LAZZARI, LUCA
LAZZARI, LUCA
ONCOLOGIA
223P Artificial intelligence-based pathomics biomarker predict primary resistance to first-line treatment in metastatic colorectal cancers
2023-01-01 Mauri, G.; Giannini, V.; Nicoletti, G.; Lazzari, L.; Sartore Bianchi, A.; Marmorino, F.; Randon, G.; Nieva Munoz, M.; Saoudi Gonzalez, N.; Puccini, A.; Berrino, E.; Marchiò, C.; Di Como, M.; Aquilano, M.C.; Arena, S.; Torri, V.; Siena, S.; Bardelli, A.; Regge, D.; Marsoni, S.
Abstract B33: The oligoclonal antibody MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancer cells harboring EGFR extracellular domain mutations
2016-01-01 Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex; Montagut, Clara; Nicolantonio, Federica Di; Nering, Rachel; Bardelli, Alberto
Abstract LB-299: A comprehensive platform of patient-derived xenografts and matched cell lines mirrors the genomic landscape of colorectal cancer
2019-01-01 Lazzari, Luca; Corti, Giorgio; Isella, Claudio; Montone, Monica; Arcella, Pamela; Zanella, Eugenia; Novara, Luca; Barbosa, Fabiane; Cassingena, Andrea; Cancelliere, Carlotta; Medico, Enzo; Sartore-Bianchi, Andrea; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Nicolantonio, Federica Di; Linnebacher, Michael; Bardelli, Alberto; Arena, Sabrina
Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer
2016-01-01 Van Emburgh, Beth O; Arena, Sabrina; Siravegna, Giulia; Lazzari, Luca; Crisafulli, Giovanni; Corti, Giorgio; Mussolin, Benedetta; Baldi, Federica; Buscarino, Michela; Bartolini, Alice; Valtorta, Emanuele; Vidal, Joana; Bellosillo, Beatriz; Germano, Giovanni; Pietrantonio, Filippo; Ponzetti, Agostino; Albanell, Joan; Siena, Salvatore; Sartore-Bianchi, Andrea; Di Nicolantonio, Federica; Montagut, Clara; Bardelli, Alberto
Acquired resistance to the TRK inhibitor entrectinib in colorectal cancer
2016-01-01 Russo, Mariangela; Misale, Sandra; Wei, Ge; Siravegna, Giulia; Crisafulli, Giovanni; Lazzari, Luca; Corti, Giorgio; Rospo, Giuseppe; Novara, Luca; Mussolin, Benedetta; Bartolini, Alice; Cam, Nicholas; Patel, Roopal; Yan, Shunqi; Shoemaker, Robert; Wild, Robert; Di Nicolantonio, Federica; Sartore-Bianchi, Andrea; Li, Gang; Siena, Salvatore; Bardelli, Alberto
ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer
2017-01-01 Pietrantonio, Filippo*; Di Nicolantonio, Federica*; Schrock, Alexa B; Lee, Jeeyun; Tejpar, Sabine; Sartore-Bianchi, Andrea; Hechtman, Jaclyn F; Christiansen, Jason; Novara, Luca; Tebbutt, Niall; Fucà, Giovanni; Antoniotti, Carlotta; Kim, Seung Tae; Murphy, Danielle; Berenato, Rosa; Morano, Federica; Sun, James; Min, Bosun; Stephens, Philip J; Chen, Marissa; Lazzari, Luca; Miller, Vincent A; Shoemaker, Robert; Amatu, Alessio; Milione, Massimo; Ross, Jeffrey S; Siena, Salvatore; Bardelli, Alberto; Ali, Siraj M; Falcone, Alfredo; de Braud, Filippo; Cremolini, Chiara; *corresponding authors
An 'in-cell trial' to assess the efficacy of a monovalent anti-MET antibody as monotherapy and in association with standard cytotoxics.
