FRANCO, IRENE
FRANCO, IRENE
Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice
2014-01-01 Barutta F; Grimaldi S; Franco I; Bellini S; Gambino R; Pinach S; Corbelli A; Bruno G; Rastaldi MP; Aveta T; Hirsch E; Di Marzo V; Gruden G
Distinct Effects of Leukocyte and Cardiac Phosphoinositide 3-Kinase {gamma} Activity in Pressure Overload-Induced Cardiac Failure
2011-01-01 Damilano F; Franco I; Perrino C; Schaefer K; Azzolino O; Carnevale D; Cifelli G; Carullo P; Ragona R; Ghigo A; Perino A; Lembo G; Hirsch E
Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function
2017-01-01 Gulluni, Federico; Martini, Miriam; De Santis, Maria Chiara; Campa, Carlo Cosimo; Ghigo, Alessandra; Margaria, Jean Piero; Ciraolo, Elisa; Franco, Irene; Ala, Ugo; Annaratone, Laura; Disalvatore, Davide; Bertalot, Giovanni; Viale, Giuseppe; Noatynska, Anna; Compagno, Mara; Sigismund, Sara; Montemurro, Filippo; Thelen, Marcus; Fan, Fan; Meraldi, Patrick; Marchiò, Caterina; Pece, Salvatore; Sapino, Anna; Chiarle, Roberto; Di Fiore, Pier Paolo; Hirsch, Emilio
Morgana acts as an oncosuppressor in chronic myeloid leukemia.
2015-01-01 Di Savino A;Panuzzo C;Rocca S;Familiari U;Piazza R;Crivellaro S;Carrà G;Ferretti R;Fusella F;Giugliano E;Camporeale A;Franco I;Miniscalco B;Cutrin JC;Turco E;Silengo L;Hirsch E;Rege-Cambrin G;Gambacorti-Passerini C;Pandolfi PP;Papotti M;Saglio G;Tarone G;Morotti A;Brancaccio M
Myocyte signalling in leucocyte recruitment to the heart.
2014-01-01 Ghigo A;Franco I;Morello F;Hirsch E
Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth
2018-01-01 Li, Mingchuan; Sala, Valentina; De Santis, Maria Chiara; Cimino, James; Cappello, Paola; Pianca, Nicola; Di Bona, Anna; Margaria, Jean Piero; Martini, Miriam; Lazzarini, Edoardo; Pirozzi, Flora; Rossi, Luca; Franco, Irene; Bornbaum, Julia; Heger, Jacqueline; Rohrbach, Susanne; Perino, Alessia; Tocchetti, Carlo G; Lima, Braulio H F; Teixeira, Mauro M; Porporato, Paolo E; Schulz, Rainer; Angelini, Annalisa; Sandri, Marco; Ameri, Pietro; Sciarretta, Sebastiano; Lima-Júnior, Roberto César P; Mongillo, Marco; Zaglia, Tania; Morello, Fulvio; Novelli, Francesco; Hirsch, Emilio; Ghigo, Alessandra
Phosphoinositide 3-Kinase γ Restrains Neurotoxic Effects of Microglia After Focal Brain Ischemia
2016-01-01 Schmidt C.; Frahm C.; Schneble N.; Muller J.P.; Brodhun M.; Franco I.; Witte O.W.; Hirsch E.; Wetzker R.; Bauer R.
Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation
2016-01-01 Franco, Irene; Margaria, Jean Piero; De Santis, Maria Chiara; Ranghino, Andrea; Monteyne, Daniel; Chiaravalli, Marco; Pema, Monika; Campa, Carlo Cosimo; Ratto, Edoardo; Gulluni, Federico; Perez-Morga, David; Somlo, Stefan; Merlo, Giorgio R; Boletta, Alessandra; Hirsch, Emilio
PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth.
2013-01-01 Schmid MC;Franco I;Kang SW;Hirsch E;Quilliam LA;Varner JA
PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function.
