| Nome |
# |
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YAP activation is an early event and a potential therapeutic target in liver cancer development., file e27ce426-f13c-2581-e053-d805fe0acbaa
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627
|
|
The Dual Roles of NRF2 in Cancer, file e27ce429-be4b-2581-e053-d805fe0acbaa
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532
|
|
How Can Gastric Cancer Molecular Profiling Guide Future Therapies?, file e27ce429-be45-2581-e053-d805fe0acbaa
|
418
|
|
Targeted therapies for gastric cancer: failures and hopes from clinical trials, file e27ce42b-cd8f-2581-e053-d805fe0acbaa
|
325
|
|
Microsatellite instability in Gastric Cancer: Between lights and shadows, file e27ce434-d10f-2581-e053-d805fe0acbaa
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298
|
|
Rituximab Treatment Prevents Lymphoma Onset in Gastric Cancer Patient-Derived Xenografts, file e27ce42c-7d72-2581-e053-d805fe0acbaa
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260
|
|
Colorectal cancer early methylation alterations affect the crosstalk between cell and surrounding environment, tracing a biomarker signature specific for this tumor, file e27ce42c-b05b-2581-e053-d805fe0acbaa
|
241
|
|
Shedding-generated Met receptor fragments can be routed to either the proteasomal or the lysosomal degradation pathway., file e27ce426-cf0b-2581-e053-d805fe0acbaa
|
237
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|
Personalized therapeutic strategies in HER2-driven gastric cancer, file e27ce432-5232-2581-e053-d805fe0acbaa
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234
|
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Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis, file e27ce429-c05d-2581-e053-d805fe0acbaa
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231
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|
YAP-Dependent AXL Overexpression Mediates Resistance to EGFR Inhibitors in NSCLC, file e27ce42c-b21e-2581-e053-d805fe0acbaa
|
228
|
|
Cytokeratin-19 positivity is acquired along cancer progression and does not predict cell origin in rat hepatocarcinogenesis, file e27ce427-bb99-2581-e053-d805fe0acbaa
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198
|
|
MicroRNA/gene profiling unveils early molecular changes and NRF2 activation in a rat model recapitulating human HCC., file e27ce426-f832-2581-e053-d805fe0acbaa
|
189
|
|
BRAF and MEK inhibitors increase PD1-positive melanoma cells leading to a potential lymphocyte-independent synergism with anti-PD1 antibody, file e27ce42c-bad0-2581-e053-d805fe0acbaa
|
179
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|
Local hypothyroidism favours the progression of rat preneoplastic lesions to HCC., file e27ce426-f2c9-2581-e053-d805fe0acbaa
|
178
|
|
By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy., file e27ce426-9d2e-2581-e053-d805fe0acbaa
|
171
|
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A long term, non-tumorigenic rat hepatocyte cell line and its malignant counterpart, as tools to study hepatocarcinogenesis, file e27ce42c-2b46-2581-e053-d805fe0acbaa
|
145
|
|
MicroRNAs: New tools for diagnosis, prognosis and therapy in hepatocellular carcinoma?, file e27ce426-ec19-2581-e053-d805fe0acbaa
|
134
|
|
Cell-autonomous and non-cell-autonomous mechanisms of HGF/MET-driven resistance to targeted therapies: from basic research to a clinical perspective., file e27ce426-f981-2581-e053-d805fe0acbaa
|
122
|
|
miR-205 mediates adaptive resistance to MET inhibition via ERRFI1 targeting and raised EGFR signaling, file e27ce42c-d32d-2581-e053-d805fe0acbaa
|
121
|
|
Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies, file e27ce42d-ea3c-2581-e053-d805fe0acbaa
|
117
|
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Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies, file e27ce42d-22a0-2581-e053-d805fe0acbaa
|
109
|
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ErbB2 and bone sialoprotein as markers for metastatic osteosarcoma cells., file e27ce42f-6b49-2581-e053-d805fe0acbaa
|
92
|
|
Activation of RAS family members confers resistance to ROS1 targeting drugs., file e27ce427-03f3-2581-e053-d805fe0acbaa