2014-01-01 Benvenuti S;Gentile A;Lazzari L;Arnesano A;Trusolino L;Comoglio PM
Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer
2014-01-01 S. Misale;S. Arena;S. Lamba;G. Siravegna;A. Lallo;S. Hobor;M. Russo;M. Buscarino;L. Lazzari;A. Sartore-Bianchi;K. Bencardino;A. Amatu;C. Lauricella;E. Valtorta;S. Siena;F. Di Nicolantonio;A. Bardelli
Emergence of multiple EGFR extracellular mutations during cetuximab treatment in colorectal cancer
2015-01-01 S. Arena; B. Bellosillo; G. Siravegna; A. Martinez; I. Canadas; L. Lazzari; N. Ferruz; M. Russo; S. Misale; I. Gonzalez; M. Iglesias; E. Gavilan; G. Corti; S. Hobor; G. Crisafulli; M. Salido; J. Sanchez; A. Dalmases; J. Bellmunt; G.D. Fabritiis; A. Rovira; F. Di Nicolantonio; J. Albanell; A. Bardelli; C. Montagut
Met-driven invasive growth involves transcriptional regulation of Arhgap12
2008-01-01 Gentile A; D'Alessandro L; Lazzari L; Martinoglio B; Bertotti A; Mira A; Lanzetti L; Comoglio PM; Medico E.
MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations
2016-01-01 Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex A.; Montagut, Clara; Di Nicolantonio, Federica; Nering, Rachel; Bardelli, Alberto
PO-050 A molecularly annotated platform of pdx-derived cell lines mirrors the genomic landscape of colorectal cancer
2018-01-01 Lazzari, L.; Corti, G.; Isella, C.; Montone, M.; Bertotti, A.; Trusolino, L.; Nicolantonio, F. Di; Linnebacher, M.; Bardelli, A.; Arena, S.
RAF suppression synergizes with MEK inhibition in KRAS mutant cancer cells.
2014-01-01 Lamba S;Russo M;Sun C;Lazzari L;Cancelliere C;Grernrum W;Lieftink C;Bernards R;Di Nicolantonio F*;Bardelli A* (*co-last and * co-corresponding authors)
Ron kinase transphosphorylation sustains MET oncogene addiction
2011-01-01 S. Benvenuti; L. Lazzari; A. Arnesano; G. Li Chiavi; A. Gentile; P.M. Comoglio
Ror1 is a pseudokinase that is crucial for Met-driven tumorigenesis
2011-01-01 Gentile A; Lazzari L; Benvenuti S; Trusolino L*; Comoglio PM* (*Corresponding Authors)
The ROR1 pseudokinase diversifies signaling outputs in MET-addicted cancer cells.
2014-01-01 Gentile A;Lazzari L;Benvenuti S;Trusolino L;Comoglio PM
Tumor heterogeneity and Lesion-Specific response to targeted therapy in colorectal cancer
2016-01-01 Russo, Mariangela; Siravegna, Giulia; Blaszkowsky, Lawrence S.; Corti, Giorgio; Crisafulli, Giovanni; Ahronian, Leanne G.; Mussolin, Benedetta; Kwak, Eunice L.; Buscarino, Michela; Lazzari, Luca; Valtorta, Emanuele; Truini, Mauro; Jessop, Nicholas A.; Robinson, Hayley E.; Hong, Theodore S.; Mino-Kenudson, Mari; Di Nicolantonio, Federica; Thabet, Ashraf; Sartore-Bianchi, Andrea; Siena, Salvatore; Iafrate, John; Bardelli, Alberto; ^*; Corcoran, Ryan B.; ^*; ^ joint co-last authorship; *joint corresponding authorship
Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer
2020-01-01 Lorenzato, Annalisa; Magrì, Alessandro; Matafora, Vittoria; Audrito, Valentina; Arcella, Pamela; Lazzari, Luca; Montone, Monica; Lamba, Simona; Deaglio, Silvia; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Bachi, Angela; Di Nicolantonio, Federica; Bardelli, Alberto; Arena, Sabrina
