quiceno L.; Zhang Y.; Merlino A.A.; Quinn M.M.; Zeng Y.; Yu X.; Liu Y.; Fan L.; Aguirre A.J.; Barbie D.A.; Yi X.; Wong K.-K.
Biological and targeting differences between the rare KRAS A146T and canonical KRAS mutants in gastric cancer models 2024 Puliga, Elisabetta; De Bellis, Chiara; Vietti Michelina, Sandra; Capeloa, Tania; Migliore, Cristina; Orrù, Claudia; Baiocchi, Gian Luca; De Manzoni, Giovanni; Pietrantonio, Filippo; Reddavid, Rossella; Fumagalli Romario, Uberto; Ambrogio, Chiara; Corso, Simona; Giordano, Silvia
Cancer Hallmarks: Piecing the Puzzle Together 2024 Alcolea, Maria P.; Alonso-Curbelo, Direna; Ambrogio, Chiara; Bullman, Susan; Correia, Ana Luísa; Ernst, Aurélie; Halbrook, Christopher J.; Kelly, Gemma L.; Lund, Amanda W.; Quail, Daniela F.; Ruscetti, Marcus; Shema, Efrat; Stromnes, Ingunn M.; Tam, Wai Leong
Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma 2016 Ambrogio C.; Gomez-Lopez G.; Falcone M.; Vidal A.; Nadal E.; Crosetto N.; Blasco R.B.; Fernandez-Marcos P.J.; Sanchez-Cespedes M.; Ren X.; Wang Z.; Ding K.; Hidalgo M.; Serrano M.; Villanueva A.; Santamaraa D.; Barbacid M.
Comparative Analysis and Isoform-Specific Therapeutic Vulnerabilities of KRAS Mutations in Non-Small Cell Lung Cancer 2022 Ricciuti, Biagio; Son, Jieun; Okoro, Jeffrey J; Mira, Alessia; Patrucco, Enrico; Eum, Yoonji; Wang, Xinan; Paranal, Raymond; Wang, Haiyun; Lin, Mika; Haikala, Heidi M; Li, Jiaqi; Xu, Yue; Alessi, Joao Victor; Chhoeu, Chhayheng; Redig, Amanda J; Köhler, Jens; Dholakia, Kshiti H; Chen, Yunhan; Richard, Elodie; Nokin, Marie-Julie; Santamaria, David; Gokhale, Prafulla C; Awad, Mark M; Jänne, Pasi A; Ambrogio, Chiara
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy 2024 Holderfield, Matthew; Lee, Bianca J.; Jiang, Jingjing; Tomlinson, Aidan; Seamon, Kyle J.; Mira, Alessia; Patrucco, Enrico; Goodhart, Grace; Dilly, Julien; Gindin, Yevgeniy; Dinglasan, Nuntana; Wang, Yingyun; Lai, Lick Pui; Cai, Shurui; Jiang, Lingyan; Nasholm, Nicole; Shifrin, Nataliya; Blaj, Cristina; Shah, Harshit; Evans, James W.; Montazer, Nilufar; Lai, Oliver; Shi, Jade; Ahler, Ethan; Quintana, Elsa; Chang, Stephanie; Salvador, Anthony; Marquez, Abby; Cregg, Jim; Liu, Yang; Milin, Anthony; Chen, Anqi; Ziv, Tamar Bar; Parsons, Dylan; Knox, John E.; Klomp, Jennifer E.; Roth, Jennifer; Rees, Matthew; Ronan, Melissa; Cuevas-Navarro, Antonio; Hu, Feng; Lito, Piro; Santamaria, David; Aguirre, Andrew J.; Waters, Andrew M.; Der, Channing J.; Ambrogio, Chiara; Wang, Zhengping; Gill, Adrian L.; Koltun, Elena S.; Smith, Jacqueline A. M.; Wildes, David; Singh, Mallika
Discoveries in the redox regulation of KRAS 2021 Maximilian Kramer-Drauberg; Chiara Ambrogio
Dissecting the clinicopathologic, genomic, and immunophenotypic correlates of KRASG12D-mutated non-small-cell lung cancer 2022 Ricciuti, B; Alessi, J V; Elkrief, A; Wang, X; Cortellini, A; Li, Y Y; Vaz, V R; Gupta, H; Pecci, F; Barrichello, A; Lamberti, G; Nguyen, T; Lindsay, J; Sharma, B; Felt, K; Rodig, S J; Nishino, M; Sholl, L M; Barbie, D A; Negrao, M V; Zhang, J; Cherniack, A D; Heymach, J V; Meyerson, M; Ambrogio, C; Jänne, P A; Arbour, K C; Pinato, D J; Skoulidis, F; Schoenfeld, A J; Awad, M M; Luo, J
Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis 2022 Costamagna, Andrea; Natalini, Dora; Leal, Maria del Pilar Camacho; Simoni, Matilde; Gozzelino, Luca; Cappello, Paola; Novelli, Francesco; Ambrogio, Chiara; Defilippi, Paola; Turco, Emilia; Giovannetti, Elisa; Hirsch, Emilio; Cabodi, Sara; Martini, Miriam
Efficacy of a Cancer Vaccine against ALK-Rearranged Lung Tumors 2015 Voena, Claudia; Menotti, Matteo; Mastini, Cristina; Di Giacomo, Filomena; Longo, Dario Livio; Castella, Barbara; Merlo, Maria Elena Boggio; Ambrogio, Chiara; Wang, Qi; Minero, Valerio Giacomo; Poggio, Teresa; Martinengo, Cinzia; D'Amico, Lucia; Panizza, Elena; Mologni, Luca; Cavallo, Federica; Altruda, Fiorella; Butaney, Mohit; Capelletti, Marzia; Inghirami, Giorgio; Jänne, Pasi A; Chiarle, Roberto
ERK inhibitor LY3214996-based treatment strategies for RAS-driven lung cancer 2021 Köhler, Jens; Zhao, Yutong; Li, Jiaqi; Gokhale, Prafulla C; Tiv, Hong L; Knott, Aine R; Wilkens, Margaret K; Soroko, Kara M; Lin, Mika; Ambrogio, Chiara; Musteanu, Monica; Ogino, Atsuko; Choi, Jihyun; Bahcall, Magda; Bertram, Arrien A; Chambers, Emily S; Paweletz, Cloud P; Bhagwat, Shripad V; Manro, Jason R; Tiu, Ramon V; Janne, Pasi A