The bronchodilating effect of magnesium sulfate (MgSO4) was studied in ten asthmatic patients with moderate to severe airway obstruction. Two grams of MgSO4 or saline in double-blind crossover design was administered IV for 20 minutes (0.40 mmol/min) and forced expiratory capacity and forced expiratory volume in one second (FEV1) were studied at intervals. Only at the end of MgSO4 infusion did FEV1 increase significantly (109% of initial values). The bronchodilating effect was short lasting and far less than that observed after salbutamol.
Acute effect of intravenous magnesium sulfate on airway obstruction of asthmatic patients / Rolla G.; Bucca C.; Caria E.; Arossa W.; Bugiani M.; Cesano L.; Caropreso A.. - In: ANNALS OF ALLERGY. - ISSN 0003-4738. - 61(1988), pp. 388-391.
Titolo: | Acute effect of intravenous magnesium sulfate on airway obstruction of asthmatic patients | |
Autori Riconosciuti: | ||
Autori: | Rolla G.; Bucca C.; Caria E.; Arossa W.; Bugiani M.; Cesano L.; Caropreso A. | |
Data di pubblicazione: | 1988 | |
Abstract: | The bronchodilating effect of magnesium sulfate (MgSO4) was studied in ten asthmatic patients with moderate to severe airway obstruction. Two grams of MgSO4 or saline in double-blind crossover design was administered IV for 20 minutes (0.40 mmol/min) and forced expiratory capacity and forced expiratory volume in one second (FEV1) were studied at intervals. Only at the end of MgSO4 infusion did FEV1 increase significantly (109% of initial values). The bronchodilating effect was short lasting and far less than that observed after salbutamol. | |
Volume: | 61 | |
Pagina iniziale: | 388 | |
Pagina finale: | 391 | |
Parole Chiave: | magnesium salbutamol bronchodilatation | |
Rivista: | ANNALS OF ALLERGY | |
Appare nelle tipologie: | 03A-Articolo su Rivista |