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 223P Artificial intelligence-based pathomics biomarker predict primary resistance to first-line treatment in metastatic colorectal cancers | 2023 | Mauri, G.; Giannini, V.; Nicoletti, G.; Lazzari, L.; Sartore Bianchi, A.; Marmorino, F.; Randon, G.; Nieva Munoz, M.; Saoudi Gonzalez, N.; Puccini, A.; Berrino, E.; Marchiò, C.; Di Como, M.; Aquilano, M.C.; Arena, S.; Torri, V.; Siena, S.; Bardelli, A.; Regge, D.; Marsoni, S. | |
| Abstract B33: The oligoclonal antibody MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancer cells harboring EGFR extracellular domain mutations | 2016 | Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex; Montagut, Clara; Nicolantonio, Federica Di; Nering, Rachel; Bardelli, Alberto | |
| Abstract LB-299: A comprehensive platform of patient-derived xenografts and matched cell lines mirrors the genomic landscape of colorectal cancer | 2019 | Lazzari, Luca; Corti, Giorgio; Isella, Claudio; Montone, Monica; Arcella, Pamela; Zanella, Eugenia; Novara, Luca; Barbosa, Fabiane; Cassingena, Andrea; Cancelliere, Carlotta; Medico, Enzo; Sartore-Bianchi, Andrea; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Nicolantonio, Federica Di; Linnebacher, Michael; Bardelli, Alberto; Arena, Sabrina | |
| Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer | 2016 | Van Emburgh, Beth O; Arena, Sabrina; Siravegna, Giulia; Lazzari, Luca; Crisafulli, Giovanni; Corti, Giorgio; Mussolin, Benedetta; Baldi, Federica; Buscarino, Michela; Bartolini, Alice; Valtorta, Emanuele; Vidal, Joana; Bellosillo, Beatriz; Germano, Giovanni; Pietrantonio, Filippo; Ponzetti, Agostino; Albanell, Joan; Siena, Salvatore; Sartore-Bianchi, Andrea; Di Nicolantonio, Federica; Montagut, Clara; Bardelli, Alberto | |
| Acquired resistance to the TRK inhibitor entrectinib in colorectal cancer | 2016 | Russo, Mariangela; Misale, Sandra; Wei, Ge; Siravegna, Giulia; Crisafulli, Giovanni; Lazzari, Luca; Corti, Giorgio; Rospo, Giuseppe; Novara, Luca; Mussolin, Benedetta; Bartolini, Alice; Cam, Nicholas; Patel, Roopal; Yan, Shunqi; Shoemaker, Robert; Wild, Robert; Di Nicolantonio, Federica; Sartore-Bianchi, Andrea; Li, Gang; Siena, Salvatore; Bardelli, Alberto | |
| ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer | 2017 | Pietrantonio, Filippo*; Di Nicolantonio, Federica*; Schrock, Alexa B; Lee, Jeeyun; Tejpar, Sabine; Sartore-Bianchi, Andrea; Hechtman, Jaclyn F; Christiansen, Jason; Novara, Luca; Tebbutt, Niall; Fucà, Giovanni; Antoniotti, Carlotta; Kim, Seung Tae; Murphy, Danielle; Berenato, Rosa; Morano, Federica; Sun, James; Min, Bosun; Stephens, Philip J; Chen, Marissa; Lazzari, Luca; Miller, Vincent A; Shoemaker, Robert; Amatu, Alessio; Milione, Massimo; Ross, Jeffrey S; Siena, Salvatore; Bardelli, Alberto; Ali, Siraj M; Falcone, Alfredo; de Braud, Filippo; Cremolini, Chiara; *corresponding authors | |
| An 'in-cell trial' to assess the efficacy of a monovalent anti-MET antibody as monotherapy and in association with standard cytotoxics. | 2014 | Benvenuti S;Gentile A;Lazzari L;Arnesano A;Trusolino L;Comoglio PM | |
| Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer | 2014 | S. Misale;S. Arena;S. Lamba;G. Siravegna;A. Lallo;S. Hobor;M. Russo;M. Buscarino;L. Lazzari;A. Sartore-Bianchi;K. Bencardino;A. Amatu;C. Lauricella;E. Valtorta;S. Siena;F. Di Nicolantonio;A. Bardelli | |
| Emergence of multiple EGFR extracellular mutations during cetuximab treatment in colorectal cancer | 2015 | S. Arena; B. Bellosillo; G. Siravegna; A. Martinez; I. Canadas; L. Lazzari; N. Ferruz; M. Russo; S. Misale; I. Gonzalez; M. Iglesias; E. Gavilan; G. Corti; S. Hobor; G. Crisafulli; M. Salido; J. Sanchez; A. Dalmases; J. Bellmunt; G.D. Fabritiis; A. Rovira; F. Di Nicolantonio; J. Albanell; A. Bardelli; C. Montagut | |
| Met-driven invasive growth involves transcriptional regulation of Arhgap12 | 2008 | Gentile A; D'Alessandro L; Lazzari L; Martinoglio B; Bertotti A; Mira A; Lanzetti L; Comoglio PM; Medico E. | |
| MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations | 2016 | Arena, Sabrina; Siravegna, Giulia; Mussolin, Benedetta; Kearns, Jeffrey D.; Wolf, Beni B.; Misale, Sandra; Lazzari, Luca; Bertotti, Andrea; Trusolino, Livio; Adjei, Alex A.; Montagut, Clara; Di Nicolantonio, Federica; Nering, Rachel; Bardelli, Alberto | |
| PO-050 A molecularly annotated platform of pdx-derived cell lines mirrors the genomic landscape of colorectal cancer | 2018 | Lazzari, L.; Corti, G.; Isella, C.; Montone, M.; Bertotti, A.; Trusolino, L.; Nicolantonio, F. Di; Linnebacher, M.; Bardelli, A.; Arena, S. | |
| RAF suppression synergizes with MEK inhibition in KRAS mutant cancer cells. | 2014 | Lamba S;Russo M;Sun C;Lazzari L;Cancelliere C;Grernrum W;Lieftink C;Bernards R;Di Nicolantonio F*;Bardelli A* (*co-last and * co-corresponding authors) | |
| Ron kinase transphosphorylation sustains MET oncogene addiction | 2011 | S. Benvenuti; L. Lazzari; A. Arnesano; G. Li Chiavi; A. Gentile; P.M. Comoglio | |
| Ror1 is a pseudokinase that is crucial for Met-driven tumorigenesis | 2011 | Gentile A; Lazzari L; Benvenuti S; Trusolino L*; Comoglio PM* (*Corresponding Authors) | |
| The ROR1 pseudokinase diversifies signaling outputs in MET-addicted cancer cells. | 2014 | Gentile A;Lazzari L;Benvenuti S;Trusolino L;Comoglio PM | |
| Tumor heterogeneity and Lesion-Specific response to targeted therapy in colorectal cancer | 2016 | Russo, Mariangela; Siravegna, Giulia; Blaszkowsky, Lawrence S.; Corti, Giorgio; Crisafulli, Giovanni; Ahronian, Leanne G.; Mussolin, Benedetta; Kwak, Eunice L.; Buscarino, Michela; Lazzari, Luca; Valtorta, Emanuele; Truini, Mauro; Jessop, Nicholas A.; Robinson, Hayley E.; Hong, Theodore S.; Mino-Kenudson, Mari; Di Nicolantonio, Federica; Thabet, Ashraf; Sartore-Bianchi, Andrea; Siena, Salvatore; Iafrate, John; Bardelli, Alberto; ^*; Corcoran, Ryan B.; ^*; ^ joint co-last authorship; *joint corresponding authorship | |
| Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer | 2020 | Lorenzato, Annalisa; Magrì, Alessandro; Matafora, Vittoria; Audrito, Valentina; Arcella, Pamela; Lazzari, Luca; Montone, Monica; Lamba, Simona; Deaglio, Silvia; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Bachi, Angela; Di Nicolantonio, Federica; Bardelli, Alberto; Arena, Sabrina |