|
91
|
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Potential role of two novel agonists of thyroid hormone receptor-β on liver regeneration, file e27ce432-7c58-2581-e053-d805fe0acbaa
|
90
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Clinical implications of DNA repair defects in high-grade serous ovarian carcinomas, file e27ce42f-d57d-2581-e053-d805fe0acbaa
|
84
|
|
MiR-100 is a predictor of endocrine responsiveness and prognosis in patients with operable luminal breast cancer, file e27ce430-fc55-2581-e053-d805fe0acbaa
|
81
|
|
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts, file e27ce431-0751-2581-e053-d805fe0acbaa
|
80
|
|
Molecularly targeted therapies for gastric cancer. State of the art, file e27ce432-7677-2581-e053-d805fe0acbaa
|
68
|
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MET and KRAS gene amplification mediates acquired resistance to MET tyrosine kinase inhibitors., file e27ce426-ca6d-2581-e053-d805fe0acbaa
|
62
|
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The landscape of d16HER2 splice variant expression across HER2-positive cancers, file e27ce42f-f9f1-2581-e053-d805fe0acbaa
|
60
|
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Downregulating Neuropilin-2 Triggers a Novel Mechanism Enabling EGFR-Dependent Resistance to Oncogene-Targeted Therapies, file e27ce42c-b2a3-2581-e053-d805fe0acbaa
|
59
|
|
Only a subset of Met-activated pathways are required to sustain oncogene addiction, file e27ce426-c444-2581-e053-d805fe0acbaa
|
56
|
|
Sequential analysis of multistage hepatocarcinogenesis reveals that miR-100 and PLK1 dysregulation is an early event maintained along tumor progression., file e27ce426-d777-2581-e053-d805fe0acbaa
|
53
|
|
Optimized EGFR blockade strategies in EGFR addicted gastroesophageal adenocarcinomas, file e27ce432-759d-2581-e053-d805fe0acbaa
|
53
|
|
Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear receptor ligands: TCPOBOP and T3, file e27ce426-d712-2581-e053-d805fe0acbaa
|
49
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A novel strategy for combination of clofarabine and pictilisib is synergistic in gastric cancer, file e27ce433-8dbb-2581-e053-d805fe0acbaa
|
49
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|
Autocrine signaling of NRP1 ligand galectin-1 elicits resistance to BRAF-targeted therapy in melanoma cells, file e27ce432-4d51-2581-e053-d805fe0acbaa
|
42
|
|
Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice., file e27ce426-d714-2581-e053-d805fe0acbaa
|
39
|
|
Nrf2, but not β-catenin, mutation represents an early event in rat hepatocarcinogenesis., file e27ce427-4967-2581-e053-d805fe0acbaa
|
39
|
|
Biomarkers of Primary Resistance to Trastuzumab in HER2-Positive Metastatic Gastric Cancer Patients: the AMNESIA Case-Control Study, file e27ce42c-7f58-2581-e053-d805fe0acbaa
|
35
|
|
Enhanced c-Met activity promotes G-CSF induced mobilization of hematopoietic progenitor cells via ROS signaling., file e27ce426-bea6-2581-e053-d805fe0acbaa
|
34
|
|
Diverse MicroRNAs-mRNA networks regulate the priming phase of mouse liver regeneration and of direct hyperplasia, file e27ce435-1485-2581-e053-d805fe0acbaa
|
34
|
|
Nrf2 Mutation/Activation Is Dispensable for the Development of Chemically Induced Mouse HCC., file e27ce433-ed86-2581-e053-d805fe0acbaa
|
32
|
|
Met as a therapeutic target in HCC: Facts and hopes., file e27ce426-f928-2581-e053-d805fe0acbaa
|
25
|
|
A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine, file e27ce435-5c59-2581-e053-d805fe0acbaa
|
25
|
|
Amplification of the MET Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer., file e27ce426-e096-2581-e053-d805fe0acbaa
|
22
|
|
Resistance to targeted therapies: a role for microRNAs?, file e27ce426-febf-2581-e053-d805fe0acbaa
|
22
|
|
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts, file e27ce431-0557-2581-e053-d805fe0acbaa
|
22
|
|
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts, file 52c30ba5-92de-4264-8774-48ec22157379
|
19
|
|
hOA-DN30: a highly effective humanized single-arm MET antibody inducing remission of ‘MET-addicted’ cancers, file e27ce435-48c8-2581-e053-d805fe0acbaa
