BOSCHI, Donatella

BOSCHI, Donatella  

SCIENZA E TECNOLOGIA DEL FARMACO  

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Titolo Data di pubblicazione Autore(i) File
1H-pyrazole-4-carboxylic acids active against Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH): discovery of a new scaffold for development of antimalarial agents 2014 Agnese Chiara Pippione; Ulf J. Nilsson; Ingela Fritzson; Anders P. Sundin; Salam Al-Karadaghi; Donatella Boschi; and Marco Lucio Lolli
4-Hydroxy-1,2,3-triazole moiety as bioisostere of the carboxylic acid function: a novel scaffold to probe the orthosteric γ-aminobutyric acid receptor binding site 2018 Giraudo, Alessandro; Krall, Jacob; Nielsen, Birgitte; Sørensen, Troels E.; Kongstad, Kenneth T.; Rolando, Barbara; Boschi, Donatella; Frølund, Bente; Lolli, Marco L.
4-Hydroxy-1H-1,2,3-Triazol-5-yl moiety as bioisoster of carboxylic group. Synthesis and pharmacological ionotropic glutamate receptors characterization of Glu analogues 2014 S. Sainas; A. Federico;C. Bertolotti; B. Nielsen; D. Boschi; B. Frølund and M. L. Lolli
4-Hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade 2017 Pippione, Agnese C.; Federico, Antonella; Ducime, Alex; Sainas, Stefano; Boschi, Donatella; Barge, Alessandro; Lupino, Elisa; Piccinini, Marco; Kubbutat, Michael; Contreras, Jean-Marie; Morice, Christophe; Al-Karadaghi, Salam; Lolli, Marco L.
6-Cyclohexylmethoxy-5-(cyano-NNO-azoxy)pyrimidine-4-amine: A new scaffold endowed with potent CDK2 inhibitory activity 2013 Boschi D.; Tosco P.; Chandra N.; Chaurasia S.; Fruttero R.*; Griffin R.; Wang L.-Z.; Gasco A.
A differentiating and apoptotic therapy for Acute Myeloid Leukaemia using MEDS433, a potent human Dihydroorotate Dehydrogenase inhibitor 2021 Stefano Sainas, Paola Circosta, Marta Giorgis, Agnese Chiara Pippione, Marilena Marraudino, Mohammad Houshmand, Brigitta Bonaldo, Valentina Gaidano, Alessandro Cignetti, Stefano Gotti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
A differentiating and apoptotic therapy for acute myeloid leukaemia using potent human dihydroorotate dehydrogenase inhibitors. 2019 Stefano Sainas, Agnese Chiara Pippione, Davide Bonanni, Marta Giorgis, Paola Circosta, Marilena Marraudino, Valentina Gaidano, Alessandro Cignetti, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Marco Lucio Lolli
A New NF-κB Inhibitor, MEDS-23, Reduces the Severity of Adverse Post-Ischemic Stroke Outcomes in Rats 2022 Rubin E.; Pippione A.C.; Boyko M.; Einaudi G.; Sainas S.; Collino M.; Cifani C.; Lolli M.L.; Abu-Freha N.; Kaplanski J.; Boschi D.; Azab A.N.
A new pro-apoptotic therapy for Acute Myeloid Leukaemia using MEDS433, a potent human Dihydroorotate Dehydrogenase inhibitor 2021 Sainas Sainas, Paola Circosta, Noemi Villella, Elena Martino, Agnese Chiara Pippione, Mohammad Houshmand, Marta Giorgis, Valentina Gaidano, Alessandro Cignetti, Caterina Peraldo Neia, Giovanna Chiorino, Salam Al-Karadaghi, Donatella Boschi, Giuseppe Saglio, Marco Lucio Lolli.
A New Synthetic Approach to Substituted β-Carboline Systems 1999 GIUSEPPE ERMONDI; SONJA VISENTIN; D. BOSCHI; ROBERTA FRUTTERO; ALBERTO GASCO
Activity of calvatic acid and its analogs against Helicobacter pylori 2001 BOSCHI D.; C. CENA; FRUTTERO R.; BRENCIAGLIA M. I.; SCALTRITO M. M.; DUBINI F.; GASCO A.
AKR1C3 is a biomarker and druggable target for oropharyngeal tumors 2021 Peraldo-Neia C.; Ostano P.; Mello-Grand M.; Guana F.; Gregnanin I.; Boschi D.; Oliaro-Bosso S.; Pippione A.C.; Carenzo A.; De Cecco L.; Cavalieri S.; Micali A.; Perrone F.; Averono G.; Bagnasacco P.; Dosdegani R.; Masini L.; Krengli M.; Aluffi-Valletti P.; Valente G.; Chiorino G.
ALPHA(1)-ADRENOCEPTOR BLOCKING ACTIVITY OF SOME RING-OPEN ANALOGS OF PRAZOSIN 1994 D. BOSCHI; A. DI STILO; R. FRUTTERO; C. MEDANA; G. SORBA; A. GASCO
Androgen-AR axis in primary and metastatic prostate cancer: chasing steroidogenic enzymes for therapeutic intervention 2017 Pippione, Agnese C.; Boschi, Donatella; Pors, Klaus; Oliaro-Bosso, Simonetta; Lolli, Marco L.
Antileishmanial activity of some 4-phenyl-3-amino-1H-pyrazols designed as CRK3 kinase inhibitors 2016 Agnese Chiara Pippione, Piermichele Kobauri, Stefano Sainas, Alberto Gimenez, Antonella Federico, Rodolpho Campos Braga, Carolina Horta Andrade, Donatella Boschi, Efrain Salamanca, Juan Carlos Ticona, Marco Lucio Lolli
Apoptotic and differentiating therapy for AML using potent human dihydroorotate dehydrogenase inhibitor 2021 Sainas Sainas, Circosta Paola, Pippione Agnese Chiara, Giorgis Marta, Marraudino Marilena, Houshmand Mohammad, Bonaldo Brigitta, Gaidano Valentina, Cignetti Alessandro, Saglio Giuseppe, Al-Karadaghi Salam, Boschi Donatella, Lolli Marco Lolli
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) 2019 Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro Bosso, Marco Lucio Lolli, Donatella Boschi
Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3) 2019 Chiara Vigato, Agnese Chiara Pippione, Sandra Kovachka, Francesca Spyrakis, Martina Daga, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Donatella Boschi
APPLICATION OF THE ARACHNO™ TECHNOLOGY FOR THE PARALLEL SYNTHESIS OF A LIBRARY OF ASPIRIN ANALOGUES 2015 Moreo, Angela; Barge, Alessandro; Boschi, Donatella; Costale, Annalisa; Dosio, Franco; Federico, Antonella; Stevanato, Livio; L. Lolli., Marco
Application of the arachno™ technology inside Educational fields: the introduction of parallel synthesis concepts inside an undergraduated lab 2016 L. Lolli, Marco; *a, ; Angela Moreo, B; Alessandro Barge, A; Donatella Boschi, A; Annalisa Costale, A; Livio Stevanatoa and Franco Dosioa