2014-01-01 Franco I;Gulluni F;Campa CC;Costa C;Margaria JP;Ciraolo E;Martini M;Monteyne D;De Luca E;Germena G;Posor Y;Maffucci T;Marengo S;Haucke V;Falasca M;Perez-Morga D;Boletta A;Merlo GR;Hirsch E
PI3K in cancer-stroma interactions: bad in seed and ugly in soil.
2014-01-01 Hirsch E;Ciraolo E;Franco I;Ghigo A;Martini M
PI3K-C2α: One enzyme for two products coupling vesicle trafficking and signal transduction
2015-01-01 Campa, Carlo C; Franco, Irene; Hirsch, Emilio
Rac signal adaptation controls neutrophil mobilization from the bone marrow
2016-01-01 Campa, Carlo Cosimo; Germena, Giulia; Ciraolo, Elisa; Copperi, Francesca; Sapienza, Anna; Franco, Irene; Ghigo, Alessandra; Camporeale, Annalisa; Di Savino, Augusta; Martini, Miriam; Perino, Alessia; Megens, Remco T.A.; Kurz, Angela R.M.; Scheiermann, Christoph; Sperandio, Markus; Gamba, Andrea; Hirsch, Emilio
The absence of functional PI3Kgamma prevents leukocyte recruitment and amelioratesDSS-induced colitis in mice
2010-01-01 van Dop WA; Marengo S; Te Velde AA; Ciraolo E; Franco I; Ten Kate FJ; Boeckxstaens GE; Hardwick JC; Hommes DW; Hirsch E; van den Brink GR
The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation.
2014-01-01 Fan CW;Chen B;Franco I;Lu J;Shi H;Wei S;Wang C;Wu X;Tang W;Roth MG;Williams NS;Hirsch E;Chen C;Lum L
The PI3K/Akt/mTOR pathway in polycystic kidney disease: A complex interaction with polycystins and primary cilium
2020-01-01 Margaria J.P.; Campa C.C.; De Santis M.C.; Hirsch E.; Franco I.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice | 2014 | Barutta F; Grimaldi S; Franco I; Bellini S; Gambino R; Pinach S; Corbelli A; Bruno G; Rastaldi MP; Aveta T; Hirsch E; Di Marzo V; Gruden G | |
| Distinct Effects of Leukocyte and Cardiac Phosphoinositide 3-Kinase {gamma} Activity in Pressure Overload-Induced Cardiac Failure | 2011 | Damilano F; Franco I; Perrino C; Schaefer K; Azzolino O; Carnevale D; Cifelli G; Carullo P; Ragona R; Ghigo A; Perino A; Lembo G; Hirsch E | |
| Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function | 2017 | Gulluni, Federico; Martini, Miriam; De Santis, Maria Chiara; Campa, Carlo Cosimo; Ghigo, Alessandra; Margaria, Jean Piero; Ciraolo, Elisa; Franco, Irene; Ala, Ugo; Annaratone, Laura; Disalvatore, Davide; Bertalot, Giovanni; Viale, Giuseppe; Noatynska, Anna; Compagno, Mara; Sigismund, Sara; Montemurro, Filippo; Thelen, Marcus; Fan, Fan; Meraldi, Patrick; Marchiò, Caterina; Pece, Salvatore; Sapino, Anna; Chiarle, Roberto; Di Fiore, Pier Paolo; Hirsch, Emilio | |
| Morgana acts as an oncosuppressor in chronic myeloid leukemia. | 2015 | Di Savino A;Panuzzo C;Rocca S;Familiari U;Piazza R;Crivellaro S;Carrà G;Ferretti R;Fusella F;Giugliano E;Camporeale A;Franco I;Miniscalco B;Cutrin JC;Turco E;Silengo L;Hirsch E;Rege-Cambrin G;Gambacorti-Passerini C;Pandolfi PP;Papotti M;Saglio G;Tarone G;Morotti A;Brancaccio M | |
| Myocyte signalling in leucocyte recruitment to the heart. | 2014 | Ghigo A;Franco I;Morello F;Hirsch E | |
| Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth | 2018 | Li, Mingchuan; Sala, Valentina; De Santis, Maria Chiara; Cimino, James; Cappello, Paola; Pianca, Nicola; Di Bona, Anna; Margaria, Jean Piero; Martini, Miriam; Lazzarini, Edoardo; Pirozzi, Flora; Rossi, Luca; Franco, Irene; Bornbaum, Julia; Heger, Jacqueline; Rohrbach, Susanne; Perino, Alessia; Tocchetti, Carlo G; Lima, Braulio H F; Teixeira, Mauro M; Porporato, Paolo E; Schulz, Rainer; Angelini, Annalisa; Sandri, Marco; Ameri, Pietro; Sciarretta, Sebastiano; Lima-Júnior, Roberto César P; Mongillo, Marco; Zaglia, Tania; Morello, Fulvio; Novelli, Francesco; Hirsch, Emilio; Ghigo, Alessandra | |
| Phosphoinositide 3-Kinase γ Restrains Neurotoxic Effects of Microglia After Focal Brain Ischemia | 2016 | Schmidt C.; Frahm C.; Schneble N.; Muller J.P.; Brodhun M.; Franco I.; Witte O.W.; Hirsch E.; Wetzker R.; Bauer R. | |
| Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation | 2016 | Franco, Irene; Margaria, Jean Piero; De Santis, Maria Chiara; Ranghino, Andrea; Monteyne, Daniel; Chiaravalli, Marco; Pema, Monika; Campa, Carlo Cosimo; Ratto, Edoardo; Gulluni, Federico; Perez-Morga, David; Somlo, Stefan; Merlo, Giorgio R; Boletta, Alessandra; Hirsch, Emilio | |
| PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth. | 2013 | Schmid MC;Franco I;Kang SW;Hirsch E;Quilliam LA;Varner JA | |
| PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function. | 2014 | Franco I;Gulluni F;Campa CC;Costa C;Margaria JP;Ciraolo E;Martini M;Monteyne D;De Luca E;Germena G;Posor Y;Maffucci T;Marengo S;Haucke V;Falasca M;Perez-Morga D;Boletta A;Merlo GR;Hirsch E | |
| PI3K in cancer-stroma interactions: bad in seed and ugly in soil. | 2014 | Hirsch E;Ciraolo E;Franco I;Ghigo A;Martini M | |
| PI3K-C2α: One enzyme for two products coupling vesicle trafficking and signal transduction | 2015 | Campa, Carlo C; Franco, Irene; Hirsch, Emilio | |
| Rac signal adaptation controls neutrophil mobilization from the bone marrow | 2016 | Campa, Carlo Cosimo; Germena, Giulia; Ciraolo, Elisa; Copperi, Francesca; Sapienza, Anna; Franco, Irene; Ghigo, Alessandra; Camporeale, Annalisa; Di Savino, Augusta; Martini, Miriam; Perino, Alessia; Megens, Remco T.A.; Kurz, Angela R.M.; Scheiermann, Christoph; Sperandio, Markus; Gamba, Andrea; Hirsch, Emilio | |
| The absence of functional PI3Kgamma prevents leukocyte recruitment and amelioratesDSS-induced colitis in mice | 2010 | van Dop WA; Marengo S; Te Velde AA; Ciraolo E; Franco I; Ten Kate FJ; Boeckxstaens GE; Hardwick JC; Hommes DW; Hirsch E; van den Brink GR | |
| The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation. | 2014 | Fan CW;Chen B;Franco I;Lu J;Shi H;Wei S;Wang C;Wu X;Tang W;Roth MG;Williams NS;Hirsch E;Chen C;Lum L | |
| The PI3K/Akt/mTOR pathway in polycystic kidney disease: A complex interaction with polycystins and primary cilium | 2020 | Margaria J.P.; Campa C.C.; De Santis M.C.; Hirsch E.; Franco I. |