|
18
|
|
Targeted therapies in cancer and mechanisms of resistance., file e27ce426-ef90-2581-e053-d805fe0acbaa
|
14
|
|
Increase of MET gene copy number confers resistance to a monovalent MET antibody and establishes drug dependence., file e27ce426-f472-2581-e053-d805fe0acbaa
|
14
|
|
HER2 copy number and resistance mechanisms in patients with HER2-positive advanced gastric cancer receiving initial trastuzumab-based therapy in JACOB trial, file 87e000eb-c317-4ed5-89ba-d74138787577
|
12
|
|
Efficacy of CAR-T immunotherapy in MET overexpressing tumors not eligible for anti-MET targeted therapy, file 505c7d60-5416-4cc6-b7df-52d88f6410fe
|
11
|
|
Optimized EGFR blockade strategies in EGFR addicted gastroesophageal adenocarcinomas, file e27ce435-9762-2581-e053-d805fe0acbaa
|
11
|
|
The importance of being CAFs (in cancer resistance to targeted therapies), file f01d5f66-9da2-435d-82ec-4d28676e6d21
|
9
|
|
The Tumor-Specific Expression of L1 Retrotransposons Independently Correlates with Time to Relapse in Hormone-Negative Breast Cancer Patients, file 1dd1ef0b-6a20-496b-bda2-7630e41be975
|
7
|
|
A comprehensive PDX gastric cancer collection captures cancer cell intrinsic transcriptional MSI traits, file e27ce42f-0282-2581-e053-d805fe0acbaa
|
7
|
|
The metabolic gene HAO2 is downregulated in hepatocellular carcinoma and predicts metastasis and poor survival, file e27ce428-c9df-2581-e053-d805fe0acbaa
|
6
|
|
Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming, file 444f2bdc-a378-46c1-bdf4-480c680a1a23
|
4
|
|
HER2-positive breast cancer cells resistant to trastuzumab and lapatinib lose reliance upon HER2 and are sensitive to the multitargeted kinase inhibitor sorafenib, file e27ce426-c5d7-2581-e053-d805fe0acbaa
|
4
|
|
Patient-Derived Orthotopic Xenograft models in gastric cancer: a systematic review, file e27ce430-e119-2581-e053-d805fe0acbaa
|
4
|
|
Fatty acid synthase as a new therapeutic target for HER2-positive gastric cancer, file a3476429-174d-4de8-9faa-f2f292ff8abe
|
3
|
|
Fatty acid synthase as a new therapeutic target for HER2-positive gastric cancer, file bc30e98f-bce2-4f3f-8c22-a3387201ebd3
|
3
|
|
BRCA2 Germline Mutations Identify Gastric Cancers Responsive to PARP Inhibitors, file de8bf275-2b9f-4f0d-b7bd-f97ce3cfc3be
|
3
|
|
Biomarkers of Primary Resistance to Trastuzumab in HER2-Positive Metastatic Gastric Cancer Patients: the AMNESIA Case-Control Study, file e27ce42c-8b69-2581-e053-d805fe0acbaa
|
3
|
|
MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer., file e27ce426-d775-2581-e053-d805fe0acbaa
|
2
|
|
Human ASH-1 Promotes Neuroendocrine Differentiation in Androgen Deprivation Conditions and Interferes With Androgen Responsiveness in Prostate Cancer Cells., file e27ce426-e09e-2581-e053-d805fe0acbaa
|
2
|
|
MicroRNA/gene profiling unveils early molecular changes and NRF2 activation in a rat model recapitulating human HCC., file e27ce426-f831-2581-e053-d805fe0acbaa
|
2
|
|
The metabolic gene HAO2 is downregulated in hepatocellular carcinoma and predicts metastasis and poor survival, file e27ce428-c32c-2581-e053-d805fe0acbaa
|
2
|
|
Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies, file e27ce432-5941-2581-e053-d805fe0acbaa
|
2
|
|
Only a subset of Met-activated pathways are required to sustain oncogene addiction, file e27ce426-c443-2581-e053-d805fe0acbaa
|
1
|
|
Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition., file e27ce426-ca71-2581-e053-d805fe0acbaa
|
1
|
|
Dual MET/EGFR therapy leads to complete response and resistance prevention in a MET-amplified gastroesophageal xenopatient cohort, file e27ce429-be4c-2581-e053-d805fe0acbaa
|
1
|
|
Downregulating Neuropilin-2 Triggers a Novel Mechanism Enabling EGFR-Dependent Resistance to Oncogene-Targeted Therapies, file e27ce42c-634f-2581-e053-d805fe0acbaa
|
1
|
|
Chest wall infiltration is a critical prognostic factor in breast implant-associated anaplastic large-cell lymphoma affected patients, file e27ce432-4e2f-2581-e053-d805fe0acbaa
|
1
|
|
FGFR2 fusion proteins drive oncogenic transformation of mouse liver organoids towards cholangiocarcinoma, file e27ce432-8fc6-2581-e053-d805fe0acbaa
|
1
|
| Totale |
6.860 |